Abstract Amyloidosis is a well‐recognized entity, that can present as a systemic disease, or, uncommonly, as a localized mass. We report here, a rare presentation of amyloidosis presenting as a supraclavicular swelling, diagnosed on fine‐needle aspiration cytology. Subsequent bone marrow examination led to the diagnosis of multiple myeloma. This case highlights the need to be aware of cytological characteristics of amyloidosis, which can have unusual presentation posing a diagnostic dilemma.
Mon Nov 25, 2019 14:05
Abstract Background Many prior institutional and multi‐institutional studies have applied the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) retrospectively to their specimens to determine the risk of malignancy (ROM) of each category. Most of these studies focused on general assessment of the system and risk classification. However, there seems to be less focus on the category of atypia of undetermined significance (AUS) that could be attributed to the low number of cases that...
Mon Nov 25, 2019 14:12
Publication date: Available online 25 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Stephen R. Chorney, Julia F. Dailey, Karen B. ZurAbstractObjectivesTo determine the rate of significant respiratory events following adenoidectomy in young pediatric patients and to identify factors that would prompt inpatient admission postoperatively.MethodsA retrospective chart review was performed of consecutive adenoidectomy surgeries at a high-volume, tertiary-care children’s...
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Publication date: Available online 25 November 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Jostein Førsvoll, Einar Klæboe Kristoffersen, Knut ØymarAbstractObjectivesTonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. However, an immunological reason for this effect remains unknown. This literature review summarizes...
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The best facultative anaerobes among vertebrates are members of the genera Trachemys (pond slider turtles) and Chrysemys (painted turtles), and are able to survive without oxygen for up to 12 to 18 weeks at ∼3 °C. In this study, we utilized RNAseq to profile the transcriptomic changes that take place in response to 20 hrs of anoxia at 5 °C in the liver of the red eared slide turtle (Trachemys scripta elegans). Sequencing reads were obtained from at least 18,169 different genes and represented a minimum...
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Glaucoma is an age-dependent disease closely related to oxidative stress and is regarded as the second leading cause of irreversible blindness worldwide. In recent years, many studies have shown that morphological and functional abnormalities of the trabecular meshwork (TM) are closely related to glaucoma, especially with respect to oxidative stress. In this review, the mechanisms of oxidative stress in the TM and treatment strategies for this condition, including strategies involving antioxidants,...
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Background There are abundant sheep breed resources in the Xinjiang region of China attributing to its diverse ecological system, which include several high-litter size sheep populations. Previous studies have confirmed that the major high prolificacy gene cannot be used to detect high litter size. Our research team found a resource group in Pishan County, southern Xinjiang. It showed high fertility with an average litter size of two to four in one birth, excellent breast development,...
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Background Coelidiinae, a relatively large subfamily within the family Cicadellidae, includes 129 genera and ∼1,300 species distributed worldwide. However, the mitogenomes of only two species (Olidiana sp. and Taharana fasciana) in the subfamily Coelidiinae have been assembled. Here, we report the first complete mitogenome assembly of the genus Olidiana. Methods Specimens were collected from Wenxian County (Gansu Province,...
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Clear cell renal cell carcinoma (ccRCC) is one of the most common and lethal types of cancer within the urinary system. Great efforts have been made to elucidate the pathogeny. However, the molecular mechanism of ccRCC is still not well understood. The aim of this study is to identify key genes in the carcinogenesis and progression of ccRCC. The mRNA microarray dataset GSE53757 was downloaded from the Gene Expression Omnibus database. The GSE53757 dataset contains tumor and matched paracancerous...
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Caribbean reef corals have experienced unprecedented declines from climate change, anthropogenic stressors and infectious diseases in recent decades. Since 2014, a highly lethal, new disease, called stony coral tissue loss disease, has impacted many reef-coral species in Florida. During the summer of 2018, we noticed an anomalously high disease prevalence affecting different coral species in the northern portion of the Mexican Caribbean. We assessed the severity of this outbreak in 2018/2019 using...
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Background Foam roller and vibration techniques are currently used to assist in recovery after fatigue. The main purpose of this study was to determine the effects of the use of a foam roller with and without vibration on dynamic balance, ankle dorsiflexion, hamstring and lumbar spine flexibility and perceived knee and ankle stability after an induced fatigue protocol. Methods A total of 24 healthy recreationally active participants (17 males and seven females) were recruited to a randomized...
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Publication date: Available online 25 November 2019Source: Brain Research BulletinAuthor(s): Wen-jun Zhang, Zheng-ming Zhu, Zeng-xu LiuAbstractNeuropathic Pain (NPP) is caused by direct or indirect damage to the nervous system and is a common symptom of many diseases. Clinically, drugs are usually used to suppress pain, such as (lidocaine, morphine, etc.), but the effect is short-lived, poor analgesia, and there are certain dependence and side effects. Therefore, the investigation of the treatment...
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Inflammation in anterior uveitis is characterised by breakdown of the blood-ocular barrier, which allows leakage of blood constituents of higher molecular weight into the aqueous humour. In routine clinical ca...
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Obesity and its consequences are worldwide epidemic problem; therefore, studies with strategies and mechanisms that favor weight loss to improve outcomes in health are necessary. Effects of mushrooms on body w...
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Since the deinstitutionalization policy, in psychiatric hospitals, the care of patients with schizophrenia was left to their families which has been imposing a heavy burden on them. Family caregiver burden cou...
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Acute macular neuroretinopathy (AMN) is a rare retinal disease that produces transient or permanent visual impairment and occurs predominantly in young, Caucasian women of childbearing age. It is often characterized by wedge-like macular lesions. Although the cause of AMN is unknown, recent research suggests a microvascular etiology. Various vascular pathologies, including post-viral illness, oral contraceptives, and use of vasoconstrictive agents, have been associated with AMN. We present a case...
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Iris flocculi, a type of hereditary iris pigment epithelial cyst, have been reported in association with smooth muscle α-2 actin (ACTA2) gene as the causative gene of familial thoracic aortic aneurysm and dissections (FTAAD). The purpose of the report was to examine morphological changes in the shape of flocculi and iris features over time by comparing infants to adults with FTAAD combined with iris flocculi. A Japanese family with FTAAD and bilateral iris flocculi and the Arg149Cys gene mutation...
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Publication date: Available online 26 November 2019Source: Journal of VoiceAuthor(s): Thays Vaiano, Fernando A.M. Herbella, Mara BehlauSUMMARYBackgroundLow vertical larynx results in reduced musculoskeletal tension and easier vocal fold vibration what is critical not only for professional voice users but also for patients with dysphonia. High-resolution manometry (HRM) provides real time upper esophageal sphincter positioning as a surrogate for laryngeal location and it may be a tool for laryngeal...
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Publication date: Available online 26 November 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Robert D. Pesek, Sandeep K. Gupta
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Publication date: December 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 12Author(s):
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Publication date: December 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 12Author(s):
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Publication date: December 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 12Author(s): Maud T.A. Strous, Maryska L.G. Janssen-Heijnen, F. Jeroen Vogelaar
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Publication date: December 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 12Author(s): Aron Onerup, David Bock
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Publication date: December 2019Source: European Journal of Surgical Oncology, Volume 45, Issue 12Author(s):
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Abstract It is reported that black raspberry (BRB) anthocyanins could act as a potential chemopreventive agent for colorectal cancer (CRC). However, the underlying mechanism by which BRB anthocyanins inhibits the carcinogenesis of CRC cells has not been elucidated. The abnormal expression of microRNAs (miRNAs) that target important tumor suppressor genes is usually associated with CRC development. In this study, we explored whether BRB anthocyanins could affect the expression of certain miRNAs in...
Mon Nov 25, 2019 13:49
Related ArticlesActivity and safety of afatinib in a window preoperative EORTC study in patients with squamous cell carcinoma of the head and neck (SCCHN). Ann Oncol. 2018 04 01;29(4):985-991 Authors: Machiels JP, Bossi P, Menis J, Lia M, Fortpied C, Liu Y, Lhommel R, Lemort M, Schmitz S, Canevari S, De Cecco L, Guzzo M, Bianchi R, Quattrone P, Crippa F, Duprez T, Lalami Y, Quiriny M, de Saint Aubain N, Clement PM, Coropciuc R, Hauben E, Licitra LF Abstract...
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Related ArticlesKnockdown of Yin Yang 1 enhances anticancer effects of cisplatin through protein phosphatase 2A-mediated T308 dephosphorylation of AKT. Cell Death Dis. 2018 07 03;9(7):747 Authors: Zhao L, Li R, Gan YH Abstract Cisplatin is still one of the first-line drugs for chemotherapy of head and neck squamous cell carcinoma (HNSCC) and shows a survival advantage for HNSCC. However, a substantial proportion of HNSCC eventually becomes resistance...
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Related ArticlesEpithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer. Head Neck. 2018 10;40(10):2304-2313 Authors: Domingues CSDC, Serambeque BP, Laranjo Cândido MS, Marto CMM, Veiga FJB, Sarmento Antunes Cruz Ribeiro AB, Figueiras ARR, Botelho MFR, Dourado MARF Abstract BACKGROUND: Head and neck cancer is the sixth most common cancer worldwide, with oral squamous cell carcinoma (OSCC) being the most representative...
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Related ArticlesTRAF2 Cooperates with Focal Adhesion Signaling to Regulate Cancer Cell Susceptibility to Anoikis. Mol Cancer Ther. 2019 01;18(1):139-146 Authors: da Silva SD, Xu B, Maschietto M, Marchi FA, Alkailani MI, Bijian K, Xiao D, Alaoui-Jamali MA Abstract TRAF2, a RING finger adaptor protein, plays an important function in tumor necrosis factor (TNF)- and TNF-like weak inducer of apoptosis (TWEAK)-dependent signaling, in particular during inflammatory...
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Related ArticlesDevelopment of a semi-customized tongue displacement device using a 3D printer for head and neck IMRT. Radiat Oncol. 2019 May 14;14(1):79 Authors: Hong CS, Oh D, Ju SG, Ahn YC, Na CH, Kwon DY, Kim CC Abstract PURPOSE: To reduce radiation doses to the tongue, a patient-specific semi-customized tongue displacement device (SCTDD) was developed using a 3D printer (3DP) for head and neck (H&N) radiation therapy (RT). Dosimetric characteristics...
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Related ArticlesDevelopment of a high fidelity subglottic stenosis simulator for laryngotracheal reconstruction rehearsal using 3D printing. Int J Pediatr Otorhinolaryngol. 2019 Sep;124:134-138 Authors: Reighard CL, Green K, Powell AR, Rooney DM, Zopf DA Abstract INTRODUCTION: Laryngotracheal reconstruction (LTR) with cartilage graft augmentation is an effective treatment for subglottic stenosis and a critical advanced procedure for Pediatric Otolaryngologists....
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Related ArticlesTransoral robotic surgery for hilo-parenchymal submandibular stones: step-by-step description and reasoned approach. Int J Oral Maxillofac Surg. 2019 Dec;48(12):1520-1524 Authors: Capaccio P, Montevecchi F, Meccariello G, D'Agostino G, Cammaroto G, Pelucchi S, Vicini C Abstract The conservative transoral approach to hilo-parenchymal submandibular stones has been proposed as an alternative to traditional sialadenectomy. The main purpose...
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Related Articles[The value of multi-gene testing in benign or malign diagnosis of thyroid nodules with indeterminate cytology]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Oct 07;54(10):764-768 Authors: Song YT, Xu GH, Zhu YL, Ma TH, Yu H, Wang TX, Yu WB, Wei W, Zhang B Abstract Objective: To study the diagnostic value of a multi-gene molecular testing in cytologically indeterminate thyroid nodules. Methods: From February 2018 to September 2018,...
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Related Articles[Study on the method of microelectrodes implantation of artificial facial nerve prosthesis in closed mouth of orbicularis oris muscle in monkeys with facial nerve paralysis]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 Oct 09;54(10):670-675 Authors: Yu JB, Zhang TZ, Xu DY, Li KY Abstract Objective: To explore the optimal method of microelectrode implantation that can produce efficient mouth closure with microelectrode for orbicularis oris...
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Related Articles[Feasibility Research of the New Fixation Device Compatible with Head and Neck Coil of MRI for Radiotherapy]. Zhongguo Yi Liao Qi Xie Za Zhi. 2019 Sep 30;43(5):326-329 Authors: Tang H, Li G, Li C, Bai L, Hu Z, Bai S Abstract MRI simulation images quality of head and neck coil scanning is better than that of radiotherapy surface coil, but currently the head and neck coil is not compatible with radiotherapy positioning devices. In this...
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Related ArticlesNext-generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage-Multicenter experience. Head Neck. 2019 Nov 24;: Authors: Moore A, Bar Y, Maurice-Dror C, Ospovat I, Sarfaty M, Korzets Y, Goldvaser H, Gordon N, Billan S, Gutfeld O, Popovtzer A Abstract BACKGROUND: Salivary gland cancers (SGCs) are rare. The approach to metastatic patients is histology-dependent. There is little evidence on...
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Primary Spheno-Petro-Clival Tuberculosis. Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1796-1799 Authors: Verma H, Panda S, Sikka K, Irugu DVK, Thakar A Abstract The increase awareness and advent of anti-tuberculosis therapy led to decline in tuberculosis. Now a resurgence of tuberculosis is with immunosuppression and with resistant strains. The detection rate of extrapulmonary is increased with the advent of newer modalities of detection,...
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Locally advanced non-melanomatous skin cancer: Contemporary radiotherapeutic management. Oral Oncol. 2019 Nov 22;99:104443 Authors: McDowell L, Yom SS Abstract Non-melanomatous skin cancers (NMSC), comprising both cutaneous squamous cell carcinomas (SCC) and basal cell carcinomas (BCC), are the most common malignancies in fair-skinned persons, frequently arising in the sun-exposed head and neck region. Simple surgical excision is usually curative in...
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MR-based CT metal artifact reduction using Bayesian modelling. Phys Med Biol. 2019 Nov 25;: Authors: Nielsen JS, Edmund JM, Van Leemput K Abstract Metal artifact reduction (MAR) algorithms reduce the errors caused by metal implants in xray computed tomography (CT) images and are an important part of error management in radiotherapy (RT). A promising MAR approach is to leverage the information in magnetic resonance (MR) images that are acquired for organ...
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