Aww … home for the holidays. Gatherings with family can create cherished memories. However, parents of children with feeding and swallowing disorders can find navigating holiday meals particularly difficult. As feeding and swallowing specialists, we speech-language pathologists can do much to serve our clients by offering tips to reduce food-related holiday stress. Parents often go on high alert when managing their child’s feeding and swallowing difficulties outside the home. In preparing to travel,...
Wed Oct 30, 2019 20:00
25-year-old Jenna Schardt underwent brain surgery — while awake — in Texas on Tuesday, and the procedure was livestreamed on Facebook. Doctors with the Methodist Dallas Medical Center performed the surgery to remove a mass of tangled blood vessels in Schardt’s brain that had impaired her speech and caused seizures. At the beginning of the operation, Schardt was put under anesthesia so doctors could cut into her skull. Once they reached her brain, Schardt was woken up so she could speak and answer...
Wed Oct 30, 2019 15:29
Presents overview of a study in North Carolina that found black women and rural women are more likely to lose their job or receive a pay cut after they've been diagnosed with cancer. Adjusting for socioeconomic factors, researchers still found disparities between black women and white women, calling on local governments to implement policies addressing these inequalities. (Source: News stories via the Rural Assistance Center)MedWorm Message: If you are looking to buy something in the January Sales...
Wed Oct 30, 2019 06:00
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Carolina Gon çalves Oliveira, Isolda Romero-Canelon, Monize M. Silva, James Coverdale, Pedro Ivo da Silva Maia, Alzir A Batista, Silvia Castelli, Alessandro Desideri, Peter J Sadler, Victor Marcelo Marcelo Deflon New palladium complexes with thiosemicarbazonate ligands derived from pyrene exhibit potent antiproliferative activity against A2780 and cisplatin-resistant A2780Cis human ovarian cancer cells, which is dependent...
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Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC07491K, CommunicationFang He, Ze-Yu Ye, Li-Dong Zhao, Bin-Cheng Yin, Bang-Ce Ye Exosomes, as an important subgroup of extracellular vesicles, are naturally released by numerous cell types, including both normal and cancer cells. They play an important role in intercellular communication and... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
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Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.9b00420 (Source: Chemical Research in Toxicology)
Wed Oct 30, 2019 05:00
Even though pancreatic ductal adenocarcinoma (PDAC) is associated with fibrotic stroma, the molecular pathways regulating the formation of cancer associated fibroblasts (CAFs) are not well elucidated. An epigenomic analysis of patient-derived andde-novo generated CAFs demonstrated widespread loss of cytosine methylation that was associated with overexpression of various inflammatory transcripts includingCXCR4. Co-culture of neoplastic cells with CAFs led to increased invasiveness that was abrogated...
Wed Oct 30, 2019 01:00
Because almost all studies of treatments for hepatorenal syndrome (HRS) are flawed, one cannot be recommended over another, a systematic review and meta-analysis concludes.Reuters Health Information (Source: Medscape Critical Care Headlines)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 22:29
How good is artificial intelligence in decision-making? Not bad according to findings from a pilot study that was recently presented at the American College of Surgeons Clinical Congress 2019. Findings from the study show AI in the form of a machine-learned algorithm correctly triaged the vast majority of postoperative patients to the intensive care unit in its first proof-of-concept application in a university hospital setting. As it stands now surgical teams typically rely on clinical judgment...
Wed Oct 30, 2019 18:00
NHS England and Improvement has provided details of shares of the £25m fund for improving hospices and palliative care. (Source: NHS Networks)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 00:00
. (Source: International Journal of Speech-Language Pathology)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 00:00
Journal of Palliative Medicine, Ahead of Print. (Source: Journal of Palliative Medicine)
Wed Oct 30, 2019 00:00
Journal of Palliative Medicine, Ahead of Print. (Source: Journal of Palliative Medicine)
Tue Oct 29, 2019 00:00
CONCLUSIONS: Increasing the capacity of a remote hospital to provide palliative care allowed more patients to die closer to home and decreased inappropriate aeromedical retrievals. An increased in-hospital mortality rate should not be misinterpreted as reflecting suboptimal care if palliative intent, patients' wishes and non-clinical risk factors have not been ascertained. This article is protected by copyright. All rights reserved. PMID: 31659827 [PubMed - as supplied by publisher] (Source:...
Tue Oct 29, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1302-1303, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1471-1472, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1483-1484, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1306-1307, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1297-1297, November 2019. (Source: Journal of Palliative Medicine)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1477-1477, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1298-1299, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1304-1305, November 2019. (Source: Journal of Palliative Medicine)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1300-1300, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1468-1470, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1475-1475, November 2019. (Source: Journal of Palliative Medicine)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1473-1474, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1476-1476, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1482-1482, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
Journal of Palliative Medicine,Volume 22, Issue 11, Page 1301-1301, November 2019. (Source: Journal of Palliative Medicine)
Fri Oct 25, 2019 00:00
CONCLUSIONS Upregulation of lncRNA-XIST was associated with cisplatin resistance in NSCLC by downregulating miRNA-144-3p in H460/DDP and A549/DDP cells, a murine A549/DDP tumor xenograft, and human tumor tissues from patients with cisplatin-resistant NSCLC. PMID: 31659146 [PubMed - in process] (Source: Medical Science Monitor)
Wed Oct 30, 2019 23:24
ConclusionsIn summary,pTuneos provides the state-of-the-art one-stop and user-friendly solution for prioritizing SNV-based candidate neoepitopes, which could help to advance research on next-generation cancer immunotherapies and personalized cancer vaccines.pTuneos is available athttps://github.com/bm2-lab/pTuneos, with a Docker version for quick deployment athttps://cloud.docker.com/u/bm2lab/repository/docker/bm2lab/ptuneos. (Source: Genome Medicine)MedWorm Message: If you are looking to buy something...
Wed Oct 30, 2019 00:00
DiscussionThis systematic review will aim to identify the postoperative period in which patients undergoing major pelvic surgery for malignancy are at further increased risk of VTE as a result of their surgery and the optimum duration of heparin VTE prophylaxis with heparin to reduce this risk. Determining this will allow evidence-based recommendations to be made for the optimum duration of heparin VTE prophylaxis post major pelvic surgery for malignancy, leading to improved standards of care that...
Wed Oct 30, 2019 00:00
FINDINGSResearchers at theUCLA Jonsson Comprehensive Cancer Center andDavid Geffen School of Medicine at UCLA have identified a new biomarker that could indicate how likely someone is to respond to treatment for lung cancer. In a test using mice, the scientists found that the level of activity of the mitochondria in lung tumor cells could potentially predict who would respond favorably to a type of drug called a complex I inhibitor, which targets mitochondrial function — and that the mitochondria...
Wed Oct 30, 2019 20:02
Risk reduced by more than 30 percent for high yogurt consumption and highest quintile of fiber intake (Source: Pulmonary Medicine News - Doctors Lounge)
Wed Oct 30, 2019 18:00
Report shows decrease in age - adjusted death rates, increase in age - adjusted death rate from overdose (Source: Pulmonary Medicine News - Doctors Lounge)
Wed Oct 30, 2019 18:00
Boost is part of technology roll-out Related items fromOnMedica UK cancer survival improved, but lags behind similar nations NHS must improve access to screening to save lives Call for NHS England to ‘think again’ on limiting treatment GP gatekeepers linked to reduced patient satisfaction Special scan may curb need for first biopsy in 1 in 4 men with prostate cancer (Source: OnMedica Latest News)
Wed Oct 30, 2019 00:00
Disaster-related disruption in healthcare to blame Related items fromOnMedica Measuring up: how does the UK compare internationally on cancer survival? Global cancer burden set to soar It ’s the end of the world as we know it, and I feel fine A child under 15 dies every five seconds around the world More non-smokers dying from lung cancer (Source: OnMedica Latest News)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all...
Wed Oct 30, 2019 00:00
Study finds the switch could also reduce drug costs Related items fromOnMedica Developers should factor pollution into plans Lung experts call for ‘national plan for lung cancer’ Health Outcome Framework may include measure on loneliness Prioritise and fund prevention to save lives and NHS, warn doctors It ’s the end of the world as we know it, and I feel fine (Source: OnMedica Latest News)
Wed Oct 30, 2019 00:00
James Peyer, formerly of Apollo Ventures and now at the larger Kronos BioVentures, has a range of interesting views on the new and growing longevity biotechnology industry. Apollo Ventures was one of the earlier longevity-focused funds to emerge from the comparatively small community of scientists, patient advocates, and investors enthusiastic to accelerate progress towards the treatment of aging as a medical condition. The presentation here was given earlier this year at the Ending Age-Related Diseases...
Wed Oct 30, 2019 20:07
Today on Health in 2 Point 00… hold on, where’s Jess? On Episode 99, I do a reverse takeover with Priyanka Kashyap and Sophie Park at Bayer’s office in Berlin. Priyanka tells us about what Bayer G4A is doing these days with the 5 startups in their Advance Track: Blackford Analysis in radiology; Carepay and RelianceHMO improving affordability and access for patients in Africa; NeuroTracker, which is in the neuro space but is working with the oncology team at Bayer; and Prevencio, a diagnostic solution...
Wed Oct 30, 2019 16:01
Conditions: Sensorineural Hearing Loss, Bilateral; Cochlear Hearing Loss Interventions: Device: Hearing aids programmed conventionally.; Device: Hearing aids programmed with compression activated. Sponsors: Manchester University NHS Foundation Trust; University of Manchester Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 17:00
King's College London scientists were able to reduce patients' sensitivity to the nut using immunotherapy pills, but they could not get rid of the allergy altogether. (Source: the Mail online | Health)
Wed Oct 30, 2019 01:21
Condition: Metastatic or Non-driver Gene Mutation Non-small Cell Lung Cancer Intervention: Drug: Sintilimab Combined With Docetaxel Monotherapy Sponsor: Yongchang Zhang Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Metastatic Breast Cancer Interventions: Drug: Vinorelbine; Drug: Gemcitabine; Drug: Carboplatin Sponsor: Shandong Cancer Hospital and Institute Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Lung Cancer Interventions: Drug: Erlotinib HCl 150 mg; Drug: Tarceva® Sponsor: Quadras Scientific Solutions Completed (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Prostate Cancer Interventions: Behavioral: Soccer; Behavioral: mHealth Sponsor: Emory University Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Colorectal Cancer; Angiogenesis Intervention: Procedure: COLORECTAL CANCER SURGERY Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Colorectal Cancer Interventions: Diagnostic Test: mt-sDNA 2.0 screening test; Diagnostic Test: FIT test; Procedure: Colonoscopy Sponsor: Exact Sciences Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Lynch Syndrome; Colorectal Cancer; Breast Cancer; Ovarian Cancer; Family Characteristics; Genetic Predisposition Interventions: Other: online cancer risk assessment; Other: Usual care Sponsors: Kaiser Permanente; Patient-Centered Outcomes Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Insomnia, Secondary; Breast Cancer Female; Chemotherapy Interventions: Procedure: Electroacupuncture (EA) and Auricular Acupressure (AA); Procedure: Sham Electroacupuncture (SE) and Sham Auricular Acupressure (SA) Sponsor: The University of Hong Kong Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Breast Cancer; Necrosis Intervention: Diagnostic Test: ICG microangiography Sponsor: University of Wisconsin, Madison Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Biochemically Recurrent Prostate Carcinoma; Prostate Adenocarcinoma; PSA Failure; PSA Progression Interventions: Combination Product: Carbon C 11 Choline; Procedure: Computed Tomography; Other: Gallium Ga 68-labeled PSMA-11; Procedure: Positron Emission Tomography Sponsors: Mayo Clinic; National Cancer Institute (NCI) Recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social...
Wed Oct 30, 2019 17:00
Conditions: Non Small Cell Lung Cancer; Neoepitopes; Neoantigens; Immunotherapy; Next Generation Sequencing (NGS); Personalized Neoantigen Cancer Vaccine Intervention: Biological: Collection of biopsy (FFPE), blood (PBMC) and stool Sponsors: Ardigen; Małopolskie Centre of Entrepreneurship Recruiting (Source: ClinicalTrials.gov)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK....
Wed Oct 30, 2019 17:00
Condition: Colorectal Cancer Intervention: Other: Blood Sample Collection Sponsor: Exact Sciences Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Microsatellite-stable Colorectal Cancer Interventions: Drug: Standard of Care - mFOLFOX6; Drug: E1 - mFOLFOX and durvalumab; Drug: E2 - mFOLFOX6, durvalumab and oleclumab; Drug: E3 - mFOLFOX6, durvalumab and monalizumab Sponsor: MedImmune LLC Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Advanced Non Small Cell Lung Cancer Intervention: Drug: treprilumab combination with platinum-containing dual-drug chemotherapy Sponsor: Yongchang Zhang Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Acute Lymphoblastic Leukemia; Lymphoblastic Leukemia Interventions: Drug: IM JZP-458; Drug: IV JZP-458 Sponsors: Jazz Pharmaceuticals; Children's Oncology Group (COG) Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Non-cutaneous Squamous Cell Carcinoma of Head and Neck Interventions: Drug: ALKS 4230; Drug: Pembrolizumab Sponsors: Alkermes, Inc.; Immune Oncology Network Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Wed Oct 30, 2019 17:00
Conditions: Head and Neck Cancer; Pain; Dysfunction Intervention: Other: Manual therapy Sponsor: Universidad de Granada Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Urinary Bladder Neoplasm Intervention: Other: Evaluation of muscle mass and muscle function Sponsors: Rigshospitalet, Denmark; Roche Pharma AG; Merck Sharp & Dohme Corp.; Beckett Foundation; Onkologisk Forskningsfond Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Hepatocellular Carcinoma; Liver Cancer; Cholangiocarcinoma Intervention: Sponsor: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Ductal Breast Carcinoma In Situ; HER2/Neu Positive Interventions: Biological: Granulocyte-Macrophage Colony-Stimulating Factor; Biological: Multi-epitope HER2 Peptide Vaccine H2NVAC; Procedure: Therapeutic Conventional Surgery Sponsors: Mayo Clinic; National Cancer Institute (NCI) Recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Condition: Colorectal Cancer Intervention: Dietary Supplement: Phenylalanine intake Sponsor: University of Alberta Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 17:00
Condition: Nasopharyngeal Carcinoma Interventions: Radiation: Carbon-ion radiotherapy; Drug: Camrelizumab; Drug: Apatinib Sponsor: Shanghai Proton and Heavy Ion Center Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Glioblastoma, IDH-Mutant; Recurrent Glioblastoma Interventions: Biological: Ipilimumab; Biological: Nivolumab Sponsor: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Wed Oct 30, 2019 17:00
Conditions: Advanced Solid Tumor; Malignant Solid Tumor Intervention: Drug: DS-7300a Sponsor: Daiichi Sankyo Co., Ltd. Recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Wed Oct 30, 2019 17:00
Conditions: Breast Cancer; Breast Neoplasms; Triple Negative Breast Cancer; HER2-positive Breast Cancer Intervention: Drug: Parsaclisib Sponsors: UNC Lineberger Comprehensive Cancer Center; Incyte Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Tue Oct 29, 2019 17:00
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