• Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress.

  Related ArticlesCorrection: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress. Oncotarget. 2019 Oct 01;10(55):5724-5725 Authors: Lin YC, Wu MH, Wei TT, Lin YC, Huang WC, Huang LY, Lin YT, Chen CC Abstract [This corrects the article DOI: 10.18632/oncotarget.1628.].PMID: 31620247 [PubMed - in process]

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling.

  Related ArticlesGSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling. Oncotarget. 2019 Oct 01;10(55):5713-5723 Authors: Uemura T, Tsaprailis G, Gerner EW Abstract Polyamines spermidine and spermine, and their diamine precursor putrescine, are essential for normal cellular functions in both pro- and eukaryotes. Cellular polyamine levels are regulated by biosynthesis, degradation

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• Upregulation of C1-inhibitor in pancreatic cancer.

  Related ArticlesUpregulation of C1-inhibitor in pancreatic cancer. Oncotarget. 2019 Oct 01;10(55):5703-5712 Authors: Osther K, Förnvik K, Liljedahl E, Salford LG, Redebrandt HN Abstract Purpose: The complement system has recently sparked more interest in cancer research. The classical pathway is initiated by activation of the C1 complex, which irreversibly can be bound to and inhibited by C1-INH. We

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing.

  Related ArticlesComparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing. Oncotarget. 2019 Oct 01;10(55):5690-5702 Authors: Streubel A, Stenzinger A, Stephan-Falkenau S, Kollmeier J, Misch D, Blum TG, Bauer T, Landt O, Am Ende A, Schirmacher P, Mairinger T, Endris V Abstract The analysis of circulating cell-free DNA (cfDNA) extracted from perip

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• Clinical significance of evaluating hormone receptor and HER2 protein using cell block against metastatic breast cancer: a multi-institutional study.

  Related ArticlesClinical significance of evaluating hormone receptor and HER2 protein using cell block against metastatic breast cancer: a multi-institutional study. Oncotarget. 2019 Oct 01;10(55):5680-5689 Authors: Matsui A, Murata Y, Masuda N, Mori K, Takahashi M, Yamashiro K, Aogi K, Maeda S, Itou M, Ozaki S, Kuraoka K, Satou Y, Ichihara S, Tokunaga E, Taguchi K, Watanabe T, Suzuki H, Nagayama A, Nishimura R

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma.

  Related ArticlesInhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma. Oncotarget. 2019 Oct 01;10(55):5671-5679 Authors: Seligson ND, Stets CW, Demoret BW, Awasthi A, Grosenbacher N, Shakya R, Hays JL, Chen JL Abstract Dedifferentiated liposarcoma (DDLPS) is a highly morbid mesenchymal tumor characterized and driven by genomic amplificati

  Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/

  Fri Oct 18, 2019 04:54
• Incidence of Late Relapses in Patients With HER2-Positive Breast Cancer Receiving Adjuvant Trastuzumab: Combined Analysis of NCCTG N9831 (Alliance) and NRG Oncology/NSABP B-31.

  Related ArticlesIncidence of Late Relapses in Patients With HER2-Positive Breast Cancer Receiving Adjuvant Trastuzumab: Combined Analysis of NCCTG N9831 (Alliance) and NRG Oncology/NSABP B-31. J Clin Oncol. 2019 Oct 17;:JCO1900443 Authors: Chumsri S, Li Z, Serie DJ, Mashadi-Hossein A, Colon-Otero G, Song N, Pogue-Geile KL, Gavin PG, Paik S, Moreno-Aspitia A, Perez EA, Thompson EA Abstract PURPOSE: Re

  pubmed: her2-positive breast...

  Fri Oct 18, 2019 04:51
• Totality of Scientific Evidence in the Development of ABP 980, a Biosimilar to Trastuzumab.

  Related ArticlesTotality of Scientific Evidence in the Development of ABP 980, a Biosimilar to Trastuzumab. Target Oncol. 2019 Oct 16;: Authors: Kolberg HC, Colleoni M, Santi P, Demetriou GS, Segui-Palmer MA, Fujiwara Y, Hurvitz SA, Hanes V Abstract ABP 980 was developed as a biosimilar to trastuzumab, a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2), that is indicated

  pubmed: her2-positive breast...

  Fri Oct 18, 2019 04:51
• Risk Factors Associated with Trastuzumab-induced Cardiotoxicity in Patients with Human Epidermal Growth Factor Receptor 2-positive Breast Cancer.

  Related ArticlesRisk Factors Associated with Trastuzumab-induced Cardiotoxicity in Patients with Human Epidermal Growth Factor Receptor 2-positive Breast Cancer. J Pharm Bioallied Sci. 2019 Oct-Dec;11(4):348-354 Authors: Abdel-Razaq W, Alzahrani M, Al Yami M, Almugibl F, Almotham M, Alregaibah R Abstract Context: Although trastuzumab is a highly effective and selective targeted therapy for human epid

  pubmed: her2-positive breast...

  Fri Oct 18, 2019 04:51
• A TFAP2C Gene Signature is Predictive of Outcome in HER2-positive Breast Cancer.

  Related ArticlesA TFAP2C Gene Signature is Predictive of Outcome in HER2-positive Breast Cancer. Mol Cancer Res. 2019 Oct 16;: Authors: Wu VT, Kiriazov B, Koch KE, Gu VW, Beck AC, Borcherding N, Li T, Addo P, Wehrspan ZJ, Zhang W, Braun TA, Brown BJ, Band V, Band H, Kulak MV, Weigel RJ Abstract The AP-2gamma transcription factor, encoded by the TFAP2C gene, regulates the expression of estrogen recept

  pubmed: her2-positive breast...

  Fri Oct 18, 2019 04:51
• PD-1-Associated Gene Expression Signature of Neoadjuvant Trastuzumab-Treated Tumors Correlates with Patient Survival in HER2-Positive Breast Cancer.

  Related ArticlesPD-1-Associated Gene Expression Signature of Neoadjuvant Trastuzumab-Treated Tumors Correlates with Patient Survival in HER2-Positive Breast Cancer. Cancers (Basel). 2019 Oct 15;11(10): Authors: Hendricks WPD, Briones N, Halperin RF, Facista S, Heaton PR, Mahadevan D, Kim S Abstract The therapeutic HER2-targeting antibody trastuzumab has been shown to elicit tumor immune response in a

  pubmed: her2-positive breast...

  Fri Oct 18, 2019 04:51
• Emerging targets for cough therapies; NK1 receptor antagonists.

  Related ArticlesEmerging targets for cough therapies; NK1 receptor antagonists. Pulm Pharmacol Ther. 2019 Oct 14;:101853 Authors: Badri H, Smith JA Abstract Cough is mediated by vagal afferent fibres innervating the larynx and proximal airways. Pre-clinical studies suggest that vagal C fibres produce Substance P, one of the tachykinin family of neuropeptides, which has been shown to enhance cough via

  Larynx

  Fri Oct 18, 2019 04:49
• Management of Vocal Fold Paralysis and Dysphagia for Neurologic Malignancies in Children.

  Related ArticlesManagement of Vocal Fold Paralysis and Dysphagia for Neurologic Malignancies in Children. Ann Otol Rhinol Laryngol. 2019 Nov;128(11):1019-1022 Authors: Nagy P, Beckmann N, Cox S, Sheyn A Abstract OBJECTIVES: To evaluate our experience with a significant number of brain malignancy-related vocal fold paralysis patients and their response to vocal cord-related therapies. BACKGRO

  Larynx

  Fri Oct 18, 2019 04:49
• Type I Posterior Glottic Stenosis: Natural History and In-Office Management.

  Related ArticlesType I Posterior Glottic Stenosis: Natural History and In-Office Management. Ann Otol Rhinol Laryngol. 2019 Nov;128(11):1073-1077 Authors: Silva Merea V, Sadoughi B Abstract OBJECTIVES: To review the natural history of type I posterior glottic stenosis (PGS-I) and its treatment outcomes through a case presentation and demonstrate the feasibility of in-office management of PGS-I.

  Larynx

  Fri Oct 18, 2019 04:49
• Antibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression.

  Related ArticlesAntibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression. Cancer Med. 2018 05;7(5):2003-2012 Authors: Kaur K, Saxena A, Debnath I, O'Brien JL, Ajami NJ, Auchtung TA, Petrosino JF, Sougiannis AJ, Depaep S, Chumanevich A, Gummadidala PM, Omebeyinje MH, Banerjee S, Chatzistamou I, Chakraborty P, Fayad

  Larynx

  Fri Oct 18, 2019 04:49
• upper respiratory tract infection; +41 new citations

  41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/10/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

  Upper respiratory tract infection

  Fri Oct 18, 2019 04:34
• Recent advances from metabolomics and lipidomics application in alzheimer's disease inspiring drug discovery.

  Related ArticlesRecent advances from metabolomics and lipidomics application in alzheimer's disease inspiring drug discovery. Expert Opin Drug Discov. 2019 Oct 16;:1-13 Authors: Cuperlovic-Culf M, Badhwar A Abstract Introduction: Although age is a major risk factor for Alzheimer's disease (AD), it is not an inevitable consequence of aging nor is it exclusively an old-age disease. Several other major

  Expert Opinion on Drug Discovery

  Fri Oct 18, 2019 04:29
• Initial treatment of pediatric differentiated thyroid cancer: a review of the current risk-adaptive approach.

  Related ArticlesInitial treatment of pediatric differentiated thyroid cancer: a review of the current risk-adaptive approach. Pediatr Radiol. 2019 Oct;49(11):1391-1403 Authors: Parisi MT, Khalatbari H, Parikh SR, Alazraki A Abstract Differentiated thyroid cancer in children is a rare disease, accounting for only 1.4% of all pediatric malignancies. The diagnosis, biological behavior and treatment of d

  radioactive iodine

  Fri Oct 18, 2019 04:28
• Metabolic trade-offs hide unforeseen benefits of plasmids carriage [NEW RESULTS] Microbes can...

  Metabolic trade-offs hide unforeseen benefits of plasmids carriage [NEW RESULTS]Microbes can preserve plasmids in non-selective conditions, paying a metabolic cost---reduced growth rate---without getting any benefit from them. Explaining this paradox is challenging. Here I report that plasmids can change multiple traits simultaneously, making them unexpectedly beneficial. A competition between two identical Escherichia coli strains, S and R, wher

  www Αλέξανδρος Γ. Σφακιανάκης

  Sun Oct 20, 2019 02:44
• Effects of substrate and phylogeny on quadrupedal gait in free‐ranging platyrrhines

  Abstract Objectives Primate diagonal sequence (DS) gaits are often argued to be an adaptation for moving and foraging in the fine‐branch niche; however, existing data have come predominantly from laboratory studies that are limited in taxonomic breadth and fail to account for the structural and ecological variation of natural substrates. We test the extent to which substrate diameter and orientation influence gait sequence type and limb phase

  American Journal of Physical Anthropology

  Fri Oct 18, 2019 01:37
• Current status of biomarker testing in historically rare, high-unmet-need tumors: soft tissue sarcomas and thyroid cancers.

  Related ArticlesCurrent status of biomarker testing in historically rare, high-unmet-need tumors: soft tissue sarcomas and thyroid cancers. Expert Rev Anticancer Ther. 2019 Oct 17;: Authors: Schroader B, Kong SX, Anderson S, Williamson T, Sireci A, Shields K Abstract INTRODUCTION: The development of precision medicine and targeted therapies have revolutionized cancer treatment. Historically, treatmen

  pubmed: expert review of ant...

  Fri Oct 18, 2019 04:24
• GCMS analysis of sadagura (smokeless tobacco), its enhanced genomic instability causing potential due to arsenic co-exposure, and vitamin-C supplementation as a possible remedial measure: a study involving multiple model test systems.

  Related ArticlesGCMS analysis of sadagura (smokeless tobacco), its enhanced genomic instability causing potential due to arsenic co-exposure, and vitamin-C supplementation as a possible remedial measure: a study involving multiple model test systems. Drug Chem Toxicol. 2019 Oct 17;:1-12 Authors: Das S, Upadhaya P, Barhoi D, Nath Barbhuiya S, Langthasa P, Giri S Abstract North-eastern states of India,

  pubmed: "drug chem toxicol"[...

  Fri Oct 18, 2019 04:23
• In vitro cytogenetic activity of 3-amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide.

  Related ArticlesIn vitro cytogenetic activity of 3-amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide. Drug Chem Toxicol. 2019 Oct 17;:1-6 Authors: Atlı Şekeroğlu Z, Gediz Ertürk A, Kontaş Yedier S, Şekeroğlu V Abstract In a previous study, 3-amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide (DPTD), which is five-membered cyclosulfamide, was synthesi

  pubmed: "drug chem toxicol"[...

  Fri Oct 18, 2019 04:23
• Comprehensive analysis of the long noncoding RNA expression profile and construction of the lncRNA-mRNA co-expression network in colorectal cancer.

  Related ArticlesComprehensive analysis of the long noncoding RNA expression profile and construction of the lncRNA-mRNA co-expression network in colorectal cancer. Cancer Biol Ther. 2019 Oct 16;:1-13 Authors: Zhang Q, Ding Z, Wan L, Tong W, Mao J, Li L, Hu J, Yang M, Liu B, Qian X Abstract Long noncoding RNAs (lncRNAs) have been shown to play important roles in various tumors including colorectal can

  http://goo.gl/0msigD,Cancer biology and therapy

  Fri Oct 18, 2019 04:20
• Effect of Epilepsy and Antiepileptic Drugs Therapy on Erythrocyte Malondialdehyde and Some Antioxidants in Persons with Epilepsy.

  Related ArticlesEffect of Epilepsy and Antiepileptic Drugs Therapy on Erythrocyte Malondialdehyde and Some Antioxidants in Persons with Epilepsy. West Afr J Med. 2019 Sep-Dec;36(3):211-216 Authors: Iwuozo EU, Obiako OR, Ejiofor JI, Kehinde JA, Abubakar SA Abstract BACKGROUND: Antiepileptic drugs are necessary for successful treatment of epilepsy. Unfortunately, epilepsy itself and some antiepileptic

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Toward a Better Understanding of Neuronal Migration Deficits in Autism Spectrum Disorders.

  Related ArticlesToward a Better Understanding of Neuronal Migration Deficits in Autism Spectrum Disorders. Front Cell Dev Biol. 2019;7:205 Authors: Pan YH, Wu N, Yuan XB Abstract Newborn neurons in developing brains actively migrate from germinal zones to designated regions before being wired into functional circuits. The motility and trajectory of migrating neurons are regulated by both extracellula

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Levetiracetam induced hypomania: a case report.

  Related ArticlesLevetiracetam induced hypomania: a case report. Ther Adv Drug Saf. 2019;10:2042098619876754 Authors: Altınöz AE, Tosun Altınöz Ş, Güzel Biltekin B, Can Kaya M Abstract Levetiracetam (LEV) is a newer second-generation antiepileptic drug that is found to be effective in tonic-clonic seizures, partial onset seizures, and myoclonic seizures. Among antiepileptic drugs, LEV is usually known

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Investigating imaging network markers of cognitive dysfunction and pharmacoresistance in newly diagnosed epilepsy: a protocol for an observational cohort study in the UK.

  Related ArticlesInvestigating imaging network markers of cognitive dysfunction and pharmacoresistance in newly diagnosed epilepsy: a protocol for an observational cohort study in the UK. BMJ Open. 2019 Oct 16;9(10):e034347 Authors: de Bézenac C, Garcia-Finana M, Baker G, Moore P, Leek N, Mohanraj R, Bonilha L, Richardson M, Marson AG, Keller S Abstract INTRODUCTION: Epilepsy is one of the most common

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Communication Challenges: A Spotlight on New-Onset Refractory Status Epilepticus.

  Related ArticlesCommunication Challenges: A Spotlight on New-Onset Refractory Status Epilepticus. Mayo Clin Proc. 2019 05;94(5):857-863 Authors: Gofton TE, Wong N, Hirsch LJ, Hocker SE Abstract New-onset refractory status epilepticus (NORSE) is a rare, potentially devastating condition that occurs abruptly in previously healthy patients of any age but most commonly in children and young adults. It ha

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Design, synthesis and anticonvulsant evaluation of fluorinated benzyl amino enaminones.

  Related ArticlesDesign, synthesis and anticonvulsant evaluation of fluorinated benzyl amino enaminones. Bioorg Med Chem. 2019 01 01;27(1):161-166 Authors: Apraku J, Okoro CO Abstract Inspite of progress made for the discovery of novel antiepileptic drugs, epilepsy remains an unmet medical need. We synthesized nine trifluoromethylated enaminone derivatives and tested them for their anticonvulsant acti

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures.

  Related ArticlesComplex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures. Sci Rep. 2018 07 03;8(1):9986 Authors: Quinlan SMM, Rodriguez-Alvarez N, Molloy EJ, Madden SF, Boylan GB, Henshall DC, Jimenez-Mateos EM Abstract Seizures in neonates, mainly caused by hypoxic-ischemic encephalopathy, are thought to be harmful to the brain. Phenobarbital remains the first

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Variability and bias between magnetoencephalography systems in non-invasive localization of the primary somatosensory cortex.

  Related ArticlesVariability and bias between magnetoencephalography systems in non-invasive localization of the primary somatosensory cortex. Clin Neurol Neurosurg. 2018 08;171:63-69 Authors: Bardouille T, Power L, Lalancette M, Bishop R, Beyea S, Taylor MJ, Dunkley BT Abstract OBJECTIVES: Magnetoencephalography (MEG) provides functional neuroimaging data for pre-surgical planning in patients with ep

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Risk of Unnatural Mortality in People With Epilepsy.

  Related ArticlesRisk of Unnatural Mortality in People With Epilepsy. JAMA Neurol. 2018 08 01;75(8):929-938 Authors: Gorton HC, Webb RT, Carr MJ, DelPozo-Banos M, John A, Ashcroft DM Abstract Importance: People with epilepsy are at increased risk of mortality, but, to date, the cause-specific risks of all unnatural causes have not been reported. Objective: To estimate cause-specific unnatural

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Topiramate-Induced Chest Pain: A Case Report.

  Related ArticlesTopiramate-Induced Chest Pain: A Case Report. J Pharm Pract. 2019 Apr;32(2):236-239 Authors: Ostroff JL, LeClair Barnet JN, Ostroff ML, Laskey CS Abstract BACKGROUND: Topiramate, an anticonvulsant used for prophylaxis of migraines and epilepsy, is commonly associated with adverse effects of cognitive dulling and fatigue. Chest pain is a potential adverse effect that to our knowledge h

  pubmed: epilepsy treatment

  Fri Oct 18, 2019 04:19
• Pulsed Nd:YAG laser: effects on pain, postural stability, and weight-bearing pattern in children with hemophilic ankle arthropathy

  Abstract Hemophilic ankle arthropathy features joint pain, impaired postural control, and abnormal weight-bearing pattern. This study was designed to investigate the effects of pulsed Nd:YAG laser on pain, postural stability, and weight-bearing pattern in children with hemophilic ankle arthropathy. Forty children diagnosed with hemophilia type A (age, 8–16 years) were randomly allocated to either the treatment group (n = 20) wh

  Laser

  Thu Oct 17, 2019 17:00
• Placenta-specific protein 8 promotes the proliferation of lung adenocarcinoma PC-9 cells and their tolerance to an epidermal growth factor receptor tyrosine kinase inhibitor by activating the ERK signaling pathway.

  Related ArticlesPlacenta-specific protein 8 promotes the proliferation of lung adenocarcinoma PC-9 cells and their tolerance to an epidermal growth factor receptor tyrosine kinase inhibitor by activating the ERK signaling pathway. Oncol Lett. 2019 Nov;18(5):5621-5627 Authors: Zeng X, Liu Q, Yang Y, Jia W, Li S, He D, Ma R Abstract Placenta-specific protein 8 (PLAC8) is a conserved protein with a mole

  Oncology Letters

  Fri Oct 18, 2019 04:13
• Clinical significance of invasion distance relative to prognosis in pathological T3 colorectal cancer.

  Related ArticlesClinical significance of invasion distance relative to prognosis in pathological T3 colorectal cancer. Oncol Lett. 2019 Nov;18(5):5614-5620 Authors: Nomura M, Takahashi H, Fujii M, Miyoshi N, Haraguchi N, Hata T, Matsuda C, Yamamoto H, Mizushima T, Mori M, Doki Y Abstract The T3 subdivision has been reported to predict prognosis in rectal cancer. However, few studies describe a correl

  Oncology Letters

  Fri Oct 18, 2019 04:13
• The combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade.

  Related ArticlesThe combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade. Oncol Lett. 2019 Nov;18(5):5607-5613 Authors: Suo F, Zhong B, Lu F, Dong Z Abstract Glioma is the most aggressive brain tumor and is associated with a high mortality rate. The aim of the present study was to explore the association between matrix metalloproteinase 2 (

  Oncology Letters

  Fri Oct 18, 2019 04:13