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Πέμπτη 21 Νοεμβρίου 2019


Health-Related Internet Use Among Men With Prostate Cancer in Canada: Cancer Registry Survey Study.
Related ArticlesHealth-Related Internet Use Among Men With Prostate Cancer in Canada: Cancer Registry Survey Study. J Med Internet Res. 2019 Nov 19;21(11):e14241 Authors: Bender JL, Feldman-Stewart D, Tong C, Lee K, Brundage M, Pai H, Robinson J, Panzarella T Abstract BACKGROUND: After a prostate cancer diagnosis, men want information about their disease and treatment options. The internet offers a convenient means to deliver health information to patients...
pubmed: future oncology
Wed Nov 20, 2019 15:02
Toll-like receptor 3 -926T>A increased the risk of breast cancer through decreased transcriptional activity.
Related ArticlesToll-like receptor 3 -926T>A increased the risk of breast cancer through decreased transcriptional activity. Oncoimmunology. 2019;8(12):e1673126 Authors: Fan L, Zhou P, Chen AX, Liu GY, Yu KD, Shao ZM Abstract Toll-like receptor 3 (TLR3) is a viral sensor that induces apoptosis in response to double-stranded RNA (dsRNA). Common genetic changes in the TLR3 gene may influence breast cancer susceptibility and development. However, all...
pubmed: future oncology
Wed Nov 20, 2019 15:02
Systems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma.
Related ArticlesSystems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma. Oncoimmunology. 2019;8(12):e1665978 Authors: Leick KM, Obeid JM, Bekiranov S, Slingluff CL Abstract Background: We have identified, in melanomas, a set of genes encoding proteins that mediate mechanical barrier function in normal skin (barrier molecule genes, BMGs) and whose overexpression is associated with decreased immune signatures and shorter...
pubmed: future oncology
Wed Nov 20, 2019 15:02
Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study.
Related ArticlesEfficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study. Oncotarget. 2019 Nov 05;10(60):6526-6535 Authors: Piha-Paul SA, Taylor MH, Spitz D, Schwartzberg L, Beck JT, Bauer TM, Meric-Bernstam F, Purkayastha D, Karpiak L, Szpakowski S, Braiteh F Abstract Background: Phosphatidylinositol 3-kinase (PI3K) pathway activation plays a key role...
pubmed: future oncology
Wed Nov 20, 2019 15:02
Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort.
Related ArticlesProgrammed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort. Mod Pathol. 2019 Nov 18;: Authors: Thunnissen E, Kerr KM, Dafni U, Bubendorf L, Finn SP, Soltermann A, Biernat W, Cheney R, Verbeken E, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM,...
pubmed: future oncology
Wed Nov 20, 2019 13:01
Coley's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity.
Related ArticlesColey's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity. Semin Oncol. 2019 Nov 06;: Authors: Uher O, Caisova V, Hansen P, Kopecky J, Chmelar J, Zhuang Z, Zenka J, Pacak K Abstract There is no doubt that immunotherapy lies in the spotlight of current cancer research and clinical trials. However, there are still limitations in the treatment response in certain types of tumors largely...
pubmed: future oncology
Wed Nov 20, 2019 13:01
The Evolving Role of Radiotherapy for Head and Neck Cancer.
Related ArticlesThe Evolving Role of Radiotherapy for Head and Neck Cancer. Hematol Oncol Clin North Am. 2020 Feb;34(1):91-108 Authors: Schwartz DL, Hayes DN Abstract The length and quality of head and neck cancer survivorship continues to meaningfully improve. Radiotherapy has been central to this process through advances in treatment delivery, fractionation schemas, radiosensitizing systemic therapy, and thoughtful interplay with technical surgical...
pubmed: future oncology
Wed Nov 20, 2019 13:01
The Evolution (and Future) of Stereotactic Body Radiotherapy in the Treatment of Oligometastatic Disease.
Related ArticlesThe Evolution (and Future) of Stereotactic Body Radiotherapy in the Treatment of Oligometastatic Disease. Hematol Oncol Clin North Am. 2020 Feb;34(1):307-320 Authors: Onderdonk BE, Gutiontov SI, Chmura SJ Abstract This review outlines the history of the oligometastatic state from its first proposal to the current formulation. The article discusses the accumulating evidence for the biology of oligometastases, including clinical parameters,...
pubmed: future oncology
Wed Nov 20, 2019 13:01
Radiation Therapy for Thoracic Malignancies.
Related ArticlesRadiation Therapy for Thoracic Malignancies. Hematol Oncol Clin North Am. 2020 Feb;34(1):109-125 Authors: Lee VH, Yang L, Jiang Y, Kong FS Abstract Radiotherapy is the most commonly used nonsurgical modality in treatment of lung cancers, non-small cell lung cancer (NSCLC) in particular. Radiation therapy has been increasingly used as definitive radical treatment, either alone or in combination with concurrent chemoradiation for locally...
pubmed: future oncology
Wed Nov 20, 2019 13:01
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs.
Related Articles5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs. Nat Cell Biol. 2019 08;21(8):978-990 Authors: Chen X, Li A, Sun BF, Yang Y, Han YN, Yuan X, Chen RX, Wei WS, Liu Y, Gao CC, Chen YS, Zhang M, Ma XD, Liu ZW, Luo JH, Lyu C, Wang HL, Ma J, Zhao YL, Zhou FJ, Huang Y, Xie D, Yang YG Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its regulation and biological role in pathological...
pubmed: future oncology
Wed Nov 20, 2019 13:01
Connecting blood and intratumoral Treg cell activity in predicting future relapse in breast cancer.
Related ArticlesConnecting blood and intratumoral Treg cell activity in predicting future relapse in breast cancer. Nat Immunol. 2019 09;20(9):1220-1230 Authors: Wang L, Simons DL, Lu X, Tu TY, Solomon S, Wang R, Rosario A, Avalos C, Schmolze D, Yim J, Waisman J, Lee PP Abstract Regulatory T (Treg) cells play a major role in the development of an immunosuppressive tumor microenvironment. The origin of intratumoral Treg cells and their relationship with...
pubmed: future oncology
Wed Nov 20, 2019 13:01
Recent advances in triple negative breast cancer: the immunotherapy era.
Related ArticlesRecent advances in triple negative breast cancer: the immunotherapy era. BMC Med. 2019 05 09;17(1):90 Authors: Marra A, Viale G, Curigliano G Abstract BACKGROUND: Several accomplishments have been achieved in triple-negative breast cancer (TNBC) research over the last year. The phase III IMpassion130 trial comparing chemotherapy plus atezolizumab versus chemotherapy plus placebo brought breast cancer into the immunotherapy era. Nevertheless,...
pubmed: future oncology
Wed Nov 20, 2019 13:01
Variable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas.
Related ArticlesVariable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas. Hum Pathol. 2019 04;86:66-75 Authors: Leijon H, Remes S, Hagström J, Louhimo J, Mäenpää H, Schalin-Jäntti C, Miettinen M, Haglund C, Arola J Abstract Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are neuroendocrine tumors that express somatostatin receptors (SSTRs), a phenomenon that constitutes a basis for tumor imaging and...
pubmed: future oncology
Wed Nov 20, 2019 13:01

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