• Long-Term Recipient Health-Related Quality of Life and Donor-Recipient Relationship Following Sibling Pediatric Hematopoietic Stem Cell Transplantation.

  Related ArticlesLong-Term Recipient Health-Related Quality of Life and Donor-Recipient Relationship Following Sibling Pediatric Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2019 Oct 14;: Authors: Zając-Spychała O, Pieczonka A, Barańska M, Wachowiak J Abstract BACKGROUND: Despite the fact that the choice of donors and the number of sources of hematopoietic stem cells have inc

  Oncology

  Fri Oct 18, 2019 04:23
• CAR T-cell Therapy in Hematologic Malignancies: A Voyage in Progress.

  Related ArticlesCAR T-cell Therapy in Hematologic Malignancies: A Voyage in Progress. Clin Pharmacol Ther. 2019 Oct 17;: Authors: Holstein SA, Lunning MA Abstract The development of chimeric antigen receptor (CAR) T-cell therapy for select hematological malignancies represents one of the most remarkable therapeutic advances in the past decade. Currently, CD19-targeted CAR T-cell therapy is approved f

  Oncology

  Fri Oct 18, 2019 04:23
• Life experiences of adolescents with cancer in Turkey: a phenomenological study.

  Related ArticlesLife experiences of adolescents with cancer in Turkey: a phenomenological study. J Pak Med Assoc. 2019 Oct;69(10):1464-1469 Authors: Kostak MA, Semerci R, Eren T, Avci G, Savran F Abstract OBJECTIVE: To explore life experiences of adolescents after cancer diagnosis. METHODS: The phenomenological qualitative study was conducted at the paediatric oncology clinic of a university

  Oncology

  Fri Oct 18, 2019 04:23
• Pretreatment Vitamin D Deficiency Is Associated With Impaired Progression-Free and Overall Survival in Hodgkin Lymphoma.

  Related ArticlesPretreatment Vitamin D Deficiency Is Associated With Impaired Progression-Free and Overall Survival in Hodgkin Lymphoma. J Clin Oncol. 2019 Oct 17;:JCO1900985 Authors: Borchmann S, Cirillo M, Goergen H, Meder L, Sasse S, Kreissl S, Bröckelmann PJ, von Tresckow B, Fuchs M, Ullrich RT, Engert A Abstract PURPOSE: Vitamin D deficiency is described as a modifiable risk factor for the incid

  Oncology

  Fri Oct 18, 2019 04:23
• The safety of rolapitant for the treatment of nausea and vomiting associated with chemotherapy.

  Related ArticlesThe safety of rolapitant for the treatment of nausea and vomiting associated with chemotherapy. Expert Opin Drug Saf. 2019 Oct 17;: Authors: Navari RM Abstract Introduction: Chemotherapy-induced nausea and vomiting is a significant clinical issue that affects patients quality of life as well as treatment decisions. Significant improvements in the control of chemotherapy-induced nausea

  Oncology

  Fri Oct 18, 2019 04:23
• Whole-genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation.

  Related ArticlesWhole-genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation. J Pathol. 2019 Oct 17;: Authors: Paulsson JO, Backman S, Wang N, Stenman A, Crona J, Thutkawkorapin J, Ghaderi M, Tham E, Stålberg P, Zedenius J, Juhlin CC Abstract The genetics underlying thyroid cancer dedifferentiation is only partly understood and has not y

  Oncology

  Fri Oct 18, 2019 04:23
• First application of a high resolution silicon detector for proton beam Bragg peak detection in a 0.95 T magnetic field.

  Related ArticlesFirst application of a high resolution silicon detector for proton beam Bragg peak detection in a 0.95 T magnetic field. Med Phys. 2019 Oct 17;: Authors: Causer TJ, Schellhammer SM, Gantz S, Lühr A, Hoffmann AL, Metcalfe PE, Rosenfeld AB, Guatelli S, Petasecca M, Oborn BM Abstract PURPOSE: To report on experimental results of a high spatial resolution silicon based detector exposed to

  Oncology

  Fri Oct 18, 2019 04:23
• A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility.

  Related ArticlesA systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility. Asian J Androl. 2019 Oct 15;: Authors: Giudice FD, Busetto GM, De Berardinis E, Sperduti I, Ferro M, Maggi M, Gross MS, Sciarra A, Eisenberg ML Abstract Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with l

  Oncology

  Fri Oct 18, 2019 04:23
• Patient preferences for attributes of tyrosine kinase inhibitor treatments for EGFR mutation-positive non-small-cell lung cancer.

  Related ArticlesPatient preferences for attributes of tyrosine kinase inhibitor treatments for EGFR mutation-positive non-small-cell lung cancer. Future Oncol. 2019 Oct 17;: Authors: Bridges JF, la Cruz M, Pavilack M, Flood E, Janssen EM, Chehab N, Fernandes AW Abstract Aim: EGFR-tyrosine kinase inhibitors (TKIs) vary in efficacy, side effects (SEs) and dosing regimen. We explored EGFR-TKI treatment

  Oncology

  Fri Oct 18, 2019 04:23
• Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study.

  Related ArticlesPrecision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study. J Cancer Res Clin Oncol. 2019 Oct 16;: Authors: Guadagni S, Fiorentini G, De Simone M, Masedu F, Zoras O, Mackay AR, Sarti D, Papasotiriou I, Apostolou P, Catarci M, Clementi M, Ricevuto E, Bruera G Abstract BACKGROUND: Third line innovat

  Oncology

  Fri Oct 18, 2019 03:23
• Effectiveness of Gamma Knife Radiosurgery in the Treatment of Refractory Trigeminal Neuralgia: A Case Series.

  Related ArticlesEffectiveness of Gamma Knife Radiosurgery in the Treatment of Refractory Trigeminal Neuralgia: A Case Series. Oper Neurosurg (Hagerstown). 2019 Oct 17;: Authors: Tavakol S, Jackanich A, Strickland BA, Marietta M, Ravina K, Yu C, Chang EL, Giannotta S, Zada G Abstract BACKGROUND: Medical management is the first line of treatment for trigeminal neuralgia (TN). Patients with medically re

  Oncology

  Fri Oct 18, 2019 03:23
• Quality Assessment in Supportive Care in Head and Neck Cancer.

  Related ArticlesQuality Assessment in Supportive Care in Head and Neck Cancer. Front Oncol. 2019;9:926 Authors: Bonomo P, Paderno A, Mattavelli D, Zenda S, Cavalieri S, Bossi P Abstract Quality assessment is a key issue in every clinical intervention, to be periodically performed so to measure the adherence to standard and to possibly implement strategies to improve its performance. This topic is rar

  Oncology

  Fri Oct 18, 2019 03:23
• Statistical Analysis of Survival Models Using Feature Quantification on Prostate Cancer Histopathological Images.

  Related ArticlesStatistical Analysis of Survival Models Using Feature Quantification on Prostate Cancer Histopathological Images. J Pathol Inform. 2019;10:30 Authors: Ren J, Singer EA, Sadimin E, Foran DJ, Qi X Abstract Background: Grading of prostatic adenocarcinoma is based on the Gleason scoring system and the more recently established prognostic grade groups. Typically, prostate cancer grading is

  Oncology

  Fri Oct 18, 2019 03:23
• Biomarkers and Preclinical Models for Adult T-Cell Leukemia-Lymphoma Treatment.

  Related ArticlesBiomarkers and Preclinical Models for Adult T-Cell Leukemia-Lymphoma Treatment. Front Microbiol. 2019;10:2109 Authors: Ratner L Abstract Adult T-cell leukemia/lymphoma (ATL) is an aggressive lymphoproliferative malignancy with a very poor prognosis. Despite several recent advances, new therapeutic approaches are critical, and this will require successful preclinical studies, including

  Oncology

  Fri Oct 18, 2019 03:23
• Embracing the complexity: Older adults with cancer-related cognitive decline-A Young International Society of Geriatric Oncology Position Paper.

  Related ArticlesEmbracing the complexity: Older adults with cancer-related cognitive decline-A Young International Society of Geriatric Oncology Position Paper. J Geriatr Oncol. 2019 Oct 13;: Authors: Pergolotti M, Battisti NML, Padgett L, Sleight AG, Abdallah M, Newman R, Van Dyk K, Covington KR, Williams GR, van den Bos F, Pollock Y, Salerno EA, Magnuson A, Gattás-Vernaglia IF, Ahles TA Abstract Ca

  Oncology

  Fri Oct 18, 2019 03:23
• Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study.

  Related ArticlesUnderrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study. J Geriatr Oncol. 2019 Oct 13;: Authors: Tack L, Lefebvre T, Lycke M, Pottel L, Cool L, Ketelaars L, De Zutter J, Martens E, Pottel H, Stellamans K, Van Eygen K, Werbrouck P, Vergauwe P, Wildiers H, Schofield P, Boterberg T, Debruyne PR Abstract OBJECTIVE

  Oncology

  Fri Oct 18, 2019 03:23
• Elective nodal irradiation versus involved-field irradiation in patients with esophageal cancer receiving neoadjuvant chemoradiotherapy: a network meta-analysis.

  Related ArticlesElective nodal irradiation versus involved-field irradiation in patients with esophageal cancer receiving neoadjuvant chemoradiotherapy: a network meta-analysis. Radiat Oncol. 2019 Oct 16;14(1):176 Authors: Liu T, Ding S, Dang J, Wang H, Chen J, Li G Abstract BACKGROUND: To assess the comparative efficacy and safety of elective nodal irradiation (ENI) and involved-field irradiation (I

  Oncology

  Fri Oct 18, 2019 03:23
• Failure to Rescue as an Outcome Metric for Pediatric and Congenital Cardiac Catheterization Laboratory Programs: Analysis of Data From the IMPACT Registry.

  Related ArticlesFailure to Rescue as an Outcome Metric for Pediatric and Congenital Cardiac Catheterization Laboratory Programs: Analysis of Data From the IMPACT Registry. J Am Heart Assoc. 2019 Nov 05;8(21):e013151 Authors: O'Byrne ML, Kennedy KF, Jayaram N, Bergersen LJ, Gillespie MJ, Dori Y, Silber JH, Kawut SM, Rome JJ, Glatz AC Abstract Background Risk-adjusted adverse event (AE) rates have been

  Oncology

  Fri Oct 18, 2019 03:23
• Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting.

  Related ArticlesProceedings of the fourth international molecular pathological epidemiology (MPE) meeting. Cancer Causes Control. 2019 Aug;30(8):799-811 Authors: Campbell PT, Ambrosone CB, Nishihara R, Aerts HJWL, Bondy M, Chatterjee N, Garcia-Closas M, Giannakis M, Golden JA, Heng YJ, Kip NS, Koshiol J, Liu XS, Lopes-Ramos CM, Mucci LA, Nowak JA, Phipps AI, Quackenbush J, Schoen RE, Sholl LM, Tamimi RM, Wang M, Weije

  Oncology

  Fri Oct 18, 2019 03:23
• Eglerisine, a Novel Sesquiterpenoid Tropolone from Dulacia egleri with Antiproliferative Effect against an Acute Myeloid Leukemia Lineage.

  Related ArticlesEglerisine, a Novel Sesquiterpenoid Tropolone from Dulacia egleri with Antiproliferative Effect against an Acute Myeloid Leukemia Lineage. Planta Med. 2019 Oct 17;: Authors: R de Novais LM, Ferreira LF, de Sousa PT, Ribeiro TAN, Jacinto MJ, Dos Santos CHC, de Carvalho MG, Torquato HFV, Paredes-Gamero EJ, Silva VCP Abstract Chemical investigation of the stems of Dulacia egleri resulted

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 04:18
• Antitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells.

  Related ArticlesAntitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells. J Nat Prod. 2019 Oct 17;: Authors: Kim D, Wang CY, Hu R, Lee JY, Luu TT, Park HJ, Lee SK Abstract A flavonoid glycoside, quercitrin (1), and two phenylpropanoyl sucrose derivatives, vanicoside B (2) and lapathoside C (3), were isolated for the first time f

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 04:18
• G-quadruplex Binding Small Molecule Induces Synthetic Lethality in Breast Cancer Cells by Inhibiting c-MYC and BCL2 Expression.

  Related ArticlesG-quadruplex Binding Small Molecule Induces Synthetic Lethality in Breast Cancer Cells by Inhibiting c-MYC and BCL2 Expression. Chembiochem. 2019 Oct 17;: Authors: Paul R, Das T, Debnath M, Chauhan A, Dash J Abstract Herein, we describe a prolinamide derived peptidomimetic that preferentially binds to c-MYC and BCL2 G-quadruplexes present in the promoter regions of apoptosis related g

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 04:18
• Cytoplasmic retention and degradation of a mitotic inducer enable plant infection by a pathogenic fungus.

  Related ArticlesCytoplasmic retention and degradation of a mitotic inducer enable plant infection by a pathogenic fungus. Elife. 2019 Oct 17;8: Authors: Bardetti P, Castanheira SM, Valerius O, Braus GH, Pérez-Martín J Abstract In the fungus Ustilago maydis, sexual pheromones elicit mating resulting in an infective filament able to infect corn plants. Along this process a G2 cell cycle arrest is manda

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 04:18
• Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road.

  Related ArticlesCell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road. Bioessays. 2019 Oct 16;:e1900127 Authors: Liebl MC, Hofmann TG Abstract Mild and massive DNA damage are differentially integrated into the cellular signaling networks and, in consequence, provoke different cell fate decisions. After mild damage, the tumor suppressor p53 directs the cellular response

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• GEFT protein expression in digestive tract malignant tumors and its clinical significance. Related...

  GEFT protein expression in digestive tract malignant tumors and its clinical significance.Related ArticlesGEFT protein expression in digestive tract malignant tumors and its clinical significance. Oncol Lett. 2019 Nov;18(5):5577-5590 Authors: Wang Y, Zhang B, Gao G, Zhang Y, Xia Q Abstract Guanine nucleotide exchange factor T (GEFT), a member of the Rho guanine nucleotide exchange factor family, is expressed in a variety of tumors. In the present

  www Αλέξανδρος Γ. Σφακιανάκης

  Sun Oct 20, 2019 02:47
• AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.

  Related ArticlesAMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells. J Cell Physiol. 2019 Oct 16;: Authors: Wang F, Cao M, Fan M, Wu H, Huang W, Zhang Y, Hu Z, Jin X Abstract 10-hydroxycamptothecin (HCPT), a natural plant extract, exerts anticancer capacity. HCPT has been reported to induce apoptosis and autophagy in human ca

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma.

  Related ArticlesAnticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019;9:911 Authors: Huang YC, Lee PC, Wang JJ, Hsu YC Abstract The incidence and mortality of oral squamous cell carcinoma (OSCC) are high, and the number of oral cancers had risen in the world. However, chemotherapy drugs have numerous side effects. There is an urgent requirement to deve

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Neoantimycin F, a Streptomyces-Derived Natural Product Induces Mitochondria-Related Apoptotic Death in Human Non-Small Cell Lung Cancer Cells.

  Related ArticlesNeoantimycin F, a Streptomyces-Derived Natural Product Induces Mitochondria-Related Apoptotic Death in Human Non-Small Cell Lung Cancer Cells. Front Pharmacol. 2019;10:1042 Authors: Liu L, Zhu H, Wu W, Shen Y, Lin X, Wu Y, Liu L, Tang J, Zhou Y, Sun F, Lin HW Abstract Streptomyces-derived natural products have been become a major focus of anti-tumor drug discovery studies. Neoantimyci

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence.

  Related ArticlesPentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence. Sci Rep. 2019 Oct 16;9(1):14867 Authors: Lestari B, Nakamae I, Yoneda-Kato N, Morimoto T, Kanaya S, Yokoyama T, Shionyu M, Shirai T, Meiyanto E, Kato JY Abstract We previously showed that curcumin, a phytopolyphenol found in turmeric (

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells.

  Related ArticlesThe RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells. J Biol Chem. 2019 Oct 16;: Authors: Sherman EJ, Mitchell DC, Garner AL Abstract MicroRNAs (miRNAs or miRs) are small, noncoding RNAs that are implicated in the regulation of most biological processes. Global miRNA biogenesis is altered in many cancers, and RNA-binding proteins (RBP

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix.

  Related ArticlesJAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix. Arthritis Res Ther. 2019 Oct 16;21(1):213 Authors: Long J, Wang X, Du X, Pan H, Wang J, Li Z, Liu H, Li X, Zheng Z Abstract BACKGROUND: Intervertebral disc degeneration (IVDD)-related disorders are the major causes of low back pain. A previous study suggested th

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Tyrosine kinase inhibitors and immune checkpoint inhibitors-induced thyroid disorders.

  Related ArticlesTyrosine kinase inhibitors and immune checkpoint inhibitors-induced thyroid disorders. Crit Rev Oncol Hematol. 2019 Sep;141:23-35 Authors: Jannin A, Penel N, Ladsous M, Vantyghem MC, Do Cao C Abstract Recently, tyrosine kinase inhibitors (TKI) and immune checkpoint inhibitors (ICPIs) have emerged as new classes of anticancer therapies. Although generally considered less toxic than cyt

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Shikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways.

  Related ArticlesShikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):626-635 Authors: Liu Y, Kang X, Niu G, He S, Zhang T, Bai Y, Li Y, Hao H, Chen C, Shou Z, Li B Abstract Shikonin, a botanical drug extracted from Lithospermum erythrorhizon, exhibits anti-cancer effects in various

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia.

  Related ArticlesDiscovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia. J Med Chem. 2019 01 24;62(2):875-892 Authors: Liang X, Wang B, Chen C, Wang A, Hu C, Zou F, Yu K, Liu Q, Li F, Hu Z, Lu T, Wang J, Wang L, Weisberg EL, Li L, Xi

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity.

  Related ArticlesDiscovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity. J Med Chem. 2019 01 24;62(2):993-1013 Authors: Li W, Xu F, Shuai W, Sun H, Yao H, Ma C, Xu S, Yao H, Zhu Z, Yang DH, Chen ZS, Xu J Abstract A series of novel quinoline-chalcone derivatives were designed, synthesized, and evaluated for their antiproliferativ

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Synthesis and identification of 2,4-bisanilinopyrimidines bearing 2,2,6,6-tetramethylpiperidine-N-oxyl as potential Aurora A inhibitors.

  Related ArticlesSynthesis and identification of 2,4-bisanilinopyrimidines bearing 2,2,6,6-tetramethylpiperidine-N-oxyl as potential Aurora A inhibitors. Bioorg Med Chem. 2019 01 01;27(1):65-78 Authors: Sang CY, Qin WW, Zhang XJ, Xu Y, Ma YZ, Wang XR, Hui L, Chen SW Abstract The Aurora kinases are a family of serine/threonine kinases that interact with components of the mitotic apparatus and serve as

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion.

  Related ArticlesAbsence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion. Curr Biol. 2018 09 10;28(17):2837-2844.e3 Authors: Silva RD, Mirkovic M, Guilgur LG, Rathore OS, Martinho RG, Oliveira RA Abstract The fidelity of mitosis depends on cohesive forces that keep sister chromatids together. This is mediated by cohesin that embraces sister chromatid

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Loss of Kif18A Results in Spindle Assembly Checkpoint Activation at Microtubule-Attached Kinetochores.

  Related ArticlesLoss of Kif18A Results in Spindle Assembly Checkpoint Activation at Microtubule-Attached Kinetochores. Curr Biol. 2018 09 10;28(17):2685-2696.e4 Authors: Janssen LME, Averink TV, Blomen VA, Brummelkamp TR, Medema RH, Raaijmakers JA Abstract The spindle assembly checkpoint (SAC) halts anaphase progression until all kinetochores have obtained bipolar, stable attachments to the mitotic s

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Inhibition of WEE1 kinase and cell cycle checkpoint activation sensitizes head and neck cancers to natural killer cell therapies.

  Related ArticlesInhibition of WEE1 kinase and cell cycle checkpoint activation sensitizes head and neck cancers to natural killer cell therapies. J Immunother Cancer. 2018 06 21;6(1):59 Authors: Friedman J, Morisada M, Sun L, Moore EC, Padget M, Hodge JW, Schlom J, Gameiro SR, Allen CT Abstract BACKGROUND: Natural killer (NK) cells recognize and lyse target tumor cells in an MHC-unrestricted fashion

  pubmed: cell cycle arrest

  Fri Oct 18, 2019 03:17
• Early Red Flags Associated with Delayed Discharge in Patients Undergoing Gastrectomy: Analysis of Perioperative Variables and ERAS Protocol Items.

  Related ArticlesEarly Red Flags Associated with Delayed Discharge in Patients Undergoing Gastrectomy: Analysis of Perioperative Variables and ERAS Protocol Items. World J Surg. 2019 Oct 16;: Authors: Parise P, Cinelli L, Ferrari C, Cossu A, Puccetti F, Garutti L, Elmore U, Rosati R Abstract BACKGROUND: Enhanced Recovery After Surgery (ERAS) perioperative pathways are safe and effective for patients u

  pubmed: "world j surg"[jour]

  Fri Oct 18, 2019 03:17
• Repeat Hepatectomy for Early Recurrence of Colorectal Liver Metastases-Prognostic Impacts Assessed from the Recurrence Pattern.

  Related ArticlesRepeat Hepatectomy for Early Recurrence of Colorectal Liver Metastases-Prognostic Impacts Assessed from the Recurrence Pattern. World J Surg. 2019 Oct 16;: Authors: Watanabe G, Mise Y, Ito H, Inoue Y, Ishizawa T, Takahashi Y, Saiura A Abstract BACKGROUND: It is unclear how early liver recurrence negatively affects survival in patients undergoing surgery for colorectal liver metastases

  pubmed: "world j surg"[jour]

  Fri Oct 18, 2019 03:17
• Future Oncology; +27 new citations

  27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/10/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

  pubmed: future oncology

  Fri Oct 18, 2019 03:11
• The Middle/Later Stone Age transition and cultural dynamics of late Pleistocene East Africa.

  Related ArticlesThe Middle/Later Stone Age transition and cultural dynamics of late Pleistocene East Africa. Evol Anthropol. 2019 Sep;28(5):267-282 Authors: Tryon CA Abstract The Middle to Later Stone Age (MSA/LSA) transition is a prominent feature of the African archeological record that began in some places ~30,000-60,000 years ago, historically associated with the origin and/or dispersal of "moder

  pubmed: "evol anthropol"[jou...

  Fri Oct 18, 2019 04:38
• Unilateral segmental agenesis of the vertebral artery at the C2 level.

  Related ArticlesUnilateral segmental agenesis of the vertebral artery at the C2 level. Surg Radiol Anat. 2019 Oct 16;: Authors: Gailloud P, Gautam A, Caplan J Abstract PURPOSE: To report a case of unilateral segmental agenesis of the vertebral artery (VA). METHODS: We describe the angiographic and MRI features of a segmental VA agenesis (C2 segment). RESULTS: VA agenesis is caused b

  radiol anat

  Fri Oct 18, 2019 03:08
• The infectious thyroid nodule: a case report of mucormycosis associated with ibrutinib therapy.

  Related ArticlesThe infectious thyroid nodule: a case report of mucormycosis associated with ibrutinib therapy. J Otolaryngol Head Neck Surg. 2019 Oct 16;48(1):49 Authors: Mascarella MA, Schweitzer L, Alreefi M, Silver J, Caglar D, Loo VG, Richardson K, Dufresne P, Lee TC, Sadeghi N Abstract BACKGROUND: Acute invasive fungal infections of the head and neck secondary to tyrosine kinase inhibitors are

  Dysphonia

  Fri Oct 18, 2019 03:06
• Efficacy of Conversation Training Therapy for Patients With Benign Vocal Fold Lesions and Muscle Tension Dysphonia Compared to Historical Matched Control Patients.

  Related ArticlesEfficacy of Conversation Training Therapy for Patients With Benign Vocal Fold Lesions and Muscle Tension Dysphonia Compared to Historical Matched Control Patients. J Speech Lang Hear Res. 2019 Oct 17;:1-18 Authors: Gillespie AI, Yabes J, Rosen CA, Gartner-Schmidt JL Abstract Purpose Conversation training therapy (CTT) is the 1st voice therapy approach to eliminate the traditional ther

  Dysphonia

  Fri Oct 18, 2019 03:06
• [Thyroid tumors in the adult revealed by unilateral laryngeal paralysis].

  Related Articles[Thyroid tumors in the adult revealed by unilateral laryngeal paralysis]. Presse Med. 2019 Sep;48(9):e267-e271 Authors: Alciato L, Rubin F, Villeneuve A, La Croix C, Bonfils P, Laccourreye O Abstract GOAL: To analyze the characteristic of thyroid tumor associated with ipsilateral unilateral laryngeal paralysis (ULP) in the adult patient. MATERIALS AND METHODS: Retrospective a

  Dysphonia

  Fri Oct 18, 2019 03:06
• Accuracy of global and/or regional anthropometric measurements of adiposity in screening sleep apnea: the ELSA-Brasil cohort.

  Related ArticlesAccuracy of global and/or regional anthropometric measurements of adiposity in screening sleep apnea: the ELSA-Brasil cohort. Sleep Med. 2019 Jun 14;63:115-121 Authors: Santos RB, Silva WA, Parise BK, Giatti S, Aielo AN, Souza SP, Santos IS, Lotufo PA, Bensenor IM, Drager LF Abstract OBJECTIVE: Adiposity is a well-established risk factor for obstructive sleep apnea (OSA) but the exist

  pubmed: sleep apnea

  Fri Oct 18, 2019 04:28
• The wrist is not the brain: Estimation of sleep by clinical and consumer wearable actigraphy devices is impacted by multiple patient- and device-specific factors.

  Related ArticlesThe wrist is not the brain: Estimation of sleep by clinical and consumer wearable actigraphy devices is impacted by multiple patient- and device-specific factors. J Sleep Res. 2019 Oct 17;:e12926 Authors: Danzig R, Wang M, Shah A, Trotti LM Abstract Clinical actigraphy devices provide adequate estimates of some sleep measures across large groups. In practice, providers are asked to ap

  pubmed: sleep apnea

  Fri Oct 18, 2019 03:05
• Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations.

  Related ArticlesNonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations. Transl Gastroenterol Hepatol. 2019;4:65 Authors: Kovalic AJ, Cholankeril G, Satapathy SK Abstract The progression of liver disease is portrayed by several common, overarching signs and symptoms. Classically, these include findings such as spider angiomata, jaundice, palmar er

  pubmed: sleep apnea

  Fri Oct 18, 2019 03:05
• Very low frequency component of heart rate variability as a marker for therapeutic efficacy in patients with obstructive sleep apnea: Preliminary study.

  Related ArticlesVery low frequency component of heart rate variability as a marker for therapeutic efficacy in patients with obstructive sleep apnea: Preliminary study. J Res Med Sci. 2019;24:84 Authors: Noda A, Hayano J, Ito N, Miyata S, Yasuma F, Yasuda Y Abstract Background: Although positive airway pressure (PAP) therapy is effective for treating obstructive sleep apnea (OSA), some patients with

  pubmed: sleep apnea

  Fri Oct 18, 2019 03:05
• Occlusion: Time to debate malocclusion.

  Related ArticlesOcclusion: Time to debate malocclusion. Br Dent J. 2018 09 14;225(5):376-377 Authors: Mew M PMID: 30215389 [PubMed - indexed for MEDLINE]

  pubmed: sleep apnea

  Fri Oct 18, 2019 03:05
• Rhythmic calcium transients in smooth muscle cells of the mouse internal anal sphincter

  The SW and CT frequency is greatest at the distal IAS where basal Ca2+ is most elevated. We propose that ICC‐IM generate SWs that give rise to CTs and that basal Ca2+ is elevated because of the inability to reduce [Ca2+]i between high frequency SWs; this contributes to IAS tone.. Abstract Background The internal anal sphincter (IAS) exhibits slow waves (SWs) and tone that are dependent upon L‐type Ca2+ channels (CavL) suggesting that phasic

  The European Gastrointestinal Motility Society

  Fri Oct 18, 2019 01:36
• A very timely meta-analysis on Omalizumab in chronic spontaneous urticaria

  Publication date: November–December 2019Source: Allergologia et Immunopathologia, Volume 47, Issue 6Author(s): Luis Garcia-Marcos

  Allergologia et Immunopathologia

  Fri Oct 18, 2019 02:49
• Occult Spontaneous Ocular Perforation Presenting as Conjunctival Chemosis in a Patient with Marfan’s Syndrome

  We report a case of occult spontaneous ocular perforation presenting as conjunctival chemosis in a patient with Marfan’s syndrome (MFS). A 38-year-old female with MFS presented with bilateral conjunctival chemosis since 6 months. Best-corrected visual acuity was 20/20 in both eyes. On slit-lamp examination, a diffuse conjunctival chemosis was observed in both eyes without any signs of ocular hypotony (decreased visual acuity, low intraocular pres

  Case Reports in Ophthalmology

  Fri Oct 18, 2019 00:33
• The walnut genetic resources of INRA: chronological phenotypic data and ontology

  Persian walnut (Juglans regia L.), the walnut species cultivated for nut production, is grown worldwide in temperate areas. In this work, chronological phenotypic data have been collected regarding a part of the ...

  BMC Research Notes

  Wed Oct 16, 2019 17:00
• Development of an administrative definition for celiac disease

  The investigation and management of celiac disease places a high burden on the health care system. Accurate methods to ascertain cases of celiac disease (CD) in population-based administrative data can facilit...

  BMC Research Notes

  Wed Oct 16, 2019 17:00
• Status of perceived social support and its associated factors among inmate prisoners in Northwest Amhara, Ethiopia

  The objective of this study was to determine the level of social support and associated factors in selected prison institutions in Amhara region, Ethiopia.

  BMC Research Notes

  Wed Oct 16, 2019 17:00
• Effects of the monoamine stabilizer (-)OSU6162 on cognitive function in alcohol dependence

  Abstract Introduction Alcohol dependence (AD) is associated with a dysregulated mesolimbocortical dopamine system—a pathway which is also implicated in both reward and cognition. The monoamine stabilizer (-)-OSU6162 (OSU) is a novel pharmacological compound with the ability to reduce ethanol intake and ethanol seeking in long-term drinking rats as well as reducing alcohol craving in AD

  Latest Results for Psychopharmacology

  Thu Oct 17, 2019 17:00
• nkx3.2 mutant zebrafish accommodate jaw joint loss through a phenocopy of the head shapes of Paleozoic jawless fish [NEW RESULTS]

  The vertebrate jaw is a versatile feeding apparatus that facilitated explosive diversification. To function, it requires a joint between the upper and lower jaws, so jaw joint defects - such as osteoarthritis or even ankylosis - are often highly disruptive and difficult to study. To describe consequences of jaw-joint dysfunction, we engineered two independent null alleles of a single jaw-joint marker gene, nkx3.2, in zebrafish. These mutations ca

  bioRxiv Subject Collection: Evolutionary Biology

  Thu Oct 17, 2019 17:00
• Acute Effects of Foam Rolling on Range of Motion in Healthy Adults: A Systematic Review with Multilevel Meta-analysis

  Abstract Background Foam rolling (FR) has been demonstrated to acutely enhance joint range of motion (ROM). However, data syntheses pooling the effect sizes across studies are scarce. It is, furthermore, unknown which moderators affect the treatment outcome. Objective To quantify the immediate effects of

  Latest Results for Sports Medicine

  Thu Oct 17, 2019 17:00
• More about Factor H Autoantibodies in Membranous Nephropathy

  To the Editor: Primary membranous nephropathy, one of the most common causes of nephrotic syndrome in adults, results from the deposition of IgG and complement components in the subepithelial layer of the glomerular basement membrane. In 70 to 80% of patients with this condition, antibodies that…

  The New England Journal of Medicine: Search Results in Allergy\Immunology

  Wed Oct 16, 2019 17:00