Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Laura Cristoferi, Alessandra Nardi, Pietro Invernizzi, George Mells, Marco Carbone
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Rodney A. Gabriel, Brittany N. Burton, Richard D. Urman, Ruth S. Waterman
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Sangeetha Prabhakaran, Joseph Leong, Nicholas J. Petrelli, Vijay P. Khatri
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Kimberly Aderhold, Melissa Wilson, Adam C. Berger, Shoshana Levi, Joseph Bennett
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Vijay P. Khatri, Nicholas J. Petrelli
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Timothy M. Pawlik
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s):
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s):
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s):
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s):
Wed Nov 20, 2019 18:19
Publication date: January 2020Source: Surgical Oncology Clinics of North America, Volume 29, Issue 1Author(s): Vijay P. Khatri, Nicholas J. Petrelli
Wed Nov 20, 2019 18:19
Abstract Purpose The efficacy and tolerability of adding chemotherapy to radiotherapy in the era of intensity-modulated radiation therapy (IMRT) remain controversial among older patients with nasopharyngeal carcinoma (NPC). The present study compared IMRT alone with IMRT in combination with chemotherapy in elderly NPC patients. Methods Between January 2011...
Wed Nov 20, 2019 02:00
Publication date: Available online 20 November 2019Source: European Journal of Surgical OncologyAuthor(s): Isabel T. Rubio, Michalis Kontos, M.J. Vrancken-Peeters, Roman Rouzier, Anita Rohini, Viviana Galimberti, Niels Kroman, Carmela Caballero, Shinji Ohno, BIG Task Force Surgical Trials
Wed Nov 20, 2019 16:53
Cancers, Vol. 11, Pages 1828: Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer Cancers doi: 10.3390/cancers11121828 Authors: Hu Chan Duan Wang Kong Dong Tsim Ginkgetin, a biflavone from Ginkgo biloba leaf, and resveratrol, a polyphenol found in grape and wine, are two phytochemicals being identified for its binding to vascular endothelial growth factor (VEGF): the binding, therefore, resulted...
Wed Nov 20, 2019 02:00
Abstract Early growth response-1 (EGR-1), also termed NEFI-A and Krox-24, as a multi-domain protein is implicated in several vital physiological processes, including development, metabolism, cell growth and proliferation. Previous studies have implied that EGR-1 was producing in response to the tissue injury, immune response and fibrosis. Meanwhile, emerging studies stressed the pronounced correlation of EGR-1 and human cancers. Nevertheless, the intricate mechanisms of cancer-reduce...
Wed Nov 20, 2019 02:00
Future Oncology, Ahead of Print.
Wed Nov 20, 2019 14:39
Abstract The effect of hepatitis C virus p7 trans‐regulated protein 3 (P7TP3) in the development of hepatocellular carcinoma (HCC) is still unknown. This study aimed to investigate the role and mechanism of P7TP3 in HCC. P7TP3 was significantly decreased in HCC tissues when compared with corresponding liver tissues just around the tumor (LAT) from 7 HCC patients. Fewer and smaller colonies were originated from HepG2‐P7TP3 cells when compared to HepG2‐NC cells. Overexpression of P7TP3 in HepG2 cells...
Wed Nov 20, 2019 12:18
Abstract The activity of transcriptional co‐activator with PDZ binding domain (TAZ) protein is strongly implicated in the pathogenesis of human cancer and is influenced by tumor metabolism. High levels of lactate concentration in tumor microenvironment due to metabolic reprogramming are inversely correlated with patient overall survival. Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis‐derived lactate efficiently increased TAZ expression and activity...
Tue Nov 19, 2019 21:00
Abstract According to cancer‐genome sequences, > 90% of cases of pancreatic ductal adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables accurate detection and quantification of rare mutations. We assessed the dynamics of circulating tumor DNA (ct‐DNA) in patients with advanced PDAC undergoing chemotherapy using dPCR. KRAS G12/13 mutation was assayed by dPCR in 47 paired tissue‐ and ct‐DNA samples. The 21 patients were subjected to quantitative ct‐DNA monitoring at 4–8‐week...
Tue Nov 19, 2019 20:59
Abstract Epstein‐Barr virus (EBV) is a well‐established tumor virus that has been implicated in a wide range of immunodeficiency‐associated lymphoproliferative disorders (LPDs). Although rituximab, a CD20 monoclonal antibody, has proven effective against EBV‐associated LPDs, prolonged use of this drug may lead to resistance due to the selective expansion of CD20‐negative cells. We have previously shown that cyclin‐dependent kinase (CDK) inhibitors are able to specifically suppress the expression...
Tue Nov 19, 2019 19:27
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