Estimating the motions of the common carotid artery wall plays a very important role in early diagnosis of the carotid atherosclerotic disease. However, the disturbances caused by either the instability of the probe operator or the breathing of subjects degrade the estimation accuracy of arterial wall motion when performing speckle tracking on the B-mode ultrasound images. In this paper, we propose a global registration method to suppress external disturbances before motion estimation. The local...
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Background and Aims. Traditional Chinese medicine (TCM) has been widely applied in chronic hepatitis B (CHB) supplementary treatment in China. Kidney yang deficiency syndrome (KYDS), one of the most common TCM syndromes of CHB, is more likely to progress to liver cirrhosis or hepatocellular carcinoma than other syndromes. Polymorphisms in the human leucocyte antigen- (HLA-) DQB1 and -DRB1 genes were reported to be associated with hepatitis B virus infection outcomes. Here, we investigated whether...
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Abstract There is a growing research interest in quantifying blood flow distribution for the entire cerebral circulation to sharpen diagnosis and improve treatment options for cerebrovascular disease of individual patients. We present a methodology to reconstruct subject‐specific cerebral blood flow patterns in accordance with physiological and fluid mechanical principles and optimally informed by in vivo neuroimage data of cerebrovascular anatomy and arterial blood flow rates. We propose an ...
Tue Nov 19, 2019 16:46
Publication date: January 2020Source: Medical Image Analysis, Volume 59Author(s):
Wed Nov 20, 2019 19:53
Publication date: January 2020Source: Medical Image Analysis, Volume 59Author(s):
Wed Nov 20, 2019 19:53
Myopia is a very common condition in children, often progressing rapidly and triggering earlier onset of other eye conditions, such as cataracts and detached retina. Cooper Vision, a company out of Lake Forest, California, just won FDA clearance for the first contact lens that can actually slow down the progression of childhood myopia. Myopia is a result of the eye growing longer than it should, which causes the image to focus not on the retina, but in front of it. Indicated...
Wed Nov 20, 2019 17:50
Publication date: Available online 19 November 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): George E. Naoum, Laura Salama, Andrzej Niemierko, Bruno Lavajo Vieira, Yazid Belkacimi, Amy S. Colwell, Jonathan Winograd, Barbara Smith, Alice Ho, Alphonse G. TaghianAbstractObjectiveTo compare single-stage Direct to Implant (DTI) immediate reconstruction to the commonly used two-stages expander/implant (TE/I) or autologous reconstruction (AR) with focus on post-mastectomy...
Wed Nov 20, 2019 17:09
Publication date: Available online 19 November 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Angel Qin, Ramesh Rengan, Sylvia Lee, Rafael Santana-Davila, Bernardo H.L. Goulart, Renato Martins, Christina Baik, Gregory P. Kalemkerian, Khaled A. Hassan, Bryan J. Schneider, James A. Hayman, Shruti Jolly, Jason Hearn, Theodore S. Lawrence, Andrea M.H. Towlerton, Muneesh Tewari, Dafydd Thomas, Lili Zhao, Noah Brown, Timothy L. FrankelAbstractIntroductionPreclinical data...
Wed Nov 20, 2019 17:09
Wed Nov 20, 2019 16:05
Danio rerio (zebrafish) is an elective model organism for the study of vertebrate development because of its high degree of homology with human genes and organs, including bone. Zebrafish embryos, because of the optical clarity, small size, and fast development, can be easily used in large-scale mutagenesis experiments to isolate mutants with developmental skeletal defects and in high-throughput screenings to find new chemical compounds for the ability to revert the pathological phenotype. On the...
Wed Nov 20, 2019 12:05
Background Intragenomic variability in 16S rDNA is a limiting factor for taxonomic and diversity characterization of Bacteria, and studies on its occurrence in natural/environmental populations are scarce. In this work, direct DNA amplicon sequencing coupled with frequent-cutter restriction analysis allowed detection of intragenomic 16S rDNA variation in culturable endophytic bacteria from cacao seeds in a fast and attractive manner. ...
Wed Nov 20, 2019 02:00
Background Recent studies have shown that people with high alexithymia scores have decreased interoceptive abilities, which can be associated with psychological and physical disorders. Early assessments of the alexithymia trait included the evaluation of these abilities through the dimension measuring the difficulty in identifying and distinguishing between feelings and bodily sensations (the 26-item Toronto Alexithymia Scale; TAS-26). The revised version of the TAS, the TAS-20, contains a three-factor...
Wed Nov 20, 2019 02:00
Anthropogenic threat maps are commonly used as a surrogate for the ecological integrity of rivers in freshwater conservation, but a clearer understanding of their relationships is required to develop proper management plans at large scales. Here, we developed and validated empirical models that link the ecological integrity of rivers to threat maps in a large, heterogeneous and biodiverse Andean–Amazon watershed. Through fieldwork, we recorded data on aquatic invertebrate community composition, habitat...
Wed Nov 20, 2019 02:00
Oxidative stress can be reduced substantially using nanoantioxidant materials by tuning its surface morphological features up to a greater extent. The physiochemical, biological and optical properties of the nanoantioxidants can be altered by controlling their size and shape. In view of that, an appropriate synthesis technique should be adopted with optimization of the process variables. Properties of magnetite nanoparticles (IONP) can be tailored to upgrade the performance of biomedicine. Present...
Wed Nov 20, 2019 02:00
Purpose. To explore the effect of vascular stress changes on endothelial function recovery and vascular restenosis inhibition, under the condition of dynamic degradation process of the degradable stent. Methods. Fitting the material parameters of the hyperelastic vascular constitutive relationship, the stress distribution of the intima of the blood vessel before the stent was implanted and during the dynamic degradation was calculated by numerical simulation. In vitro culture experiments were carried...
Wed Nov 20, 2019 11:05
Nuclear envelope spectrin repeat protein 3 (nesprin-3) is an evolutionarily-conserved structural protein, widely-expressed in vertebrate cells. Along with other nesprin family members, nesprin-3 acts as an essential component of the linker of nucleoskeleton and cytoskeleton (LINC) complex. Naturally, nesprin-3 shares many functions with LINC, including the localization of various cellular structures and bridging of the nucleoskeleton and cytoskeleton, observed in vitro. When nesprin-3 was knocked...
Wed Nov 20, 2019 11:05
At the onset of legume-rhizobial symbiosis, the mutual recognition of partners occurs based on a complicated interaction between signal molecules and receptors. Bacterial signal molecules named Nod factors (“nodulation factors”) are perceived by the plant LysM-containing receptor-like kinases (LysM-RLKs) that recognize details of its structure (i.e., unique substitutions), thus providing the conditions particular to symbiosis. In the garden pea (Pisum sativum L.), the allelic state of Sym2 gene has...
Wed Nov 20, 2019 02:00
The mevalonate (MVA) pathway is responsible for the biosynthesis of cytosolic terpenes including gossypol and its derivatives, which play an important role in the cotton plant’s defense against pathogens and herbivores. In this study, we identified and cloned 17 potentially functional genes encoding enzymes that catalyze the six steps of the MVA pathway in Gossypium arboreum. Expression pattern analysis by qRT-PCR demonstrated that these genes had tissue-specific expression profiles and were most...
Wed Nov 20, 2019 02:00
Staphylococcus epidermidis is a human commensal and pathogen worldwide distributed. In this work, we surveyed for multi-resistant S. epidermidis strains in eight years at a children’s health-care unit in México City. Multidrug-resistant S. epidermidis were present in all years of the study, including resistance to methicillin, beta-lactams, fluoroquinolones, and macrolides. To understand the genetic basis of antibiotic resistance and its association with virulence and gene exchange, we sequenced...
Wed Nov 20, 2019 02:00
Correlation of parametrized image texture features (ITF) analyses conducted in different regions of interest (ROIs) overcomes limitations and reliably reflects image quality. The aim of this study is to propose a nonparametrical method and classify the quality of a magnetic resonance (MR) image that has undergone controlled degradation by using textural features in the image. Images of 41 patients, 17 women and 24 men, aged between 23 and 56 years were analyzed. T2-weighted sagittal sequences of...
Wed Nov 20, 2019 09:05
The digestive tract is home to millions of microorganisms and is the main and most important part of bacterial colonization. On one hand, the abundant bacterial community in intestinal tissues may pose potential health challenges such as inflammation and sepsis in cases of opportunistic invasion. Thus, the immune system has evolved and adapted to maintain the symbiotic relationship between host and microbiota. On the other hand, the intestinal microflora also exerts an immunoregulatory function to...
Wed Nov 20, 2019 09:05
Background. Liver transplantation (LT) is currently an effective treatment for end-stage liver disease, but the occurrence of acute rejection (AR) is still the main problem to be solved. The present study aimed to evaluate the effect of gastrodin (GAS) on LT. Methods. Rat transplant models were established and divided into SHAM, LT, GAS-L (50 mg/kg GAS), and GAS-H (100 mg/kg GAS) groups. The liver function, inflammatory factors, liver histopathology, survival of rats, number of M2-type macrophages,...
Wed Nov 20, 2019 09:05
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