Related ArticlesProtein Kinase Cα Mediates Recovery of Renal and Mitochondrial Functions Following Acute Injury. FEBS J. 2019 Oct 28;: Authors: Nowak G, Megyesi J Abstract Previously, we have shown that active PKCα promotes recovery of mitochondrial function after injury in vitro [24]. This study examined whether PKCα regulates recovery of mitochondrial and kidney functions after ischemia-induced acute injury (AKI) in vivo. Markers of kidney injury were...
Wed Oct 30, 2019 12:27
Related ArticlesEarly induction intensification with cladribine, cytarabine, and mitoxantrone (CLAM) in AML patients treated with the DAC induction regimen: a prospective, non-randomized, phase II study of the Polish Adult Leukemia Group (PALG). Leuk Lymphoma. 2019 Oct 29;:1-16 Authors: Pluta A, Robak T, Brzozowski K, Stepka K, Wawrzyniak E, Krawczynska A, Czemerska M, Szmigielska-Kaplon A, Grzybowska-Izydorczyk O, Nowicki M, Stelmach P, Kuydowicz M, Gromek T, Hus M,...
Wed Oct 30, 2019 14:24
Related ArticlesKi67 expression and localization of T-cells after neoadjuvant therapies as reliable predictive markers in rectal cancer. Cancer Sci. 2019 Oct 29;: Authors: Imaizumi K, Suzuki T, Kojima M, Shimomura M, Sakuyama N, Tsukada Y, Sasaki T, Nishizawa Y, Taketomi A, Ito M, Nakatsura T Abstract Chemoradiotherapy (CRT) is the standard neoadjuvant therapy for locally advanced rectal cancer (RC). However, neoadjuvant chemotherapy (NAC) also shows...
Wed Oct 30, 2019 14:23
Related ArticlesDe Ritis ratio as a significant prognostic factor of international normalized ratio ≥4 in the initial 10 days of warfarin therapy. Biomark Med. 2019 Oct 29;: Authors: Cao Y, Chen G, Li H, Liu Y, Tao Z, Li L, Chen W, Xu Y, Chen X Abstract Aim: To assess the relationship between the De Ritis ratio on admission and warfarin sensitivity in the initial 10 days of anticoagulation therapy. Methods: We retrospectively reviewed data from 906 patients...
Wed Oct 30, 2019 14:27
Related ArticlesAssociation of Cyr61-cysteine-rich protein 61 and short-term mortality in patients with acute heart failure and coronary heart disease. Biomark Med. 2019 Oct 29;: Authors: Liu C, Cao Y, He X, Zhang C, Liu J, Zhang L, Wu D, Zhuang X, Xue R, Huang H, Jiang J, Dong B, Sun Y, Dong Y, Zhao J Abstract Aim: The CCN1/CYR61, Cyr61-cysteine-rich protein 61, exerts critical functions in myocardial ischemic injury. We sought to investigate the prognostic...
Wed Oct 30, 2019 14:27
Related ArticlesEarly NT-proBNP and MR-proANP associated with QoL 1 year after acutely decompensated heart failure: secondary analysis from the MOLITOR trial. Biomark Med. 2019 Oct 29;: Authors: Zelenak C, Chavanon ML, Tahirovic E, Trippel TD, Tscholl V, Stroux A, Veskovic J, Apostolovic S, Obradovic D, Zdravkovic M, Loncar G, Störk S, Herrmann-Lingen C, Düngen HD Abstract Aim: Heart failure negatively impacts quality of life (QoL), which in turn contributes...
Wed Oct 30, 2019 14:27
Related ArticlesA novel tablet-based approach for hearing screening of the pediatric population, 516-patient study. Laryngoscope. 2019 Oct 29;: Authors: Xiao L, Zou B, Gao L, Weng M, Lando M, Smith AE, Barber W, Yao H Abstract OBJECTIVE: Assess a tablet hearing game as a screening instrument for pediatric hearing loss. METHODS: All children age 3 to 13 presenting to the ENT clinic of a tertiary hospital clinic over a 3-month period were eligible...
Wed Oct 30, 2019 14:28
Related ArticlesTransoral neck surgery prevents attentional bias towards the neck compared to open neck surgery. Laryngoscope. 2019 Oct 29;: Authors: Liao D, Ishii LE, Chen LW, Chen J, Juarez M, Darrach HM, Kumar AR, Russell JO, Tufano RP, Ishii M Abstract OBJECTIVE: Measure attentional distraction of neck scars after open neck surgery compared to transoral endoscopic thyroidectomy via a vestibular approach (TOETVA) or transoral endoscopic parathyroidectomy...
Wed Oct 30, 2019 14:28
Yaseen M Arabi, Sami J Alsolamy, Abdulaziz Al-DawoodSaudi Critical Care Journal 2019 3(3):95-98
Wed Oct 30, 2019 00:00
Hani M S Lababidi, Abrar Alajlani, Abdullah Alasmari, Wajed Alshammeri, Wejdan Khalid Suwayyid, Ahmed A BahnassySaudi Critical Care Journal 2019 3(3):99-103 Background: Many cancer patients need admission to intensive care unit (ICU). It is important to identify patients who will benefit most from ICU care. Objective: The current study aimed to identify the clinical features associated with outcomes and factors predicting ICU mortality of cancer patients at a tertiary care hospital in Riyadh, Saudi...
Wed Oct 30, 2019 00:00
Y Vishnu Rohit, Raghu K, M ShabnumSaudi Critical Care Journal 2019 3(3):104-108 Background: Critical ill will be accessed by sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation. Circulating ischemia-modified albumin is generated under ischemic and oxidative conditions and it reflects the disease severity. Aims and Objectives: The objective of this study is to compare the sensitivity and rapidness of Ischemia Modified Albumin as a biomarker with that of...
Wed Oct 30, 2019 00:00
Publication date: Available online 30 October 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Alexandra F. Santos, Louisa K. James, Matthew Kwok, Richard T. McKendry, Katherine Anagnostou, Andrew T. Clark, Gideon Lack
Wed Oct 30, 2019 12:21
Related ArticlesHistory of allergic rhinitis and risk of asthma; a systematic review and meta-analysis. World Allergy Organ J. 2019 Oct;12(10):100069 Authors: Tohidinik HR, Mallah N, Takkouche B Abstract Background: Allergic rhinitis has been suspected to be a risk factor for asthma in several studies but this association is not firmly established. The objective of this study was to synthesize the evidence of the association between allergic rhinitis...
Wed Oct 30, 2019 13:20
Abstract Background Although frailty is known to be an important prognostic factor in heart failure (HF), HF risk‐adjustment models do not incorporate frailty measures and the interplay between frailty, age, and pharmacotherapy is unclear. Objectives To explore the relationships between frailty, pharmacotherapy, and outcomes in heart failure (HF). Methods Retrospective cohort study of all adults in Alberta, Canada hospitalized for the first time for HF between 2004 and 2016. Frailty...
Tue Oct 29, 2019 20:19
Retrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres.
Related ArticlesRetrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres. World J Gastroenterol. 2019 Oct 21;25(39):5991-6005 Authors: Frizziero M, Wang X, Chakrabarty B, Childs A, Luong TV, Walter T, Khan MS, Morgan M, Christian A, Elshafie M, Shah T, Minicozzi A, Mansoor W, Meyer T, Lamarca A, Hubner RA, Valle JW, McNamara MG Abstract BACKGROUND: Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is...
Wed Oct 30, 2019 13:25
Related ArticlesPlasma levels of polychlorinated biphenyls (PCB) and the risk of soft tissue sarcoma. Med Lav. 2019 Oct 29;110(5):342-352 Authors: Guercio V, Donato F, Pelucchi C, Verga F, Passini V, Galeone C, Negri E, Garzaro G, Boffetta P, La Vecchia C, Tavani A, Pira E Abstract BACKGROUND: Soft tissue sarcoma (STS) is a heterogeneous group of rare neoplasms whose aetiology is largely unknown. Dioxin and dioxin-like compounds, including 2,3,7,8-tetrachlorodibenzo-p-dioxin...
Wed Oct 30, 2019 13:25
Related ArticlesAneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. Oncogene. 2019 Oct 28;: Authors: Njeru SN, Kraus J, Meena JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler HA, Günes C, Rudolph KL Abstract Aneuploidy can instigate tumorigenesis. However, mutations in genes that control chromosome...
Wed Oct 30, 2019 12:17
Related ArticlesAgminated atypical melanocytic nevus associated with Langerhans cell histiocytosis. An Bras Dermatol. 2019;94(4):455-457 Authors: Carreño-Gayosso EA, Hernández-Peralta SL, Guevara-Gutiérrez E, Solís-Ledezma G Abstract Agminated nevus refers to the presence of multiple nevi grouped in a circumscribed skin area; it is rarely reported in the literature. This report presents the case of a 10-year-old female patient with a history of Langerhans...
Wed Oct 30, 2019 12:17
Related ArticlesSolitary Large Intraoral Neurilemmoma of the Maxillary Vestibule: A Rare Case with Brief Literature Review. J Contemp Dent Pract. 2019 Jul 01;20(7):847-850 Authors: Sholapurkar A, Milosevic MP, Mallela VR, Pai KM Abstract AIM: This current report aimed at presenting a rare case of a large solitary intraoral neurilemmoma of the buccal vestibule followed by a brief review of literature of neurilemmoma published between 1997 and 2017. ...
Wed Oct 30, 2019 12:17
Related Articles[Clinical and prognostic analysis of single-center multidisciplinary treatment for rhabdomyosarcoma in children]. Zhonghua Er Ke Za Zhi. 2019 Oct 02;57(10):767-773 Authors: Xu N, Duan C, Jin M, Zhang DW, Su Y, Yu T, He LJ, Fu LB, Zeng Q, Wang HM, Zhang WP, Ni X, Ma XL Abstract Objective: To summarize the clinical characteristics, treatment response and prognostic factors of rhabdomyosarcoma (RMS) in children. Methods: The clinical characteristics...
Wed Oct 30, 2019 12:17
Related ArticlesPrimary Leiomyosarcoma of the Mandible: Posttreatment Malocclusion Treated with an Overpartial Mandibular Resection Prosthesis. Int J Prosthodont. 2019 Sep/Oct;32(5):448-450 Authors: Ahmed ZU, Matros E, Huryn JM, Nelson J, Allen RJ, Patel S, Disa J, Rosen EB Abstract Leiomyosarcoma is a rare malignant condition occurring in the maxillofacial region in which the mandible may be affected. Management of this tumor in the mandible may include...
Wed Oct 30, 2019 12:17
Related ArticlesOncologic emergencies. Vnitr Lek. 2019;65(6):405-415 Authors: Karvuni T, Matějovič M Abstract Oncologic emergencies and life-threatening cancer-related and treatment-related complications are the net effect of gradually increasing incidence of malignant diseases, improvement of therapeutic options and survival of oncologic patients. These complications are relatively specific for such population of patients and they are quite rare within...
Wed Oct 30, 2019 12:17
Related Articles[Laryngeal Recurrent Respiratory Papillomatosis: Current Aspects on Diagnosis and Therapy]. Laryngorhinootologie. 2019 Aug;98(8):577-587 Authors: Langer C, Wittekindt C, Wolf G Abstract Recurrent Respiratory Papillomatosis (RRP) is a rare infectious disease of the upper aerodigestive tract caused by human papillomavirus (HPV). Virus subtypes 6 and 11 are found in most of the papillomas, type 11 is associated with a severe course. There...
Wed Oct 30, 2019 12:17
Related Articles[Subglottic pathologies]. Laryngorhinootologie. 2019 Jul;98(7):461-472 Authors: Heyduck A, Pickhard A, Brosch S, Hoffmann TK, Reiter R Abstract Subglottic pathologies are rare and show a clinical unspecific appearance i. e. through tissue increase around the cricoid or the cranial trachea. Typical symptoms are hoarseness, an overstimulated coughing, a globus laryngeus feeling as well as dyspnea or a stridor. Differential diagnosis include...
Wed Oct 30, 2019 12:17
Related ArticlesOral squamous cell carcinoma arising in a patient with Werner syndrome. Int J Oral Maxillofac Surg. 2019 Nov;48(11):1394-1397 Authors: Kuribayashi N, Uchida D, Hamasaki Y, Kawamata H Abstract Werner syndrome (WS) is an autosomal recessive disorder characterized by physical signs and symptoms, including premature aging and scleroderma-like skin changes. The gene responsible for WS is the WRN gene. A significant proportion of WS-related...
Wed Oct 30, 2019 12:17
Related ArticlesOral Hairy Leukoplakia in Patients With No Evidence of Immunosuppression: A Case Series and Review of the Literature. J Can Dent Assoc. 2018 05;84:i4 Authors: Darling MR, Alkhasawneh M, Mascarenhas W, Chirila A, Copete M Abstract OBJECTIVES: Oral hairy leukoplakia (OHL) is caused by Epstein-Barr virus (EBV) and is often associated with HIV and other immunosuppressive conditions. It is rare in HIV-negative patients, but has been reported...
Wed Oct 30, 2019 12:17
Related ArticlesIsolated angiokeratomas of the tongue: A rare entity. Indian J Dent Res. 2019 Mar-Apr;30(2):322-326 Authors: Hamid R, Chalkoo AH, Singh I, Wani S, Bilal S Abstract Angiokeratomas consist of ectasias of dermal capillaries associated with an acanthotic and hyperkeratotic overlying epidermis. These dark red-to-purple, papular vascular anomalies can vary considerably in size, depth, and location. It is a skin disorder that rarely involves...
Wed Oct 30, 2019 12:17
Related ArticlesTranszygomatic, transcondylar excision of the sarcoma of infratemporal fossa. Indian J Dent Res. 2019 Mar-Apr;30(2):318-321 Authors: Balaji SM, Balaji P Abstract Malignant peripheral nerve sheath tumor (MPNST) is a rare pathologic lesion in a patient with solitary neurofibroma. A 32-year-old man presented with a firm and slightly tender mass in the right infratemporal region involving the right preauricular and temporomandibular joint...
Wed Oct 30, 2019 12:17
Related ArticlesAutomated brain histology classification using machine learning. J Clin Neurosci. 2019 Aug;66:239-245 Authors: Ker J, Bai Y, Lee HY, Rao J, Wang L Abstract Brain and breast tumors cause significant morbidity and mortality worldwide. Accurate and expedient histological diagnosis of patients' tumor specimens is required for subsequent treatment and prognostication. Currently, histology slides are visually inspected by trained pathologists,...
Wed Oct 30, 2019 12:17
Related ArticlesParaganglioma of the spine: A twenty-years clinical experience of a high volume tumor center. J Clin Neurosci. 2019 Aug;66:7-11 Authors: Pipola V, Boriani S, Bandiera S, Righi A, Barbanti Bròdano G, Terzi S, Ghermandi R, Tedesco G, Evangelisti G, Girolami M, Gasbarrini A Abstract Paragangliomas (PGs) are rare tumours with a reported estimated annual incidence of up to 3 per million. Spinal involvement may possible with spinal metastasis...
Wed Oct 30, 2019 12:17
Related ArticlesHead and neck pleomorphic myxoid liposarcoma in a child with Li-Fraumeni syndrome. Int J Pediatr Otorhinolaryngol. 2019 Aug;123:191-194 Authors: Francom CR, Leoniak SM, Lovell MA, Herrmann BW Abstract INTRODUCTION: Pleomorphic myxoid liposarcoma is a rare and aggressive cancer seen in the pediatric population that has been previously associated with hereditable cancer disorders like Li Fraumeni syndrome. We present a case report and...
Wed Oct 30, 2019 12:17
Related ArticlesPartial empty sella in a woman with cerebral venous sinus thrombosis: A rare presentation of polycythaemia rubra vera. J Clin Neurosci. 2019 Aug;66:275-277 Authors: Lennon MJ, Neuen DR, Suttie JJ Abstract We report the case of a 59 year old woman who presented with a six week history of worsening bifrontal headache. On CT brain the only abnormal finding was a partially empty sella potentially indicative of increased intracranial pressure....
Wed Oct 30, 2019 12:17
Related ArticlesBrain abscess complicating ischemic embolic stroke in a patient with cardiac papillary fibroelastoma - Case report and literature review. J Clin Neurosci. 2019 Aug;66:277-279 Authors: Boukobza M, Nahmani S, Deschamps L, Laissy JP Abstract A 72-year-old man without obvious risk factors initially presented with acute ischemic stroke and fever, without concomitant infection. Broad spectrum antibiotic therapy was initiated. Transthoracic...
Wed Oct 30, 2019 12:17
Related ArticlesA new strategy for enhancing antitumor immune response using dendritic cells loaded with chemo-resistant cancer stem-like cells in experimental mice model. Mol Immunol. 2019 07;111:106-117 Authors: El-Ashmawy NE, El-Zamarany EA, Salem ML, Khedr EG, Ibrahim AO Abstract BACKGROUND AND AIM: Cancer stem cells (CSCs) are rare cell population present in the tumor bulk that are thought to be the reason for treatment failure following chemotherapy...
Wed Oct 30, 2019 12:17
Related ArticlesVery large Ameloblastic Fibroma with Calcifying Odontogenic Cyst in an 8-year-old child. Histological and immunohistochemical characterisation. Eur J Paediatr Dent. 2019 Mar;20(1):19-22 Authors: Cutilli T, Coletti G, Fatayer MW, Caruso S, Tecco S, Gatto R, Leocata P Abstract BACKGROUND: Ameloblastic fibroma (AF) is an uncommon odontogenic tumour that may present an aggressive behaviour and may have potential for malignant transformation....
Wed Oct 30, 2019 12:17
Related ArticlesMelanotic neuroectodermal tumour of infancy: Refining the surgical approach. Int J Oral Maxillofac Surg. 2019 Oct;48(10):1307-1312 Authors: Rickart AJ, Drummond-Hay V, Suchak A, Sadiq Z, Sebire NJ, Slater O, Mills C Abstract Melanotic neuroectodermal tumours of infancy (MNTI) are particularly rare and although predominantly benign, are infiltrative and locally aggressive. Presenting in the first year of life, prompt diagnosis and effective...
Wed Oct 30, 2019 12:17
Related ArticlesEmbolization of Ruptured Renal Angiomyolipoma in Puerpera. Rev Bras Ginecol Obstet. 2019 Mar;41(3):199-202 Authors: Góes Junior AMO, Jeha SAH, de Oliveira CP, Santos DASD Abstract Angiomyolipomas (AMLs) are rare benign tumors derived from mesenchymal tissue and composed of varying degrees of adipose tissue, muscle and blood vessels. Renal AMLs (RAMLs) are the result of a sporadic event, and, in most of cases, the diagnosis is usually...
Wed Oct 30, 2019 12:17
Related ArticlesManagement of accessory parotid gland tumours: 32-year experience from a single institution and review of the literature. Int J Oral Maxillofac Surg. 2019 Sep;48(9):1145-1152 Authors: Luksic I, Mamic M, Suton P Abstract Accessory parotid gland tumours (APGTs) are very rare. Regarding their anatomical location, an adequate surgical approach is necessary to provide safe resection and satisfactory postoperative results. The aims of this...
Wed Oct 30, 2019 12:17
Related ArticlesPregnancy-Preserving Laparoscopic Treatment of Acute Hemoperitoneum Following Lutein Cyst Rupture in Early Gestation. Z Geburtshilfe Neonatol. 2019 Apr;223(2):109-112 Authors: Watrowski R Abstract Acute hemoperitoneum (AHP) in early gestation is commonly treated via laparotomy. A ruptured corpus luteum (CL) cyst is a rare cause of AHP in pregnancy. This case report describes a 33-year-old, hemodynamically stable G2/P1 who presented at...
Wed Oct 30, 2019 12:17
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