Condition: Breast Cancer Intervention: Drug: Onapristone Sponsor: SOLTI Breast Cancer Research Group Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: HIV Infection; Human Papillomavirus Infection; Human Papillomavirus-Related Carcinoma Interventions: Other: Cytology Specimen Collection Procedure; Procedure: High Resolution Anoscopy with Biopsy; Other: Laboratory Biomarker Analysis; Procedure: Medical Examination; Procedure: Physical Examination; Other: Questionnaire Administration Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message:...
Condition: Hepatocellular Carcinoma Interventions: Drug: Sorafenib; Procedure: Transarterial chemoembolization Sponsor: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Condition: Breast Cancer Intervention: Drug: Enzalutamide Sponsor: SOLTI Breast Cancer Research Group Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Colorectal Cancer Liver Metastases Interventions: Diagnostic Test: [18-F]- FDG - PET; Procedure: Thermal ablation (TA); Diagnostic Test: PET/CT Scan Sponsor: Memorial Sloan Kettering Cancer Center Recruiting (Source: ClinicalTrials.gov)
Condition: Breast Cancer Intervention: Other: interview Sponsor: Centre Georges Francois Leclerc Recruiting (Source: ClinicalTrials.gov)
Condition: HIV Infection Interventions: Other: Cytology Specimen Collection Procedure; Other: Laboratory Biomarker Analysis; Procedure: Medical Examination; Procedure: Physical Examination; Procedure: Proctoscopy with Biopsy; Other: Questionnaire Administration Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI); Tata Memorial Hospital; Udaan Trust; University of Arkansas Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Squamous Cell Carcinomas Intervention: Other: solar irradiation and biopsies Sponsor: Centre Hospitalier Universitaire de Nice Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Hematological Malignancies Intervention: Sponsors: Tampere University Hospital; Tampere University; University of Eastern Finland Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion Intervention: Drug: larotrectinib(Vitrakvi, BAY2757556) Sponsor: Bayer Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Oncologic Disorders Intervention: Other: Care pathway Sponsors: Ilyse Kenis; Kom Op Tegen Kanker; KU Leuven; University Ghent Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Chronic Disease; Diabetes; Vascular Diseases; Chronic Lung Disease; Cancer; Psychiatric Disorder Intervention: Device: Telemedicine: tablet and possibly tools to perform measurements Sponsors: University of Oslo; Oslo Economics; Norwegian Centre for Rural Medicine; Norsk Gallup Institutt AS Recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Conditions: Stage IV Non-small Cell Lung Cancer; Stage IV Melanoma; Triple Negative Breast Cancer; Renal Cell Carcinoma Stage IV Intervention: Combination Product: ImmunicomAIAC Sponsor: Prof. Gal Markel Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Locally Advanced Cancer; Metastatic Cancer; Chronic Respiratory Failure; Chronic Heart Failure; Chronic Liver Failure; Chronic Renal Failure Intervention: Other: Screening for PC by means of two different screening tools Sponsor: Azienda Ospedaliera Città della Salute e della Scienza di Torino Completed (Source: ClinicalTrials.gov)
Condition: Metastatic Breast Cancer Intervention: Drug: Metformin Sponsor: Hager salah el din Recruiting (Source: ClinicalTrials.gov)
Condition: Musculoskeletal Malignancy Interventions: Behavioral: Personalized acceptance-based mindfulness exercise; Behavioral: Brief educational pamphlet Sponsor: Massachusetts General Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Gastrointestinal Stromal Tumor Interventions: Other: DNA extraction of tumer tissue samples and high-throughput sequencing of small panels; Other: DNA extraction of tumer tissue samples and blood sample and high-throughput sequencing of small panels Sponsors: The First Affiliated Hospital with Nanjing Medical University; Fudan University Recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with...
Condition: Pancreatic Adenocarcinoma Intervention: Sponsors: Van Andel Research Institute; Spectrum Health Hospitals; Mercy Health Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Metastatic Cancer; Advanced Cancer; Cancers That Cannot be Treated With Curative Intent Interventions: Genetic: Initiation of POG-related WGTA; Genetic: Usual care Sponsors: British Columbia Cancer Agency; BC Cancer Foundation; Genome British Columbia Active, not recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Condition: Gallbladder Neoplasms Intervention: Sponsors: Shanghai Jiao Tong University School of Medicine; The First Affiliated Hospital of Anhui Medical University; Anhui Provincial Hospital; First Affiliated Hospital Bengbu Medical College; LanZhou University; Henan Cancer Hospital; The First Affiliated Hospital of Zhengzhou University; The Second Affiliated Hospital of Harbin Medical University; First Affiliated Hospital of Harbin Medical University; Harbin Medical University;...
Conditions: Oligometastasis; Prostate Cancer Intervention: Radiation: local ablative radiotherapy Sponsor: Technische Universität Dresden Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Non Small Cell Lung Cancer; Advanced Solid Tumor; Metastatic Melanoma; Metastatic Head and Neck Carcinoma; Metastatic Renal Cell Carcinoma; Metastatic Colorectal Cancer; Sarcomas; Metastatic Prostate Cancer Interventions: Drug: ONC-392; Drug: Pembrolizumab Sponsor: OncoImmune, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Condition: Passive Exposure to Electronic Cigarette Aerosols Intervention: Other: No intervention Sponsors: Institut Català d'Oncologia; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; University of Stirling; Hellenic Cancer Society; Mario Negri Institute for Pharmacological Research Recruiting (Source: ClinicalTrials.gov)
Conditions: Neoplasms; Hiv; Cervical Cancer; Breast Cancer; HNSCC; Vulvar Cancer; Anal Cancer; Cancer Suspect Interventions: Other: Potlako intervention; Other: Enhanced care Sponsors: Brigham and Women's Hospital; Botswana Harvard Aids Institute; Dana-Farber Cancer Institute; National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey; University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Pancreas Cancer; Adenocarcinoma of the Pancreas Interventions: Drug: Digoxin; Drug: 5Fluorouracil; Drug: Calcium Leucovorin; Drug: Irinotecan; Drug: Oxaliplatin Sponsors: Jean Grem, MD; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Bronchoscopy; Lung Cancer; Solitary Pulmonary Nodule Intervention: Device: Archimedes procedure Sponsor: University Hospital, Limoges Not yet recruiting (Source: ClinicalTrials.gov)
Conditions: Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Locally Advanced Oropharyngeal Squamous Cell Carcinoma; Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVA Oropharyngeal (p16-Negative)...
Condition: Secondhand Exposure to Electronic Cigarette Intervention: Behavioral: Exposure to aerosol of electronic cigarette Sponsor: Institut Català d'Oncologia Completed (Source: ClinicalTrials.gov)
Conditions: Bone Metastases; Thyroid Cancer Interventions: Other: Administrative data; Other: Clinical data; Other: Histological data; Other: Imaging data; Other: Biological data; Other: Further treatment Sponsor: Hospices Civils de Lyon Not yet recruiting (Source: ClinicalTrials.gov)
"I wish I had known sooner that the persistent stomach pain I experienced prior to my diagnosis was a symptom of pancreatic cancer," the "Jeopardy!" host said (Source: Health News: CBSNews.com)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Jeopardy! host Alex Trebek, 79, appeared in a PSA on YouTube to raise awareness about the signs and symptoms of pancreatic cancer and asked viewer to 'join me in this fight'. (Source: the Mail online | Health)
Bariatric surgery and the weight loss that follows it lead to a markedly reduced incidence of skin cancer, including melanoma, concludes a new study.Medscape Medical News (Source: Medscape Medical News Headlines)
The Texas Biomedical Research Institute, Southwest Research Institute and UT Health San Antonio are teaming on a nonsurgical treatment for bladder cancer. Texas Biomed professor Jordi Torrelles and UT Health San Antonio’s Dr. Robert Svatek will be principle investigators on the new project. They will study the use of a modified Mycobacterium bovis Bacillus Calmette et Guérin, or BCG, vaccine as a treatment for a type of cancer that is expected t o affect more than 2% of the world’s population…...
Growth in Japan and Latin America helped power GE Healthcare to higher revenues...Read more on AuntMinnie.comRelated Reading: GE, Premier partner on one-stop breast cancer center GE lands 10-year deal with NYC Health + Hospitals GE, Theragnostics partner on PSMA agent GE, partners to develop PET tracers GE inks deal for imaging antibodies (Source: AuntMinnie.com Headlines)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory...
This injection would make colorectal cancer cells glow, therefore easier to find and surgically remove. (Source: Forbes.com Healthcare News)
Researchers at the University of Pennsylvania found that glioblastoma patients with higher levels of a biomarker in their blood lived on average half as long after diagnosis and discovered new mutations. (Source: the Mail online | Health)
In 2017, the FDA warned health care providers and thermography device makers not to mislead people into believing thermal imaging could take the place of a mammogram.WebMD Health News (Source: Medscape Medical News Headlines)
25-year-old Jenna Schardt underwent brain surgery — while awake — in Texas on Tuesday, and the procedure was livestreamed on Facebook. Doctors with the Methodist Dallas Medical Center performed the surgery to remove a mass of tangled blood vessels in Schardt’s brain that had impaired her speech and caused seizures. At the beginning of the operation, Schardt was put under anesthesia so doctors could cut into her skull. Once they reached her brain, Schardt was woken up so she could speak and answer...
Heart disease, not a recurrence of cancer, is the No. 1 cause of death for breast cancer survivors and women overall (Source: Health News: CBSNews.com)
There may be unintended consequences of breast cancer treatment. More than 3.8 million breast cancer survivors live in the U.S. Recent advancements in early detection and treatment have saved many lives, but those treatments may also increase a woman ’s risk of cardiovascular disease. Cardiologist Dr. Tara Narula reports. (Source: Health News: CBSNews.com)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales...
SAN DIEGO, Oct. 30, 2019 -- (Healthcare Sales & Marketing Network) -- Invivoscribe, Inc. announced today that the European Commission (EC) has approved the Astellas drug XOSPATA (gilteritinib) as a monotherapy for the treatment of adult patients with rel... Diagnostics, Oncology, Regulatory Invivoscribe, Astellas, XOSPATA, gilteritinib, LeukoStrat CDx FLT3 (Source: HSMN NewsFeed)
Beatriz Farmer-Maia became noticeably more affectionate in July 2018. Her father, Tiago Maia, originally from Portugal, refused to leave hospital when he searched her symptoms online. (Source: the Mail online | Health)
WEDNESDAY, Oct. 30, 2019 -- Dietary fiber and yogurt consumption are associated with a reduced risk for lung cancer, according to a pooled analysis published online Oct. 24 in JAMA Oncology. Jae Jeong Yang, Ph.D., from the Vanderbilt University... (Source: Drugs.com - Pharma News)
BILL TURNBULL has provided an intimate window into his journey with prostate cancer, providing the public with an insight into his treatment process. Speaking on ITV ’s This Morning today, the former BBC presenter revealed taking CBD oil is one aspect of his disease management. (Source: Daily Express - Health)
Bayer , the world's largest maker of seeds and pesticides, said U.S. farmers were unperturbed by lawsuits seeking damages from Bayer for an alleged cancer-causing effect of glyphosate-based herbicides. (Source: Reuters: Health)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
(Natural News) A shocking new gene sequencing investigation has found that MMR vaccines are deliberately engineered to cause cancer as a repeat business model for Big Pharma, which manufactures vaccines and cancer treatment drugs for profit. MMR vaccines were found to contain the complete gene sequence of a specific human (aborted) baby whose genes were... (Source: NaturalNews.com)
Drugs can be safely delivered to cancerous lymph nodes via the lymphatic system and then released inside the nodes using sound waves. Tohoku University researchers tested the treatment on mice with metastatic breast cancer and published their findings in the journal Scientific Reports. (Source: World Pharma News)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate...
German chemicals group faces surge in plaintiffs alleging cancer link to Roundup (Source: FT.com - Drugs and Healthcare)
(Natural News) Each year, a million people are diagnosed with colon cancer globally and half a million die from it. It’s a startling statistic, but there is a silver lining here: It also happens to be one type of cancer where diet can play a huge role in both prevention and treatment. While diet can... (Source: NaturalNews.com)
British-Pakistani Saj Dar was given a disposable plate by her family, who feared she was infectious. (Source: BBC News | Health | UK Edition)
As oncology trials become more complex, scientists are finding that the oncogenic drivers of disease are crafting more discrete patient populations and are therefore turning what was once a very...(PRWeb October 30, 2019)Read the full story at https://www.prweb.com/releases/the_ever_increasing_impact_of_gene_therapy_in_rare_oncology_trials_upcoming_webinar_hosted_by_xtalks/prweb16686076.htm (Source: PRWeb: Medical Pharmaceuticals)
Funding Opportunity RFA-CA-20-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is associated with the Beau Biden Cancer MoonshotSM Initiative (https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative) that is intended to accelerate cancer research. The purpose of this FOA is to develop, test, and evaluate interventions and implementation approaches, or adapt existing approaches, to improve patient/provider/family risk communication and...
Conditions: Allergic Rhinitis Due to Dermatophagoides Farinae; Allergic Rhinitis Due to Dermatophagoides Pteronyssinus; Allergic Rhinitis Due to House Dust Mite Interventions: Biological: Sublingual allergy immunotherapy tablet; Other: Placebo Sponsor: ALK-Abelló A/S Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
The anterior alveolar ridge of the maxilla is a frequent site for pathology, most of it involving underlying bone and readily observable radiologically. Although much of this disease presents as well-defined unilocular radiolucencies arising adjacent to the apices of non-vital anterior teeth, thus being periapical radiolucencies of inflammatory origin (PRIO), a minority reflects more serious disease such as neoplasia. The most serious of the latter are malignancies, most frequently squamous cell...
To evaluate retrospectively the diagnostic usefulness of transrectal ultrasound (TRUS)-guided targeted biopsy (TB) for transition zone (TZ) prostate cancer (PCa) in patients with prebiopsy magnetic resonance imaging (MRI). (Source: Clinical Radiology)
No abstract available (Source: Journal of the American Academy of Physician Assistants)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
This article discusses appropriate methods of contraception for these patients. (Source: Journal of the American Academy of Physician Assistants)
This article reviews the three most common causes of viral hepatitis, screening guidelines, clinical features, medical management, approaches for primary prevention, and the natural history of untreated disease. (Source: Journal of the American Academy of Physician Assistants)
A drug that targets cancers with a mutated KRAS gene removed tumours in 8 out of 10 mice and shrunk tumours in 2 out of 4 people (Source: New Scientist - Health)
Nature, Published online: 30 October 2019; doi:10.1038/d41586-019-03275-zBrachytherapy is an established treatment for prostate cancer with much to recommend it, but its use is declining as clinicians opt for flashier therapies. (Source: Nature AOP)
We humans exhibit a peak cancer incidence in old age, around the early 80s, after which cancer rates decline from that peak. If aging is the continual accumulation of damage, then why do we observe this pattern of cancer incidence with age rather than a continual increase over time? It does not occur in mice, after all. Researchers here provide evidence for the explanation to involve reduced rates of cell division in later life, which may be one of many evolutionary adaptations connected to the unusual...
WEDNESDAY, Oct. 30, 2019 -- Patients aged 85 and older who have colon cancer surgery have high survival rates, a new study finds. People are living longer, so more seniors are being diagnosed with colon cancer, according to the authors of a study... (Source: Drugs.com - Daily MedNews)
CONCLUSION: This study reveals that patients' global satisfaction after hypnosis is high. This is significantly related to the quality of preoperative information and to the experience of the surgical team. It also suggests that patients are more likely to benefit from hypnosis if the surgery is longer. PMID: 31658815 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Risk of Mortality between Untreated and Treated Papillary Thyroid Cancer: A Matched Cohort Analysis.
CONCLUSIONS: Compared to treated patients, untreated PTC patients were at higher risk of death while low-risk untreated PTC patients had comparable rate of metastasis and no increased risk of all-cause mortality. Level of evidence: 3. PMID: 31658833 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
. (Source: International Journal of Audiology)
. (Source: International Journal of Audiology)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
. (Source: International Journal of Audiology)
This article reviews the evolving indications for cochlear implant, patient assessment, surgical approach, and outcomes for pediatric and adult cochlear implant that demonstrate its impact. Future concepts in cochlear implant are introduced briefly. This article covers a breadth of information; however, it is not intended be entirely comprehensive. Rather, it should serve as a foundation for understanding cochlear implant. (Source: Otolaryngologic clinics of North America)
One care team has launched Good Grief Rounds, using storytelling to debrief emotionally difficult cases, and others are using literature to foster empathy and engagement in the practice of medicine.Medscape Medical News (Source: Medscape Critical Care Headlines)
CONCLUSION: For patients with advanced malignant tumours with failure of standard therapy, administration of apatinib can still result in good efficacy. The efficacy of apatinib is better in patients with a higher performance status and lower degree of tumour progression. PMID: 31661009 [PubMed - in process] (Source: BMC Pharmacology and Toxicology)
ConclusionIn cases of malignancy and advanced age, NRI is a better predictor of immediate postoperative outcome than BMI. (Source: Annals of Medicine and Surgery)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Conclusions: Patients with acute HCV and thalassemia have low rates of spontaneous resolution of HCV infection and the majority develop chronic HCV. Direct acting antiviral combinations are associated with high SVR rates and low adverse event in treatment na ïve and experienced patients with chronic HCV and thalassemia. Liver fibrosis is accelerated in thalassemia patients with chronic HCV, therefore, early diagnosis, treatment with DAAs, adequate iron chelation and non-invasive monitoring liver...
Conclusions: BAL was a safe procedure also in thrombocytopenic patients, permitting an IPA diagnosis not otherwise identifiable using EORTC/MSG criteria. Our data suggest that a BAL GM value of>0.8 represents the most useful cut-off in terms of sensibility and specificity. Further prospective studies on a larger number of patients are needed to confirm these results. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Authors: Ernst A PMID: 31659378 [PubMed - as supplied by publisher] (Source: HNO)
CONCLUSION: The data presented show promising approaches for the further development of radiotherapy, particularly in terms of combined RCT as well as the optimal sequencing and dosing of systemic therapies. PMID: 31659379 [PubMed - as supplied by publisher] (Source: HNO)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Recent research has shown promising results for the development of a clinically feasible vestibular implant in the near future. However, correct electrode placement remains a challenge. It was shown that fluoroscopy was able to visualize the semicircular canal ampullae and electrodes, and guide electrode insertion in real time. Ninety-four percent of the 18 electrodes were implanted correctly ( (Source: Otolaryngologic clinics of North America)
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