5 Psychological Factors of Brand Awareness and Trust [Infographic] Social Media Today
Law firm brings psychologist on site as mental health wanes The Australian Financial Review
UCLA expert available to discuss the stress, emotional trauma and psychological impact of the California wildfires Newswise
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Abstract Purpose Muscle fat content of the rotator cuff increases after a tear. In the healthy rotator cuff, the influence of age, body mass index (BMI) and critical shoulder angle (CSA) on muscle fat content is unknown. The primary aim was to correlate muscle fat content with age, BMI and CSA. The secondary aims were (1) to correlate muscle fat content in the entire muscle and slice Y (most lateral sagittal slice with scapular spine)...
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Clinical Trials, Ahead of Print. Background/aims:Clinical trial oversight is central to the safety of participants and production of robust data. The United Kingdom Medical Research Council originally set out an oversight structure comprising three committees in 1998. The first committee, led by the trial team, is hands-on with trial conduct/operations (‘Trial Management Group’) and essential. The second committee (Data Monitoring Committee), usually completely independent of the trial, reviews accumulating...
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Abstract Background A falls prevention programme has been initiated in balneotherapy at Balaruc-les-Bains. Aims To determine the health profiles of subjects who are at risk of falls, over 65 years of age and attending balneotherapy. Methods Questionnaires were used to evaluate...
Abstract Background Polypharmacy increases the risk of potentially inappropriate prescribing. STOPP&START criteria identify a group of drugs representing inappropriate medication and a group of drugs representing potential prescribing omissions. Aims To evaluate the appropriateness of prescription of antiplatelet and anticoagulant drugs in a sample of...
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In 2017, a total of 19% of all new HIV infections in the United States and nearly half of infections globally were in cisgender (nontransgender) women. Women of childbearing potential shoulder a disproportionate burden, which raises further concerns about perinatal transmission of the virus.…
An altered intestinal microbiome has been implicated in the pathogenesis of many disorders. Fecal microbiota transplantation (FMT) refers to the administration of intestinal microbes from a healthy donor into a recipient with the intent of modifying the recipient’s intestinal microbiome. FMT is an…
To the Editor: Fecal microbiota transplantation (FMT) has emerged as a treatment for recurrent Clostridioides difficile infection. Procurement of safe donors for FMT and for biologically sourced microbiome therapies is complex, particularly given recent concerns over antibiotic-resistant bacteria…
The term "dysbiosis" usually refers to a change in the human microbiome from a healthy pattern toward a pattern associated with disease. Although the term is increasingly being used, the definition, not surprisingly, is vague. Yet dysbiosis has become an area of great interest in medical science.…
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Abstract Based on the idea of a “Community of Human Destiny,” the Chinese government proposed the “Belt and Road” initiative, and clearly proposed to promote green development and strengthen ecological environmental protection. However, a considerable number of countries are resource-rich economies with serious market misallocations. Using the stochastic frontier analysis (SFA) combined with the directional distance function (DDF) framework, this paper measures the green total...
Abstract Insecticidal applications may result to morphological deformations upon exposed insects or their offspring production. In the present study, we tested whether pirimiphos-methyl can induce deformities to wings of progeny production of the invasive khapra beetle, Trogoderma granarium (Coleoptera: Dermestidae) when its parental female adults have been treated with this organophosphorus active ingredient. For that purpose, we analysed both elytra and hindwings of both sexes...
Abstract The present paper investigates the effects of hydropower energy consumption on economic growth and CO2 emissions in the BRICS countries, spanning the period 1990–2016. To achieve this aim of the study, we employ the panel autoregressive distributed lag (ARDL) model and panel quantile regression (PQR) estimations. The results confirm that hydropower energy consumption has a positive association with economic growth in the long run and short run, and negative association...
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IntroductionPostoperative pulmonary complications (PPCs), strongly associated with higher mortality risk, can develop in up to 58% of patients undergoing abdominal surgery. More and more evidence shows that the use of a lung-protective ventilation strategy has a lung protection effect in patients undergoing abdominal surgery, however, the role of positive end-expiratory pressure (PEEP) during the intraoperative period in preventing PPCs for laparoscopic surgery is not clearly defined. Methods and...
ObjectivesTo engage children and young people with conditions that impair learning, their parents/carers and the health, education, social work and third sector professionals to identify and prioritise research questions for learning difficulties. DesignProspective surveys and consensus meeting guided by methods advocated by the James Lind Alliance. SettingScotland. MethodsThe Priority Setting Partnership came together through discussion and collaboration between the University of Edinburgh, Scottish...
IntroductionOral emergency contraception (EC) can prevent unintended pregnancy but it is important to start a regular method of contraception. Women in the UK usually access EC from a pharmacy but then need a subsequent appointment with a general practitioner or a sexual and reproductive health (SRH) service to access regular contraception. Unintended pregnancies can occur during this time. Methods and analysisBridge-It is a pragmatic cluster randomised cohort cross-over trial designed to determine...
IntroductionFibromyalgia (FM) is a common debilitating condition with limited therapeutic options. Medications have low efficacy and are often associated with adverse effects. Given that FM is associated with a defective endogenous pain control system and central sensitisation, combining interventions such as transcranial direct current stimulation (tDCS) and aerobic exercise (AE) to modulate pain-processing circuits may enhance pain control. Methods and analysisA prospective, randomised (1:1:1:1),...
BackgroundFetal alcohol spectrum disorders (FASD) are a global health concern. To further understand FASD in adulthood is a major public health interest. ObjectiveTo describe the clinical characteristics of young adults with FASD adopted from orphanages to a socially more favourable and stable rearing environment as children. DesignProspective observational cohort study SettingWestern Sweden ParticipantsA population-based cohort of 37 adoptees diagnosed with FASD in childhood. Outcome measuresAssessment...
BackgroundGestational age and birth weight are strong predictors of infant morbidity and mortality. Understanding spatial variation can inform policies to reduce health inequalities. We examined small-area variation in gestational age and birth weight in Switzerland. MethodsAll singleton live births recorded in the Swiss Live Birth Register 2011 to 2014 were eligible. We deterministically linked the Live Birth Register with census and survey data to create data sets including neonatal and pregnancy-related...
IntroductionThe optimal management of patent ductus arteriosus (PDA) remains contentious. The medications used to treat PDA are often non-steroidal anti-inflammatory drugs, which are associated with a number of unwanted adverse effects. Paracetamol is a medication with an excellent safety profile in infants and has been suggested as a safe alternative medication in situations where other medications have failed or are contraindicated. There are limited data on the use of early, intravenous paracetamol...
ObjectivesThis study aimed to investigate Australian pharmacists’ views about their role in physician-assisted suicide (PAS), their ethical and legal concerns and overall thoughts about PAS in pharmacy. DesignSemistructured interviews of pharmacists incorporating a previously validated vignette and thematic analysis. SettingAustralia (face to face or phone call). Participants40 Australian Health Practitioner Regulation Agency registered pharmacists, majority women (65%) with varied experiences...
ObjectivesTo evaluate seroprevalence against Bordetella pertussis in Tuscany, a large Italian region, from 1992 to 2005 and from 2013 to 2016. DesignSeroepidemiological study. Participants1812 serum samples collected in Tuscany from subjects older than 12 years from 1992 to 2005 and from 2013 to 2016. Outcome measuresSpecific antibody levels were determined by means of standard commercial ELISA using a dual cut-off of 50 and 125 IU/mL as markers of past and recent infection/vaccination, respectively....
ObjectiveTo analyse the secular trends in mean value and distribution of weight, height and weight for height in children under 7 years in developed regions in China. DesignFive repeated cross-sectional surveys were conducted using the same methods at the same sites during 1975–2015. SettingNine cities in northern, central and southern regions of China. PopulationHealthy children under 7 years; the sample sizes were 94 496 in 1975, 79 177 in 1985, 79 152 in 1995, 69 760 in 2005 and 83 583 in 2015....
ObjectiveAnalyses of the impact of a body of clinical trial reports subject to research misconduct have been few. Our objective was to examine the impact on clinically relevant research of a group of researchers’ trial reports (‘affected trial reports’) affected by research misconduct, and whether identification of misconduct invoked a reappraisal. DesignIn 2016, we used five databases and search engines to identify ‘citing publications’, that is, guidelines, systematic and other reviews, and clinical...
IntroductionPatient-reported outcome (PRO) measures are increasingly developed with multisite, representative patient populations so that they can serve as a primary endpoint in clinical trials and longitudinal studies. Creating multisite infrastructure during PRO measure development can facilitate future comparative effectiveness trials. We describe our protocol to simultaneously develop a PRO measure and create a collaborative of tertiary care centres to address the needs of patients with unilateral...
IntroductionHaemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%. Early diagnosis and specific immune suppressive treatment are mandatory to avoid fatal outcome, but the diagnostic criteria (HLH-2004) are adopted from paediatric HLH and have not been validated in adults. Experimental studies suggest biomarkers to sufficiently diagnose HLH. However, biomarkers...
ObjectivesQuantify non-attendance at sexual health clinics and explore help-seeking strategies for genitourinary symptoms. DesignSequential mixed methods using survey data and semistructured interviews. SettingGeneral population in Britain. Participants1403 participants (1182 women) from Britain’s Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3; undertaken 2010–2012), aged 16–44 years who experienced specific genitourinary symptoms (past 4 weeks), of whom 27 (16 women) who reported...
ObjectiveIn Guinea-Bissau, West Africa, we observed that having a smallpox vaccination scar was associated with lower HIV-1 prevalence, more strongly for women than men. If this represents a causal effect, the female/male HIV-1 prevalence ratio would increase for birth cohorts no longer receiving smallpox vaccination due to the phase-out of this vaccine. DesignAn ecological design using HIV surveys and information about smallpox vaccination coverage. SettingUrban and rural Guinea-Bissau. ParticipantsParticipants...
IntroductionAntibiotic resistance (AR) is among the most pressing global health challenges. Fluoroquinolones are a clinically important group of antibiotics that have wide applicability in both humans and animals. While many drivers of AR are known, the impact of medicine quality on AR remains largely unknown. The aim of this review is to systematically evaluate the evidence of the impact of in vitro subinhibitory antibiotic exposure, a major tenet of substandard antibiotics, on the development of...
ObjectivePrevious studies in cardiac patients noted that early patient follow-up with general practitioners (GPs) after hospital discharge was associated with reduced rates of hospital readmissions. We aimed to identify patient, clinical and hospital factors that may influence GP follow-up of patients discharged from a tertiary cardiology unit. DesignSingle centre retrospective cohort study. SettingAustralian metropolitan tertiary hospital cardiology unit. Participants1079 patients discharged...
ObjectiveTo assess Chilean medical and midwifery students’ attitudes and willingness to become trained to provide abortion care, shortly after abortion was decriminalised in 2017. DesignWe fielded a cross-sectional, web-based survey of medical and midwifery students. We used generalised estimating equations to assess differences by type of university and degree sought. SettingWe recruited students from a combination of seven secular, religiously-affiliated, public and private universities that...
IntroductionCongenital heart disease (CHD) is the most frequent congenital malformation. With recent advances in medical care, the majority of patients with CHD survive into adulthood. As a result, interest has shifted towards the neurodevelopmental outcome of these patients, and particularly towards the early detection and treatment of developmental problems. A variety of mild to moderate cognitive impairments as well as emotional and behavioural problems has been observed in this population. However,...
BackgroundWhite cell count (WCC) is a clinical marker of inflammation. Data are limited regarding the association of total and differential WCC with risk of mortality, and its role related with smoking and body mass index (BMI). MethodsA total of 14 433 participants (4150 men; 10 283 women; average age 47.3±11.8 years) from the Dutch European Prospective Investigation into Cancer and Nutrition-Netherlands cohort were included. The associations between prediagnostic total WCC and its subtypes and...
ObjectivesWe investigated the association of specific serum amino acids (AAs) with the odds of arsenic-induced skin lesions (AISL) and their ability to distinguish patients with AISL from people chronically exposed to arsenic. DesignCase–control study. SettingThree arsenic-exposed villages in Wuyuan County, Hetao Plain, Inner Mongolia, China were evaluated. ParticipantsAmong the 450 residents aged 18–79 years, who were chronically exposed to arsenic via drinking water, 56 were diagnosed as having...
IntroductionPeople with serious mental illness (SMI) and/or substance use disorders (SUDs) have an elevated risk of premature mortality compared with the general population. This has been attributed to higher rates of chronic illness among these individuals, but also to inequities in healthcare access and treatment. Integrated care has the potential to improve the health of people with SMI/SUDs. The aims of this scoping review are to: (1) identify empirical investigations of interventions designed...
IntroductionSubstantial delays in translating evidence to practice mean that many beneficial and vital advances in medical care are not being used in a timely manner. Traditional knowledge translation (KT) strategies have tended to target academics by disseminating findings in academic journals and at scientific conferences. Alternative strategies, such as theatre-based KT, appear to be effective at targeting broader audiences. The purpose of this scoping review is to collate and understand the current...
ObjectivesThe aim was to describe population-based incidence and emergency department-based prevalence and 1-year all-cause mortality of patients with new organ failure present at arrival. DesignThis was a population-based cohort study of all citizens in four municipalities (population of 230 000 adults). SettingEmergency department at Odense University Hospital, Denmark. ParticipantsWe included all adult patients who arrived from 1 April 2012 to 31 March 2015. Primary and secondary outcome measuresOrgan...
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