Objective Olfactory performance has rarely been assessed in the perioperative phase of elective aneurysm surgery. Here, we assessed the risk for olfactory deterioration following surgical treatment of unruptured cerebral aneurysm via the supraorbital keyhole craniotomy. Methods A retrospective review of patients with electively treated cerebral aneurysms who underwent perioperative assessment of olfactory function using a sniffin’ sticks odor identification test between 01/2015 and 01/2016...
Mon Nov 25, 2019 16:32
Introduction Over the past ten years, metacarpal fractures have had an annual incidence of 13.6 per 100,00 individuals. Literature has not reviewed anatomical variations through radiographic imaging, which may play a role in reducing postoperative complications. The purpose of this study was to use radiographic imaging to provide a detailed anatomy of the second through fifth metacarpals. Materials and Methods This retrospective study measured length, neck width, narrowest body width, and...
Mon Nov 25, 2019 16:32
Introduction The relation between pharyngeal tonsil and the bony nasopharynx determines the nasopharyngeal airway patency. Despite its importance, an anatomical study utilizing advanced imaging has not been conducted. The aim of the study was to evaluate the pharyngeal tonsil and bony nasopharynx depth and their ratio (ANR) with relation to sex and age in the general pediatric population. Materials and Methods After excluding reported history of adenoidectomy, acute upper airway illness, allergy,...
Mon Nov 25, 2019 16:44
Congenital heart disease is a rare but important finding in adults that experience sudden death. Examination of the congenitally malformed heart has historically been considered esoteric, and best left to those with expertise. The Cardiac Risk in the Young cardiovascular pathology laboratory based at St George's University of London has now received over 6000 cases. Of these, 21 congenitally malformed hearts were retained for research and educational purposes. Hearts were assessed using sequential...
Mon Nov 25, 2019 16:55
87 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/11/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Metaplastic Breast Carcinoma: Update on Histopathology and Molecular Alterations. Arch Pathol Lab Med. 2019 Dec;143(12):1492-1496 Authors: McMullen ER, Zoumberos NA, Kleer CG Abstract CONTEXT—: Metaplastic carcinoma is a rare, triple-negative carcinoma of the breast that exhibits transformation of part or all of its glandular carcinomatous component into a nonglandular, or metaplastic, component. The World Health Organization currently recognizes 5 variants...
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On the Importance of Continuing Medical Education. Arch Pathol Lab Med. 2019 Dec;143(12):1442-1443 Authors: Suster S PMID: 31765247 [PubMed - in process]
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Contemporary Renal Tumor Categorization With Biomarker and Translational Updates: A Practical Review. Arch Pathol Lab Med. 2019 Dec;143(12):1477-1491 Authors: Taylor AS, Spratt DE, Dhanasekaran SM, Mehra R Abstract CONTEXT.—: Renal tumor classification has evolved in recent decades, as evidenced by the comparable complexity of the 2016 revision to the World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs. A...
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Threats Remain. Arch Pathol Lab Med. 2019 Dec;143(12):1440-1441 Authors: Allen TC PMID: 31765249 [PubMed - in process]
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Ossifying Fibromyxoid Tumor: A Review With Emphasis on Recent Molecular Advances and Differential Diagnosis. Arch Pathol Lab Med. 2019 Dec;143(12):1504-1512 Authors: Carter CS, Patel RM Abstract CONTEXT.—: Ossifying fibromyxoid tumor (OFMT) is a rare, slow-growing mesenchymal neoplasm of uncertain histogenesis with intermediate malignant potential. OBJECTIVE.—: To highlight the most important diagnostic features, including morphologic, immunohistochemical,...
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Cellular Spindled Histiocytic Pseudotumor: A Benign Mimic of Spindle Cell Neoplasia of the Breast. Arch Pathol Lab Med. 2019 Dec;143(12):1497-1503 Authors: East EG, Carter CS, Sciallis AP Abstract CONTEXT.—: Cellular spindled histiocytic pseudotumor (CSHPT) is an exuberant, dense histiocytic proliferation seen in the setting of mammary fat necrosis. CSHPT has a broad histologic differential diagnosis, including benign, malignant, and inflammatory etiologies....
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Drug Discovery by Targeting Mutant KRAS. Curr Top Med Chem. 2019;19(23):2079-2080 Authors: Ye N PMID: 31762422 [PubMed - in process]
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Progress in the Mechanism and Clinical Application of Cilostazol. Curr Top Med Chem. 2019 Nov 22;: Authors: Zheng H, Yang H, Gong D, Mai L, Qiu X, Chen L, Su X, Wei R, Zeng Z Abstract Cilostazol is a unique platelet inhibitor that has been used clinically for more than 20 years. As a phosphodiesterase type III inhibitor, cilostazol is capable of reversible inhibition of platelet aggregation and vasodilation, has antiproliferative effects, and is widely...
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Abstract Claudins are the major component of tight junctions, which form a primary barrier to paracellular diffusion and maintain cell polarity in normal epithelia and endothelia. In cancer cells, claudins play additional roles besides serving as components of the tight junctions, and participate in anoikis or invasion. Among the claudin family proteins, claudin‐1 has the most promising potential, both diagnostically and prognostically, in many types of cancers, including oral, gastric, liver, and...
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Related ArticlesAmplicon-based next-generation sequencing of plasma cell-free DNA for detection of driver and resistance mutations in advanced non-small cell lung cancer. Ann Oncol. 2018 04 01;29(4):1049-1055 Authors: Guibert N, Hu Y, Feeney N, Kuang Y, Plagnol V, Jones G, Howarth K, Beeler JF, Paweletz CP, Oxnard GR Abstract Background: Genomic analysis of plasma cell-free DNA is transforming lung cancer care; however, available assays are limited...
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Related ArticlesManagement of metastatic retroperitoneal sarcoma: a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG). Ann Oncol. 2018 04 01;29(4):857-871 Authors: Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) Abstract Introduction: Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1%-0.2% of all malignancies. Management of RPS is complex and requires multidisciplinary, tailored...
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Related ArticlesA rare BRAF T599dup mutation conferring sensitivity to BRAF inhibitor in a patient with metastatic melanoma. Br J Dermatol. 2018 08;179(2):528-529 Authors: Marchand A, Tallet A, Collin C, Cormier B, Venel Y, Miquelestorena-Standley E, Machet L PMID: 29494756 [PubMed - indexed for MEDLINE]
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Related ArticlesEvaluation of treatment results in multifocal primary cutaneous anaplastic large cell lymphoma: report of the Dutch Cutaneous Lymphoma Group. Br J Dermatol. 2018 09;179(3):724-731 Authors: Melchers RC, Willemze R, Bekkenk MW, de Haas ERM, Horvath B, van Rossum MM, Sanders CJG, Veraart JCJM, Vermeer MH, Quint KD Abstract BACKGROUND: There is no consensus on the treatment of multifocal primary cutaneous anaplastic large cell lymphoma (C-ALCL)....
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Related ArticlesMagnetic Mesoporous Calcium Sillicate/Chitosan Porous Scaffolds for Enhanced Bone Regeneration and Photothermal-Chemotherapy of Osteosarcoma. Sci Rep. 2018 05 09;8(1):7345 Authors: Yang F, Lu J, Ke Q, Peng X, Guo Y, Xie X Abstract The development of multifunctional biomaterials to repair bone defects after neoplasm removal and inhibit tumor recurrence remained huge clinical challenges. Here, we demonstrate a kind of innovative and multifunctional...
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Related ArticlesPrognosis and nomogram for predicting postoperative survival of duodenal adenocarcinoma: A retrospective study in China and the SEER database. Sci Rep. 2018 05 21;8(1):7940 Authors: Jiang S, Zhao R, Li Y, Han X, Liu Z, Ge W, Dong Y, Han W Abstract As primary duodenal adenocarcinoma is rare, the prognostic factors of this disease remain insufficiently explored, especially in China. We identified postoperative duodenal adenocarcinoma...
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Related ArticlesIntrapancreatic accessory spleen: a diagnostic dilemma. HPB (Oxford). 2018 11;20(11):1004-1011 Authors: Li BQ, Xu XQ, Guo JC Abstract BACKGROUND: As intrapancreatic accessory spleen (IPAS) is rarely encountered during clinical practice, the aim of this review was to summarize the epidemiologic features, the diagnosis and treatment of IPAS. METHODS: MEDLINE and EMBASE were searched for articles reporting on IPAS. Categorical...
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Related ArticlesEvaluation of the vascular anatomy of the left-sided colon focused on the accessory middle colic artery: a single-centre study of 734 patients. Colorectal Dis. 2018 11;20(11):1041-1046 Authors: Miyake H, Murono K, Kawai K, Hata K, Tanaka T, Nishikawa T, Otani K, Sasaki K, Kaneko M, Emoto S, Nozawa H Abstract AIM: Surgery for colorectal cancer located in the splenic flexure is difficult to perform because of the complex anatomy. Recently,...
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Related ArticlesHuge Bursitis and Bursal Synovial Osteochondromatosis Associated With Scapular Osteochondroma Mimicking a Giant Calcific Mass of the Chest Wall. Am J Phys Med Rehabil. 2019 01;98(1):e1-e3 Authors: Tuncer K, Izgi E, Cankaya B, Ogul H, Kantarci M Abstract Osteochondroma is the most common benign bone tumor, but it rarely arises from the scapula. Scapulothoracic bursitis is quite rare and osteochondroma is one of the unusual causes of this...
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Related ArticlesReferral and treatment pathways for pseudomyxoma peritonei of appendiceal origin within a national treatment programme. Colorectal Dis. 2018 10;20(10):888-896 Authors: Fish R, Renehan AG, Punnett G, Aziz O, Fulford P, Selvasekar C, Wilson M, Halstead R, O'Dwyer ST Abstract AIM: Pseudomyxoma peritonei (PMP) is a rare neoplasm of the appendix, which if untreated disseminates throughout the abdominal cavity and generates considerable morbidity....
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Related ArticlesSocio-demographic, Clinical, and Genetic Determinants of Quality of Life in Lung Cancer Patients. Sci Rep. 2018 Jul 13;8(1):10640 Authors: Pierzynski JA, Ye Y, Lippman SM, Rodriguez MA, Wu X, Hildebrandt MAT Abstract Patient reported health-related quality of life (QOL) is a major component of the overall well-being of cancer patients, with links to prognosis. In 6,420 lung cancer patients, we identified patient characteristics and...
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Related ArticlesIntertriginous mastocytosis: a rare presentation of an uncommon disease. Int J Dermatol. 2019 Jul;58(7):852-853 Authors: Simmons BJ, LeBlanc RE, Glass JS PMID: 30079967 [PubMed - indexed for MEDLINE]
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Related ArticlesProptosis and hemiplegia as an initial manifestation of multiple myeloma. J Postgrad Med. 2018 Oct-Dec;64(4):243-246 Authors: Tahiliani N, Kataria P, Patel A, Kendre P Abstract Multiple myeloma (MM) is a monoclonal gammopathy, also known as the malignant proliferation of plasma cells, presenting with typical complications such as hypercalcemia, osteolytic bone lesions, anemia, renal insufficiency, and frequent infections. Central nervous...
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Related ArticlesImpact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer. Ann Oncol. 2018 10 01;29(10):2068-2075 Authors: Kron A, Alidousty C, Scheffler M, Merkelbach-Bruse S, Seidel D, Riedel R, Ihle MA, Michels S, Nogova L, Fassunke J, Heydt C, Kron F, Ueckeroth F, Serke M, Krüger S, Grohe C, Koschel D, Benedikter J, Kaminsky B, Schaaf B, Braess J, Sebastian M, Kambartel KO, Thomas R, Zander T, Schultheis AM, Büttner...
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Related ArticlesOvarian neuroendocrine carcinoma of metastatic origin: clues for diagnosis. Hum Pathol. 2019 03;85:309-312 Authors: Karpathiou G, Matias-Guiu X, Mobarki M, Vermesch C, Stachowicz ML, Chauleur C, Peoc'h M Abstract Neuroendocrine tumors of the ovary are rare and of uncertain histogenesis. They may be primary or metastatic. Pathogenesis of ovarian carcinomas remains unknown. We report the case of an ovarian large cell carcinoma expressing...
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Related ArticlesPrimary osteogenic sarcoma of the skull: Report of two cases with review of literature. J Postgrad Med. 2018 Oct-Dec;64(4):232-236 Authors: Singh R, Jha K, Pant I, Satti D Abstract Primary calvarial (excluding jaw) osteosarcoma is rare. We report two cases highlighting their unusual presentation and histopathologic variability - a 30-year-old female who presented with progressively increasing headache and a rapidly growing frontal swelling...
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Related ArticlesLymphomatoid granulomatosis: a rare lymphoproliferative disease in the pediatric age. Radiologia. 2019 Mar - Apr;61(2):179-180 Authors: Rocha Iñigo T, Sánchez Garduño JJ PMID: 30337062 [PubMed - indexed for MEDLINE]
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Related ArticlesA rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology. J Obstet Gynaecol. 2019 May;39(4):545-546 Authors: Sumigama S, Enomoto A, Matsukawa S, Ushida T, Imai K, Nakano T, Kotani T, Kikkawa F PMID: 30406702 [PubMed - indexed for MEDLINE]
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Related ArticlesColorectal premalignancy is associated with consensus molecular subtypes 1 and 2. Ann Oncol. 2018 10 01;29(10):2061-2067 Authors: Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, Guinney J, Dienstmann R, Vilar E Abstract Background: Gene expression-based profiling of colorectal cancer (CRC) can be used to identify four molecularly...
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Related ArticlesA case of severe, irreversible hypocalcemia after one dose of pamidronate administered for hypercalcemia of malignancy. J Oncol Pharm Pract. 2019 Oct;25(7):1787-1793 Authors: Kim S Abstract This is a case report of a patient who developed severe, irreversible hypocalcemia after receiving one dose of pamidronate 90 mg for hypercalcemia of malignancy. Hypocalcemia is a known risk of bisphosphonate treatments, but the incidence of severe...
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Related ArticlesHuman papillomavirus infection is not involved in esophageal verrucous carcinoma. Hum Pathol. 2019 03;85:50-57 Authors: Cappellesso R, Coati I, Barzon L, Peta E, Masi G, Scarpa M, Lanza C, Michelotto M, Ruol A, Cesaro S, Castoro C, Palù G, Nuovo GJ, Fassan M, Rugge M Abstract Verrucous carcinoma of the esophagus (VCE) is a rare variant of squamous cell cancer, with a puzzling clinical, etiological, and molecular profile. The etiological...
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Related ArticlesInterstitial pneumonitis associated with trastuzumab emtansine. J Oncol Pharm Pract. 2019 Oct;25(7):1798-1800 Authors: Alkan A Abstract Trastuzumab emtansine is an antibody-drug conjugate that is effective in human epidermal growth factor receptor-2 expressing advanced breast cancer. Trastuzumab emtansine is generally well tolerated and grade 3-4 toxicities are rare. Pulmonary complications were rarely reported. Here we present a patient...
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Related ArticlesPrognostic significance of Ki-67 levels and hormone receptor expression in low-grade serous ovarian carcinoma: an investigation of the Tumor Bank Ovarian Cancer Network. Hum Pathol. 2019 03;85:299-308 Authors: Sehouli J, Braicu EI, Richter R, Denkert C, Jank P, Jurmeister PS, Kunze CA, Budczies J, Darb-Esfahani S, Schmitt WD, Traut A, Grabowski J, Taube ET, Plett H Abstract Low-grade serous ovarian carcinoma (LGSOC) has recently come...
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Related ArticlesCortactin expression in non-Hodgkin B-cell lymphomas: a new marker for the differential diagnosis between chronic lymphocytic leukemia and mantle cell lymphoma. Hum Pathol. 2019 03;85:251-259 Authors: Pizzi M, Trentin L, Visentin A, Saraggi D, Martini V, Guzzardo V, Righi S, Frezzato F, Piazza F, Sabattini E, Semenzato G, Rugge M Abstract Cortactin is a cytoskeletal-remodeling adaptor protein, playing an oncogenic role in solid tumors....
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Related ArticlesMelanoma of the intestinal mucosa: A rare cause of obstruction. Cir Esp. 2019 May;97(5):294-295 Authors: García-Romera Á, Morales Hernández A, Medina-Arana V, Bravo Gutiérrez A, Alarcó A PMID: 30527737 [PubMed - indexed for MEDLINE]
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