Related ArticlesPresentation and Management of Killian Jamieson Diverticulum: A Comprehensive Literature Review. Ann Otol Rhinol Laryngol. 2019 Nov 09;:3489419887403 Authors: Haddad N, Agarwal P, Levi JN, Tracy JC, Tracy LF Abstract OBJECTIVE: To examine the clinical presentation, diagnostic evaluation, and management of Killian-Jamieson diverticula (KJD) through literature review. METHODS: A comprehensive literature review was conducted through...
Tue Nov 12, 2019 14:28
Related ArticlesIntravascular Papillary Endothelial Hyperplasia of the Vocal Cord: A Case Report and Review of the Literature. Am J Case Rep. 2019 Nov 12;20:1664-1668 Authors: Shim HK, Kim MR Abstract BACKGROUND Intravascular papillary endothelial hyperplasia (IPEH), is a vascular tumor characterized by the proliferation of endothelial cells with papillary formations. It is a rare benign disease; therefore, it is important to exclude malignant vascular...
Wed Nov 13, 2019 19:20
Related ArticlesUnusual Pattern of Invasive Lobular Carcinoma Metastasis: A Case Report. Am J Case Rep. 2019 Nov 11;20:1659-1663 Authors: Kachi A, Nicolas G, Semaan DB, Hashem M, Abou Sleiman C Abstract BACKGROUND Metastasis of breast cancer to the gastrointestinal (GI) tract is not common, however, invasive lobular carcinoma is more likely to metastasize to the GI tract than ductal carcinoma. The simultaneous metastasis of invasive lobular carcinoma...
Tue Nov 12, 2019 14:31
22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Front Oncol"[jour] These pubmed results were generated on 2019/11/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Nov 12, 2019 17:52
22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Front Oncol"[jour] These pubmed results were generated on 2019/11/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Nov 12, 2019 13:56
Bipolar clavicular fracture on ipsilateral reverse shoulder prosthesis: Case report. Int J Surg Case Rep. 2019 Nov 03;65:176-179 Authors: Maalouly J, Aouad D, Saade J, Abboud G, El Rassi G Abstract BACKGROUND: Bipolar clavicular fractures are extremely rare with no consensus on management. No previous cases of bipolar clavicular fracture on an ipsilateral reverse shoulder prosthesis have been reported. CASE PRESENTATION: We report a case of...
Wed Nov 13, 2019 19:40
Acute purulent mediastinitis with sequential bilateral pleural empyema caused by neck trauma: A unique occurrence, a case report. Int J Surg Case Rep. 2019 Nov 03;65:171-175 Authors: Davoodabadi A, Entezari H, Talari H, Razi E Abstract BACKGROUND: Descending necrotizing mediastinitis (DNM) due to blunt trauma is very rare form of mediastinitis that can rapidly progress to septicemia and multi organ failure, in spite of optimal surgical management. ...
Wed Nov 13, 2019 19:40
Atraumatic splenic rupture in young adult following cocaine use. Int J Surg Case Rep. 2019 Nov 03;65:168-170 Authors: Lee Ramos J, Farr M, Shin SH, Ahmed N Abstract INTRODUCTION: Splenic rupture most commonly results from a traumatic mechanism. Spontaneous splenic ruptures are a rare occurrence. This is an interesting and rare case of atraumatic splenic rupture (ASR) presented after sniffing cocaine. PRESENTATION OF CASE: The patient presented...
Wed Nov 13, 2019 19:40
A case report of esophageal heterotopic pancreas presenting as recurrent mediastinal abscess, treated by minimally invasive esophagectomy. Int J Surg Case Rep. 2019 Oct 23;65:164-167 Authors: Bianchi ET, Tustumi F, Fonseca Duarte A, Ortiz ES, Szachnowicz S, da Costa Seguro FCB, Aissar Sallum RA, Cecconello I Abstract INTRODUCTION: Heterotopic pancreas is a rare congenital anomaly. We report a case of esophageal heterotopic pancreas complicated by recurrent...
Wed Nov 13, 2019 19:40
A case of spontaneous mesenteric hematoma successfully diagnosed and treated with aggressive imaging. Int J Surg Case Rep. 2019 Oct 31;65:124-126 Authors: Nakamura S, Yamada T, Nojima T, Naito H, Koga H, Yamashita H, Gochi A, Nakao A Abstract INTRODUCTION: Spontaneous mesenteric hematoma is an uncommon syndrome triggered by bleeding localized in the mesenteric vascular tree of a bowel segment for no apparent underlying reason. We herein report a surgical...
Wed Nov 13, 2019 19:40
Related ArticlesA rare case of incidental finding of GIST during sleeve gastrectomy: Case report. Int J Surg Case Rep. 2019 Nov 01;65:161-163 Authors: Ayoub K, Danial AK, Sankari Tarabishi A, Shebli B, Halwani MY, Mahli N Abstract INTRODUCTION: Gastrointestinal stromal tumors (GISTs) is the term used to describe rare stromal neoplasms that are located in the gastrointestinal tract, it most commonly arises in the stomach. GIST is usually asymptomatic...
Tue Nov 12, 2019 17:42
Related ArticlesSevere late dysphagia after multimodal treatment of stage III/IV laryngeal and hypopharyngeal cancer. Jpn J Clin Oncol. 2019 Nov 11;: Authors: Huh G, Ahn SH, Suk JG, Lee MH, Kim WS, Kwon SK, Ock CY, Keam B, Heo DS, Kim JH, Wu HG Abstract BACKGROUND: Long-term side effects after radiotherapy for organ preservation 'could deteriorate' the laryngeal function. This study intended to identify the incidence of severe late dysphagia following...
Tue Nov 12, 2019 17:00
Related ArticlesPrognosis viewing for nasopharyngeal carcinoma treated with intensity-modulated radiation therapy: application of nomogram and decision curve analysis. Jpn J Clin Oncol. 2019 Nov 11;: Authors: Fei Z, Qiu X, Li M, Chen C, Li Y, Huang Y Abstract OBJECTIVE: To view and evaluate the prognosis factors in patients with nasopharyngeal carcinoma (NPC) treated with intensity modulated radiation therapy using nomogram and decision curve analysis...
Tue Nov 12, 2019 17:00
Related ArticlesPHQ-9 and SNOT-22: Elucidating the Prevalence of Depression in Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2019 Nov 12;:194599819886852 Authors: Vandelaar LJ, Jiang ZY, Saini A, Yao WC, Luong AU, Citardi MJ Abstract OBJECTIVE: Chronic rhinosinusitis (CRS) has been associated with comorbid depression, yet the prevalence of depression among all patients with CRS is not well described. The Patient Health Questionnaire-9 (PHQ-9),...
Wed Nov 13, 2019 20:32
Related ArticlesSafety of Conservative Approach for Persistent Patent Ductus Arteriosus in Preterm Infants: Neurodevelopmental Outcomes at 5 Years of Age. Tohoku J Exp Med. 2019;249(3):155-161 Authors: Kaga M, Sanjo M, Sato T, Miura Y, Ono T Abstract Patent ductus arteriosus (PDA) is a common problem among preterm infants. The standard of care for PDA has been to attempt to close the PDA by pharmacological treatment or surgical ligation. Recently, conservative...
Tue Nov 12, 2019 15:21
Related ArticlesLow Bone Mineral Density of the Forearm and Femur among Postmenopausal Women with Metaphyseal Comminuted Fracture of the Distal Radius. Tohoku J Exp Med. 2019;249(3):147-154 Authors: Kanda T, Endo N, Kondo N Abstract Osteoporosis is characterized by bone loss and skeletal fragility and is likely to occur in postmenopausal women. Distal radius fracture is a type of fragility fractures associated with osteoporosis. Bone mineral density...
Tue Nov 12, 2019 15:21
Related ArticlesAuthors' Reply: Honorary Authorships in Surgical Literature. World J Surg. 2019 Nov 11;: Authors: Luiten JD, Gadjradj PS PMID: 31712847 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 21:00
Related ArticlesObesity is Associated with Worse Outcomes Among Abdominal Trauma Patients Undergoing Laparotomy: A Propensity-Matched Nationwide Cohort Study. World J Surg. 2019 Nov 11;: Authors: Fu CY, Bajani F, Bokhari M, Tatebe LC, Starr F, Messer T, Kaminsky M, Dennis A, Schlanser V, Mis J, Toor R, Poulakidas S, Bokhari F Abstract INTRODUCTION: Obesity is associated with increased morbidity and mortality in abdominal trauma patients. The characteristics...
Wed Nov 13, 2019 21:00
Related ArticlesAmoebic Liver Abscesses in Fiji: Epidemiology, Clinical Presentation and Comparison of Percutaneous Aspiration and Percutaneous Catheter Drainage. World J Surg. 2019 Nov 11;: Authors: Vakamacawai E, McCaig E, Waqainabete I, Cox MR Abstract BACKGROUND: Amoebic liver abscess (ALA) is a common clinical problem in tropical countries related to poor sanitation. The epidemiology and clinical presentation of ALA in Fiji has not been previously...
Wed Nov 13, 2019 21:00
Related ArticlesThe Effect of Resection Margin Distance and Invasive Component Size on Recurrence After Sublobar Resection in Patients With Small (≤2 Cm) Lung Adenocarcinoma. World J Surg. 2019 Nov 11;: Authors: Moon Y, Park JK, Lee KY Abstract BACKGROUND: When performing sublobar resection for lung cancer, the margin distance should exceed the tumor size. However, instead of total tumor size, the 8th edition TNM staging system has adopted the size of...
Wed Nov 13, 2019 21:00
Related ArticlesDevelopment of a Visual Analytics Tool for Polytrauma Patients: Proof of Concept for a New Assessment Tool Using a Multiple Layer Sankey Diagram in a Single-Center Database. World J Surg. 2019 Nov 11;: Authors: Mica L, Niggli C, Bak P, Yaeli A, McClain M, Lawrie CM, Pape HC Abstract INTRODUCTION: Early physiological assessment of multiple injured patients is crucial for decision making and has relied on personal experience of trauma experts....
Wed Nov 13, 2019 21:00
Related ArticlesStepwise Approach for Parathyroid Localisation in Primary Hyperparathyroidism. World J Surg. 2019 Nov 11;: Authors: Korwar V, Yuen Chang F, Teasdale E, Suchett-Kaye I, Edwards A, Morgan J Abstract INTRODUCTION: Primary hyperparathyroidism (PHPT) is a relatively common condition in surgical practice. Availability of localisation studies has shifted the treatment from bilateral neck exploration to selective parathyroidectomy. Several imaging...
Wed Nov 13, 2019 21:00
Surgeon-Performed Vacuum-Assisted Biopsy of the Breast: Results from a Multicentre Australian Study.
Related ArticlesSurgeon-Performed Vacuum-Assisted Biopsy of the Breast: Results from a Multicentre Australian Study. World J Surg. 2019 Nov 11;: Authors: Bennett I, de Viana D, Law M, Saboo A Abstract BACKGROUND: Image-guided interventional techniques such as vacuum-assisted biopsy are being increasingly utilised in the diagnosis and management of breast conditions. The purpose of this study was to report the outcome of a series of vacuum-assisted biopsies...
Wed Nov 13, 2019 21:00
The concept of spectrobiopsy facing to gliomas: rational and future perspectives related to target therapy. World Neurosurg. 2019 Nov 09;: Authors: Torregrossa F, Grasso G PMID: 31715420 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 20:07
Atypical cauda equina syndrome with lower limb clonus: a literature review and case report. World Neurosurg. 2019 Nov 09;: Authors: Mirza AB, Akhbari M, Lavrador J, Maratos EC Abstract BACKGROUND: Cauda Equina Syndrome (CES) is a neurosurgical emergency warranting urgent surgical decompression. Treatment delay may precipitate permanent adverse neurological sequelae. CES is a clinical diagnosis, corroborated by radiological findings. Atypical presentations...
Wed Nov 13, 2019 20:07
Scoliosis correction with one ventricle: A multispecialty approach. World Neurosurg. 2019 Nov 09;: Authors: Bustillo MA, Hussain I, Virk MS, Fu KM, Scharoun JH Abstract BACKGROUND: Patients with single ventricle congenital heart disease may present for scoliosis correction. These patients undergo a series of cardiac operations which create a novel circulation that has significant impact on the management of their spinal surgery. CASE DESCRIPTION:...
Wed Nov 13, 2019 20:07
Application of the Preventable Shunt Revision Rate to an Adult Population. World Neurosurg. 2019 Nov 09;: Authors: Venable GT, Dave P, Gordon WE, Fraser BD, Wallace DA, Mangham W, Taylor DR, Khan NR, Michael LM, Vaughn BN, Klimo P Abstract INTRODUCTION: The Preventable Shunt Revision Rate (PSRR) was recently introduced in pediatric hydrocephalus as a quality metric for shunt surgery. We sought to implement the PSRR in an adult hydrocephalus population....
Wed Nov 13, 2019 20:07
Intra-reservoir administration of alteplase to treat a distal ventriculo-atrial shunt obstruction. World Neurosurg. 2019 Nov 09;: Authors: Delavari N, Mureb MC, Yaun A, Wisoff JH, Harter DH, Hidalgo ET Abstract BACKGROUND: Ventriculoatrial shunts can be afflicted with distal malfunctions due to thrombus formation at the distal tip. Distal tip thrombus formation may occur more commonly in oncologic patients who are predisposed to hypercoagulability. ...
Wed Nov 13, 2019 20:07
Risk factor analysis of the incidence of subsequent adjacent vertebral fracture following lumbar spinal fusion surgery with instrumentation. World Neurosurg. 2019 Nov 09;: Authors: Luo PJ, Tang YC, Zhou TP, Guo HZ, Guo DQ, Mo GY, Ma YH, Liu PJ, Zhang SC, Liang Abstract OBJECTIVE: This study aimed to evaluate the risk factors for adjacent vertebral compression fractures following lumbar spinal fusion with instrumentation. METHODS: A total of...
Wed Nov 13, 2019 20:07
A Perspective Statement on the Life Given by Mrs. Cantlie - The Legacy of an Iconic Graphical Representation of Neuroscientific Knowledge. World Neurosurg. 2019 Nov 09;: Authors: Surbeck W, Joswig H, Hildebrandt G PMID: 31715414 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 20:07
Does radiotherapy with surgery improve survival and decrease progression to multiple myeloma in patients with solitary plasmacytoma of bone of the spine? World Neurosurg. 2019 Nov 09;: Authors: Xie L, Wang H, Jiang J Abstract OBJECTIVE: To investigate the outcomes of radiotherapy with or without surgery during treatment of patients with solitary plasmacytoma of bone (SBP) of the spine. METHODS: Patients diagnosed with SBP of the spine who are...
Wed Nov 13, 2019 20:07
Endovascular intervention for early postoperative stenosis of extra-cranial-intra-cranial (EC-IC) bypass graft - Case report and review of the literature. World Neurosurg. 2019 Nov 09;: Authors: Chu YLE, Tsang AC, Tsang FC, Lee R, Lui WM PMID: 31715412 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 20:07
Clinical Experience of Endoscopic Endonasal Approach in the Innovative Newly Developed Operating Room "Smart Cyber Operating Theater (SCOT)": A Technical Case Report. World Neurosurg. 2019 Nov 09;: Authors: Nakamura T, Ogiwara T, Goto T, Fujii Y, Miyaoka Y, Hanaoka Y, Horiuchi T, Hongo K Abstract BACKGROUND: When the medical devices and equipment in an operating room are connected to a network, vast amounts of data concerning the progress of the operation...
Wed Nov 13, 2019 20:07
Early decompression (< 8 hours) improves the functional bladder outcome and mobility after traumatic thoracic spinal cord injury. World Neurosurg. 2019 Nov 09;: Authors: Wutte C, Becker J, Klein B, Mach O, Panzer S, Stuby FM, Strowitzki M, Maier D, Thomé C, Grassner L Abstract OBJECT: There is accumulating evidence of a potential beneficial effect of early surgical intervention after acute cervical spinal cord injury (SCI). However, around one third...
Wed Nov 13, 2019 20:07
Correlation between dural sac size in dynamic MRI and clinical symptoms in patients with lumbar spinal stenosis. World Neurosurg. 2019 Nov 09;: Authors: Zhou Z, Jin Z, Zhang P, Shan B, Zhou Z, Zhang Y, Deng Y, Zhou X Abstract OBJECTIVE: To assess the dynamic change of the dural sac size in patients with lumbar spinal stenosis (LSS) from supine to standing position and their correlations with clinical symptoms. METHODS: A final of 110 patients...
Wed Nov 13, 2019 20:07
Transformation of grade II to grade III rhabdoid-papillary meningioma: Is SRS the culprit? A case report and literature review. World Neurosurg. 2019 Nov 09;: Authors: Christodoulides I, Lavrador JP, Bodi I, Laxton R, Gullan R, Bhangoo R, Vergani F, Ashkan K Abstract In the management of meningiomas, single-fraction stereotactic radiosurgery (SRS) is an established alternative treatment to surgical resection (1). However, its effects on tumorigenesis...
Wed Nov 13, 2019 20:07
Effects of Erythrosine (E127) on Neural Tube Development in Early Chicken Embryos. World Neurosurg. 2019 Nov 09;: Authors: Ozdemir Ovalioglu A, Ovalioglu TC, Arslan S, Canaz G, Esen Aydin A, Sar M, Emel E Abstract OBJECTIVE: Erythrosine (E127), a synthetic food dye containing iodine and sodium, has been commonly used inside the packaged foods and beverages both in Turkey and in many countries. We aimed to evaluate the effects of Erythrosine on neural...
Wed Nov 13, 2019 20:07
Dural Arteriovenous Fistula of the Vein of Trolard Mimicking a Cavernous Sinus Fistula. World Neurosurg. 2019 Nov 09;: Authors: Dahl RH, Eskesen V, Benndorf G Abstract BACKGROUND: Arteriovenous fistulas (AVFs) involving the cavernous sinus usually become clinically apparent due to eye symptoms. Although rare, the same symptoms can be associated with AVFs located remote from the cavernous sinus when the shunt drains into its tributaries. We report the...
Wed Nov 13, 2019 20:07
Adjacent Level Tuberculous Spondylodiscitis Leading To Proximal Junctional Kyphosis: Rare And Unusual Presentation. World Neurosurg. 2019 Nov 09;: Authors: Mallepally AR, Tandon V, Chhabra HS Abstract INTRODUCTION: Vertebral osteomyelitis presenting as a compression fracture misdiagnosed in the setting of steroid-induced or senile osteoporosis is very rare, though they are prone to infection or reactivation as their immune system is exhausted. Spondylodiscitis...
Wed Nov 13, 2019 20:07
Brainstem Anatomy: A study on the basis of pattern of Fiber organization. World Neurosurg. 2019 Nov 09;: Authors: Shah A, Jhawar SS, Nunez M, Foundation AG, Goel A Abstract OBJECTIVE: A focused dissection of the brainstem was performed to study the various fiber bundles and gray matter nuclei of the brainstem and to decipher the intricate anatomy. METHODS: Ten formalin-fixed cadaveric human brains were procured.The fiber dissection techniques...
Wed Nov 13, 2019 20:07
AVMs: Congenital or Acquired Lesions? World Neurosurg. 2019 Nov 09;: Authors: Tasiou A, Tzerefos C, Alleyne CH, Boccardi E, Karlsson B, Kitchen N, Spetzler RF, Tolias CM, Fountas KN Abstract OBJECTIVE: Arteriovenous malformations (AVMs) have been thought to be congenital in nature. An increasing number of de novo AVM cases, however, has questioned this doctrine. METHODS: A consensus meeting of international experts, attempted to establish a...
Wed Nov 13, 2019 20:07
Planification of endocranial supra-tentorial basal cistern and skull base approaches depending on venous patterns using a topogram: Technical note. World Neurosurg. 2019 Nov 09;: Authors: Sindou M, Dumot C Abstract BACKGROUND: Because damages or sacrifices of venous drainages during supratentorial basal cistern and skull base approaches may have severe and harmful consequences, all methods to identify pre-operatively "veins at risk" are of paramount...
Wed Nov 13, 2019 20:07
Ophthalmic Arteries Arising from the Bilateral Anterior Cerebral Arteries Diagnosed by 3D TOF MR Angiography: A Case Report. World Neurosurg. 2019 Nov 09;: Authors: Ogul H PMID: 31715401 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 20:07
Related ArticlesApplication of 3D-printed craniocerebral model in simulated surgery for complex intracranial lesions. World Neurosurg. 2019 Nov 08;: Authors: Lan Q, Zhu Q, Xu L, Xu T Abstract OBJECTIVE: To demonstrate the use of 3D-printed intracranial lesion models for complex neurosurgery to increase the success rate of clinical surgeries via practice in simulated surgeries. METHODS: We collected CT, MRI, and CTA images from patients with...
Wed Nov 13, 2019 20:07
Related ArticlesIgG4 related disease of the craniovertebral junction. World Neurosurg. 2019 Nov 08;: Authors: Park BJ, Starks R, Kirby P, Menezes AH, Dlouhy BJ Abstract BACKGROUND: The majority of the abnormalities and diseases that affect the craniovertebral junction (CVJ) have already been reported, and therefore it is exceedingly rare to identify new pathology that affects the CVJ. IgG4 related disease (IgG4-RD) is an immune mediated process treated...
Wed Nov 13, 2019 20:07
Related ArticlesThe Story of the Development and Adoption of the Glasgow Coma Scale: Part I, The Early years. World Neurosurg. 2019 Nov 08;: Authors: Mattei TA, Teasdale GM Abstract The Glasgow Coma Scale and its derived Score have been adopted throughout the world for assessing the degree of impaired responsiveness in traumatic brain injury and other kinds of acute brain damage. In this historical vignette, we describe how the foundations for their...
Wed Nov 13, 2019 20:07
Related ArticlesRisk factors for urinary tract infection or pneumonia after admission for traumatic subdural hematoma at a level I trauma center: large single-institution series. World Neurosurg. 2019 Nov 08;: Authors: Pham TB, Srinivas S, Martin JR, Brandel MG, Wali AR, Rennert RC, Steinberg JA, Santiago-Dieppa DR, Costantini TW, Khalessi AA Abstract BACKGROUND: Development of infections such as urinary tract infections (UTIs) or pneumonia after a traumatic...
Wed Nov 13, 2019 20:07
Related ArticlesCarotid-cavernous fistula after transsphenoidal surgery: A rare but challenging complication. World Neurosurg. 2019 Nov 08;: Authors: Cossu G, Al-Taha K, Hajdu SD, Daniel RT, Messerer M Abstract BACKGROUND: Carotid-cavernous fistula (CCF) is a rare complication after trans-sphenoidal surgery. METHODS: The aim of this article is to report a case of CCF after the endoscopic resection of a growth hormone (GH) secreting pituitary...
Wed Nov 13, 2019 20:07
Related ArticlesCerebellar Arteriovenous Malformation with Coexistent Hemangioblastoma. World Neurosurg. 2019 Nov 08;: Authors: Monserrate Marrero JA, Monserrate Marrero AE, Pérez Berenguer JL, Álvarez EL, Corona JM, Feliciano C Abstract BACKGROUND: A case of a 40-year-old male with past medical history of smoking, hypertension, polycythemia vera, intellectual disability and schizophrenia who presented with generalized headaches, progressive loss of...
Wed Nov 13, 2019 20:07
Related ArticlesVariant Type of Posterior Reversible Encephalopathy Syndrome Associated with Deep Brain Hemorrhage: A Case Report and Literature Review. World Neurosurg. 2019 Nov 08;: Authors: Yamagami K, Maeda Y, Iihara K Abstract BACKGROUND: Various radiological patterns of posterior reversible encephalopathy syndrome (PRES) have been reported. Among them, PRES involving brainstem, thalamus, or deep white matter and lacking parieto-occipital edema...
Wed Nov 13, 2019 20:07
Silencing of Proteasome 26S Subunit ATPase 2 Regulates Colorectal Cancer Cell Proliferation, Apoptosis, and Migration. Chemotherapy. 2019 Nov 12;64(3):1-9 Authors: He J, Xing J, Yang X, Zhang C, Zhang Y, Wang H, Xu X, Wang H, Cao Y, Xu H, Zhang C, Wang C, Yu E Abstract OBJECTIVE: Colorectal cancer (CRC) remains a major cause of cancer-related death worldwide. Proteasome 26S subunit ATPase 2 (PSMC2) plays vital roles in regulating cell cycle and transcription...
Wed Nov 13, 2019 19:25
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17 Authors: Bai L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachern D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, Sun D, Stuckey JA, Wang S Abstract Signal transducer and activator of transcription 3 (STAT3) is an attractive cancer therapeutic target. Here we report the discovery of...
Wed Nov 13, 2019 19:25
NeuroD1 promotes colorectal cancer cell proliferation and tumorigenesis by suppressing p53/p21 axis.
NeuroD1 promotes colorectal cancer cell proliferation and tumorigenesis by suppressing p53/p21 axis. Cancer Sci. 2019 Nov 12;: Authors: Lei K, Li W, Huang C, Li Y, Alfason L, Zhao H, Miyagishi M, Wu S, Kasim V Abstract Neurogenic differentiation factor 1 (NeuroD1) is a transcription factor critical for promoting neuronal differentiation and maturation. NeuroD1 is involved in neuroblastoma and medulloblastoma, however, its molecular mechanism in promoting...
Wed Nov 13, 2019 19:25
Silencing Ubiquitin-conjugating Enzyme 2C Inhibits Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma. FEBS J. 2019 Nov 12;: Authors: Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H Abstract Ubiquitin-conjugating enzyme 2C (UBE2C) is a core ubiquitin-conjugating enzyme in the ubiquitin-proteasome system that promotes cell cycle progression. Previous studies have indicated that UBE2C mediates tumorigenesis...
Wed Nov 13, 2019 19:25
X-Ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors. ACS Chem Biol. 2019 Nov 12;: Authors: Arnst KE, Banerjee S, Wang Y, Chen H, Li Y, Yang L, Li W, Miller DD, Li W Abstract Because of its multifaceted role in cellular functions, tubulin is a validated and productive drug target for cancer therapy. While many tubulin inhibitors demonstrate clinical efficacy, they are often...
Wed Nov 13, 2019 19:25
Deletion of the FHL2 gene attenuates intima-media thickening in a partially ligated carotid artery ligated mouse model. J Cell Mol Med. 2019 Nov 12;: Authors: Chen CY, Tsai HY, Tsai SH, Chu PH, Huang PH, Chen JW, Lin SJ Abstract The four and a half LIM domain protein 2 (FHL2) is a member of the four and a half LIM domain (FHL) gene family, and it is associated with cholesterol-enriched diet-promoted atherosclerosis. However, the effect of FHL2 protein...
Wed Nov 13, 2019 19:25
DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging. Elife. 2019 11 12;8: Authors: Crane MM, Russell AE, Schafer BJ, Blue BW, Whalen R, Almazan J, Hong MG, Nguyen B, Goings JE, Chen KL, Kelly R, Kaeberlein M Abstract Genome instability is a hallmark of aging and contributes to age-related disorders such as cancer and Alzheimer's disease. The accumulation of DNA damage during aging has been linked...
Wed Nov 13, 2019 19:25
MiR-1/GOLPH3/Foxo1 Signaling Pathway Regulates Proliferation of Bladder Cancer. Technol Cancer Res Treat. 2019 Jan-Dec;18:1533033819886897 Authors: Liu MK, Ma T, Yu Y, Suo Y, Li K, Song SC, Zhang W Abstract OBJECTIVE: To investigate role of microRNA-1/Golgi phosphoprotein 3/Foxo1 axis in bladder cancer. METHODS: The expression of Golgi phosphoprotein 3 was determined in both bladder cancer tissues and cell lines using quantitative real-time...
Wed Nov 13, 2019 19:25
Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Cancer Med. 2019 Nov 12;: Authors: Stefka AT, Johnson D, Rosebeck S, Park JH, Nakamura Y, Jakubowiak AJ Abstract Multiple myeloma (MM) continues to be considered incurable, necessitating new drug discovery. The mitotic kinase T-LAK cell-originated protein kinase/PDZ-binding kinase (TOPK/PBK) is associated with proliferation of tumor cells, maintenance of cancer stem cells,...
Wed Nov 13, 2019 19:25
Acidic pH derived from cancer cells as a double-edged knife modulates wound healing through DNA repair genes and autophagy. Int Wound J. 2019 Nov 11;: Authors: Rabiee Motmaen S, Tavakol S, Joghataei MT, Barati M Abstract Wound healing is a sequester program that involves diverse cell signalling cascades. Notwithstanding, complete signal transduction pathways underpinning acidic milieu derived from cancer cells is not clear, yet. MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium...
Wed Nov 13, 2019 19:25
Related ArticlesAntiproliferative activity and apoptosis induction, of organo-antimony(III)-copper(I) conjugates, against human breast cancer cells. Mol Divers. 2019 Nov 11;: Authors: Banti CN, Tsiatouras V, Karanicolas K, Panagiotou N, Tasiopoulos AJ, Kourkoumelis N, Hadjikakou SK Abstract Three known organo-antimony(III)-copper(I), mixed-metal small bioactive molecules (SBAMs) of formula [Cu(tpSb)3Cl] (1), [Cu2(tpSb)4Br2] (2) and [Cu2(tpSb)4I2] (3)...
Wed Nov 13, 2019 19:25
Related ArticlesExosomes derived from cancer stem cells of gemcitabine-resistant pancreatic cancer cells enhance drug resistance by delivering miR-210. Cell Oncol (Dordr). 2019 Nov 12;: Authors: Yang Z, Zhao N, Cui J, Wu H, Xiong J, Peng T Abstract PURPOSE: Gemcitabine (GEM)-based chemotherapy is the first-line treatment for locally advanced pancreatic cancer. GEM resistance, however, remains a significant clinical challenge. Here, we investigated whether...
Wed Nov 13, 2019 19:25
Related ArticlesSuppression of BCL6 function by HDAC inhibitor mediated acetylation and chromatin modification enhances BET inhibitor effects in B-cell lymphoma cells. Sci Rep. 2019 Nov 11;9(1):16495 Authors: Cortiguera MG, García-Gaipo L, Wagner SD, León J, Batlle-López A, Delgado MD Abstract Multiple genetic aberrations in the regulation of BCL6, including in acetyltransferase genes, occur in clinically aggressive B-cell lymphomas and lead to higher...
Wed Nov 13, 2019 19:25
Related ArticlesPrediction of Deleterious Non-synonymous SNPs of Human STK11 Gene by Combining Algorithms, Molecular Docking, and Molecular Dynamics Simulation. Sci Rep. 2019 Nov 11;9(1):16426 Authors: Islam MJ, Khan AM, Parves MR, Hossain MN, Halim MA Abstract Serine-threonine kinase11 (STK11) is a tumor suppressor gene which plays a key role in regulating cell growth and apoptosis. It is widely known as a multitasking kinase and engaged in cell polarity,...
Wed Nov 13, 2019 19:25
Related ArticlesA feedback loop of conditionally stable circuits drives the cell cycle from checkpoint to checkpoint. Sci Rep. 2019 Nov 11;9(1):16430 Authors: Deritei D, Rozum J, Ravasz Regan E, Albert R Abstract We perform logic-based network analysis on a model of the mammalian cell cycle. This model is composed of a Restriction Switch driving cell cycle commitment and a Phase Switch driving mitotic entry and exit. By generalizing the concept of stable...
Wed Nov 13, 2019 19:25
Related ArticlesLong non-coding RNA H19 promotes tumorigenesis of multiple myeloma by activating BRD4 signaling by targeting miR-152-3p. Mol Cell Biol. 2019 Nov 11;: Authors: Zheng JF, Guo NH, Zi FM, Cheng J Abstract Multiple myeloma (MM) accounts for over twenty percent of hematological cancer-related death worldwide. Long non-coding RNA (lncRNA) H19 is associated with multiple tumorigenesis and is increased in MM, but the underlying mechanism of H19...
Wed Nov 13, 2019 19:25
Related ArticlesA fluorinated phenylbenzothiazole arrest the Trypanosoma cruzi cell cycle and diminishes the mammalian host-cell infection. Antimicrob Agents Chemother. 2019 Nov 11;: Authors: Cuevas-Hernández RI, Girard RMBM, Martínez-Cerón S, Santos da Silva M, Elias MC, Crispim M, Trujillo-Ferrara JG, Silber AM Abstract Chagas disease (CD) is a human infection caused by Trypanosoma cruzi CD was traditionally endemic to the Americas, however, due to...
Wed Nov 13, 2019 19:25
Related ArticlesFAM122A supports the growth of hepatocellular carcinoma cells and its deletion enhances Doxorubicin-induced cytotoxicity. Exp Cell Res. 2019 Nov 08;:111714 Authors: Zhou Y, Shi WY, He W, Yan ZW, Liu MH, Chen J, Yang YS, Wang YQ, Chen GQ, Huang Y Abstract FAM122A protein is a highly conserved in mammals, however its function is still largely unknown so far. In this study, we investigated the potential role of FAM122A in hepatocellular...
Wed Nov 13, 2019 19:25
Related ArticlesRegulation of programmed death-ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine. Cancer Sci. 2019 Nov;110(11):3415-3423 Authors: Sato H, Jeggo PA, Shibata A Abstract Anti-programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) therapy, which is one of the most promising cancer therapies, is licensed for treating various tumors. Programmed death-ligand 1, which is expressed on the...
Wed Nov 13, 2019 19:25
Related ArticlesRapamycin, proliferation and geroconversion to senescence. Cell Cycle. 2018;17(24):2655-2665 Authors: Blagosklonny MV Abstract Rapamycin inhibits cell proliferation, yet preserves (re)-proliferative potential (RPP). RPP is a potential of quiescent cells that is lost in senescent cells. mTOR drives conversion from quiescence to senescence (geroconversion). By suppressing geroconversion, rapamycin preserves RPP. Geroconversion is characterized...
Wed Nov 13, 2019 19:25
Related ArticlesCombination Immune Checkpoint Blockade Strategies to Maximize Immune Response in Gynecological Cancers. Curr Oncol Rep. 2018 11 13;20(12):94 Authors: Liu YL, Zamarin D Abstract PURPOSE OF REVIEW: Immune checkpoint blockade targeting PD-1 and PD-L1 improves immune recognition of tumor cells but had only modest success in gynecological cancers as monotherapy. Growing focus has been placed on combination immunotherapy strategies to overcome...
Wed Nov 13, 2019 19:25
Related ArticlesMiR-448 downregulates CTTN to inhibit cell proliferation and promote apoptosis in glioma. Eur Rev Med Pharmacol Sci. 2018 06;22(12):3847-3854 Authors: Su HY, Lin ZY, Peng WC, Guan F, Zhu GT, Mao BB, Dai B, Huang H, Hu ZQ Abstract OBJECTIVE: miRNAs have been confirmed to be related to cell proliferation and apoptosis. In this study, we detected the potential effect of miR-448 on glioma cell proliferation and apoptosis. MATERIALS...
Wed Nov 13, 2019 19:25
Related ArticlesNegative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer. Ann Oncol. 2018 06 01;29(6):1437-1444 Authors: Derosa L, Hellmann MD, Spaziano M, Halpenny D, Fidelle M, Rizvi H, Long N, Plodkowski AJ, Arbour KC, Chaft JE, Rouche JA, Zitvogel L, Zalcman G, Albiges L, Escudier B, Routy B Abstract Background: The composition of gut microbiota...
Wed Nov 13, 2019 19:25
Related ArticlesDistinct effects of epirubicin, cisplatin and cyclophosphamide on ovarian somatic cells of prepuberal ovaries. Aging (Albany NY). 2019 Nov 11;11: Authors: Marcozzi S, Rossi V, Salvatore G, Rella FD, De Felici M, Klinger FG Abstract In vitro culture models were used to characterize the effects of chemotherapeutic drugs and of LH on somatic cells from prepuberal mouse ovaries. All cell types (pre- and granulosa cells, pre-thecal and OSE...
Tue Nov 12, 2019 16:28
Related ArticlesChlorinated effluent organic matter causes higher toxicity than chlorinated natural organic matter by inducing more intracellular reactive oxygen species. Sci Total Environ. 2019 Nov 01;701:134881 Authors: Du Y, Wang WL, He T, Sun YX, Lv XT, Wu QY, Hu HY Abstract During unplanned indirect potable reuse, treated wastewater that contains effluent organic matter (EOM) enters the drinking water source, resulting in different toxicity from...
Tue Nov 12, 2019 16:28
Related ArticlesButylated hydroxyanisole induces testicular dysfunction in mouse testis cells by dysregulating calcium homeostasis and stimulating endoplasmic reticulum stress. Sci Total Environ. 2019 Nov 02;702:134775 Authors: Ham J, Lim W, You S, Song G Abstract Butylated hydroxyanisole (BHA), a synthetic phenolic antioxidant (SPA), has been used as a food additive. However, BHA acts as an environmental hormone, i.e., endocrine disruptor. Here, we...
Tue Nov 12, 2019 16:28
Related ArticlesPatterns of protein expression in human head and neck cancer cell lines differ after proton vs photon radiotherapy. Head Neck. 2019 Nov 11;: Authors: Wang L, Yang L, Han S, Zhu J, Li Y, Wang Z, Fan YH, Lin E, Zhang R, Sahoo N, Li Y, Zhang X, Wang X, Li T, Zhu XR, Zhu H, Heymach JV, Myers JN, Frank SJ Abstract BACKGROUND: Proton radiotherapy (PRT) may be a less toxic alternative to photon radiotherapy (XRT) for patients with head and neck...
Tue Nov 12, 2019 16:28
Related ArticlesATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop. Mol Cell. 2019 Oct 28;: Authors: Matos DA, Zhang JM, Ouyang J, Nguyen HD, Genois MM, Zou L Abstract R loops arising during transcription induce genomic instability, but how cells respond to the R loop-associated genomic stress is still poorly understood. Here, we show that cells harboring high levels of R loops rely on the ATR kinase for survival. In response...
Tue Nov 12, 2019 13:35
Related ArticlesEthyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities. Bioorg Chem. 2019 Oct 24;:103371 Authors: Attalah KM, Abdalla AN, Aslam A, Ahmed M, Abourehab MAS, ElSawy NA, Gouda AM Abstract Two new series of ethyl benzoate bearing pyrrolizine and indolizine moieties 8-11 were synthesized and evaluated for their anti-inflammatory and anticancer activities....
Tue Nov 12, 2019 13:35
Related ArticlesLukS-PV induces cell cycle arrest and apoptosis through p38/ERK MAPK signaling pathway in NSCLC cells. Biochem Biophys Res Commun. 2019 Nov 07;: Authors: Qiang Y, Ma F, Wang Z, Nie Z, Xu L, Ding P, Ma X Abstract Non-small-cell lung cancer (NSCLC) accounts for nearly 85% of lung cancer cases. LukS-PV, one of the two components of Panton-Valentine leucocidin (PVL), is produced by Staphylococcus aureus. The present study showed that LukS-PV...
Tue Nov 12, 2019 13:35
Related ArticlesBET inhibitor bromosporine enhances 5-FU effect in colorectal cancer cells. Biochem Biophys Res Commun. 2019 Nov 07;: Authors: Cheng X, Huang Z, Long D, Jin W Abstract Treatment of colorectal cancer (CRC) remains a challenge because of the lack of effective early treatment strategies and high incidence of relapse. 5-Fluorouracil (5-FU) is a typical CRC treatment. Bromosporine is an innovative bromodomain and extraterminal domain (BET)...
Tue Nov 12, 2019 13:35
Related Articles[CEP55 may be a potential therapeutic target for non-obstructive azoospermia with maturation arrest]. Nan Fang Yi Ke Da Xue Xue Bao. 2019 Sep 30;39(9):1059-1064 Authors: Zhu Y, Liu J, Zhang W, Wu J, Li W, Li H, Chu Q, Luo C Abstract OBJECTIVE: To explore the effect of small interfering RNA (siRNA)-mediated CEP55 gene silencing on the proliferation of mouse spermatogonia. METHODS: Six patients with azoospermia diagnosed to have...
Tue Nov 12, 2019 13:35
Effects on executive functions of antiepileptic monotherapy in pediatric age. Epilepsy Behav. 2019 Nov 09;102:106648 Authors: Operto FF, Pastorino GMG, Mazza R, Carotenuto M, Roccella M, Marotta R, di Bonaventura C, Verrotti A Abstract OBJECTIVES: Cognitive abilities and executive functions in children and adolescents are important indicators of quality of life as well as academic and social achievements. Cognitive and executive functioning are often...
Wed Nov 13, 2019 19:53
Distinct functional alterations in SCN8A epilepsy mutant channels. J Physiol. 2019 Nov 12;: Authors: Pan Y, Cummins TR Abstract KEY POINTS: •Mutations in the SCN8A gene cause early infantile epileptic encephalopathy. •We characterize a new epilepsy-related SCN8A mutation, R850Q, in the human SCN8A channel and present gain-of-function properties of the mutant channel. •Systematic comparison of R850Q with three other SCN8A epilepsy mutations, T761I, R1617Q,...
Wed Nov 13, 2019 19:53
Therapeutic drug monitoring newer antiepileptic drugs: a randomised trial for dosage adjustment. Ann Neurol. 2019 Nov 12;: Authors: Aícua-Rapún I, André P, Rossetti AO, Ryvlin P, Hottinger AF, Decosterd LA, Buclin T, Novy J Abstract OBJECTIVE: Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is widely established for older generation AEDs, whereas there is limited evidence about newer AEDs. Our aim is to assess the benefit of newer generation...
Wed Nov 13, 2019 19:53
Related ArticlesTreatment of refractory and superrefractory status epilepticus with topiramate: A cohort study of 106 patients and a review of the literature. Epilepsia. 2019 Nov 11;: Authors: Fechner A, Hubert K, Jahnke K, Knake S, Konczalla J, Menzler K, Ronellenfitsch MW, Rosenow F, Strzelczyk A Abstract OBJECTIVE: Novel treatments are needed to control treatment-resistant status epilepticus (SE). We present a summary of clinical cases where oral...
Wed Nov 13, 2019 19:53
Related ArticlesBlood-brain barrier dysfunction in status epileptics: Mechanisms and role in epileptogenesis. Epilepsy Behav. 2019 Nov 08;:106285 Authors: Swissa E, Serlin Y, Vazana U, Prager O, Friedman A Abstract The blood-brain barrier (BBB), a unique anatomical and physiological interface between the central nervous system (CNS) and the peripheral circulation, is essential for the function of neural circuits. Interactions between the BBB, cerebral...
Wed Nov 13, 2019 19:53
Related ArticlesUsing artwork to understand and address the psychosocial challenges facing children and adolescents with epilepsy. Epilepsy Behav. 2019 Nov 08;:106572 Authors: Stafstrom CE Abstract Artwork is a valuable and underutilized technique for exploring the self-esteem and psychological challenges facing children and adolescents with epilepsy and other chronic diseases. Having children with epilepsy draw a picture of their seizure correlates...
Wed Nov 13, 2019 19:53
Related ArticlesHippocampal Contributions to Model-Based Planning and Spatial Memory. Neuron. 2019 05 08;102(3):683-693.e4 Authors: Vikbladh OM, Meager MR, King J, Blackmon K, Devinsky O, Shohamy D, Burgess N, Daw ND Abstract Little is known about the neural mechanisms that allow humans and animals to plan actions using knowledge of task contingencies. Emerging theories hypothesize that it involves the same hippocampal mechanisms that support self-localization...
Wed Nov 13, 2019 19:53
Related ArticlesLamotrigine-associated hemophagocytic lymphohistiocytosis. Blood. 2019 03 07;133(10):1165 Authors: Hancock CL, Gálvez A PMID: 30846511 [PubMed - indexed for MEDLINE]
Wed Nov 13, 2019 19:53
AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro.
Related ArticlesAMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro. PLoS One. 2019;14(2):e0211644 Authors: Lange F, Weßlau K, Porath K, Hörnschemeyer J, Bergner C, Krause BJ, Mullins CS, Linnebacher M, Köhling R, Kirschstein T Abstract Epileptic seizures are frequent in patients with glioblastoma, and anticonvulsive treatment is often necessary. While clinical guidelines recommend all approved anticonvulsants,...
Wed Nov 13, 2019 19:53
Related ArticlesDetermination of Content Validity of the Epilepsy Monitoring Unit Comfort Questionnaire Using the Content Validity Index. J Nurs Meas. 2018 08;26(2):398-410 Authors: Egger-Rainer A Abstract BACKGROUND AND PURPOSE: The Epilepsy Monitoring Unit Comfort Questionnaire (EMUCQ) is a self-assessment instrument to measure perceived patient comfort during hospitalization in an EMU. This study aimed at initially determining the content validity...
Wed Nov 13, 2019 19:53
Related ArticlesAging is associated with a mild acidification in neocortical human neurons in vitro. J Neural Transm (Vienna). 2018 10;125(10):1495-1501 Authors: Bonnet U, Bingmann D, Speckmann EJ, Wiemann M Abstract The intracellular pH (pHi) in the cytosol of mammalian central neurons is tightly regulated and small pHi-fluctuations are deemed to modulate inter-/intracellular signaling, excitability, and synaptic plasticity. The resting pHi of young...
Wed Nov 13, 2019 19:53
Related ArticlesSafety of slow-pulsed transcranial electrical stimulation in acute spike suppression. Ann Clin Transl Neurol. 2019 Nov 11;: Authors: Holmes MD, Feng R, Wise MV, Ma C, Ramon C, Wu J, Luu P, Hou J, Pan L, Tucker DM Abstract We examined the effects of slow-pulsed transcranial electrical stimulation (TES) in suppressing epileptiform discharges in seven adults with refractory epilepsy. An MRI-based realistic head model was constructed for...
Tue Nov 12, 2019 14:16
Related ArticlesSeizure freedom improves health-related quality of life after epilepsy surgery in children. Dev Med Child Neurol. 2019 Nov 11;: Authors: Jain P, Smith ML, Speechley K, Ferro M, Connolly M, Ramachandrannair R, Almubarak S, Andrade A, Widjaja E, Pepsqol Study Team Abstract AIM: To determine whether epilepsy surgery improved health-related quality of life (HRQoL) and whether seizure freedom after surgery mediated the improvement in HRQoL....
Tue Nov 12, 2019 14:16
Related ArticlesTreatment Patterns and Use of Resources in Patients With Tuberous Sclerosis Complex: Insights From the TOSCA Registry. Front Neurol. 2019;10:1144 Authors: Marques R, Belousova E, Benedik MP, Carter T, Cottin V, Curatolo P, Dahlin M, D'Amato L, Beaure d'Augères G, de Vries PJ, Ferreira JC, Feucht M, Fladrowski C, Hertzberg C, Jozwiak S, Lawson JA, Macaya A, Nabbout R, O'Callaghan F, Qin J, Sander V, Sauter M, Shah S, Takahashi Y, Touraine R, Youroukos S,...
Tue Nov 12, 2019 14:16
Related ArticlesEvolution of concepts in epilepsy surgery. Epileptic Disord. 2019 Oct 01;21(5):391-409 Authors: Engel J Abstract At the time of the first meeting of the International League Against Epilepsy (ILAE) in 1909, surgical treatment for epilepsy had been accepted as an alternative therapy for over two decades, but was rarely practiced, considered a last resort for carefully selected patients. Localization was based on ictal semiology and identification...
Tue Nov 12, 2019 14:16
Related ArticlesNovel treatment approaches and pediatric research networks in status epilepticus. Epilepsy Behav. 2019 Nov 07;:106564 Authors: Bialer M, Cross H, Hedrich UBS, Lagae L, Lerche H, Loddenkemper T Abstract This paper contains five contributions which were presented as part of the novel therapies section of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures. These illustrate recent advances being made in the management...
Tue Nov 12, 2019 14:16
Related ArticlesWhy do patients die after status epilepticus? Epilepsy Behav. 2019 Nov 08;:106567 Authors: Hocker S Abstract The epidemiology of status epilepticus (SE) and predictors of outcome in particular have been well described with consistent findings around the world. Understanding of the actual causes of death in patients hospitalized with SE is limited. The following is a summary of published information about causes of death in patients hospitalized...
Tue Nov 12, 2019 14:16
Related ArticlesRisks and management of antiepileptic drug induced skin reactions in the adult out-patient setting. Seizure. 2019 Jul 03;: Authors: Fowler T, Bansal AS, Lozsádi D Abstract Adverse cutaneous reactions caused by mostly aromatic antiepileptic drugs (AED) affect 50.000 people a year in the United Kingdom (UK; incidence 75.7/100.000). Optimal management of these cases is often difficult, as the patient may report symptoms to a general practitioner,...
Tue Nov 12, 2019 14:16
Related Articles[New anti-epileptic drugs in Paediatrics]. An Pediatr (Barc). 2019 Nov 07;: Authors: Málaga I, Sánchez-Carpintero R, Roldán S, Ramos-Lizana J, García-Peñas JJ Abstract It is estimated that about 70 million people all over the world suffer from epilepsy, half of which are children, in whom the prevalence is around 0.5 to 0.8%. Although there are several therapies, the treatment of epilepsy is based mainly on drugs, which, depending on...
Tue Nov 12, 2019 14:16
Related ArticlesThe Power and Peril of Panels. Hosp Pediatr. 2018 11;8(11):729-732 Authors: Morrison JM, Dudas RA, Collins K PMID: 30337337 [PubMed - indexed for MEDLINE]
Tue Nov 12, 2019 14:16
Related ArticlesContribution of Quantitative Amygdalar MR FLAIR Signal Analysis for Lateralization of Mesial Temporal Lobe Epilepsy. J Neuroimaging. 2018 11;28(6):666-675 Authors: Jafari-Khouzani K, Elisevich K, Wasade VS, Soltanian-Zadeh H Abstract BACKGROUND AND PURPOSE: This study evaluates the contribution of an automated amygdalar fluid-attenuated inversion recovery (FLAIR) signal analysis for the lateralization of mesial temporal lobe epilepsy...
Tue Nov 12, 2019 14:16
Related ArticlesThe effect of delayed anti-NMDAR encephalitis recognition on disease outcome. J Neurovirol. 2018 10;24(5):638-641 Authors: Sulentic V, Petelin Gadze Z, Derke F, Santini M, Bazadona D, Nankovic S Abstract Anti-NMDA receptor encephalitis is an acute form of brain inflammation that is potentially lethal but has a high probability for recovery with treatment. Although the clinical picture of anti-NMDAR encephalitis is usually recognizable...
Tue Nov 12, 2019 14:16
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