Abstract Objectives Although many physicians in daily practice assume a connection between odontogenic infections and meteorological parameters, this has not yet been scientifically proven. Therefore, the aim of the present study was to evaluate the incidence of odontogenic abscess (OA) in relation to outdoor temperature and atmospheric pressure. Patients and methods...
Abstract Objective To assess the effectiveness of atraumatic restorative treatment (ART) performed 4 years ago in babies suffering from early childhood caries (ECC), and to compare the clinical performance of ART atraumatic restorations performed with two different high-viscosity glass ionomer cements (GIC). Materials and methods This was a...
Abstract Objectives The aim of this in vitro study was to assess changes in the gene expression of proinflammatory cytokines in human whole blood after contact with titanium implant surfaces conditioned by UV light. To this end, expression levels of proinflammatory cytokines were analyzed in vitro in human whole blood. Materials and methods ...
Abstract Objectives A systematic review and meta-analysis were performed to answer this research question: “Does combined in-office (IO) and at-home (AH) bleaching produce improved color change and lower tooth sensitivity (TS) better than solely AH or IO bleaching in adults?” Material and methods Randomized controlled trials in adults that compared...
Abstract Objectives The objective of the study is to assess, by clinical follow-up, the efficacy of the dermatological cream Fludroxycortide 0.125 mg/g (Drenison®) in the treatment of actinic cheilitis (AC). Material and methods Twenty-three patients diagnosed with AC participated in the study. Fifteen were submitted to corticotherapy with Fludroxycortide,...
Abstract Objectives To assess in persons aged 70 years or older the microbiological alterations occurring around implants and natural teeth during and after 3 weeks of undisturbed plaque accumulation. Furthermore, to test the predictive value of several markers at baseline for the extent of inflammation around implants and teeth after this period. Materials and methods...
Abstract Objectives This study assessed the frequency of nuclear morphological changes in gingival epithelial cells, as a biomarker for DNA damage, in individuals with periodontitis, before and after implementation of periodontal therapy, and compared the morphology to those with healthy periodontal tissues. Materials and methods Exfoliated...
Abstract Objective To assess the radiographic pattern of underlying dentine shadows (UDS) in the occlusal surfaces of permanent teeth. Methods A total of 282 permanent posterior teeth pertaining to 91 individuals, 142 UDS and 140 non-cavitated enamel lesions (NCEL), were included for comparison. UDS was defined as shadows of discolored dentin...
Abstract Objective The aim of this study was to analyze the biological effects of MTA Repair HP and ProRoot MTA on human periodontal ligament stem cells (hPDLSCs) after exposure to acidic and neutral environments. Materials and methods Discs of each material (n = 30) were exposed to phosphate buffered saline (pH = 7.4) or butyric acid (pH = 5.2)...
Abstract Objectives This study aimed to assess self- and proxy-rated changes in the oral health-related quality of life (OHRQoL) in adult patients with intellectual disabilities after dental treatment in general anesthesia. Methods The OHRQoL in 52 adult patients with intellectual and developmental disabilities was assessed prior to dental treatment...
Abstract Objectives To examine associations between periodontal disease severity and clinical and microbiological measures of caries in adults. Materials and methods A cross-sectional study of 94 healthy adults ((mean ± SD) 55.4 ± 13.0 years) was conducted. Data were collected by means of questionnaire and a clinical examination that included...
Abstract Objectives Tumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters. Materials and methods ...
Abstract Objectives The aim of this murine in vivo study was to investigate whether buffy coat–derived putative endothelial progenitor cells (BCEPC) alter tumor growth and neovascularization in oral squamous cell carcinomas (OSCC). Materials and methods A murine xenograft model using the PCI-13 oral cancer cell line was deployed of which n = 24...
Abstract Objectives The aim of this study was to investigate the predictive value of the biomarkers FHIT, p27, and pERK1/ERK2 in salivary gland carcinomas. Material and methods Immunohistochemical staining of FHIT, p27, and pERK1/ERK2 of 265 patients with salivary gland carcinomas was conducted, and associations with clinico-histopathological...
Publication date: Available online 15 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Saiji Shimoe, Tzu-Yu Peng, Mai Otaku, Nozomi Tsumura, Shogo Iwaguro, Takahiro SatodaAbstractStatement of problemIndirect composite resins (ICRs) have been suggested as veneering materials for implant-supported zirconia-based fixed dental prostheses; however, obtaining a durable bond between the zirconia ceramic and the ICR is a challenge.PurposeThe purpose of this in vitro study was to evaluate...
Publication date: Available online 15 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Yunyi Xie, Enbao He, Zeyuan Cao, Qianmin Ou, Yan WangAbstractStatement of problemPolyvinylphosphonic acid (PVPA) could be used as a biomimetic remineralization analog and a matrix metalloproteinases (MMPs) inhibitor. However, studies are lacking regarding the performance of PVPA in dental bonding systems for maintaining the durability of the resin-dentin bond.PurposeThe purpose of this in vitro...
Abstract Background Oral submucous fibrosis (OSF) is a chronic progressive oral disease with cancerous tendency. Arecoline plays an important role in the pathogenesis of OSF. Fibroblasts (FBs) are the primary cells involved in the pathogenesis of OSF. There is a change in CD4+IL‐17+ helper T cells (Th17) and CD4+CD25+Foxp3+ regulatory T cells (Treg) in OSF patients, but the molecular mechanisms of are not clearly understood. In this work, we studied the molecular mechanisms. Methods Enzyme...
Abstract Objectives The aim of this study was to evaluate the accuracy of complete‐arch digital impressions for fabrication of an implant‐supported prosthesis in the edentulous maxilla using an auxiliary geometry part. Material and Methods A replica of the upper jaw of an edentulous patient with four scannable impression copings was fabricated in stainless steel. This model was scanned with an industrial non‐contact 3D structured blue light 3D scanner and the measurements of three reference...
Abstract Objective This study aimed to evaluate the precision of digital implant impressions in comparison with conventional impressions and assess the impact of the scanning range on precision. Materials and Methods An edentulous maxilla model with six implants was scanned with four intraoral scanners (IOSs) and a dental laboratory scanner five times each, and stereolithography (STL) data were generated. A conventional silicone impression was made and a model was fabricated, which was...
The purpose of this study was to compare the condylar positional changes after bilateral sagittal split ramus osteotomy (BSSRO) in patients with mandibular retrusion and those with mandibular prognathism. We also studied the correlation between the degree of matching of the condyle and fossa, and condylar displacement. Thirty patients with mandibular retrusion (n=11) or mandibular prognathism (n=19) who underwent BSSRO were included. The condylar position was assessed from spiral computed tomographic...
Abstract Background Clinical evidence of the autologous platelet concentrates effects on the patient-reported outcome measures (PROMs) after endodontic surgery is still limited. Objectives To investigate the effect of the advanced platelet-rich fibrin (A-PRF+) membrane application upon patient postoperative pain, and quality of life in endodontic surgery....
Publication date: Available online 12 October 2019Source: Archives of Oral BiologyAuthor(s): Mpho Sebelemetja, Sharon Moeno, Mrudula PatelAbstractObjectiveDental caries is caused by plaque associated oral bacteria including a pioneer species Streptococcus mutans. It has ability to form biofilm and produce acids in the oral cavity. Many oral hygiene products containing plant derived compounds have been investigated for their anti-S. mutans activity. Dodonaea viscosa var. angustifolia (DVA), has been...
This is the third of three articles that give an overview of the current evidence for management of the neck and parotid in patients with cutaneous cancers of the head and neck. In this paper we discuss Merkel cell carcinoma (MCC) and review the latest evidence for management of the regional nodes.
After their initial presentation of oral squamous cell carcinoma (SCC), patients have a lifelong risk of developing another new SCC of the head and neck. The aim of this study was to establish second primary rates, baseline characteristics (site, clinical or pathological stage, and smoking and alcohol history), timing, presentation, treatment, and outcomes. From the regional unit we analysed records of patients treated with curative intent for their first oral cancer between 2002 and 2007 inclusive.
One in 16 patients prescribed opioids after a surgical procedure will become a long-term user. The lack of procedure-specific guidelines after common dental procedures contributes to the opioid overprescribing problem. We convened a multidisciplinary panel to develop consensus recommendations for opioid prescribing after common dental procedures. We used a three-step modified Delphi method to develop a consensus recommendation for outpatient opioid prescribing for 14 common dental procedures. The...
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