- Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy.Related ArticlesIndibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Sci Rep. 2018 08 17;8(1):12363 Authors: Kapoor S, Srivastava S, Panda D Abstract Indibulin, a synthetic inhibitor of tubulin assembly, has shown promising anticancer activity with a minimal neurotoxicity in preclinical animal st
- The Current State of Animal Models in Research: A Review.Related ArticlesThe Current State of Animal Models in Research: A Review. Int J Surg. 2019 Oct 15;: Authors: Robinson NB, Krieger K, Khan F, Huffman W, Chang M, Naik A, Yongle R, Hameed I, Krieger K, Girardi LN, Gaudino M Abstract Animal models have provided invaluable information in the pursuit of medical knowledge and alleviation of human suffering. The foundations of our basic understanding of dis
- Commentary on: "Ensuring safe surgical care across resource settings via surgical outcomes data & quality improvement initiatives".Related ArticlesCommentary on: "Ensuring safe surgical care across resource settings via surgical outcomes data & quality improvement initiatives". Int J Surg. 2019 Oct 15;: Authors: Sarwar Shah SG PMID: 31627012 [PubMed - as supplied by publisher]
- Commentary to: "Role of preoperative vitamin D supplementation in reducing post thyroidectomy hypocalcemia; Cohort Study".Related ArticlesCommentary to: "Role of preoperative vitamin D supplementation in reducing post thyroidectomy hypocalcemia; Cohort Study". Int J Surg. 2019 Oct 15;: Authors: Gambardella C, Docimo L PMID: 31627011 [PubMed - as supplied by publisher]
- Commentary on "Postoperative outcomes in elderly patients undergoing pancreatic resection for pancreatic adenocarcinoma: A systematic review and meta-analysis".Related ArticlesCommentary on "Postoperative outcomes in elderly patients undergoing pancreatic resection for pancreatic adenocarcinoma: A systematic review and meta-analysis". Int J Surg. 2019 Oct 15;: Authors: Birk JW PMID: 31627010 [PubMed - as supplied by publisher]
- Commentary on ''Systematic assessment of complications after robotic-assisted total versus distal gastrectomy for advanced gastric cancer: A retrospective propensity score-matched study using Clavien-Dindo classification''.Related ArticlesCommentary on ''Systematic assessment of complications after robotic-assisted total versus distal gastrectomy for advanced gastric cancer: A retrospective propensity score-matched study using Clavien-Dindo classification''. Int J Surg. 2019 Oct 15;: Authors: Augustin G PMID: 31627009 [PubMed - as supplied by publisher]
- Closure of mesenteric defects is associated with a higher incidence of small bowel obstruction due to adhesions after laparoscopic antecolic Roux-en-y gastric bypass: a retrospective cohort study: A Commentary on the article.Related ArticlesClosure of mesenteric defects is associated with a higher incidence of small bowel obstruction due to adhesions after laparoscopic antecolic Roux-en-y gastric bypass: a retrospective cohort study: A Commentary on the article. Int J Surg. 2019 Oct 15;: Authors: Gould L, Parmar C PMID: 31627008 [PubMed - as supplied by publisher]
- upper respiratory tract infection; +22 new citations22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/10/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
- Masseteric or facial nerve? Intricacies in dynamic facial reanimation.Related ArticlesMasseteric or facial nerve? Intricacies in dynamic facial reanimation. J Plast Reconstr Aesthet Surg. 2019 Oct 01;: Authors: Nagrath N, Ghanem A PMID: 31623986 [PubMed - as supplied by publisher]
- Reel it in: A readily available and high-fidelity model for microvascular training.Related ArticlesReel it in: A readily available and high-fidelity model for microvascular training. J Plast Reconstr Aesthet Surg. 2019 Oct 01;: Authors: Baker BG, Patel N, Jeevan R PMID: 31623985 [PubMed - as supplied by publisher]
- Quantifying normal head form and craniofacial asymmetry of elementary school students in Taiwan.Related ArticlesQuantifying normal head form and craniofacial asymmetry of elementary school students in Taiwan. J Plast Reconstr Aesthet Surg. 2019 Sep 24;: Authors: Hsu CK, Hallac RR, Denadai R, Wang SW, Kane AA, Lo LJ, Chou PY Abstract BACKGROUND: Defining three-dimensional (3D) normal craniofacial morphology in healthy children could provide craniofacial surgeons a reference point to assess disea
- Future Oncology; +21 new citations21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/10/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
- Oncology Nurses' Attitudes and Engagement in Nursing Research.Related ArticlesOncology Nurses' Attitudes and Engagement in Nursing Research. Oncol Nurs Forum. 2019 Nov 01;46(6):727-737 Authors: Arthur EK, Brown CG, Martz L, Weatherby L, Purcell T, Dove J, Ridgway E, Cheriki M, Sinnott L, Rosselet R Abstract OBJECTIVES: To assess nurses' attitudes and perceptions about research. SAMPLE & SETTING: 623 RNs at a National Cancer Institute-designated com
- Trajectories of social resource use among informal lung cancer caregivers.Related ArticlesTrajectories of social resource use among informal lung cancer caregivers. Cancer. 2019 Oct 18;: Authors: Litzelman K, Reblin M, McDowell HE, DuBenske LL Abstract BACKGROUND: Social support is a key component in maintaining cancer caregiver well-being, and many resources exist to facilitate caregivers' use of social support (eg, cancer support groups). This study sought to determine h
- Association of Chemoradiotherapy Regimens and Survival Among Patients With Nasopharyngeal Carcinoma: A Systematic Review and Meta-analysis.Related ArticlesAssociation of Chemoradiotherapy Regimens and Survival Among Patients With Nasopharyngeal Carcinoma: A Systematic Review and Meta-analysis. JAMA Netw Open. 2019 Oct 02;2(10):e1913619 Authors: Zhang B, Li MM, Chen WH, Zhao JF, Chen WQ, Dong YH, Gong X, Chen QY, Zhang L, Mo XK, Luo XN, Tian J, Zhang SX Abstract Importance: The role of induction chemotherapy (IC) or adjuvant chemotherapy
- Sedation practices in pediatric patients with acute lymphoblastic leukemia.Related ArticlesSedation practices in pediatric patients with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2019 Oct 18;:e28037 Authors: Nugent BD, Davis PJ, Noll RB, Tersak JM Abstract BACKGROUND: The 5-year survival for pediatric acute lymphoblastic leukemia (ALL) is greater than 90%. One late effect of pediatric ALL associated with numerous long-term difficulties is neurocognitive deficits.
- Lenalidomide maintenance post-transplantation in newly diagnosed multiple myeloma: real-world outcomes and costs.Related ArticlesLenalidomide maintenance post-transplantation in newly diagnosed multiple myeloma: real-world outcomes and costs. Future Oncol. 2019 Oct 18;: Authors: Hari P, Ung B, Abouzaid S, Agarwal A, Parikh K Abstract Aim: To compare real-world outcomes and costs among patients with newly diagnosed multiple myeloma receiving lenalidomide-only maintenance (Len-Mt) versus no maintenance after auto
- Addition of Bevacizumab to First-Line Palliative Chemotherapy in Patients with Metastatic Small Bowel Adenocarcinoma: A Population-Based Study.Related ArticlesAddition of Bevacizumab to First-Line Palliative Chemotherapy in Patients with Metastatic Small Bowel Adenocarcinoma: A Population-Based Study. Target Oncol. 2019 Oct 17;: Authors: Legué LM, van Erning FN, Bernards N, Lemmens VEPP, de Hingh IHJT, Creemers GJ Abstract BACKGROUND: Data about the use and effectiveness of targeted therapy in metastatic small bowel adenocarcinoma (SBA) are
- The hubris and humility of cancer pharmacology in the post immuno-oncology era.Related ArticlesThe hubris and humility of cancer pharmacology in the post immuno-oncology era. Pharmacol Res Perspect. 2019 Dec;7(6):e00527 Authors: Lazo JS Abstract Cancer is a dreaded word, which has stimulated monumental efforts to discover and deliver effective cancer treatments for more than half a century. During the past two decades, our understanding of the molecular pathogenesis of cancer h
- Complete remission with ibrutinib after allogeneic stem cell transplant for central nervous system relapse of mantle cell lymphoma: A case report and literature review.Related ArticlesComplete remission with ibrutinib after allogeneic stem cell transplant for central nervous system relapse of mantle cell lymphoma: A case report and literature review. Clin Case Rep. 2019 Oct;7(10):1957-1961 Authors: Rich JD, Clark SM, Fedoriw Y, Jewells V, Wood W, Dittus C Abstract Central nervous system (CNS)-relapsed mantle cell lymphoma (MCL) is a rare, aggressive non-Hodgkin lym
- Suppressing immunotherapy by organ-specific tumor microenvironments: what is in the brain?Related ArticlesSuppressing immunotherapy by organ-specific tumor microenvironments: what is in the brain? Cell Biosci. 2019;9:82 Authors: Zhang C, Yu D Abstract Recent breakthroughs in cancer immunotherapy have led to curative efficacy and significantly prolonged survival in a subset of patients of multiple cancer types; and immunotherapy has become the newest pillar of cancer treatment in addition
- Different patterns of epileptiform-like activity are generated in the sclerotic hippocampus from...Different patterns of epileptiform-like activity are generated in the sclerotic hippocampus from patients with drug-resistant temporal lobe epilepsy.Related ArticlesDifferent patterns of epileptiform-like activity are generated in the sclerotic hippocampus from patients with drug-resistant temporal lobe epilepsy. Sci Rep. 2018 05 08;8(1):7116 Authors: Reyes-Garcia SZ, Scorza CA, Araújo NS, Ortiz-Villatoro NN, Jardim AP, Centeno R, Yacubian EMT, F
- Monalizumab: inhibiting the novel immune checkpoint NKG2A.Related ArticlesMonalizumab: inhibiting the novel immune checkpoint NKG2A. J Immunother Cancer. 2019 Oct 17;7(1):263 Authors: van Hall T, André P, Horowitz A, Ruan DF, Borst L, Zerbib R, Narni-Mancinelli E, van der Burg SH, Vivier E Abstract The implementation of immune checkpoint inhibitors to the oncology clinic signified a new era in cancer treatment. After the first indication of melanoma, an inc
- Cost burden of diffuse large B-cell lymphoma.Related ArticlesCost burden of diffuse large B-cell lymphoma. Expert Rev Pharmacoecon Outcomes Res. 2019 Oct 18;: Authors: Harkins RA, Patel SP, Flowers CR Abstract INTRODUCTION: Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma and is a clinically heterogenous disease. Treatment pathways for DLBCL are diverse and integrate established and novel therapies. Areas covered: W
- Augmenting the randomized controlled trial with real-world data to aid clinical decision making in metastatic renal cell carcinoma: a systematic review and meta-analysis.Related ArticlesAugmenting the randomized controlled trial with real-world data to aid clinical decision making in metastatic renal cell carcinoma: a systematic review and meta-analysis. Future Oncol. 2019 Oct 18;: Authors: Moran M, Nickens D, Adcock K, Bennetts M, Charnley N, Fife K Abstract Aim: To evaluate how efficacy outcomes from real-world data (RWD) can support those from randomized controlle
- Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists.Related ArticlesImmunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists. Viruses. 2019 Oct 03;11(10): Authors: Backhaus PS, Veinalde R, Hartmann L, Dunder JE, Jeworowski LM, Albert J, Hoyler B, Poth T, Jäger D, Ungerechts G, Engeland CE Abstract Tumor-targeted immunomodulation using oncolytic viral vectors is currently bein
- Microfluidic Technologies for cfDNA Isolation and Analysis.Related ArticlesMicrofluidic Technologies for cfDNA Isolation and Analysis. Micromachines (Basel). 2019 Oct 03;10(10): Authors: Xu Z, Qiao Y, Tu J Abstract Cell-free DNA (cfDNA), which promotes precision oncology, has received extensive concern because of its abilities to inform genomic mutations, tumor burden and drug resistance. The absolute quantification of cfDNA concentration has been proved as
- The Biological Mechanisms of Action of Cardiac Progenitor Cell Therapy.Related ArticlesThe Biological Mechanisms of Action of Cardiac Progenitor Cell Therapy. Curr Cardiol Rep. 2018 08 13;20(10):84 Authors: Pagano F, Picchio V, Angelini F, Iaccarino A, Peruzzi M, Cavarretta E, Biondi-Zoccai G, Sciarretta S, De Falco E, Chimenti I, Frati G Abstract PURPOSE OF REVIEW: Cell therapy for cardiovascular diseases is regarded as a rapidly growing field within regenerative medic
- Cardiopulmonary Impairments Caused by a Large Hiatal Hernia with Organoaxial Gastric Volvulus Showing Upside-Down Stomach: A Case Report.Related ArticlesCardiopulmonary Impairments Caused by a Large Hiatal Hernia with Organoaxial Gastric Volvulus Showing Upside-Down Stomach: A Case Report. Am J Case Rep. 2019 Oct 18;20:1530-1535 Authors: Umemura A, Suto T, Fujiwara H, Ikeda K, Nakamura S, Hayano M, Nitta H, Takahara T, Hasegawa Y, Katagiri H, Kanno S, Sasaki A Abstract BACKGROUND Upside-down stomach (UDS) is the rarest type of hiatal
- Alexithymia: A facet of uncontrolled hypertensionPublication date: Available online 19 October 2019Source: International Journal of PsychophysiologyAuthor(s): Maria Casagrande, Alessandro Mingarelli, Angela Guarino, Francesca Favieri, Ilaria Boncompagni, Rosanna Germanò, Giuseppe Germanò, Giuseppe ForteAbstractIntroductionProper control of blood pressure reduces the risk of developing cardiovascular and cerebrovascular complications in hypertensive people. However, this control remains mostly u
- The Current and Future Use of Telemedicine in Infectious Diseases PracticeAbstract Purpose of Review Novel technologies, such as high-definition cameras, encryption software, electronic stethoscopes, microfluidic diagnostic systems, and widely available broadband Internet have expanded the potential for telemedicine. This narrative review presents current and future uses of telemedicine in the prevention, diagnosis, treatment, stewardship, and manageme
- Translation, Validity, and Reliability of the Persian Version of the Aging Voice IndexPublication date: Available online 18 October 2019Source: Journal of VoiceAuthor(s): Akram Ahmadi, Shamim Hosseinifar, Maryam Faham, Mohammad Moez Shahramnia, Abbas Ebadi, Nicole M. Etter, Amir Shiani, Mehdi DehghanAbstractObjectivesThe Aging Voice Index (AVI) was developed to study quality of life in older adults with voice disorders. The purpose of this study was to translate the original English version of the AVI to Persian version of Aging V
- The role of epigenetics in allergy and asthma developmentPurpose of review Epigenetic mechanisms are known to play a crucial role in the pathogenesis of asthma, allergic rhinitis, atopic dermatitis, food allergy, and other allergic disorders, especially through mediating the effects of the environmental factors, well recognized allergy-risk modifiers. The aim of this work was to provide a concise but comprehensive review of the recent progress in the epigenetics of allergic diseases. Recent findin
- Pulmonary rehabilitation: promising nonpharmacological approach for treating asthma?Purpose of review Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation with a history of respiratory symptoms that vary over time and in intensity, together with variable expiratory airflow limitation. The goal of asthma treatment is to reach symptoms control, reduction in future risk and improvement in quality of life (QoL). Guideline-based pharmacologic therapies and the effect of inhaled steroids and bronc
- Large DNA virus promoted the endosymbiotic evolution to make a photosynthetic eukaryote [NEW RESULTS]Chloroplasts in photosynthetic eukaryotes originated from a cyanobacterial endosymbiosis far more than 1 billion years ago1-3. Due to this ancientness, it remains unclear how this evolutionary process proceeded. To unveil this mystery, we analysed the whole genome sequence of a photosynthetic rhizarian amoeba4, Paulinella micropora5,6, which has a chloroplast-like organelle that originated from another cyanobacterial endosymbiosis7-10 about 0.1 b
- In vivo study of metabolic dynamics and heterogeneity in brown and beige fat by label‐free multiphoton redox and fluorescence lifetime microscopyAbstract In this work, the metabolic characteristics of adipose tissues in live mouse model were investigated using a multiphoton redox ratio and fluorescence lifetime imaging technology. By analyzing the intrinsic fluorescence of metabolic coenzymes, we measured the optical redox ratios of adipocytes in vivo and studied their responses to thermogenesis. The fluorescence lifetime imaging further revealed changes in protein‐bindings of metabolic
- Assessment of corneal viscoelasticity using elastic wave optical coherence elastographyAbstract The corneal viscoelasticity have great clinical significance, such as the early diagnosis of keratoconus. In this work, an analysis method which utilized the elastic wave velocity, frequency and energy attenuation to assess the corneal viscoelasticity is presented. Using phase‐resolved optical coherence tomography, the spatial‐temporal displacement map is derived. The phase velocity dispersion curve and center frequency are obtained by
- Estimating Vocal Fold Stiffness: Using the Relationship between Subglottic Pressure and Fundamental Frequency of Phonation as an AnalogAbstract Objective The stiffness of the vocal folds is an important factor in voice production, yet clinically applicable measurements are still lacking. It has been demonstrated in an in vivo canine model that fundamental frequency (F0) increased linearly as subglottic pressure (Ps) increased, but with a lesser slope for higher levels of vocal fold tension. In this study, the relationship between F0 and Ps was investigated using the airflow
- Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based TranscriptomicsGlycerol is considered as a promising substrate for biotechnological applications and the non-conventional yeast Yarrowia lipolytica has been used extensively for the valorization of this compound. Contrary to S. cerevisiae, Y. lipolytica seems to prefer glycerol over glucose and it has been reported previously that the presence of glycerol can suppress the consumption of glucose in co-substrate fermentations. Based on these observations, we hypo
- Assessing by Modeling the Consequences of Increased Recombination in Recurrent Selection of Oryza sativa and Brassica rapaMeiotic recombination generates genetic diversity but in most species the number of crossovers per meiosis is limited. Previous modeling studies showed that increasing recombination can enhance response to selection. However, such studies did not assume a specific method of modifying recombination. Our objective was to test whether two methods used to increase recombination in plants could increase genetic gain in a population undergoing recurren
- MicroRNA-219a-5p suppresses intestinal inflammation through inhibiting Th1/Th17-mediated immune responses in inflammatory bowel diseaseMucosal Immunology, Published online: 18 October 2019; doi:10.1038/s41385-019-0216-7MicroRNA-219a-5p suppresses intestinal inflammation through inhibiting Th1/Th17-mediated immune responses in inflammatory bowel disease
- Epithelial RABGEF1 deficiency promotes intestinal inflammation by dysregulating intrinsic MYD88-dependent innate signalingMucosal Immunology, Published online: 18 October 2019; doi:10.1038/s41385-019-0211-zEpithelial RABGEF1 deficiency promotes intestinal inflammation by dysregulating intrinsic MYD88-dependent innate signaling
- Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell responseMucosal Immunology, Published online: 18 October 2019; doi:10.1038/s41385-019-0212-yInterleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response
- Translation, Validity, and Reliability of the Persian Version of the Aging Voice IndexThe Aging Voice Index (AVI) was developed to study quality of life in older adults with voice disorders. The purpose of this study was to translate the original English version of the AVI to Persian version of Aging Voice Index (P-AVI) and validate the P-AVI for the Persian-speaking older adults with voice disorders.
- [ASAP] Transition from Ferromagnetic Semiconductor to Ferromagnetic Metal with Enhanced Curie Temperature in Cr<sub>2</sub>Ge<sub>2</sub>Te<sub>6</sub> via Organic Ion IntercalationJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b06929
- [ASAP] Isotopic-Perturbation NMR Study of Hydrogen-Bond Symmetry in Solution: Temperature Dependence and Comparison of OHO and ODO Hydrogen BondsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08492
- [ASAP] Tuning the Molecular and Cationic Affinity in a Series of Multifunctional Metal–Organic Frameworks Based on Dodecanuclear Zn(II) Carboxylate WheelsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08322
- [ASAP] Separation of Monochlorotoluene Isomers by Nonporous Adaptive Crystals of Perethylated Pillar[5]arene and Pillar[6]areneJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b09988
- Trapping, dome puncture, and direct suction decompression in conjunction with assistant superficial temporal artery- middle cerebral artery bypass to clip giant internal carotid artery bifurcation aneurysmTrapping, dome puncture, and direct suction decompression in conjunction with assistant superficial temporal artery- middle cerebral artery bypass to clip giant internal carotid artery bifurcation aneurysm Category: Article Type: Seiei Torazawa, Hideaki Ono, Tomohiro Inoue, Takeo Tanishima, Akira Tamura, Isamu SaitoDepartment of Neurosurgery, Fuji Brain Institute and Hospital, Fujino
- Lung adenocarcinoma presumed to be Pott’s disease in a 28-year-old patient: A case report and review of literatureLung adenocarcinoma presumed to be Pott’s disease in a 28-year-old patient: A case report and review of literature Category: Article Type: Remi A. Kessler, Jeremy Steinberger, Sabrina Chen, Rebecca Baron, John M. CaridiDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.Department of Medical Education, New York University School of Medicin
- Ultra-early surgery in complete cervical spinal cord injury improves neurological recovery: A single-center retrospective studyUltra-early surgery in complete cervical spinal cord injury improves neurological recovery: A single-center retrospective study Category: Article Type: Davide Nasi, Paolo Ruscelli, Maurizio Gladi, Fabrizio Mancini, Maurizio Iacoangeli, Mauro DobranDepartment of Neurosurgery, Umberto I General Hospital, Marche Polytechnic University, Ancona, Italy.Department of Emergency Surgery, Umbe
- Chiari malformation and types of basilar invagination with/without syringomyeliaChiari malformation and types of basilar invagination with/without syringomyelia Category: Article Type: Ítalo Teles de Oliveira Filho, Paulo Cesar Romero, Emílio Afonso França Fontoura, Ricardo Vieira BotelhoProgram in Health Sciences-IAMSPE; Department of Neurosurgery, Hospital Mandaqui, Brazil.Department of Neurosurgery, Hospital Mandaqui, Brazil.Program in Health Sciences-IAMSPE;
- Holospinal epidural abscess in elderly patient: A case presentation and reviewHolospinal epidural abscess in elderly patient: A case presentation and review Category: Article Type: Ioannis D. Siasios, Aggeliki Fotiadou, Kostas Fountas, Vassilios DimopoulosDepartment of Neurosurgery, Papageorgiou Hospital, Thessaloniki, Greece,Department of Neurology, University Hospital of Alexandroupolis, Alexandroupolis, Greece,Department of Neurosurgery, University Hospital
- Parafalcine subdural empyema: The unresolved controversy over the need for surgical treatmentParafalcine subdural empyema: The unresolved controversy over the need for surgical treatment Category: Article Type: Ruth Prieto, Celia OrtegaDepartment of Neurosurgery, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.DOI:10.25259/SNI_392_2019Copyright: © 2019 Surgical Neurology International This is an open-access article distributed under the terms of the Creative
- A direct comparison of prophylactic low-molecular-weight heparin versus unfractionated heparin in neurosurgery: A meta-analysisA direct comparison of prophylactic low-molecular-weight heparin versus unfractionated heparin in neurosurgery: A meta-analysis Category: Article Type: Mohamed Macki, Mohamed Fakih, Sharath Kumar Anand, Raviteja Suryadevara, Jaafar Elmenini, Victor ChangDepartment of Neurosurgery, Henry Ford Hospital, Detroit, Michigan, USA.DOI:10.25259/SNI_428_2019Copyright: © 2019 Surgical Neurolog
- Thrombotic Hemangioma With Organizing/Anastomosing Features: Expanding the Spectrum of: GNA: -mutated Hemangiomas With a Predilection for the Skin of the Lower Abdominal RegionsIn this study, we aimed to present the clinicopathologic and molecular features of a distinct group of hemangioma with GNA mutations that exhibited prominent thrombosis and organization changes with florid intravascular endothelial cell proliferation that we provisionally termed “thrombotic hemangioma with organizing/anastomosing features.” Twenty-six cases were included. No sex predilection was seen (male:female=13:13). Patients’ age ranged from
- Immunohistochemistry for PRAME in the Distinction of Nodal Nevi From Metastatic MelanomaThe distinction of metastatic melanoma from melanocytic nevi in lymph nodes can on occasion be difficult. As diffuse immunohistochemical (IHC) PRAME (PReferentially expressed Antigen in MElanoma) expression is detected in the majority of primary and metastatic melanomas, but rarely in nevi, we reasoned that PRAME could be a useful adjunct marker for the diagnosis of melanocytes in lymph nodes. In this study, we examined 45 nodal melanocytic depos
- Contingent Convergence: The ability to detect convergent genomic evolution is dependent on population size and migration [NEW RESULTS]Outlier scans, in which the genome is scanned for signatures of selection, have become a prominent tool in studies of local adaptation, and more recently studies of genetic convergence in natural populations. However, such methods have the potential to be confounded by features of demographic history, such as population size and migration, which are considerably varied across natural populations. In this study, we use forward-simulations to inves
- Adapting the engine to the fuel: mutator populations can reduce the mutational load by reorganizing their genome structureMutators are common in bacterial populations, both in natural isolates and in the lab. The fate of these lineages, which mutation rate is increased up to 100 ×, has long been studied using population genetics ...
- Geographic isolation and climatic variability contribute to genetic differentiation in fragmented populations of the long-lived subalpine conifer Pinus cembra L. in the western AlpsGenetic processes shape the modern-day distribution of genetic variation within and between populations and can provide important insights into the underlying mechanisms of evolution. The resulting genetic var...
- Recording Obligatory Cortical Auditory Evoked Potentials in Infants: Quantitative Information on Feasibility and Parent AcceptabilityObjectives: With the advent of newborn hearing screening and early intervention, there is a growing interest in using supra-threshold obligatory cortical auditory evoked potentials (CAEPs) to complement established pediatric clinical test procedures. The aim of this study was to assess the feasibility, and parent acceptability, of recording infant CAEPs. Design: Typically developing infants (n = 104) who had passed newborn hearing screeni
- Minimal and Mild Hearing Loss in Children: Association with Auditory Perception, Cognition, and Communication ProblemsObjectives: “Minimal” and “mild” hearing loss are the most common but least understood forms of hearing loss in children. Children with better ear hearing level as low as 30 dB HL have a global language impairment and, according to the World Health Organization, a “disabling level of hearing loss.” We examined in a population of 6- to 11-year-olds how hearing level ≤40.0 dB HL (1 and 4 kHz pure-tone average, PTA, threshold) is related to audit
- Introduction: Rethinking the Archaeology of Capitalism: Coercion, Violence, and the Politics of AccumulationAbstract Long an analytical staple of historical archaeology, capitalism in recent years has found itself under renewed scrutiny, due in part to the repercussions of the 2008 global economic crisis. Questions about the failings of “free-market” self-regulation and the proliferation of predatory practices and value-manipulation instruments fostered discussions about what, in fact, the “true” nature of capitalism was, and whether
- Lifestyle is a threat to gut bacteria: Ötzi proves it, study showsThe evolution of dietary and hygienic habits in Western countries is associated with a decrease in the bacteria that help in digestion. These very bacteria were also found in the Iceman, who lived 5300 years ago, and are still present in non-Westernized populations in various parts of the world. The depletion of the microbiome may be associated with the increased prevalence, in Western countries, of complex conditions like allergies, autoimmune a
- [ASAP] Macrocyclization of a Class of Camptothecin Analogues into Tubular Supramolecular PolymersJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b09848
- [ASAP] Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic CascadeJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08510
- [ASAP] Re(tBu-bpy)(CO)<sub>3</sub>Cl Supported on Multi-Walled Carbon Nanotubes Selectively Reduces CO<sub>2</sub> in WaterJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08445
- Genes linked to sex ratio and male fertility in miceResearchers find genes that help maintain the 50-50 balance between male and female offspring in mice -- and that have major implications for male infertility.
- Enhanced mitochondrial autophagy (mitophagy) in oligodendrocytes might play a role in white matter pathology in schizophreniaPublication date: Available online 18 October 2019Source: Medical HypothesesAuthor(s): Hans-Gert Bernstein, Gerburg Keilhoff, Henrik Dobrowolny, Johann SteinerAbstractDisrupted white matter integrity is a typical feature of brain pathologic alterations in schizophrenia, which includes impaired myelination, decreased oligodendrocyte densities, distortion of their spatial distribution and deviations from normal oligodendrocyte cell morphology. Whil
- Mitochondrial dysfunction is the cause of one of the earliest changes seen on Magnetic Resonance Imaging in Charcot neuroarthopathy - oedema of the small muscles in the footPublication date: Available online 18 October 2019Source: Medical HypothesesAuthor(s): Margarita Lymbouris, Catherine Gooday, Ketan K. DhatariyaAbstractThe hypothesis laid out in this thesis states that the early changes seen on an MRI imaging in those with early Charcot neuroarthopathy may be due to mitochondrial dysfunction. In a Charcot foot, there is movement between bones. In an attempt to prevent this movement, the small muscles of the foot
- Increased cancer risk in polycystic ovary syndrome: an (un)sympathetic connection?Publication date: Available online 18 October 2019Source: Medical HypothesesAuthor(s): Boris Mravec, Miroslav TibenskyAbstractWomen with polycystic ovary syndrome (PCOS) have been shown to have a higher incidence of cancer. It is suggested that several factors, including hyperinsulinemia, dyslipidemia, raised estrogen levels, chronic inflammation, and reduced apoptosis are responsible for this association. However, in this paper we propose the hy
ΩτοΡινοΛαρυγγολόγος Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,
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Medicine by Alexandros G. Sfakianakis,
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