Background. Previous studies have demonstrated pivotal roles of disintegrin and metalloproteinase 10 (ADAM10) in the pathogenesis of sepsis. MicroRNA- (miR-) 23b has emerged as an anti-inflammatory factor that prevents multiple autoimmune diseases. However, the underlying mechanisms of miR-23b in the regulation of ADAM10 and sepsis remain uncharacterized. Methods. The expression levels of ADAM10 and miR-23b were detected by quantitative RT-PCR and western blot analysis. Cytokine production and THP-1...
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Tue Oct 29, 2019 20:37
Abstract Purpose The aim of this study is to investigate the changes in the volume of individual thalamic nuclei in patients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS). Methods We enrolled 80 TLE patients with HS and 40 healthy controls. All of the subjects underwent 3D T1-weighted imaging. The hippocampus subfields and thalamic nuclei...
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What a boycott that never happened can reveal about blame, consumer psychology and the free-market system The Conversation US
Wed Oct 30, 2019 20:59
Abstract Background Low molecular weight heparin (LMWH) is an anticoagulant that has recently been found benefit in the acute exacerbation stage of chronic obstructive pulmonary disease (COPD). But its efficacy is controversial. The objective of this paper is to compare the harm/benefit of LMWH combined with conventional therapy versus single conventional therapy in the acute exacerbation stage of COPD. ...
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Toxins, Vol. 11, Pages 632: Improved Accuracy of Saxitoxin Measurement Using an Optimized Enzyme-Linked Immunosorbent Assay Toxins doi: 10.3390/toxins11110632 Authors: Jennifer R. McCall W. Christopher Holland Devon M. Keeler D. Ransom Hardison R. Wayne Litaker Paralytic shellfish poisoning (PSP) is precipitated by a family of toxins produced by harmful algae, which are consumed by filter-feeding and commercially popular shellfish. The toxins, including saxitoxin, neosaxitoxin,...
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Plants, Vol. 8, Pages 466: Growth Characteristics of Adenophora triphylla var. japonica Hara Seedlings as Affected by Growing Medium Plants doi: 10.3390/plants8110466 Authors: Hye Ri Lee Hyeon Min Kim Hyeon Woo Jeong Gam Gon Kim Chae In Na Myung Min Oh Seung Jae Hwang Adenophora triphylla var. japonica Hara is a highly valued medicinal plant that is used to treat or prevent bronchitis, cough, cancer, and obesity. However, there has been no study on the production of...
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Agronomy, Vol. 9, Pages 702: Melatonin Stimulates Activities and Expression Level of Antioxidant Enzymes and Preserves Functionality of Photosynthetic Apparatus in Hickory Plants (Carya cathayensis Sarg.) under PEG-Promoted Drought Agronomy doi: 10.3390/agronomy9110702 Authors: Junfeng Wang Juanjuan Chen Anket Sharma Shenchen Tao Bingsong Zheng Marco Landi Huwei Yuan Daoliang Yan Nowadays, drought is one of the major abiotic factors which negatively affects growth...
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IJMS, Vol. 20, Pages 5423: The Role of MicroRNAs in Diabetes-Related Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms20215423 Authors: Mirza Muhammad Fahd Qadir Dagmar Klein Silvia Álvarez-Cubela Juan Domínguez-Bendala Ricardo Luis Pastori Cellular stress, combined with dysfunctional, inadequate mitochondrial phosphorylation, produces an excessive amount of reactive oxygen species (ROS) and an increased level of ROS in cells, which leads to oxidation...
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Arts, Vol. 8, Pages 146: Circulating Regalia and Lakȟóta Survivance, c. 1900 Arts doi: 10.3390/arts8040146 Authors: Emily C. Burns This essay offers object biographies of two examples of Lakȟóta beaded regalia that traveled with Wild West performers to France in 1889 and in 1911, respectively, as exemplars of Gerald Vizenor’s concept of survivance. By examining the production of the objects by women artists within the Lakȟóta community and visually analyzing...
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Materials, Vol. 12, Pages 3573: Robust Memristor Networks for Neuromorphic Computation Applications Materials doi: 10.3390/ma12213573 Authors: Dániel Hajtó Ádám Rák György Cserey One of the main obstacles for memristors to become commonly used in electrical engineering and in the field of artificial intelligence is the unreliability of physical implementations. A non-uniform range of resistance, low mass-production yield and high fault probability during operation are disadvantages...
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IJMS, Vol. 20, Pages 5422: Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs International Journal of Molecular Sciences doi: 10.3390/ijms20215422 Authors: Michele d’Angelo Vanessa Castelli Maria Grazia Tupone Mariano Catanesi Andrea Antonosante Reyes Dominguez-Benot Rodolfo Ippoliti Anna Maria Cimini Elisabetta Benedetti Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the...
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Sensors, Vol. 19, Pages 4728: Chaotic Signatures Exhibited by Plasmonic Effects in Au Nanoparticles with Cells Sensors doi: 10.3390/s19214728 Authors: Hilario Martines-Arano Blanca Estela García-Pérez Mónica Araceli Vidales-Hurtado Martín Trejo-Valdez Luis Héctor Hernández-Gómez Carlos Torres-Torres The evolution of the optical absorptive effects exhibited by plasmonic nanoparticles was systematically analyzed by electronic signals modulated by a Rössler attractor...
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Particles, Vol. 2, Pages 457-480: Dissipation Triggers Dynamical Two-Stream Instability Particles doi: 10.3390/particles2040028 Authors: Nils Andersson Andreas Schmitt Two coupled, interpenetrating fluids suffer instabilities beyond certain critical counterflows. For ideal fluids, an energetic instability occurs at the point where a sound mode inverts its direction due to the counterflow, while dynamical instabilities only occur at larger relative velocities. Here, we discuss two...
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Materials, Vol. 12, Pages 3571: A Combination of Keyhole GTAW with a Trapezoidal Interlayer: A New Insight into Armour Steel Welding Materials doi: 10.3390/ma12213571 Authors: Zhenyu Fei Zengxi Pan Dominic Cuiuri Huijun Li Azdiar A. Gazder The ballistic performance of armour steel welds using austenitic filler materials is poor on account of the disparity in the mechanical properties of the weld and base metals. Consequently, a novel Keyhole Gas Tungsten Arc Welding process...
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Remote Sensing, Vol. 11, Pages 2557: Correcting Position Error in Precipitation Data Using Image Morphing Remote Sensing doi: 10.3390/rs11212557 Authors: Camille Le Coz Arnold Heemink Martin Verlaan Marie-claire ten Veldhuis Nick van de Giesen Rainfall estimates based on satellite data are subject to errors in the position of the rainfall events in addition to errors in their intensity. This is especially true for localized rainfall events such as the convective rainstorms...
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Polymers, Vol. 11, Pages 1781: Self-Assembly Supramolecular Systems Based on Guanidinium Salts Modified Hyperbranched Polyamidoamine and Cationic Acrylamide Copolymers Polymers doi: 10.3390/polym11111781 Authors: Qi Wu Shaohua Gou Yumei Fei Xiaoyan Yang Mengyu Liu Jinglun Huang Herein, novel hyperbranched polyamidoamine guanidinium salts (GS-h-PAMAM) and two cationic acrylamide copolymers P(AM-DAC-ABSM) and P(AM-DAC-AMTU) were successfully prepared. Then, self-assembly...
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Nutrients, Vol. 11, Pages 2606: Combined Buckwheat d-Fagomine and Fish Omega-3 PUFAs Stabilize the Populations of Gut Prevotella and Bacteroides While Reducing Weight Gain in Rats Nutrients doi: 10.3390/nu11112606 Authors: Mercè Hereu Sara Ramos-Romero Roser Marín-Valls Susana Amézqueta Bernat Miralles-Pérez Marta Romeu Lucía Méndez Isabel Medina Josep Lluís Torres Some functional food components may help maintain homeostasis by promoting balanced gut microbiota....
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Metals, Vol. 9, Pages 1175: Mechanical Behavior and Microstructure Evolution of a Ti-15Mo/TiB Titanium–Matrix Composite during Hot Deformation Metals doi: 10.3390/met9111175 Authors: Sergey Zherebtsov Maxim Ozerov Margarita Klimova Dmitry Moskovskikh Nikita Stepanov Gennady Salishchev A Ti-15Mo/TiB titanium–matrix composite (TMC) was produced by spark plasma sintering at 1400 °C under a load of 40 MPa for 15 min using a Ti-14.25(wt.)%Mo-5(wt.)%TiB2 powder...
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Materials, Vol. 12, Pages 3572: Strong Modulations of Optical Reflectance in Tapered Core–Shell Nanowires Materials doi: 10.3390/ma12213572 Authors: Francesco Floris Lucia Fornasari Vittorio Bellani Andrea Marini Francesco Banfi Franco Marabelli Fabio Beltram Daniele Ercolani Sergio Battiato Lucia Sorba Francesco Rossella Random assemblies of vertically aligned core–shell GaAs–AlGaAs nanowires displayed an optical response dominated by...
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Energies, Vol. 12, Pages 4157: Single-Layer Transmitter Array Coil Pattern Evaluation toward a Uniform Vertical Magnetic Field Distribution Energies doi: 10.3390/en12214157 Authors: Win-Jet Luo C. Bambang Dwi Kuncoro Pratikto Yean-Der Kuan A uniform magnetic field distribution is a critical aspect in the transmitter array coil design process for achieving a homogenous vertical magnetic field distribution. The free position and orientation features can thus be implemented in...
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Materials, Vol. 12, Pages 3576: Evaluation of Targeted Delivery to the Brain Using Magnetic Immunoliposomes and Magnetic Force Materials doi: 10.3390/ma12213576 Authors: Louiza Bohn Thomsen Thomas Linemann Svend Birkelund Gitte Abildgaard Tarp Torben Moos Magnetic nanoparticles have great prospects for drug delivery purposes, as they can be designed with various surface coatings and conjugated with drugs and targeting moieties. They also have a unique potential for precise...
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IJERPH, Vol. 16, Pages 4224: Romantic Love and Reproductive Hormones in Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214224 Authors: Piotr Sorokowski Agnieszka Żelaźniewicz Judyta Nowak Agata Groyecka Magdalena Kaleta Weronika Lech Sylwia Samorek Katarzyna Stachowska Klaudia Bocian Aleksandra Pulcer Agnieszka Sorokowska Marta Kowal Katarzyna Pisanski Increased reproductive success is among the most commonly...
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Abstract Purpose The purpose of this study was to evaluate potential differences in volumes of areas of osteolysis caused by medication-related osteonecrosis of the jaw (MRONJ) between the upper and lower jaw. We aim to analyze the clinical relevance of volumetric measurement of osteolytic lesions for surgical planning of MRONJ patients. Methods Sixty-seven...
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Γράφει η Κάλλια Θ. ΓιαννιτσοπούλουΚλινική διαιτολόγος – διατροφολόγος, ΜSc, MBA, SRDhttp://social.somaygies.gr/1x8b5g2 Η ωμοφαγία είναι ένα υποσύνολο της φυτοφαγίας. Όπως και στη φυτοφαγία, έτσι και στην ωμοφαγία αποκλείουμε όλα τα τρόφιμα ζωικής προέλευσης. Στην ωμοφαγία όμως προστίθεται η έννοια της ακατέργαστης τροφής, η οποία υπαγορεύει ότι τα τρόφιμα πρέπει να τρώγονται εντελώς ακατέργαστα ή θερμαινόμενα σε θερμοκρασίες κάτω των 40-48 βαθμών Κελσίου. Μία ωμοφαγική διατροφή είναι γενικά...
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Abstract Purpose Preoperative prediction of transsphenoidal surgical (TSS) response is important for determining individual treatment strategies for acromegaly. There is currently no accurate predictive model for TSS response for acromegaly. The current study sought to develop and validate machine learning (ML)-based models for preoperative prediction of TSS response for acromegaly. ...
Wed Oct 30, 2019 02:00
Abstract Objectives To explore healthcare providers’ perspectives of disrespect and abuse in maternity care and the impact on women’s health and well-being. Methods Qualitative interpretive approach using in-depth semi-structured interviews with sixteen healthcare providers in two public health facilities in Nigeria. Interviews were audio-recorded,...
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Abstract Purpose Acute ischemic stroke is one of the most causes of death all over the world. Onset to treatment time is critical in stroke diagnosis and treatment. Considering the time consumption and high price of MR imaging, CT perfusion (CTP) imaging is strongly recommended for acute stroke. However, too much CT radiation during CTP imaging may increase the risk of health problems. How to reduce CT radiation dose in CT perfusion imaging...
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Objectives. To quantify radiation exposure during pediatric cardiac catheterizations performed by multiple operators on a new imaging platform, the Artis Q.zen (Siemens Healthcare, Forchheim, Germany), and to compare these data to contemporary benchmark values. Background. The Artis Q.zen has been shown to achieve significant radiation reduction during select types of pediatric cardiac catheterizations in small single-center studies. No large multicenter study exists quantifying patient dose exposure...
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Deformation is a comprehensive reflection of the structural state of a concrete dam, and research on prediction models for concrete dam deformation provides the basis for safety monitoring and early warning strategies. This paper focuses on practical problems such as multicollinearity among factors; the subjectivity of factor selection; robustness, externality, generalization, and integrity deficiencies; and the unsoundness of evaluation systems for prediction models. Based on rough set (RS) theory...
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Far-infrared ray (FIR) therapy has been reported to exert beneficial effects on cardiovascular function by elevating endothelial nitric oxide synthesis (eNOS) activity and nitric oxide (NO) production. Tetrahydrobiopterin (BH4) is a key determinant of eNOS-dependent NO synthesis in vascular endothelial cells. However, whether BH4 synthesis is associated with the effects of FIR on eNOS/NO production has not yet been investigated. In this study, we investigated the effects of FIR on BH4-dependent eNOS/NO...
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Objective. Traditional Chinese medicine (TCM) therapies have been widely used for the treatment of androgenetic alopecia (AGA) for thousands of years. We conducted a meta-analysis to evaluate the curative efficacy and safety of TCM for treating AGA. Methods. Randomized controlled trials (RCTs) of TCM for the treatment of AGA through March 2019 were systematically identified in 4 English databases, namely, PubMed, Cochrane Library, EMBASE, and Web of Science, and 4 Chinese databases, namely, Sino-Med,...
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Cudraxanthone D (CD), derived from the root bark of Cudrania tricuspidata, is a natural xanthone compound. However, the biological activity of CD in terms of human metabolism has been barely reported to date. Autophagy is known as a self-degradation process related to cancer cell viability and metastasis. Herein, we investigated the effects of CD on human oral squamous cell carcinoma (OSCC) metastatic related cell phenotype. We confirmed that CD effectively decreased proliferation and viability in...
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We present a case of a 54-year-old man with primary angiitis of the central nervous system (PACNS) who was initially admitted to a psychiatric clinic with a diagnosis of delirium. We discuss the difficulty in establishing the diagnosis of PACNS and provide the reader with some recommendations on how to promptly and correctly diagnose this disease in order to avoid potentially lethal outcomes.
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The vibration effect generated during tunnel excavation can influence or damage adjacent tunnels. Studying and controlling the blasting vibration effect has important theoretical and practical significance, especially for new tunnels. This paper takes the tunnel project of Gao Jiu Lu-Jia Hua Cross Tunnel in Chongqing as the research background and assesses the blasting vibration influence in the up-down cross-tunnel. Onsite monitoring and numerical simulation were used to analyze peak particle velocity...
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In order to improve the detection rate of the traditional single-shot multibox detection algorithm in small object detection, a feature-enhanced fusion SSD object detection algorithm based on the pyramid network is proposed. Firstly, the selected multiscale feature layer is merged with the scale-invariant convolutional layer through the feature pyramid network structure; at the same time, the multiscale feature map is separately converted into the channel number using the scale-invariant convolution...
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