Related ArticlesThe development of the cricoid cartilage and its implications for the use of endotracheal tubes in the pediatric population. Paediatr Anaesth. 2019 Nov 19;: Authors: Liu S, Qi W, Zhang X, Dong Y Abstract BACKGROUND: The rigid cricoid cartilage is functionally the narrowest portion of the larynx. There is some controversy over the shape of the pediatric cricoid cartilage in the transverse plane. It is important to understand the development...
Wed Nov 20, 2019 15:56
Related ArticlesFlexible nasopharyngolaryngoscopy: Evaluation and appraisal of its effectiveness and diagnostic yield, The Nigerian experience. J Family Med Prim Care. 2019 Oct;8(10):3399-3403 Authors: Aremu SK Abstract Background: Fiber-optic nasopahryngolaryngoscopy is a visual examination of the larynx and its related structures. It is an effective procedure for ascertaining the causes of laryngeal disorders, pain in the throat, and difficulty in...
Wed Nov 20, 2019 15:56
Related ArticlesLaryngeal Lipoma: A Clinicopathologic Case Report. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):876-878 Authors: Azimivaghar J, Javadirad E, Montazer S Abstract Lipoma is not usual in the head and neck and the intrinsic form of isolated laryngeal lipoma is quite rare. Because isolated laryngeal lipoma symptoms are uncharacteristic and often has no systemic manifestation, clinical diagnosis is difficult. We describe an extremely...
Wed Nov 20, 2019 15:56
Related ArticlesA Rare Case of Vocal Cord Aspergillosis. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):868-871 Authors: Chouksey S, Thulasidas P Abstract Primary aspergillosis of larynx is very rare. Till now only 28 cases of isolated laryngeal aspergillosis are documented in the English literature. In the field of otorhinolaryngology, aspergillosis most frequently affects external auditory canal or nasal sinuses and larynx is usually secondarily...
Wed Nov 20, 2019 15:56
Related ArticlesLaryngeal Leiomyosarcoma: A Rare Case. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):795-797 Authors: Ng BHK, Tang IP, Suhashini G, Chai CK Abstract Laryngeal leiomyosarcoma is a rare smooth muscle malignancy of the head and neck region. Diagnosis is based on immunohistochemistry. Here we present a case of laryngeal leiomyosarcoma that was diagnosed and treated in our center, focusing on the clinical features, histological...
Wed Nov 20, 2019 15:56
Related ArticlesConservative Curative Larynx Preserving Surgery for Subglottic Soft Tissue Recurrence Reinforced with Fascia-Lata and Strap Muscles. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):737-739 Authors: Mandlik D, Vatsyayan A, Patel P, Patel P, Patel K Abstract For early cancers of vocal cords, trans oral laryngeal surgery (TOLS) and curative radiotherapy (RT), have remained mainstay of treatment. Soft tissue recurrence in laryngeal...
Wed Nov 20, 2019 15:56
Related ArticlesSerum Adenosine Deaminase Levels and Human Papillomavirus as Prognostic and Predictive Factors for Laryngeal and Pharyngeal Carcinomas. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):522-527 Authors: Chandrakiran C, Jogy T, Patil SB Abstract Head and neck cancer is one of the most common cancers in the world, accounting for up to 30-40% malignancies in India. Research is always on the lookout for parameters that help in early...
Wed Nov 20, 2019 15:56
Related ArticlesEvaluation of Dynamic CT Scans and Analyzing Its Efficacy Accuracy in Staging of Laryngeal CA: A Prospective Analysis of 30 Patients and Review of Literature. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):265-275 Authors: Bharathi MB, Babu AR, Malik E Abstract Laryngeal and hypopharyngeal cancer is the most common cancer in the head and neck. It is the most commonly reported human malignancy, with more than 100,000 cases reported...
Wed Nov 20, 2019 15:56
Related ArticlesEvaluation of Stromal Myofibroblasts in Laryngeal Dysplasia and Invasive Squamous Cell Carcinoma. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):233-238 Authors: Orgen Calli A, Dere Y, Sari A, Dirilenoglu F, Onur I, İmre K Abstract Malignant tumors consist of both carcinoma cells and tumor associated host cells. Host cells has started to receive more attention regarding their role in tumor progression such as invasion and metastasis....
Wed Nov 20, 2019 15:56
Related ArticlesTolerance of Chemoradiation in Advanced Head and Neck Cancers: Comparison Between Inpatients and Outpatients. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):192-198 Authors: Suhag V, Sunita BS, Vats P, Chakravarty N, Pandya T, Lohia N Abstract Concurrent chemoradiation (CCRT) is the mainstay of treatment for majority of locally advanced head and neck carcinomas (LAHNC). Addition of chemotherapy to radiotherapy increases the...
Wed Nov 20, 2019 15:56
Related ArticlesLaryngocele: A Rare Case Report and Review of Literature. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):147-151 Authors: Juneja R, Arora N, Meher R, Mittal P, Passey JC, Saxena A, Bhargava EK Abstract Laryngocele is an abnormal cystic dilatation of the saccule of the larynx. It communicates with the laryngeal lumen and contains air. Laryngocele can be classified as internal (within the larynx), external (outside the larynx)...
Wed Nov 20, 2019 15:56
Related ArticlesNasopharyngeal Stenosis: A Rare Radiotherapy Complication. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):29-31 Authors: Nitassi S, Kissi M, Rkain I, Benbouzid A, Oujilal A, Essakalli L Abstract Introduction: Acquired nasopharyngeal stenosis after radiotherapy for NPC is rare. We report a case of bilateral choanal stenosis and nasopharygeal stenosis in patient treated with chemo radiotherapy for undifferentieted nasopharnygeal...
Wed Nov 20, 2019 15:56
Related ArticlesSmall-Cell Neuroendocrine Tumor of Larynx: A Rare Presentation. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):5-10 Authors: Pavan Kumar L, Armugham N, Rama Krishna M, Triveni B Abstract Here we report a 60 year aged male presented with complaints of right neck swelling of 3 months duration, swelling was initially small in size and gradually increasing. On examination right level II, hard mobile lymph node was palpable measuring...
Wed Nov 20, 2019 15:56
Related ArticlesA radiologic review of hoarse voice from anatomic and neurologic perspectives. Insights Imaging. 2019 Nov 18;10(1):108 Authors: Montoya S, Portanova A, Bhatt AA Abstract The differential diagnosis for hoarseness is extensive and includes a multitude of etiologies that span a large geographic area from the brainstem to the mediastinum. Therefore, localizing a causative lesion can be extremely difficult for clinicians and radiologists alike....
Wed Nov 20, 2019 13:59
Related ArticlesVocal fold fixation due to proximal stenosis progression complicating idiopathic subglottic stenosis. Eur Arch Otorhinolaryngol. 2019 Aug;276(8):2293-2300 Authors: Nouraei SAR, Dorman EB, Johnston J, Vokes DE Abstract PURPOSE: This study examined the incidence and risk factors for vocal fold fixation due to proximal progression of idiopathic subglottic stenosis (ISS) over the course of serial treatments. METHODS: Records of...
Wed Nov 20, 2019 13:59
Related ArticlesVocal fold scars: a common classification proposal by the American Laryngological Association and European Laryngological Society. Eur Arch Otorhinolaryngol. 2019 Aug;276(8):2289-2292 Authors: Hantzakos A, Dikkers FG, Giovanni A, Benninger MS, Remacle M, Sjögren EV, Woo P Abstract PURPOSE: Vocal fold scar is one the most challenging benign laryngeal pathologies. The purpose of this paper is to propose a classification that will allow...
Wed Nov 20, 2019 13:59
Related ArticlesMultiple airborne allergen-induced eosinophilic chronic rhinosinusitis murine model. Eur Arch Otorhinolaryngol. 2019 Aug;276(8):2273-2282 Authors: Park SC, Kim SI, Hwang CS, Cho HJ, Yoon JH, Kim CH Abstract PURPOSE: Several murine models have been established to mimic human eosinophilic chronic rhinosinusitis (ECRS). However, in most of these models, ECRS was induced using ovalbumin, which does not cause sinusitis in humans. Thus, we...
Wed Nov 20, 2019 13:59
Related ArticlesReprioritizing Risk and Benefit: The Future of Study Design in Early-Phase Cancer Research. Ethics Hum Res. 2019 Nov;41(6):2-11 Authors: Sisk BA, Dubois J, Hobbs BP, Kodish E Abstract The scientific purpose of phase I trials is to determine the maximum tolerated dose and/or optimal biological dose of experimental agents. Yet most participants in phase I oncology trials enroll hoping for direct medical benefit. The most common phase I...
Wed Nov 20, 2019 14:54
Related ArticlesWorkshop summary: Potential usefulness and feasibility of a US national mesothelioma registry. Am J Ind Med. 2019 Nov 19;: Authors: Cummings KJ, Becich MJ, Blackley DJ, Deapen D, Harrison R, Hassan R, Henley SJ, Hesdorffer M, Horton DK, Mazurek JM, Pass HI, Taioli E, Wu XC, Zauderer MG, Weissman DN Abstract BACKGROUND: The burden and prognosis of malignant mesothelioma in the United States have remained largely unchanged for decades,...
Wed Nov 20, 2019 14:54
Related ArticlesParaneoplastic Arthritides: Insights to Pathogenesis, Diagnostic Approach, and Treatment. J Clin Rheumatol. 2019 Nov 15;: Authors: Parperis K, Constantinidou A, Panos G Abstract Paraneoplastic arthritides are a group of inflammatory rheumatic syndromes induced by an occult and manifest malignancy, characterized by a wide range of musculoskeletal signs and symptoms that masquerade other rheumatic diseases such as rheumatoid arthritis....
Wed Nov 20, 2019 14:54
Related ArticlesHealth-Related Internet Use Among Men With Prostate Cancer in Canada: Cancer Registry Survey Study. J Med Internet Res. 2019 Nov 19;21(11):e14241 Authors: Bender JL, Feldman-Stewart D, Tong C, Lee K, Brundage M, Pai H, Robinson J, Panzarella T Abstract BACKGROUND: After a prostate cancer diagnosis, men want information about their disease and treatment options. The internet offers a convenient means to deliver health information to patients...
Wed Nov 20, 2019 14:54
Related ArticlesToll-like receptor 3 -926T>A increased the risk of breast cancer through decreased transcriptional activity. Oncoimmunology. 2019;8(12):e1673126 Authors: Fan L, Zhou P, Chen AX, Liu GY, Yu KD, Shao ZM Abstract Toll-like receptor 3 (TLR3) is a viral sensor that induces apoptosis in response to double-stranded RNA (dsRNA). Common genetic changes in the TLR3 gene may influence breast cancer susceptibility and development. However, all...
Wed Nov 20, 2019 14:54
Related ArticlesSystems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma. Oncoimmunology. 2019;8(12):e1665978 Authors: Leick KM, Obeid JM, Bekiranov S, Slingluff CL Abstract Background: We have identified, in melanomas, a set of genes encoding proteins that mediate mechanical barrier function in normal skin (barrier molecule genes, BMGs) and whose overexpression is associated with decreased immune signatures and shorter...
Wed Nov 20, 2019 14:54
Related ArticlesEfficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study. Oncotarget. 2019 Nov 05;10(60):6526-6535 Authors: Piha-Paul SA, Taylor MH, Spitz D, Schwartzberg L, Beck JT, Bauer TM, Meric-Bernstam F, Purkayastha D, Karpiak L, Szpakowski S, Braiteh F Abstract Background: Phosphatidylinositol 3-kinase (PI3K) pathway activation plays a key role...
Wed Nov 20, 2019 14:54
Related ArticlesProgrammed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort. Mod Pathol. 2019 Nov 18;: Authors: Thunnissen E, Kerr KM, Dafni U, Bubendorf L, Finn SP, Soltermann A, Biernat W, Cheney R, Verbeken E, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM,...
Wed Nov 20, 2019 13:53
Related ArticlesColey's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity. Semin Oncol. 2019 Nov 06;: Authors: Uher O, Caisova V, Hansen P, Kopecky J, Chmelar J, Zhuang Z, Zenka J, Pacak K Abstract There is no doubt that immunotherapy lies in the spotlight of current cancer research and clinical trials. However, there are still limitations in the treatment response in certain types of tumors largely...
Wed Nov 20, 2019 13:53
Related ArticlesThe Evolving Role of Radiotherapy for Head and Neck Cancer. Hematol Oncol Clin North Am. 2020 Feb;34(1):91-108 Authors: Schwartz DL, Hayes DN Abstract The length and quality of head and neck cancer survivorship continues to meaningfully improve. Radiotherapy has been central to this process through advances in treatment delivery, fractionation schemas, radiosensitizing systemic therapy, and thoughtful interplay with technical surgical...
Wed Nov 20, 2019 13:53
Related ArticlesThe Evolution (and Future) of Stereotactic Body Radiotherapy in the Treatment of Oligometastatic Disease. Hematol Oncol Clin North Am. 2020 Feb;34(1):307-320 Authors: Onderdonk BE, Gutiontov SI, Chmura SJ Abstract This review outlines the history of the oligometastatic state from its first proposal to the current formulation. The article discusses the accumulating evidence for the biology of oligometastases, including clinical parameters,...
Wed Nov 20, 2019 13:53
Related ArticlesRadiation Therapy for Thoracic Malignancies. Hematol Oncol Clin North Am. 2020 Feb;34(1):109-125 Authors: Lee VH, Yang L, Jiang Y, Kong FS Abstract Radiotherapy is the most commonly used nonsurgical modality in treatment of lung cancers, non-small cell lung cancer (NSCLC) in particular. Radiation therapy has been increasingly used as definitive radical treatment, either alone or in combination with concurrent chemoradiation for locally...
Wed Nov 20, 2019 13:53
Related ArticlesRecent advances in triple negative breast cancer: the immunotherapy era. BMC Med. 2019 05 09;17(1):90 Authors: Marra A, Viale G, Curigliano G Abstract BACKGROUND: Several accomplishments have been achieved in triple-negative breast cancer (TNBC) research over the last year. The phase III IMpassion130 trial comparing chemotherapy plus atezolizumab versus chemotherapy plus placebo brought breast cancer into the immunotherapy era. Nevertheless,...
Wed Nov 20, 2019 13:53
Related ArticlesVariable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas. Hum Pathol. 2019 04;86:66-75 Authors: Leijon H, Remes S, Hagström J, Louhimo J, Mäenpää H, Schalin-Jäntti C, Miettinen M, Haglund C, Arola J Abstract Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are neuroendocrine tumors that express somatostatin receptors (SSTRs), a phenomenon that constitutes a basis for tumor imaging and...
Wed Nov 20, 2019 13:53
Related ArticlesNew synthetic chitosan hybrids bearing some heterocyclic moieties with potential activity as anticancer and apoptosis inducers. Int J Biol Macromol. 2019 Nov 16;: Authors: El-Naggar MM, S A Haneen D, B M Mehany A, Khalil MT Abstract Wastes of the freshwater crayfish Procambarus clarkii were used as precursor for the extraction of chitin, which was deacetylation with alkali giving chitosan. Chitosan was transformed into the nanoparticles...
Wed Nov 20, 2019 14:46
Related ArticlesAntitumor activity of CDK inhibitor alsterpaullone in Epstein-Barr virus-associated lymphoproliferative disorders. Cancer Sci. 2019 Nov 19;: Authors: Watanabe T, Sato Y, Masud HMAA, Takayama M, Matsuda H, Hara Y, Yanagi Y, Yoshida M, Goshima F, Murata T, Kimura H Abstract Epstein-Barr virus (EBV) is a well-established tumor virus that has been implicated in a wide range of immunodeficiency-associated lymphoproliferative disorders (LPDs)....
Wed Nov 20, 2019 14:46
Related ArticlesDose-dependent cytotoxicity induced by pristine graphene oxide nanosheets for potential bone tissue regeneration. J Biomed Mater Res A. 2019 Nov 19;: Authors: Zhang X, Wei C, Li Y, Li Y, Chen G, He Y, Yi C, Wang C, Yu D Abstract This study was aimed to investigate the toxic effects of pristine graphene oxide (GO) nanosheets on bone-marrow-derived mesenchymal stem cells (BMSCs), a type of traditional seed cells in tissue regeneration engineering....
Wed Nov 20, 2019 14:46
Related ArticlesLayer-by-layer assembled PLGA nanoparticles carrying miR-34a cargo inhibit the proliferation and cell cycle progression of triple-negative breast cancer cells. J Biomed Mater Res A. 2019 Nov 19;: Authors: Kapadia CH, Ioele SA, Day ES Abstract Triple-negative breast cancer (TNBC) accounts for 15-25% of diagnosed breast cancers, and its lack of a clinically defined therapeutic target has caused patients to suffer from earlier relapse and...
Wed Nov 20, 2019 14:46
Related ArticlesRap1-mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence. Aging Cell. 2019 Nov 19;:e13061 Authors: Song S, Perez JV, Svitko W, Ricketts MD, Dean E, Schultz D, Marmorstein R, Johnson FB Abstract Cell senescence is accompanied, and in part mediated, by changes in chromatin, including histone losses, but underlying mechanisms are not well understood. We reported previously...
Wed Nov 20, 2019 14:46
Related ArticlesIn vitro anticancer activity Annona squamosa extract nanoparticle on WiDr cells. J Adv Pharm Technol Res. 2019 Oct-Dec;10(4):149-154 Authors: Fadholly A, Proboningrat A, Dewi Iskandar RP, Rantam FA, Sudjarwo SA Abstract This study aimed to prepare Annona squamosa leaf extract-loaded chitosan nanoparticles (nano-ASLE) against human colon cancer (WiDr) cells. Nano-ASLE was made with ionic gelation method. Four concentrations of the nano-ASLE...
Wed Nov 20, 2019 14:46
Related ArticlesCereal grass juice in wound healing: hormesis and cell-survival in normal fibroblasts, in contrast to toxic events in cancer cells. J Physiol Pharmacol. 2019 Aug;70(4): Authors: Karbarz M, Mytych J, Solek P, Stawarczyk K, Tabecka-Lonczynska A, Koziorowski M, Luczaj L Abstract Natural products and traditional medicines are of great importance. Recent studies have demonstrated, that cereal grass juice improves wound healing, however the...
Wed Nov 20, 2019 14:46
Related ArticlesBRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene. 2019 Nov 18;: Authors: Loveridge CJ, Slater S, Campbell KJ, Nam NA, Knight J, Ahmad I, Hedley A, Lilla S, Repiscak P, Patel R, Salji M, Fleming J, Mitchell L, Nixon C, Strathdee D, Neilson M, Ntala C, Bryson S, Zanivan S, Edwards J, Robson CN, Goodyear CS, Blyth K, Leung HY Abstract BRF1 is a rate-limiting factor for RNA Polymerase III-mediated transcription...
Wed Nov 20, 2019 13:48
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