Abstract Glioblastoma (GBM) of the spinal cord represents a rare entity in children and account for less than 1% of all central nervous system (CNS) cancers. Their biology, localization, and controversial treatment options have been discussed in a few pediatric cases. Here, we report a case of primary spinal cord glioblastoma in a 5-year-old girl having the particularity to be extended to the brainstem. This tumor has been revealed by torticollis and bilateral brachial paresis....
Wed Oct 30, 2019 02:00
Abstract Purpose Craniopharyngiomas remain a challenging entity for neurosurgeons because of their deep-seated, midline location, and intimate relationship with critical neurovascular structures. With high long-term survival rates, patients with craniopharyngioma are likely to experience significant late morbidity related to both disease and therapy. Method and results ...
Wed Oct 30, 2019 02:00
Abstract Minimally invasive fetal interventions require accurate imaging from inside the uterine cavity. Twin‐to‐twin transfusion syndrome (TTTS), a condition considered in this study, occurs from abnormal vascular anastomoses in the placenta that allow blood to flow unevenly between the fetuses. Currently, TTTS is treated fetoscopically by identifying the anastomosing vessels, and then performing laser photocoagulation. However, white light fetoscopy provides limited visibility of placental vasculature,...
Tue Oct 29, 2019 18:27
ABSTRACT The importance of T cells in immunotherapy has motivated developing technologies to improve therapeutic efficacy. One objective is assessing antigen‐induced T cell activation because only functionally active T cells are capable of killing the desired targets. Autofluorescence imaging can distinguish T cell activity states in a non‐destructive manner by detecting endogenous changes in metabolic co‐enzymes such as NAD(P)H. However, recognizing robust activity patterns is computationally challenging...
Tue Oct 29, 2019 18:15
Abstract We report onwide‐field time‐correlated single photon counting (TCSPC)‐based fluorescence lifetime imagingmicroscopy (FLIM) with lightsheet illumination.A pulsed diode laser is used for excitation, and a crossed delay line anode image intensifier, effectively a single‐photon sensitive camera, is used to record the position and arrival time of the photons with picosecond time resolution, combining low illumination intensity of microwattswith wide‐field data collection.We pair this detector...
Tue Oct 29, 2019 18:10
Related ArticlesAssociation of 25-hydroxyvitamin D with cardiometabolic risk factors and metabolic syndrome: a mendelian randomization study. Nutr J. 2019 Oct 28;18(1):61 Authors: Chen C, Chen Y, Weng P, Xia F, Li Q, Zhai H, Wang N, Lu Y Abstract BACKGROUND: Low circulating vitamin D levels have been associated with increased risk of metabolic syndrome (MS) and cardiometabolic risk factors in multiple epidemiology studies. However, whether this association...
Wed Oct 30, 2019 15:04
Publication date: Available online 29 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Buitron Gabriel, Kuzniar Marek
Wed Oct 30, 2019 15:02
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Ann Surg Oncol"[jour] These pubmed results were generated on 2019/10/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 30, 2019 14:59
40 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/10/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 30, 2019 14:58
39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2019/10/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 30, 2019 14:57
Related ArticlesA novel role mediated by adenoviral E1A in suppressing cancer through modulating decorin. Med Oncol. 2019 Oct 28;36(12):96 Authors: Ge Y, Zhang W, Qin J, Zhang C, Tian W, Zhang Q, Shao J, Li S, Fang L, Zheng J Abstract Oncolytic adenovirus is an emerging alternative to current therapeutics. The adenoviral E1A, the first protein expressed upon oncolytic adenoviral infection, has been identified as an antitumor agent, but the mechanisms...
Wed Oct 30, 2019 14:55
Related ArticlesThe safety and tolerability profile of bilastine for chronic urticaria in children. Clin Transl Allergy. 2019;9:55 Authors: Papadopoulos NG, Zuberbier T Abstract Background: Urticaria is a condition defined by the development of wheals, angioedema or both. It is classified based on its duration as acute (≤ 6 weeks) or chronic (> 6 weeks). Chronic urticaria is less frequent than acute one in children, but it represents a debilitating...
Wed Oct 30, 2019 14:51
Abstract Recent research efforts to identify genes involved in malaria susceptibility using genome-wide approaches have focused on severe malaria. Here, we present the first GWAS on non-severe malaria designed to identify genetic variants involved in innate immunity or innate resistance mechanisms. Our study was performed on two cohorts of infants from southern Benin (525 and 250 individuals used as discovery and replication cohorts, respectively) closely followed from birth to...
Wed Oct 30, 2019 02:00
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Reem Al Alawi, Mohamed Saiel Saeed Alhamdani, Jörg D. Hoheisel, Younis BaqiAbstractDate palm fruit (Phoenix dactylifera L.) is an endemic functional food, with great nutritional and economic importance due to its phytochemical compositions. The microenvironment of pancreatic cancer consists of cellular and acellular components, including fibroblasts, myofibroblasts, pancreatic stellate cells (PSCs), immune...
Wed Oct 30, 2019 14:46
Publication date: Available online 18 October 2019Source: Biomedicine & PharmacotherapyAuthor(s): Tinghong Ye, Shirui Zhu, Yongxia Zhu, Qiang Feng, Bing He, Yiong Xiong, Lifeng Zhao, Yiwen Zhang, Luoting Yu, Li Yang
Wed Oct 30, 2019 14:46
Publication date: Available online 16 October 2019Source: Biomedicine & PharmacotherapyAuthor(s): Fangfang Yang, Yang Yu, Qian Lei, Anqi Zeng, Yali Li, Yongmei Xie, TingHong Ye, Yuquan Wei
Wed Oct 30, 2019 14:46
Publication date: Available online 12 October 2019Source: Biomedicine & PharmacotherapyAuthor(s): Lingli Zheng, Lianhong Yin, Lina Xu, Yan Qi, Hua Li, Xu Youwei, Xu Han, Kexin Liu, Jinyong Peng
Wed Oct 30, 2019 14:46
Related ArticlesPrognostic value of CRTC1-MAML2 translocation in salivary mucoepidermoid carcinoma: systematic review and meta-analysis. J Oral Pathol Med. 2019 Oct 29;: Authors: Pérez-de-Oliveira ME, Wagner VP, Araújo ALD, Martins MD, Santos-Silva AR, Bingle L, Vargas PA Abstract The presence of the CRTC1-MAML2 translocation has been described in mucoepidermoid carcinoma (MEC) as a predictor of better survival rates. However, the real prognostic value...
Wed Oct 30, 2019 14:40
Related ArticlesTumor-infiltrating lymphocytes-derived MLL2 independently predicts disease-free survival for patients with early-stage oral squamous cell carcinoma. J Oral Pathol Med. 2019 Oct 29;: Authors: Zhu N, Ding L, Fu Y, Yang Y, Chen S, Chen W, Zhao M, Zhao X, Lu Z, Ni Y, Hu Q Abstract BACKGROUND: MLL2 (mixed-lineage leukemia 2) is recognized as an essential role in regulating histone 3 lysine 4 tri-methylation (H3K4me3) in mammalian cells. It...
Wed Oct 30, 2019 14:40
Related ArticlesApplication of Externally Applied Lower Punch Vibration and its Effects on Tablet Manufacturing. Pharm Res. 2019 Oct 28;36(12):173 Authors: Kalies A, Özcoban H, Leopold CS Abstract PURPOSE: In the present study the influence and application of a newly developed external lower punch vibration system for an improved die filling on a running rotary tablet press was investigated. METHODS: Tablets were manufactured at different conditions...
Wed Oct 30, 2019 14:31
Related ArticlesThrifty, Rapid Intestinal Monolayers (TRIM) Using Caco-2 Epithelial Cells for Oral Drug Delivery Experiments. Pharm Res. 2019 Oct 28;36(12):172 Authors: Lamson NG, Ball RL, Fein KC, Whitehead KA Abstract PURPOSE: Caco-2 monolayers are the most common model of the intestinal epithelium and are critical to the development of oral drug delivery strategies and gastrointestinal disease treatments. However, current monolayer systems are cost-...
Wed Oct 30, 2019 14:31
Abstract Purpose Respiratory inductive plethysmography (RIP) is recommended as an alternative respiratory sensor for the identification of each apnea and hypopnea event in polysomnography. Using this sensor, the cumulative RIP results from the chest and abdomen (RIP sum) and time-derived results of the RIP sum (RIP flow) are calculated to track respiratory flow. However, the effectiveness of this sensor and the calculated respiratory results...
Wed Oct 30, 2019 02:00
Abstract Objectives This study aimed to revisit benign odontogenic ghost cell lesions (BOGCL) by hematoxylin and eosin staining and immunohistochemistry. Materials and methods Thirty cases of calcifying odontogenic cyst (COC) and 6 cases of dentinogenic ghost cell tumor (DGCT) were selected for histopathological and immunohistochemical analysis....
Wed Oct 30, 2019 14:27
Abstract Obsessive‐compulsive disorder (OCD) is a psychiatric illness that significantly impacts affected patients, and available treatments yield suboptimal therapeutic response. Recently, the role of the gut‐brain axis (GBA) in psychiatric illness has emerged as a potential target for therapeutic exploration. However, studies concerning the role of the GBA in OCD are limited. To investigate whether a naturally occurring obsessive‐compulsive‐like phenotype in a rodent model, i.e. large nest‐building...
Tue Oct 29, 2019 18:14
Viroj WiwanitkitHeart and Mind 2018 2(4):95-97Thalassemia is an important congenital hemoglobin disorder. This disease can cause anemia and other systematic clinical problems including cardiac problem. The psychological problem due to congenital disorder among patients with thalassemia is also observable. Both cardiac and psychological problems should be well managed. There is an interrelationship between cardiac and psychological problems in thalassemic patients. The interdisciplinary management...
Wed Oct 30, 2019 00:00
Steven A Svoboda, Gurjot K Malhi, Anita S KablingerHeart and Mind 2018 2(4):119-121Catatonia is a psychomotor syndrome with poorly understood pathophysiology that frequently occurs concurrently with acute psychiatric and medical illnesses. Its prevalence among psychiatric inpatients has been reported to be as high as 38% and is primarily observed in those with mood disorders. Diagnosis requires the presence of at least three of the following signs: mutism, negativism, immobility, agitation, waxy...
Wed Oct 30, 2019 00:00
Annalijn I Conklin, Alex C T. Tam, Christopher A Yao, Sherry X R. Guo, Christopher G RichardsonHeart and Mind 2018 2(4):98-105Background: Cardiovascular diseases are a leading cause of death globally, and a major risk factor is obesity in early age groups. Obesity in children and youth is a growing public health concern, and inequalities exist across social groups. Evidence on ethnic disparities in obesity risk is mixed, and little is known about ethnicity and obesity in late adolescence. Moreover,...
Wed Oct 30, 2019 00:00
Colucci Roberto, Di Ionna Giuseppe, Cavezzi AttilioHeart and Mind 2018 2(4):111-118Background: Heart Rate Variability (HRV) is a parameter used to investigate the autonomous neural system (sympathetic and parasympathetic system). Reduced HRV is a risk factor which correlates with physical and psychological stress, psychoneuroendocrineimmunology dysregulation as well as with aging. HRV is considered a reliable parameter to investigate psycho-physical resilience, the latter being considered a key-factor...
Wed Oct 30, 2019 00:00
GK Mini, PS Sarma, KR ThankappanHeart and Mind 2018 2(4):106-110Background: In India, studies exploring the incidence rate of hypertension (HTN) are limited particularly among industrial workers. We estimated the incidence rate of HTN among industrial workers with and without pre-HTN during a 2-year follow period and the factors associated with incident HTN among industrial workers in Kerala, India. Materials and Methods: A total of 326 industrial workers (mean age: 51 years, men: 76%), from two...
Wed Oct 30, 2019 00:00
Alyson Pompeo-FargnoliHeart and Mind 2018 2(4):122-124In the evolving healthcare landscape, providers, patients, and insurers are seeking synergistic ways to improve quality and lower costs. The following presents the attainment of this synergy through a clinical case, illustrating proper patient diagnosis and care, as well as provider knowledge of best treatment practices. This specific case illustrates this through the management of a patient who recently experienced a cardiac event and subsequent...
Wed Oct 30, 2019 00:00
Related Articles[Innovative psychotherapy research: towards an evidence-based and process-based individualized and modular psychotherapy]. Nervenarzt. 2019 Oct 28;: Authors: Brakemeier EL, Herpertz SC Abstract Psychotherapy has been proven to be effective; however, this statement applies in particular to the "average patient" in randomized controlled trials. As a considerable proportion of patients do not show any benefits despite the constant development...
Wed Oct 30, 2019 14:05
Risk of Mortality between Untreated and Treated Papillary Thyroid Cancer: A Matched Cohort Analysis.
Related ArticlesRisk of Mortality between Untreated and Treated Papillary Thyroid Cancer: A Matched Cohort Analysis. Ann Otol Rhinol Laryngol. 2019 Oct 28;:3489419885403 Authors: Lin JK, Sakoda LC, Darbinian J, Socarras M, Chiao W, Calixto N, Quesenberry C, Gurushanthaiah D, Wang KH, Durr M Abstract OBJECTIVES: To examine the association between treatment status and mortality risk among patients with papillary thyroid cancer (PTC). METHODS:...
Wed Oct 30, 2019 14:04
Related ArticlesNeck Surgery with Hypnosis: An Evaluation Based Upon Patient's Self Assessment. Ann Otol Rhinol Laryngol. 2019 Oct 28;:3489419882445 Authors: Jaouen M, Parent V, Codet M, Gerard V, Chatellier-Miras A, Chaize C, De Crouy Chanel O, Jegoux F Abstract BACKGROUND: Surgery with hypnosis avoids the use of general anesthesia (GA). It also shortens hospitalization and promotes outpatient surgery. The objective of this study has been to assess...
Wed Oct 30, 2019 14:04
Publication date: Available online 29 October 2019Source: Clinical TherapeuticsAuthor(s): Tiffany M. Hopkins, Paul Juang, Katherine Weaver, Marin H. Kollef, Kevin D. BetthauserAbstractPurposeCurrent data suggest potential benefits with β-lactam plus macrolide combination therapy for empiric treatment of intensive care unit (ICU) patients with severe community-acquired pneumonia (CAP). However, it is unclear whether deescalation to β-lactam monotherapy in the absence of positive results on diagnostic...
Wed Oct 30, 2019 14:03
90 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/10/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 30, 2019 14:02
Related ArticlesMonte Carlo investigation of electron specific energy distribution in a single cell model. Radiat Environ Biophys. 2019 Oct 28;: Authors: Markovic VM, Stevanovic N, Nikezic D Abstract Knowledge of microdosimetric quantities of certain radionuclides is important in radio immune cancer therapies. Specific energy distribution of radionuclides, which are bound to the cell, is the microdosimetric quantity essential in the process of radionuclide...
Wed Oct 30, 2019 13:57
Related ArticlesRegional differences in endoscopic sinus surgery in Finland: a nationwide register-based study. BMJ Open. 2018 10 18;8(10):e022173 Authors: Toppila-Salmi S, Rihkanen H, Arffman M, Manderbacka K, Keskimaki I, Hytönen ML Abstract OBJECTIVES: Endoscopic sinus surgery (ESS) is a common operation typically performed due to chronic rhinosinusitis (CRS). There are limited data on the nationwide ESS rate and factors contributing to its regional...
Wed Oct 30, 2019 13:55
Related ArticlesEvaluating the accuracy of geometrical distortion correction of magnetic resonance images for use in intracranial brain tumor radiotherapy. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):606-613 Authors: Bagherimofidi SM, Yang CC, Rey-Dios R, Kanakamedala MR, Fatemi A Abstract Aim: Determine the 1) effectiveness of correction for gradient-non-linearity and susceptibility effects on both QUASAR GRID3D and CIRS phantoms; and 2) the magnitude...
Wed Oct 30, 2019 13:54
Related ArticlesComparison of patient-specific intensity modulated radiation therapy quality assurance for the prostate across multiple institutions. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):600-605 Authors: Kubo K, Monzen H, Shimomura K, Matsumoto K, Sato T, Tamura M, Nakamatsu K, Ishii K, Kawamorita R Abstract Aim: To evaluate the success of a patient-specific intensity modulated radiation therapy (IMRT) quality assurance (QA) practice for prostate...
Wed Oct 30, 2019 13:54
Related ArticlesMeasurement of percentage dose at the surface for a 6 MV photon beam. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):585-592 Authors: Galván De la Cruz OO, Rodríguez-Ávila MA, Rivera-Montalvo T, García Garduño OA Abstract Aim: To evaluate if a radiochromic film (RF) Gafchromic EBT3 is suitable for surface dose measurements of radiotherapy treatments performed with a 6 MV linear accelerator. Two aspects of RF were analyzed, beam energy...
Wed Oct 30, 2019 13:54
Related ArticlesFormulation of normal tissue irradiation volumes in Co-60 and Ir-192 HDR ICBT of Ca cervix using Total Reference Air Kerma (TRAK). Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):568-575 Authors: Robert N, Chauhan RP, Oinam A, Rai B Abstract Aim: The aim of this study was to formulate isodose volume relations encompassed by isodose surfaces in Co-60 and Ir-192 HDR intracavitary brachytherapy (ICBT) of cervix carcinoma using the Total Reference...
Wed Oct 30, 2019 13:54
Related ArticlesSkin barrier function in patients under radiation therapy due to the head and neck cancers - Preliminary study. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):563-567 Authors: Pazdrowski J, Polaſska A, Kaźmierska J, Barczak W, Szewczyk M, Adamski Z, Żaba R, Golusiſski P, Golusiſski W, Daſczak-Pazdrowska A Abstract Aim: To present the possibility of non-invasive monitoring of the skin after radiotherapy in regards of epidermal barrier function....
Wed Oct 30, 2019 13:54
Related ArticlesChanges in lung volume parameters regarding the received dose in the lobes of the lungs after locoregional radiotherapy of breast cancer. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):556-562 Authors: Abdemanafi M, Tavakoli MB, Akhavan A, Abedi I Abstract Aim: The purpose of this study was to evaluate ΔLVP and correlate them with MLD and V20 in the lobes of the lung. Background: Radiation-induced lung injury after breast irradiation...
Wed Oct 30, 2019 13:54
Related ArticlesIntraoperative breast radiotherapy: survival, local control and risk factors for recurrence. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):551-555 Authors: Gondim GRM, Makdissi FBA, Fogaroli RC, Collins JBD, Iyeyasu H, de Castro DG, Silva MLG, Chen MJ, Coelho TM, Ramos H, Pellizzon ACA Abstract Background: Whole breast irradiation reduces loco-regional recurrence and risk of death in patients submitted to breast-conserving treatment....
Wed Oct 30, 2019 13:54
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