The buried pipelines and metallic structures in subway systems are subjected to electrochemical corrosion under the stray current interference. The corrosion current density determines the degree and the speed of stray current corrosion. A method combining electrochemical experiment with the machine learning algorithm was utilized in this research to study the corrosion current density under the coupling action of stray current and chloride ion. In this study, a quantum particle swarm optimization-neural...
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This paper focuses on the robust control of fractional-order economical chaotic system (FOECS) with parametric uncertainties and external disturbances. The dynamical behavior of FOECS is studied by numerical simulation, and circuit implementations of FOECS are also given. Based on fractional-order Lyapunov stability theorems, a robust adaptive controller, which can guarantee that all signals remain bounded and the tracking error tends to a small region, is designed. The proposed method can be used...
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This paper discusses the stability of semi-Markovian jump networked control system containing time-varying delay and actuator faults. The system dynamic is optimized while the network resource is saved by introducing an improved static event-triggered mechanism. For deriving a less conservative stability criterion, the Bessel–Legendre inequalities approach is employed to the stability analysis and plays a major role. By constructing the enhanced Lyapunov–Krasovskii functional (LKF) relevant to the...
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The neuromuscular disorders are diagnosed using electromyographic (EMG) signals. Machine learning algorithms are employed as a decision support system to diagnose neuromuscular disorders. This paper compares bagging and boosting ensemble learning methods to classify EMG signals automatically. Even though ensemble classifiers’ efficacy in relation to real-life issues has been presented in numerous studies, there are almost no studies which focus on the feasibility of bagging and boosting ensemble...
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Background. Focal hyperhidrosis mostly affects the axillae, hands, feet, and face. For the management, several techniques are used. The aim of this study was to investigate the effects of direct current administration on the hyperhidrosis disease severity scale (HDSS) in patients with axillary hyperhidrosis that have various HDSS scores. Design and Setting. Original article, University Hospital. Methods. Sixty patients with primary axillary hyperhidrosis were inquired about the HDSS scores and the...
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Objective. The present study aims at evaluating the beneficial effect of Nigella sativa (NS) oil mouth rinse in the management of chemotherapy- (CT-) induced oral mucositis (OM) in patients with acute myeloid leukemia (AML). Methods. Fifty-four AML patients were participated in this study and randomly allocated to either the test group or a control group. The patients of the test group received NS oil mouth rinse during 28-day CT, while the participants of the control group received a “magic mouthwash”...
Wed Oct 30, 2019 18:05
A refined liver cancer staging system and effective prognostic prediction can help clinicians make optimized treatment decisions, which is essential in our fight against cancer and for improving the unsatisfying survival rate of liver cancer globally. The prognosis of liver cancer is not only related to tumor status, it is also affected by the patients’ liver functions and the chosen treatment. Currently, several staging systems are being tested. Herein, we analyzed RNA-seq data from the TCGA database...
Wed Oct 30, 2019 17:05
Background. Upper partial fibulectomy has been preliminarily proved to have the efficacy for pain alleviation and improvement of function in patients with mild to moderate medial compartment knee osteoarthritis (KOA). However, the previous studies lack the control group with other treatments. The aim of this prospective, randomized controlled study is to compare the clinical and biomechanical effects between upper partial fibulectomy and drug conservative treatment on improvement of clinical pain,...
Wed Oct 30, 2019 17:05
Objective. The aim of this study was to evaluate the cytotoxic potential of a type of endodontic pin on L929 cell line according to the UNI EN ISO 10993/2009 rule. Methods. L929 cells were used for the assays; extracts were prepared from three different-diameter endodontic pins, made of epoxy resin and fiberglass matrix and from Reference Materials (ZDEC, ZDBC, and HDP films). MTS assay was performed after 24 h, 48 h, and 72 h of exposure of L929 cells to pin and Reference Material extracts, 5% phenol...
Wed Oct 30, 2019 17:05
Osteoarthritis (OA) is one of the major diseases leading to disability, and inflammation plays an important role in the pathogenesis of OA. However, inflammation of OA is multifactorial, chronic, and in low intensity, which makes drug-based immunotherapy difficult. Here, we have designed a novel method of exercise—static low angle squat (SLAS), which reduces the intra-articular inflammation of OA knee as well as strengthens the vastus medialis of quadriceps. A two-year follow-up trial of current...
Wed Oct 30, 2019 15:05
Purpose. Mean platelet volume (MPV) and platelet distribution width (PDW) have been used to reflect the platelet activity in clinics. We assessed initial serum MPV and PDW levels in colorectal cancer (CRC) patients, in predicting the development of sepsis in CRC patients postoperatively. Patients and Methods. This study included 220 patients diagnosed with CRC. 55 patients were stratified to one group that developed sepsis postoperatively, and 165 patients were stratified to the other group that...
Wed Oct 30, 2019 15:05
Protein-protein interactions (PPIs) can be conveniently represented as networks, allowing the use of graph theory for their study. Network topology studies may reveal patterns associated with specific organisms. Here, we propose a new methodology to denoise PPI networks and predict missing links solely based on the network topology, the organization measurement (OM) method. The OM methodology was applied in the denoising of the PPI networks of two Saccharomyces cerevisiae datasets (Yeast and CS2007)...
Wed Oct 30, 2019 15:05
There is a substantial use of pesticides within the agricultural industry of Chile, with neurotoxic effects through mechanisms of acetylcholinesterase inhibition. These pesticides result in deterioration in health, increasing the risk of diseases such as Parkinson’s and Alzheimer’s in highly exposed occupational population. To date, there are no brief assessment tools to monitor cognitive impairment in agricultural workers chronically exposed to these pesticides. Method. 234 agricultural workers...
Wed Oct 30, 2019 15:05
Takotsubo syndrome (TTS) is a recently identified cardiac disease, which is far from being completely known. The aims of this narrative review are to provide a better understanding of the pathophysiological features of TTS and to update clinical findings in order to improve the management of subjects affected by this syndrome (according to the most recent consensus papers issued by the international scientific societies). We based our search on the material obtained via PubMed up to April 2019. The...
Wed Oct 30, 2019 11:05
The present study was carried out to assess the contraceptive efficacy of sperm agglutinating factor (SAF) isolated from Serratia marcescens, in male Balb/c mice. Mice were administered via an intratesticular route with different concentrations of SAF, viz., 10, 50, 100, 200, or 400 µg, in the right testis only which served as a test while the left side served as control except otherwise stated. Mice were sacrificed on day 3, 7, 14, 21, 30, 45, 60, and 90 after administration, and results in terms...
Wed Oct 30, 2019 11:05
The biological function of human ovaries declines along with aging. To identify the underlying molecular changes during ovarian aging, pigs were used as model animals. Genome-wide DNA methylation and transcriptome-wide RNA expression analyses were performed via high-throughput sequencing of ovaries from young pigs (180 days, puberty stage of first ovulation) and old pigs (eight years, reproductive exhaustion stage). The results identified 422 different methylation regions between old and young pigs;...
Wed Oct 30, 2019 11:05
Purpose. The aim of this study was to understand the relationship between the findings of spectral-domain optical coherence tomography (SD-OCT) of previously reported animal models of retinitis pigmentosa (RP) associated with known genetic mutations and their background structural and functional changes. Methods. We reviewed previous publications reporting the SD-OCT findings of animal models of RP and summarized the characteristic findings of SD-OCT in nine different animal models (RCS–/–, RHO P23H,...
Wed Oct 30, 2019 11:05
Flavoproteins and their interacting proteins play important roles in mitochondrial electron transport, fatty acid degradation, and redox regulation. However, their clinical significance and function in esophageal squamous cell carcinoma (ESCC) are little known. Here, using survival analysis and machine learning, we mined 179 patient expression profiles with ESCC in GSE53625 from the Gene Expression Omnibus (GEO) database and constructed a signature consisting of two flavoprotein genes (GPD2 and PYROXD2)...
Wed Oct 30, 2019 11:05
Virulence-associated traits have frequently been studied in enterococci and are considered to contribute towards the pathogenicity of infections. In the present study, Enterococcus isolates were collected during diagnostic investigations from meat turkeys in Germany. Twenty-eight isolates of three different Enterococcus species were analyzed for five selected putative virulence traits to understand their potential role in the pathogenicity using the chicken embryo lethality assay. Ten E. faecalis,...
Wed Oct 30, 2019 11:05
IJMS, Vol. 20, Pages 5423: The Role of MicroRNAs in Diabetes-Related Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms20215423 Authors: Mirza Muhammad Fahd Qadir Dagmar Klein Silvia Álvarez-Cubela Juan Domínguez-Bendala Ricardo Luis Pastori Cellular stress, combined with dysfunctional, inadequate mitochondrial phosphorylation, produces an excessive amount of reactive oxygen species (ROS) and an increased level of ROS in cells, which leads to oxidation...
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Diroximel fumarate showed better GI tolerability compared with dimethyl fumarate in patients with relapsing forms of multiple sclerosis in the EVOLVE-MS-2 phase 3 study.FDA Approvals (Source: Medscape Allergy Headlines)
Wed Oct 30, 2019 17:08
Title: Antihistamines Linked to Delayed Care for Severe Allergic Reaction: StudyCategory: Health NewsCreated: 10/28/2019 12:00:00 AMLast Editorial Review: 10/29/2019 12:00:00 AM (Source: MedicineNet Allergies General)
Tue Oct 29, 2019 08:00
Abstract Subtotal deglovement injuries with delayed presentation give rise to the question: how to treat the mangled soft tissue to best keep the digit alive and functioning. We hereby present a case of a 59-year-old woman who was referred to our clinic 7 h after initial trauma from a peripheral hospital where an instant repositioning of a subtotal degloved skin envelop of her left middle finger had taken place with only minimal adhesion and circulation at the top of the finger...
Wed Oct 30, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01749F, PaperIshaan Maitra, Camilo Morais, Kassio Michell Gomes de Lima, Katherine Ashton, Ravindra Date, Francis L MartinDiagnostic tools for the detection of early-stage oesophageal adenocarcinoma (OAC) are urgently needed. Our aim was to develop an accurate and inexpensive method using biofluids (plasma, serum, saliva or urine)...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01869G, PaperSergiy Patskovsky, Mengjiao Qi, Michel MeunierIn the article we present the optical platform to investigate the dynamics of individual nanoparticle assisted pulsed laser optoporation of single living cells. Here plasmonic nanoparticles (NP) act as live...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01509D, PaperYehia Ibrahim, Ailin Li, Sandilya GarimellaProbing molecular properties in the gas phase requires the integration of complementary ion manipulation approaches such as ion mobility spectrometry. Structures for lossless ion manipulations (SLIM) has recently been developed...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Oct 30, 2019 02:00
Analyst, 2019, Advance ArticleDOI: 10.1039/C9AN01608B, PaperMiaomiao Hong, Yufen Chen, Yuping Zhang, Dongmei XuHg2+ was reversibly detected by a simple and wonderful rhodamine-based spectral sensor.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Oct 30, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01905G, PaperRoland Agoston, Md Abu Sayeed, Michael M W Jones, Martin Daly de Jonge, Anthony Peter O'MullaneElectrochemical water splitting to generate hydrogen has been identified as a possible solution to the storage of intermittent renewable energy. However there are still challenges remaining in the development of...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Oct 30, 2019 02:00
Biomedicines, Vol. 7, Pages 85: Cystatin from Filarial Parasites Suppress the Clinical Symptoms and Pathology of Experimentally Induced Colitis in Mice by Inducing T-Regulatory Cells, B1-Cells, and Alternatively Activated Macrophages Biomedicines doi: 10.3390/biomedicines7040085 Authors: Nalini Bisht Vishal Khatri Nikhil Chauhan Ramaswamy Kalyanasundaram Potential alternative therapeutic strategies for immune-mediated disorders are being increasingly recognized and are studied...
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Abstract Purpose To evaluate the role of diffusion kurtosis and diffusivity as potential imaging biomarkers to predict response to neoadjuvant chemoradiation therapy (CRT) from baseline staging magnetic resonance imaging (MRI) in locally advanced rectal cancer (LARC). Materials and methods This retrospective study included 45 consecutive patients...
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Abstract Purpose To analyze changes in MRI diagnostic accuracy in main rectal tumor (T) evaluation resulting from the use of diffusion-weighted imaging (DWI), according to the degree of experience of the radiologist. Methods This is a cross-sectional study of a database including one hundred 1.5 T MRI records (2011–2016) from patients with biopsy-proven...
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Abstract Evaluation of primary rectal cancer specimens places the pathologist in a unique position relative to peers, as it is one of the few specimens where the report influences not just patient outcomes but also the quality of the surgical technique itself. With ever-increasing data indicating that the completeness of the mesorectal excision and adequate resection margins are critical for reduced local recurrence rates and improved clinical outcome, the pathologist is faced...
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Abstract Combined PET/MRI is a proposed imaging modality for rectal cancer, leveraging the advantages of MRI and 18F-fluorodeoxyglucose PET. Rectal cancer PET/MRI protocols typically include dedicated pelvis bed positions utilizing small field-of-view T2-weighted imaging. For staging of the primary tumor, PET/MRI can help delineate the extent of tumor better as well as the extent of tumor beyond the muscularis propria. PET uptake may help characterize small lymph nodes, and the...
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Abstract There is a wide array of pathological lesions seen in the anorectal region with CT colonography (CTC), much of which is unique to this location. Many relatively common findings in the anorectal region are typically benign, but can be misinterpreted as malignant. There are also technique-related pitfalls that can impede accurate diagnosis of anorectal findings at CTC. Understanding common and uncommon lesions in the anorectal region as well as recognizing technical pitfalls...
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Abstract Purpose To assess preoperative short-course radiotherapy (SCR) tumor response in locally advanced rectal cancer (LARC) by means of Standardized Index of Shape (SIS) by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), apparent diffusion coefficient (ADC), intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) parameters derived from diffusion-weighted MRI (DW-MRI). ...
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Abstract Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/mm2 (b1000) versus ultrahigh b = 2000 s/mm2 (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between...
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Abstract Around 1/3 of patients of locally advanced carcinoma thyroid present with tracheal infiltration either alone or along with infiltration of other adjacent structures. Even though trachea is infiltrated, adequate resection is the main modality of treatment in these patients. We retrospectively analysed carcinoma thyroid patients who were operated at our institute, between January 2011 and December 2018, and underwent thyroidectomy with tracheal or laryngeal resection. Seventeen...
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PARIS--(BUSINESS WIRE)--AIIMS (New Delhi, Inde) et Biolog-id ont terminé avec succès le protocole d'évaluation de la solution Biolog-id Transfusion®.
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NUOVA DELHI--(BUSINESS WIRE)--A conclusione della fase preliminare di una collaborazione avviata quasi 18 mesi fa, l'AIIMS (Nuova Delhi, India) e Biolog-id (Parigi, Francia) hanno completato con successo un protocollo di valutazione in più fasi della soluzione Transfusion® di Biolog-id. Lo studio è stato progettato per convalidare, nell'ambito di questo prestigioso istituto, la totale gestione e tracciabilità delle sacche di globuli rossi (RBC), dalla qualificazione alla trasfusione di sangue n
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