Related ArticlesOccurrence of blaCTX-M-15 extended-spectrum β-lactamase among clinical isolates of Klebsiella pneumoniae in Khorramabad, Iran. Infect Disord Drug Targets. 2019 Nov 19;: Authors: Goudarzi G, Shakib P Abstract OBJECTIVE: During the recent decade, CTX-M-type enzymes, primarily CTX-M-15 extended-spectrum β-lactamase (ESBL) have strikingly developed through the world. The objective of this study was to investigate the frequency of CTX-M-type...
Wed Nov 20, 2019 15:12
Related ArticlesThermodynamic profiling for fragment-based lead discovery and optimization. Expert Opin Drug Discov. 2019 Nov 19;:1-13 Authors: Ferenczy GG, Keserű GM Abstract Introduction: The enthalpic and entropic components of the ligand-protein binding free energy reflect the type and quality of the interactions and relate to the physicochemical properties of the ligands. These findings have significance in medicinal chemistry optimizations since...
Wed Nov 20, 2019 14:57
Related ArticlesAdvances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments. Expert Opin Drug Discov. 2019 Nov 19;:1-21 Authors: To KKW, Fong W, Tong CWS, Wu M, Yan W, Cho WCS Abstract Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the expression of their target genes by reducing mRNA stability and/or inhibiting translation. miRNAs are known to be aberrantly regulated in cancers....
Wed Nov 20, 2019 14:57
Related ArticlesLarge Sinonasal Schwannoma with Skull Base Defect: A Case Report. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):887-889 Authors: Subramanian N, Sood N, Ramalingam WVBS Abstract Unilateral sinonasal masses account for 6% of all paranasal sinus pathologies. We are reporting a case of nasoethmoidal schwannoma with a large skull base defect. The lesion was removed endoscopically along with repair of the defect. We are highlighting...
Wed Nov 20, 2019 14:48
Related ArticlesMasses of the Paranasal Sinuses After Treatment of Nasopharyngeal Carcinoma: A Case Report. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):406-409 Authors: Lazio MS, Cannavicci A, Squadrelli Saraceno M, Maggiore G Abstract The development of a new mass in the field of irradiation of a previously treated Nasopharyngeal carcinoma is generally considered a sign of recurrence. We report a case of a 46-year-old male, with a past...
Wed Nov 20, 2019 14:48
Related ArticlesMedical Graduate's Basic Knowledge and Clinical Skills Assessment in Otorhinolaryngology Post Internship. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):162-166 Authors: Qadri H, Andrabi DZ, Nemade SV, Shinde KJ, Naik C, Yeolekar A, Kahane K Abstract Exposure to otorhinolaryngology in India has been shadowed by an inadequate curriculum. Our study brings forth the lacunae in medical education setup related to ENT. We introspect...
Wed Nov 20, 2019 14:48
Related ArticlesIntraoperative Three-dimensional Virtual Reality and Computed Tomographic Guidance in Temporomandibular Joint Arthroplasty of Syndromic Craniofacial Dysostoses. Plast Reconstr Surg Glob Open. 2019 Sep;7(9):e2388 Authors: Bradley D, Willson T, Chang JB, Gandolfi B, Zhu TR, Bradley JP, Lee JC Abstract Bony ankylosis of the temporomandibular joints (TMJ) occurs in up to 28% of patients with syndromic mandibular dysostoses. Release of complete...
Wed Nov 20, 2019 14:48
Related ArticlesA radiologic review of hoarse voice from anatomic and neurologic perspectives. Insights Imaging. 2019 Nov 18;10(1):108 Authors: Montoya S, Portanova A, Bhatt AA Abstract The differential diagnosis for hoarseness is extensive and includes a multitude of etiologies that span a large geographic area from the brainstem to the mediastinum. Therefore, localizing a causative lesion can be extremely difficult for clinicians and radiologists alike....
Wed Nov 20, 2019 14:48
Related ArticlesTrans-septal suture retraction for endoscopic orbital surgery. Orbit. 2019 Nov 18;:1-6 Authors: Kim M, Gudis DA, Tooley A, Kazim M Abstract Purpose: We describe a novel technique for endonasal endoscopic orbital surgery. Previously described strategies for minimally invasive orbital surgery include mobilization of the medial rectus muscle and cryosurgical retraction of the pathologic lesion. Herein we describe endoscopic trans-septal...
Wed Nov 20, 2019 14:48
Related Articles[Occipital condyle syndrome: the visible part of the iceberg]. Pan Afr Med J. 2019;33:268 Authors: Raggabi A, Lalya I, Bourazza A Abstract Occipital condyle syndrome is a rare clinical disorder, clinically defined by the association of intense occipital headaches and paralysis of the twelfth paired cranial nerve. Its etiology is dominated by metastatic tumor. Imaging is the gold standard for diagnosis allowing to highlight occipital...
Wed Nov 20, 2019 14:48
Related ArticlesPig as a large animal model for posterior fossa surgery in oto-neurosurgery: A cadaveric study. PLoS One. 2019;14(2):e0212855 Authors: Elsayed M, Torres R, Sterkers O, Bernardeschi D, Nguyen Y Abstract This study proposes a practical model for a new approach to the posterior fossa in common domestic pigs. Several surgical procedures can be simulated in the nonliving pig model, including soft tissue dissection, drilling of temporal bone,...
Wed Nov 20, 2019 14:48
Related ArticlesDiagnosis of obstructive sleep apnea in women: Is there any difference?- Experience from a tertiary care hospital of North India. J Family Med Prim Care. 2019 Oct;8(10):3276-3281 Authors: Hashim Z, Nath A, Gupta M, Khan A, Mishra R, Srivastava S, Tripathi SK Abstract Context: Obstructive sleep apnea (OSA) considered classically to be a male-dominant disease, may have significant gender-based differences in clinical presentation and diagnosis....
Wed Nov 20, 2019 14:42
Related ArticlesDolichoarteriopathia of Bilateral Common Carotid Artery Presenting as Mass in Pyriform Fossae Causing Dysphagia: An Anatomical Anomaly. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):844-847 Authors: Ramadass T, Rao SA Abstract A rare case of aberrant tortuous common carotid artery (dolichoarteriopathia) presenting as submucosal swellings in bilateral pyriform sinuses, non-pulsatile, mimicking submucosal growths in an elderly...
Wed Nov 20, 2019 14:42
Related ArticlesApplication of Standardised Yoga Protocols as the Basis of Physiotherapy Recommendation in Treatment of Sleep Apneas: Moving Beyond Pranayamas. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):558-565 Authors: Kumar V, Malhotra V, Kumar S Abstract Yoga is an ancient Indian practice of mental and physical exercises (syn: asanas), postures (syn: mudras), movements and breathing techniques which sustain healthy living of the body...
Wed Nov 20, 2019 14:42
Related ArticlesNasopharyngeal Stenosis: A Rare Radiotherapy Complication. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):29-31 Authors: Nitassi S, Kissi M, Rkain I, Benbouzid A, Oujilal A, Essakalli L Abstract Introduction: Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal...
Wed Nov 20, 2019 14:42
Related ArticlesSexual Orientation and Sleep Behaviors in a National Sample of Adolescents Followed Into Young Adulthood. J Clin Sleep Med. 2019 Nov 15;15(11):1635-1643 Authors: Luk JW, Sita KR, Lewin D, Simons-Morton BG, Haynie DL Abstract STUDY OBJECTIVES: Sexual minority adolescents experience mental and physical health disparities attributable to increased discrimination and minority stress. These same factors may also impair sleep health, although...
Wed Nov 20, 2019 14:42
Related ArticlesFamilial Aggregation and Heritability of Obstructive Sleep Apnea Using Children Probands. J Clin Sleep Med. 2019 Nov 15;15(11):1561-1570 Authors: Au CT, Zhang J, Cheung JYF, Chan KCC, Wing YK, Li AM Abstract STUDY OBJECTIVES: Previous studies suggest the presence of familial aggregation of obstructive sleep apnea (OSA) in adults. However, similar data on childhood OSA are limited. This family study aimed to investigate the heritability...
Wed Nov 20, 2019 14:42
Related Articles"Barbed snore surgery" simulator: a low-cost surgical model. Eur Arch Otorhinolaryngol. 2019 Aug;276(8):2345-2348 Authors: Rinaldi V, Costantino A, Moffa A, Baptista P, Sabatino L, Casale M Abstract BACKGROUND: "Barbed snore surgery" (BSS) represents one of the last innovation for obstructive sleep apnea syndrome (OSAS) surgical management. Although this technique represents an effective and minimally invasive surgery, it is not still...
Wed Nov 20, 2019 14:42
Related ArticlesMenopausal transition bone loss- what are the practical implications. J Clin Endocrinol Metab. 2019 Nov 19;: Authors: Blumenfeld Z, Lavie G PMID: 31740937 [PubMed - as supplied by publisher]
Wed Nov 20, 2019 14:42
Automated analysis of bone-conduction cortical auditory evoked potential in normal-hearing neonates.
Related ArticlesAutomated analysis of bone-conduction cortical auditory evoked potential in normal-hearing neonates. Braz J Otorhinolaryngol. 2019 Oct 31;: Authors: Brito DS, Durante AS Abstract INTRODUCTION: The cortical auditory evoked potential allows the possibility of objectively evaluating the entire auditory system, which is desirable in the pediatric population. Bone conduction auditory stimulation is recommended in the differential diagnosis...
Wed Nov 20, 2019 14:42
Related ArticlesSecondary Acquired Nasolacrimal Duct Obstruction as a Specific Complication of Treatment With Radioactive Iodine (Morphological Study). Ophthalmic Plast Reconstr Surg. 2019 Nov 14;: Authors: Fedorov AA, Atkova EL, Yartsev VD Abstract PURPOSE: To conduct a morphological study of structural changes in nasolacrimal duct in secondary acquired nasolacrimal duct obstruction (SALDO) as a result of treatment with radioiodine. METHODS:...
Wed Nov 20, 2019 14:25
Related ArticlesMultifocal papillary thyroid cancer in children and adolescents: 12-year experience in a single center. Gland Surg. 2019 Oct;8(5):507-515 Authors: Chen J, Huang N, Ji Q, Wang Y, Zhu Y, Li D Abstract Background: Thyroid cancer is the most common endocrine malignant disease in children and adolescents. There is a trend of more conservative strategies including lobectomy and less radioactive iodine therapy (RAI) in multifocal papillary thyroid...
Wed Nov 20, 2019 14:25
Related ArticlesAssociation between Smoking and 30-Day Outcomes in Otologic Surgery. Otolaryngol Head Neck Surg. 2019 Nov 19;:194599819889622 Authors: Kay-Rivest E, Mascarella M, Sewitch MJ, Cloutier F, Mijovic T Abstract OBJECTIVE: To determine the effect of current smoking status on 30-day postoperative adverse events in patients undergoing otologic surgery. STUDY DESIGN: Retrospective cohort study. SETTING: Database of the American...
Wed Nov 20, 2019 14:24
Related ArticlesAppropriateness of Otic Quinolone Use among Privately Insured US Patients. Otolaryngol Head Neck Surg. 2019 Nov 19;:194599819889607 Authors: Tran PT, Winterstein AG, Wang X, Rhew K, Antonelli PJ Abstract OBJECTIVE: Considering emerging safety concerns involving otic quinolones, we assessed the extent of otic quinolone use for questionable indications. STUDY DESIGN: Descriptive cross-sectional study of a national sample of privately...
Wed Nov 20, 2019 14:24
Related ArticlesEpidemiology of Pediatric Tracheostomy and Risk Factors for Poor Outcomes: An 11-Year Single-Center Experience. Otolaryngol Head Neck Surg. 2019 Nov 19;:194599819887096 Authors: Chia AZH, Ng ZM, Pang YX, Ang AHC, Chow CCT, Teoh OH, Lee JH Abstract OBJECTIVE: Children with long-term tracheostomies are at higher risk of complications. This study aims to describe the epidemiology, outcomes, and factors associated with successful decannulation...
Wed Nov 20, 2019 14:24
Related ArticlesApproximate Weight of 1:1000 Topical Epinephrine on Wrung-Out Epinephrine-Soaked Pledgets. Otolaryngol Head Neck Surg. 2019 Nov 19;:194599819888651 Authors: Kuhar HN, Han X, Penning DH, Craig JR Abstract OBJECTIVE: Topical 1:1000 epinephrine solution is commonly applied intranasally with cottonoid pledgets in endoscopic sinonasal surgery for local vasoconstriction and hemostasis. Pledgets are typically submerged in epinephrine solution...
Wed Nov 20, 2019 14:24
Related ArticlesStudy of Pre and Post Operative Videostroboscopic Evaluation of Benign Vocal Cord Lesions. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):333-340 Authors: Sasindran V, Moosankutty S, Mathew N, George NS Abstract To determine pre and postoperative vocal fold vibratory changes using videostroboscopy (VS) and effect of surgery on functional, physical and emotional levels of voice using voice handicap index (VHI). To determine...
Wed Nov 20, 2019 18:17
Related ArticlesThe Clinicopathological Study of Benign Lesions of Vocal Cords. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):212-220 Authors: Malik P, Yadav SPS, Sen R, Gupta P, Singh J, Singla A, Vashisht S Abstract Benign vocal lesions are non-malignant growths of abnormal tissue on the vocal cords. The common benign lesions of vocal cord are singer's nodule, polyps, papilloma, polypoidal degeneration and cysts. The aim of this study was...
Wed Nov 20, 2019 18:17
Related ArticlesCorrection: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT. Oncotarget. 2019 Nov 05;10(60):6540 Authors: Li X, Teng S, Zhang Y, Zhang W, Zhang X, Xu K, Yao H, Yao J, Wang H, Liang X, Hu Z Abstract [This corrects the article DOI: 10.18632/oncotarget.16789.].PMID: 31741718 [PubMed - in process]
Wed Nov 20, 2019 16:18
Related ArticlesCorrection: A novel therapeutic approach to colorectal cancer in diabetes: role of metformin and rapamycin. Oncotarget. 2019 Nov 05;10(60):6538-6539 Authors: Geagea AG, Rizzo M, Jurjus A, Cappello F, Leone A, Tomasello G, Gracia C, Kattar SA, Massaad-Massade L, Eid A Abstract [This corrects the article DOI: 10.18632/oncotarget.26641.].PMID: 31741717 [PubMed - in process]
Wed Nov 20, 2019 16:18
Related ArticlesCorrection: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy. Oncotarget. 2019 Nov 05;10(60):6536-6537 Authors: Hsu TI, Chen YJ, Hung CY, Wang YC, Lin SJ, Su WC, Lai MD, Kim SY, Wang Q, Qian K, Goto M, Zhao Y, Kashiwada Y, Lee KH, Chang WC, Hung JJ Abstract [This corrects the article DOI: 10.18632/oncotarget.3701.].PMID: 31741716 [PubMed - in process]
Wed Nov 20, 2019 16:18
Related ArticlesEfficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study. Oncotarget. 2019 Nov 05;10(60):6526-6535 Authors: Piha-Paul SA, Taylor MH, Spitz D, Schwartzberg L, Beck JT, Bauer TM, Meric-Bernstam F, Purkayastha D, Karpiak L, Szpakowski S, Braiteh F Abstract Background: Phosphatidylinositol 3-kinase (PI3K) pathway activation plays a key role...
Wed Nov 20, 2019 16:18
Related ArticlesCharacterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma. Oncotarget. 2019 Nov 05;10(60):6509-6525 Authors: Fänder J, Kielstein H, Büttner M, Koelblinger P, Dummer R, Bauer M, Handke D, Wickenhauser C, Seliger B, Jasinski-Bergner S Abstract The multistructural and multifunctional transmembrane glycoprotein CD44 is overexpressed in many tumors of distinct origin including malignant melanoma and contributes...
Wed Nov 20, 2019 16:18
Related ArticlesSNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection. Oncotarget. 2019 Nov 05;10(60):6494-6508 Authors: Mijnes J, Tiedemann J, Eschenbruch J, Gasthaus J, Bringezu S, Bauerschlag D, Maass N, Arnold N, Weimer J, Anzeneder T, Fasching PA, Rübner M, Bruno B, Heindrichs U, Freres J, Schulz H, Hilgers RD, Ortiz-Brüchle N, von Serenyi S, Knüchel R, Kloten V, Dahl E Abstract Introduction: Mammography...
Wed Nov 20, 2019 16:18
Related ArticlesPre-surgical connectome features predict IDH status in diffuse gliomas. Oncotarget. 2019 Nov 05;10(60):6484-6493 Authors: Kesler SR, Harrison RA, Petersen ML, Rao V, Dyson H, Alfaro-Munoz K, Weathers SP, de Groot J Abstract Background: Gliomas are the most common type of malignant brain tumor. Clinical outcomes depend on many factors including tumor molecular characteristics. Mutation of the isocitrate dehydrogenase (IDH) gene confers...
Wed Nov 20, 2019 16:18
Related ArticlesMolecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence. Oncotarget. 2019 Nov 05;10(60):6466-6483 Authors: Yan W, Jamal M, Tan SH, Song Y, Young D, Chen Y, Katta S, Ying K, Ravindranath L, Woodle T, Kohaar I, Cullen J, Kagan J, Srivastava S, Dobi A, McLeod DG, Rosner IL, Sesterhenn IA, Srinivasan A, Srivastava S, Petrovics G Abstract ...
Wed Nov 20, 2019 16:18
Related ArticlesSecretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications. Oncotarget. 2019 Nov 05;10(60):6456-6465 Authors: Donnenberg AD, Luketich JD, Donnenberg VS Abstract INTRODUCTION: We compared the secretome of metastatic (non-small cell lung cancer (NSCLC)) and primary (mesothelioma) malignant pleural effusions, benign effusions and the published plasma profile of patients...
Wed Nov 20, 2019 16:18
Related ArticlesAssociation between ANGPTL-4 and the proinflammatory process in cancer cachexia patients. Oncotarget. 2019 Nov 05;10(60):6444-6455 Authors: Neto NIP, Boldarine VT, Hachul ACL, Oyama LM, Lima JDCC, Fernandez ES, Otoch JP, de Alcântara PSM, Tokeshi F, Seelaender MCL, Oller do Nascimento CMDP Abstract Background: Contradictory results are reported for the role of angiopoietin-like 4 (ANGPTL-4) in the development of cancer-cachexia and inflammation,...
Wed Nov 20, 2019 16:18
Related ArticlesThe anti-cancer effects of phenformin in thyroid cancer cell lines and in normal thyrocytes. Oncotarget. 2019 Nov 05;10(60):6432-6443 Authors: Coperchini F, Croce L, Denegri M, Awwad O, Ngnitejeu ST, Magri F, Chiovato L, Rotondi M Abstract Phenformin is a biguanide drug which, besides the original anti-diabetic effect, also exerts anti-cancer effects. The aim of this study was to further characterize these latter in terms of both cell-viability...
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