Abstract Consensus has yet to be reached about the prevention and treatment of medication‐related osteonecrosis of the jaw (MRONJ), which is a treatment sequela of several antiresorptive therapies and other pharmaceutical interventions. Several epidemiologic studies have identified periodontal disease (PD) as a risk factor for this outcome. Thus, the objective of this systematic review and meta‐analysis was to investigate this association and its magnitude. A systematic search in MEDLINE via PubMed,...
Sat Oct 12, 2019 19:33
Abstract Background The adoption of the Chronic Oral Mucosal Disease Questionnaire (COMDQ) into clinical practice has been low, despite its rigorous development process. A potential limitation of the COMDQ is the high response burden to patients. Therefore, the aim of the present study was to develop and validate a short version of the 26‐item COMDQ. Methods The COMDQ data of 520 patients with chronic oral mucosal diseases were randomly divided into 2 subsamples. Descriptive item analysis...
Sat Oct 12, 2019 17:02
Abstract Objectives The aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil. Materials and methods A cross‐sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution time, clinical aspects, tumour location, tumour size at diagnosis, radiographic aspects and histopathological diagnosis were evaluated. Data were analysed using descriptive...
Sat Oct 12, 2019 17:12
Abstract Objective Proteasome activator 28γ (PA28γ) upregulation plays a critical role in the carcinogenesis of many malignancies, including oral cancer. We aim to screen the related genes of PA28γ and investigate their function in oral mucosa carcinogenesis. Materials and Methods Bioinformatics analysis was performed to screen the related genes of PA28γ. Immunohistochemical analysis was carried out to validate their correlation in oral squamous cell carcinoma (OSCC) and detect their expression...
Fri Oct 11, 2019 16:03
Abstract Objective The aim of this multicenter parallel‐group randomised controlled trial is to compare 6 mm short with 11 mm long implants in the rehabilitation of totally edentulous mandible in a completely comparable clinical situation, from anatomical, surgical and prosthetic point of view. Material and methods 30 patients were selected in three study centers to receive a fixed full‐arch mandibular rehabilitation supported by five interforaminal implants. Patients were randomly allocated,...
Sat Oct 12, 2019 11:04
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