Related ArticlesProtein-assisted RNA fragment docking (RnaX) for modeling RNA-protein interactions using ModelX. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Delgado Blanco J, Radusky LG, Cianferoni D, Serrano L Abstract RNA-protein interactions are crucial for such key biological processes as regulation of transcription, splicing, translation, and gene silencing, among many others. Knowing where an RNA molecule interacts with a target protein and/or...
Sun Nov 17, 2019 17:46
Related ArticlesThe retrograde signaling protein GUN1 regulates tetrapyrrole biosynthesis. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Shimizu T, Kacprzak SM, Mochizuki N, Nagatani A, Watanabe S, Shimada T, Tanaka K, Hayashi Y, Arai M, Leister D, Okamoto H, Terry MJ, Masuda T Abstract The biogenesis of the photosynthetic apparatus in developing seedlings requires the assembly of proteins encoded on both nuclear and chloroplast genomes. To coordinate...
Sun Nov 17, 2019 17:46
Related ArticlesLearning optimal decisions with confidence. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Drugowitsch J, Mendonça AG, Mainen ZF, Pouget A Abstract Diffusion decision models (DDMs) are immensely successful models for decision making under uncertainty and time pressure. In the context of perceptual decision making, these models typically start with two input units, organized in a neuron-antineuron pair. In contrast, in the brain, sensory...
Sun Nov 17, 2019 17:46
Related ArticlesBody map proto-organization in newborn macaques. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Arcaro MJ, Schade PF, Livingstone MS Abstract Topographic sensory maps are a prominent feature of the adult primate brain. Here, we asked whether topographic representations of the body are present at birth. Using functional MRI (fMRI), we find that the newborn somatomotor system, spanning frontoparietal cortex and subcortex, comprises multiple...
Sun Nov 17, 2019 17:46
Related ArticlesThermal reaction and luminescence of long-lived N 2D in N2 ice. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Lo JI, Chou SL, Peng YC, Lu HC, Cheng BM Abstract Photochemistry of an N2 ice and thermal reaction of the irradiated sample were studied with vacuum-ultraviolet (VUV) light from a synchrotron. Concurrent detection of infrared absorption and visible emission spectra provide evidence for the generation of energetic products N...
Sun Nov 17, 2019 17:46
Related ArticlesLabel-free visualization and characterization of extracellular vesicles in breast cancer. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: You S, Barkalifa R, Chaney EJ, Tu H, Park J, Sorrells JE, Sun Y, Liu YZ, Yang L, Chen DZ, Marjanovic M, Sinha S, Boppart SA Abstract Despite extensive interest, extracellular vesicle (EV) research remains technically challenging. One of the unexplored gaps in EV research has been the inability to characterize...
Sun Nov 17, 2019 17:46
Related ArticlesCombined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: Srivastava RK, Li C, Khan J, Banerjee NS, Chow LT, Athar M Abstract The mammalian target of rapamycin (mTOR) pathway, which plays a critical role in regulating cellular growth and metabolism, is aberrantly regulated in the pathogenesis of a variety of neoplasms. Here we demonstrate...
Sun Nov 17, 2019 17:46
Related ArticlesHERES, a lncRNA that regulates canonical and noncanonical Wnt signaling pathways via interaction with EZH2. Proc Natl Acad Sci U S A. 2019 Nov 15;: Authors: You BH, Yoon JH, Kang H, Lee EK, Lee SK, Nam JW Abstract Wnt signaling through both canonical and noncanonical pathways plays a core role in development. Dysregulation of these pathways often causes cancer development and progression. Although the pathways independently contribute...
Sun Nov 17, 2019 17:46
Related ArticlesScreening of genetic variants in ELANE mutation negative congenital neutropenia by next generation sequencing. J Clin Pathol. 2019 Nov 15;: Authors: Arunachalam AK, Suresh H, Edison ES, Korula A, Aboobacker FN, George B, Shaji RV, Mathews V, Balasubramanian P Abstract AIMS: Congenital neutropenia (CN) is a rare inherited disease that results in recurrent, life-threatening bacterial infections due to a deficiency of mature neutrophils....
Sun Nov 17, 2019 17:42
Related ArticlesEvaluation of the delta of immature platelet fraction as a predictive biomarker of inflammatory response after cardiac surgery. J Clin Pathol. 2019 Nov 15;: Authors: Imperiali CE, Lopez-Delgado JC, Dastis-Arias M, Sanchez-Navarro L Abstract AIMS: Cardiac surgery (CS) can induce an inflammatory response (IR) that is associated with poorer outcomes. Immature platelets are among the factors that may be associated with IR development. We...
Sun Nov 17, 2019 17:42
Related ArticlesCritical appraisal of predatory journals in pathology. J Clin Pathol. 2019 Nov 15;: Authors: AlAhmad YM, Abdelhafez I, Cyprian FS, Akhtar S, Skenderi F, Vranic S PMID: 31732617 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 17:42
Related ArticlesAlopecia universalis treated with simvastatin/ezetimibe, minoxidil, and prednisolone in a 6-year-old girl. Int J Dermatol. 2019 Nov 15;: Authors: Ismail FF, Sinclair R PMID: 31732969 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 17:42
Related ArticlesCardiopulmonary failure as a result of brainstem encephalitis caused by enterovirus D68. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Yogo N, Imamura T, Muto Y, Hirai K Abstract Enterovirus D68 (EV-D68) causes respiratory illnesses such as pneumonia, and has been reported to cause acute flaccid myelitis. Enterovirus A71 (EV-A71) is known to cause cardiopulmonary failure due to brainstem encephalitis, but there have been few reports of these...
Sun Nov 17, 2019 17:32
Related ArticlesEpstein-Barr virus-associated acute pancreatitis. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Hammami MB, Aboushaar R, Musmar A, Hammami S Abstract Epstein-Barr virus (EBV) infection is mostly subclinical and resolves spontaneously without complications. Gastroenterology involvement usually manifests as asymptomatic liver enzymes elevation. We report a new case of acute pancreatitis complicating EBV infection and review the literature....
Sun Nov 17, 2019 17:32
Related ArticlesVocal cord surgery and pharmacological treatment of a patient with HPV and recurrent respiratory papillomatosis. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Galletti F, Freni F, Gazia F, Gallo A Abstract Recurrent respiratory papillomatosis (RRP) is caused by persistent infection of the respiratory epithelium by human papillomavirus (HPV), especially HPV 6 and 11. We present a case of surgically treated RRP. The main purpose of our protocol...
Sun Nov 17, 2019 17:32
Related ArticlesCase of non-alcoholic Wernicke's encephalopathy. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Theodoreson MD, Zykaite A, Haley M, Meena S Abstract A 61-year-old obese man presented with 8-week history of nausea and occasional vomiting. He reported poor appetite and unintentional weight loss of more than 20 kg of his body mass. A week after admission, he developed double vision and unsteady gait. Neurological examination revealed isolated...
Sun Nov 17, 2019 17:32
Related ArticlesBurkholderia cepacia complex infection complicating long-term urethral catheterisation. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Ogundipe OA, Pearson RC, Campbell A Abstract This report describes a 79-year-old Caucasian man with a history of syringomyelia, paraplegia and a long-term urethral catheter, presenting with recurrent catheter-related or catheter-associated urinary tract infections (CAUTIs) and persistent delirium. On one occasion,...
Sun Nov 17, 2019 17:32
Related ArticlesAcute kidney injury as the presenting complaint of ceftazidime-induced immune-mediated haemolysis. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Ferro A, Griffiths M, Smith R, Fry A Abstract We present the case of ceftazidime-induced immune-mediated haemolysis with associated acute kidney injury in a 43-year-old woman. The patient initially presented to the regional cystic fibrosis centre for treatment of an infective exacerbation of cystic...
Sun Nov 17, 2019 17:32
Related ArticlesThe dilemma of whether to continue TNFα blocker therapy in an ulcerative colitis patient newly diagnosed with a malignant melanoma and melanoma in situ. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Zuzarte L, Mirhadi S, Carr RA, Tso S PMID: 31732538 [PubMed - in process]
Sun Nov 17, 2019 17:32
Related ArticlesLarge spontaneous perirenal haematoma following percutaneous transluminal coronary angioplasty. BMJ Case Rep. 2019 Nov 14;12(11): Authors: Attri V, Parmar KM, Prateek T, Kumar S Abstract Perirenal haematoma is a rare and life-threatening condition in view of severe and ongoing blood loss. Most common causes are renal cancer, angiomyolipoma and vasculitis. Spontaneous causes of this rare entity may occur with use of anticoagulants and...
Sun Nov 17, 2019 17:32
Related ArticlesPectin lyase-modified red ginseng extract improves glucose homeostasis in high fat diet-fed mice. J Ethnopharmacol. 2019 Nov 13;:112384 Authors: Kim GW, Pyo MK, Chung SH Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Red ginseng has long been used as a traditional folk medicine for various diseases including diabetes. Recently, a preparation of red ginseng extract by pectin lyase modification has been developed and named as GS-E3D. ...
Sun Nov 17, 2019 17:32
Related ArticlesAqueous extract of Digitaria exilis gra4ins ameliorate diabetes in streptozotocin-induced diabetic male Wistar rats. J Ethnopharmacol. 2019 Nov 13;:112383 Authors: Adams DM, Yakubu MT Abstract ETHNOPHARMACOLOGICAL RELEVANCE: The absence of scientific data on the age long folkloric use of Digitaria exilis grains by sufferers of diabetes prompted the present investigation. This study was aimed at evaluating the antidiabetic activity of...
Sun Nov 17, 2019 17:32
Related ArticlesAmeliorative potential of Argyreia speciosa against CCI-induced neuropathic pain in rats: Biochemical and histopathological studies. J Ethnopharmacol. 2019 Nov 13;:112399 Authors: Singh H, Kaur J, Arora R, Mannan R, Buttar HS, Arora S, Singh B PMID: 31733307 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 17:32
Related ArticlesThe role of the anterior and midcingulate cortex in the neurobiology of functional neurologic disorder. Handb Clin Neurol. 2019;166:267-279 Authors: Ospina JP, Jalilianhasanpour R, Perez DL Abstract Functional neurologic disorder (FND)/conversion disorder is a prevalent and disabling condition at the intersection of neurology and psychiatry. Clinicians often report feeling ill-equipped treating patients with FND, perpetuated by a historically...
Sun Nov 17, 2019 17:27
Related ArticlesIntroduction to the NIDILRR Burn Model System (BMS) Program: Selected Findings II. Arch Phys Med Rehabil. 2019 Nov 13;: Authors: Holavanahalli RK, Schneider JC, Miller AC Abstract A special supplement to the Archives of Physical Medicine and Rehabilitation in 2007 reported selected findings of research from the first 13 years of the BMS Centers and Database Coordinating Center. This special supplement is the second such effort and reports...
Sun Nov 17, 2019 17:21
Related ArticlesStandard Setting of Competency in Mastoidectomy for the Cross-Institutional Mastoidectomy Assessment Tool. Ann Otol Rhinol Laryngol. 2019 Nov 15;:3489419889376 Authors: Kerwin T, Wiet G, Hittle B, Stredney D, De Boeck P, Moberly A, Andersen SAW Abstract OBJECTIVE: Competency-based surgical training involves progressive autonomy given to the trainee. This requires systematic and evidence-based assessment with well-defined standards of...
Sun Nov 17, 2019 17:20
Related ArticlesUtility of Audiometry in the Evaluation of Patients Presenting with Dysphonia. Ann Otol Rhinol Laryngol. 2019 Nov 15;:3489419889373 Authors: Ross J, Valentino WL, Calder A, Bigly D, Othman S, McKinnon B, Sataloff RT Abstract OBJECTIVES: Hearing loss has been implicated in dysphonia secondary to voice misuse, although the data supporting this claim are scant. Determining the prevalence of hearing loss in patients with dysphonia and correlating...
Sun Nov 17, 2019 17:20
Related ArticlesPediatric Thyroidectomy: NSQIP-P Analysis of Adverse Perioperative Outcomes. Ann Otol Rhinol Laryngol. 2019 Nov 15;:3489419889069 Authors: Patel VA, Khaku A, Carr MM Abstract BACKGROUND: This study identifies risk factors and 30-day adverse outcomes of pediatric patients undergoing thyroidectomy. METHODS: Retrospective analysis utilizing the American College of Surgeons National Surgical Quality Improvement-Pediatric Database...
Sun Nov 17, 2019 17:20
Related ArticlesVolume Change after Endovascular Treatment of Common Iliac Arteries ≥ 17 mm Diameter: Assessment of Type 1b Endoleak Risk Factors. Eur J Vasc Endovasc Surg. 2019 Nov 12;: Authors: Rouby AF, Kuntz S, Delay C, Thaveau F, Georg Y, Lejay A, Chakfe N Abstract OBJECTIVE: The aim of this study was to assess the post-operative volumetric evolution of common iliac arteries (CIA) ≥ 17 mm diameter with respect to the type of endovascular technique...
Sun Nov 17, 2019 17:19
Related ArticlesHyperglycaemia and Ischaemia Impair Wound Healing via Toll-like Receptor 4 Pathway Activation in vitro and in an Experimental Murine Model. Eur J Vasc Endovasc Surg. 2019 Nov 12;: Authors: Portou MJ, Yu R, Baker D, Xu S, Abraham D, Tsui J Abstract OBJECTIVE: Diabetes mellitus has reached epidemic proportions. Foot ulceration is a multifactorial complication of diabetes associated with marked morbidity and mortality. Innate immune Toll-like...
Sun Nov 17, 2019 17:19
Related ArticlesResponse to Letter to the Editor re 'Impact of Prosthetic Graft Replacement of the Ascending Aorta on Circumferential Strain in the Descending Aorta'. Eur J Vasc Endovasc Surg. 2019 Nov 12;: Authors: Rong LQ, Weinsaft JW PMID: 31732467 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 17:19
Related ArticlesNon-activatable mutant of inhibitor of kappa B kinase α (IKKα) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice. Atherosclerosis. 2019 Nov 02;292:23-30 Authors: Tilstam PV, Soppert J, Hemmers C, Harlacher E, Döring Y, van der Vorst EPC, Schulte C, Alampour-Rajabi S, Theelen W, Asare Y, de Winther MPJ, Lawrence T, Bernhagen J, Schober A, Zernecke A, Jankowski J, Weber C, Noels H Abstract BACKGROUND AND AIMS:...
Sun Nov 17, 2019 17:08
Related ArticlesSelf-reported mental health and cortisol activity at 27-28 years of age in individuals born with very low birth weight. Acta Paediatr. 2019 Nov 15;: Authors: Leijon I, Bladh M, Finnström O, Gäddlin PO, Nelson N, Hammar M, ElvarTheodorsson, Sydsjö G Abstract AIM: To assess mental health outcomes of very low birth weight (VLBW, <1500 g) subjects to adulthood, and to examine salivary cortisol and hair cortisol levels and their relation...
Sun Nov 17, 2019 17:02
Related ArticlesOrabase-formulated Gentian Violet Effectively Improved Oral Potentially Malignant Disorder in vitro and in vivo. Biochem Pharmacol. 2019 Nov 13;:113713 Authors: Wang YY, Xiao LY, Wu PC, Chen YK, Lo S, Hu SCS, Chen YH, Chiu CCC, Yuan SSF Abstract Oral cancer is a prevalent cancer in male worldwide. Oral potentially malignant disorders (OMPDs) are the oral mucosa lesions that have high malignant transformation rate to oral cancer. The mainstay...
Sun Nov 17, 2019 16:55
Related ArticlesLocal Failure After Accelerated Partial Breast Irradiation with Intraoperative Radiotherapy with Electrons: An Insight into Management and Outcome from an Italian Multicentric Study. Ann Surg Oncol. 2019 Nov 15;: Authors: Leonardi MC, Tomio L, Radice D, Takanen S, Bonzano E, Alessandro M, Ciabattoni A, Ivaldi GB, Bagnardi V, Alessandro O, Francia CM, Fodor C, Miglietta E, Veronesi P, Galimberti VE, Orecchia R, Tagliaferri L, Vidali C, Massaccesi M, Guenzi...
Sun Nov 17, 2019 16:53
Related ArticlesIntense Expression of EGFR L858R Characterizes the Micropapillary Component and L858R Is Associated with the Risk of Recurrence in pN0M0 Lung Adenocarcinoma with the Micropapillary Component. Ann Surg Oncol. 2019 Nov 15;: Authors: Kishi N, Ito M, Miyata Y, Kanai A, Handa Y, Tsutani Y, Kushitani K, Takeshima Y, Okada M Abstract BACKGROUND: Lung adenocarcinoma with the micropapillary (MP) component poses a higher risk of recurrence even...
Sun Nov 17, 2019 16:53
Related ArticlesContralateral Prophylactic Mastectomy Use After Neoadjuvant Chemotherapy. Ann Surg Oncol. 2019 Nov 15;: Authors: Christian N, Zabor EC, Cassidy M, Flynn J, Morrow M, Gemignani ML Abstract BACKGROUND: Neoadjuvant chemotherapy (NAC) for breast cancer increases breast-conserving surgery (BCS) rates, but many women opt for mastectomy with contralateral prophylactic mastectomy (CPM). Here we evaluate factors associated with CPM use in women...
Sun Nov 17, 2019 16:53
ASO Author Reflections: Location of Primary Colorectal Cancer and Risk of Second Primary Malignancy.
Related ArticlesASO Author Reflections: Location of Primary Colorectal Cancer and Risk of Second Primary Malignancy. Ann Surg Oncol. 2019 Nov 15;: Authors: Broman KK, Parikh AA PMID: 31732943 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 16:53
Related ArticlesOsteochondral lesions of the lateral trochlear ridge: a rare, subtle but important finding on advanced imaging in patients with elbow pain. Skeletal Radiol. 2019 Nov 16;: Authors: Collins MS, Tiegs-Heiden CA Abstract OBJECTIVE: To characterize the radiographic, CT, and MRI appearance of clinically and/or surgically proven osteochondral lesions of the lateral trochlear ridge. MATERIALS AND METHODS: Ten years of medical charts...
Sun Nov 17, 2019 16:51
Related ArticlesPaediatric Enterovirus Meningitis without Cerebrospinal Fluid Pleocytosis. J Infect. 2019 Nov 13;: Authors: Alhazmi A, Lazrek M, Alidjinou EK, Descombes G, Engelmann I, Hober D PMID: 31733234 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 16:44
Related ArticlesHospital clusters of invasive Group B Streptococcal disease: a systematic review. J Infect. 2019 Nov 13;: Authors: Collin SM, Lamb P, Jauneikaite E, Doare KL, Creti R, Berardi A, Heath PT, Sriskandan S, Lamagni T Abstract OBJECTIVES: To characterise outbreaks of invasive Group B Streptococcal (iGBS) disease in hospitals. METHODS: Systematic review using electronic databases to identify studies describing iGBS outbreaks/clusters...
Sun Nov 17, 2019 16:44
Related ArticlesXpert MTB/Ultra assay: handle with care. J Infect. 2019 Nov 13;: Authors: Sarınoğlu RC, Duman N, Ünlü N, Yıldızeli SO, Yagci AK PMID: 31733232 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 16:44
Related ArticlesEgg adaptive mutation patterns of H3N2 human influenza A viruses. J Infect. 2019 Nov 13;: Authors: Wen F, Huang S, Guo J PMID: 31733231 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 16:44
Related ArticlesBioactive lipids as modulators of immune check point inhibitors. Med Hypotheses. 2019 Nov 04;135:109473 Authors: Das UN Abstract It is proposed that arachidonic acid (AA, 20:4 n-6) and other polyunsaturated fatty acids (PUFAs) in combination with immune check point inhibitors and tumor infiltrating lymphocytes (TILs) enhances the activity of T and NK cells and macrophages and thus, aids in the elimination of tumor cells and suppresses...
Sun Nov 17, 2019 16:39
Related ArticlesAre sweetened drinks a gateway to alcohol, opiate and stimulant addiction? Summary of evidence and therapeutic strategies. Med Hypotheses. 2019 Oct 31;135:109469 Authors: de Silva PN Abstract 1. Drinks sweetened with both sugar and artificial additives lead to dopamine release at the nucleus accumbens (NAc) in rat models; the basis of experiences of pleasure in humans, resulting in impulsive binging behaviour at times. 2. Evidence from...
Sun Nov 17, 2019 16:39
Related ArticlesDoes photoperiodism involve a seasonal and non-pathological Warburg effect? Med Hypotheses. 2019 Nov 02;135:109447 Authors: Raitiere MN Abstract The precise means whereby mammals recognize and respond to changing day length so as to adjust their physiology to the seasons (photoperiodism) remains enigmatic. We present a new hypothesis according to which aerobic glycolysis (AG) within selected astrocytic syncytia plays a central role in...
Sun Nov 17, 2019 16:39
Related ArticlesA simple mathematical model for relapsing-remitting multiple sclerosis (RRMS). Med Hypotheses. 2019 Nov 11;135:109478 Authors: Elettreby MF, Ahmed E Abstract Multiple sclerosis is one of the most common autoimmune-related neurological disorders affecting the central nervous system. One of its main properties is dissemination of lesions in time and space. Here, we propose a simple mathematical model to describe the stages of disease progression...
Sun Nov 17, 2019 16:39
Related ArticlesThe association between vitamin deficiency and otolaryngologic diseases: A therapeutic target. Med Hypotheses. 2019 Oct 23;135:109448 Authors: Huang Y, Liu A, Liu L, Wang B, Liang G Abstract Vitamins are indispensable nutrients for metabolism. Adequate vitamin intake plays vital role in physiological processes including embryonic development, cellular and immunity proliferation and differentiation, DNA synthesis and oxidative response....
Sun Nov 17, 2019 16:39
Related ArticlesSerum and saliva total tau protein as a marker for relapsing-remitting multiple sclerosis. Med Hypotheses. 2019 Nov 11;135:109476 Authors: Mirzaii-Dizgah MH, Mirzaii-Dizgah MR, Mirzaii-Dizgah I Abstract Multiple sclerosis (MS) is considered as motor and sensory function loss, which results from demyelination and following axonal lesion. Tau protein interferes in the construction and stabilization of microtubules that are needed for axonal...
Sun Nov 17, 2019 16:39
Related ArticlesRNA-binding protein NONO promotes breast cancer proliferation via posttranscriptional regulation of SKP2 and E2F8. Cancer Sci. 2019 Nov 16;: Authors: Iino K, Mitobe Y, Ikeda K, Takayama KI, Suzuki T, Kawabata H, Suzuki Y, Horie-Inoue K, Inoue S Abstract The majority of breast cancers are primarily hormone-sensitive and could be managed by endocrine therapy, although therapy-resistant or hormone-refractory cancers need alternative treatments....
Sun Nov 17, 2019 16:31
Related ArticlesDeterminants of quality of life in pediatric- and adult-onset multiple sclerosis. Neurology. 2019 Nov 15;: Authors: McKay KA, Ernstsson O, Manouchehrinia A, Olsson T, Hillert J Abstract OBJECTIVE: To evaluate quality of life (QoL), measured by the EQ-5D, in adults with pediatric-onset multiple sclerosis (POMS) or adult-onset multiple sclerosis (AOMS) and explore determinants of QoL in both groups. METHODS: Data were collected...
Sun Nov 17, 2019 16:20
Related ArticlesApathy rating scores and β-amyloidopathy in Parkinson disease patients at risk for cognitive decline. Neurology. 2019 Nov 15;: Authors: Zhou Z, Müller MLTM, Kanel P, Chua J, Kotagal V, Kaufer DI, Albin RL, Frey KA, Bohnen NI Abstract OBJECTIVE: To determine whether β-amyloidopathy correlates with apathy rating scores independently of mood changes and other neurodegenerative processes in Parkinson disease (PD). METHODS: In this...
Sun Nov 17, 2019 16:20
Related ArticlesExome-chip association analysis of intracranial aneurysms. Neurology. 2019 Nov 15;: Authors: van 't Hof FNG, Lai D, van Setten J, Bots ML, Vaartjes I, Broderick J, Woo D, Foroud T, Rinkel GJE, de Bakker PIW, Ruigrok YM Abstract OBJECTIVE: To investigate to what extent low-frequency genetic variants (with minor allele frequencies <5%) affect the risk of intracranial aneurysms (IAs). METHODS: One thousand fifty-six patients...
Sun Nov 17, 2019 16:20
Related ArticlesCortical superficial siderosis and bleeding risk in cerebral amyloid angiopathy: A meta-analysis. Neurology. 2019 Nov 15;: Authors: Charidimou A, Boulouis G, Greenberg SM, Viswanathan A Abstract OBJECTIVE: To assess the association of cortical superficial siderosis (cSS) presence and extent with future bleeding risk in cerebral amyloid angiopathy (CAA). METHODS: This was a meta-analysis of clinical cohorts of symptomatic patients...
Sun Nov 17, 2019 16:20
Related Articlesβ-TrCP1 promotes cell proliferation via TNF-dependent NF-κB activation in diffuse large B cell lymphoma. Cancer Biol Ther. 2019 Nov 15;:1-7 Authors: Cai N, Chen Z, Huang Y, Shao S, Yu H, Wang Y, He S Abstract Diffuse large B cell lymphoma (DLBCL), a heterogeneous group of invasive disease, is the most common type of B-cell non-Hodgkin's lymphomas. The mechanism of its development is closely related to the constitutive activation of NF-κB....
Sun Nov 17, 2019 16:20
21 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Am J Otolaryngol"[jour] These pubmed results were generated on 2019/11/17PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Nov 17, 2019 16:18
Related ArticlesVaccine-related advertising in the Facebook Ad Archive. Vaccine. 2019 Nov 12;: Authors: Jamison AM, Broniatowski DA, Dredze M, Wood-Doughty Z, Khan D, Quinn SC Abstract BACKGROUND: In 2018, Facebook introduced Ad Archive as a platform to improve transparency in advertisements related to politics and "issues of national importance." Vaccine-related Facebook advertising is publicly available for the first time. After measles outbreaks in...
Sun Nov 17, 2019 16:16
Related ArticlesThe effect of time since measles vaccination and age at first dose on measles vaccine effectiveness - A systematic review. Vaccine. 2019 Nov 12;: Authors: Hughes SL, Bolotin S, Khan S, Li Y, Johnson C, Friedman L, Tricco AC, Hahné SJM, Heffernan JM, Dabbagh A, Durrheim DN, Orenstein WA, Moss WJ, Jit M, Crowcroft NS Abstract BACKGROUND: In settings where measles has been eliminated, vaccine-derived immunity may in theory wane more rapidly...
Sun Nov 17, 2019 16:16
Related ArticlesRubella virus-specific humoral immune responses and their interrelationships before and after a third dose of measles-mumps-rubella vaccine in women of childbearing age. Vaccine. 2019 Nov 12;: Authors: Haralambieva IH, Ovsyannikova IG, Kennedy RB, Goergen KM, Grill DE, Chen MH, Hao L, Icenogle J, Poland GA Abstract In the U.S., measles, mumps, and rubella vaccination is recommended as two vaccine doses. A third dose of measles-mumps-rubella...
Sun Nov 17, 2019 16:16
Related ArticlesTeeth extraction revealing mandibular IgA-multiple myeloma recurrence. Oral Oncol. 2019 Nov 12;:104456 Authors: Handra-Luca A PMID: 31732422 [PubMed - as supplied by publisher]
Sun Nov 17, 2019 16:13
Related ArticlesPerfluoroalkyl substances, airways infections, allergy and asthma related health outcomes - implications of gender, exposure period and study design. Environ Int. 2019 Nov 13;134:105259 Authors: Kvalem HE, Nygaard UC, Lødrup Carlsen KC, Carlsen KH, Haug LS, Granum B Abstract INTRODUCTION: Exposure to perfluoroalkyl substances (PFASs) has been inconsistently associated with asthma, allergic diseases and airways infections in early childhood....
Sun Nov 17, 2019 16:05
Related ArticlesThe Protective Effects of Angiotensin-Converting Enzyme Inhibitor against Cecal Ligation and Puncture-Induced Sepsis via Oxidative Stress and Inflammation. Life Sci. 2019 Nov 13;:117051 Authors: Kostakoglu U, Topcu A, Atak M, Tumkaya L, Mercantepe T, Uydu HA Abstract AIMS: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately...
Sun Nov 17, 2019 16:05
Related ArticlesScleredema adultorum of Buschke treated by extracorporeal shock wave therapy. J Eur Acad Dermatol Venereol. 2019 Nov 16;: Authors: Kim DH, Kim JH, Oh YW, Seo BH, Suh HS, Choi YS Abstract Scleredema or scleredema adultorum of Buschke is a rare sclerotic skin disease characterized by diffuse and non-pitting induration and hardening of the skin. It typically involves the face, neck, upper back, and shoulders. Scleredema can be associated...
Sun Nov 17, 2019 16:05
Related ArticlesIBRUTINIB IN THE TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): FIVE YEARS ON. Hematol Oncol. 2019 Nov 15;: Authors: Molica S, Matutes E, Tam C, Polliack A Abstract A major revolution in the treatment of chronic lymphocytic leukemia (CLL) began with the approval of ibrutinib, a first-in-class oral inhibitor of Bruton tyrosine kinase (BTK), for the treatment of relapsed/refractory (R/R) and/or TP53 mutated patients with CLL. However,...
Sun Nov 17, 2019 16:02
Related ArticlesMeasuring vincristine-induced peripheral neuropathy in children with cancer: validation of the Dutch pediatric-modified Total Neuropathy Score. Support Care Cancer. 2019 Nov 16;: Authors: Schouten SM, van de Velde ME, Kaspers GJL, Mokkink LB, van der Sluis IM, van den Bos C, Hartman A, Abbink FCH, van den Berg MH Abstract PURPOSE: The aims were to evaluate the construct validity and reliability of the Dutch version of the pediatric-modified...
Sun Nov 17, 2019 16:02
Related ArticlesInvestigational IGF1R inhibitors in early stage clinical trials for cancer therapy. Expert Opin Investig Drugs. 2019 Nov 15;: Authors: Werner H, Sarfstein R, Bruchim I Abstract Introduction: The insulin-like growth factors (IGF) are a family of secreted peptide hormones with important roles in different cellular and organism functions. The biological activities of the IGFs are mediated by the IGF1 receptor (IGF1R), a cell-surface, tyrosine...
Sun Nov 17, 2019 16:02
Related ArticlesEfficacy of Cancer Immunotherapy: An Umbrella Review of Meta-analyses of Randomized Controlled Trials. Cancers (Basel). 2019 Nov 15;11(11): Authors: Kim JY, Lee KH, Eisenhut M, Vliet HJV, Kronbichler A, Jeong GH, Shin JI, Gamerith G Abstract We conducted a systematic review for evidence of the clinical efficacy of cancer immunotherapies. We searched PubMed from inception to 14 February 2018 for meta-analyses of randomized controlled trials...
Sun Nov 17, 2019 16:02
Related ArticlesTumor Mutational Burden and Efficacy of Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis. Cancers (Basel). 2019 Nov 15;11(11): Authors: Kim JY, Kronbichler A, Eisenhut M, Hong SH, van der Vliet HJ, Kang J, Shin JI, Gamerith G Abstract Tumor mutational burden (TMB) is a genomic biomarker that predicts favorable responses to immune checkpoint inhibitors (ICIs). Here, we set out to assess the predictive value of TMB on...
Sun Nov 17, 2019 16:02
Related ArticlesLow Pre-Treatment Count of Circulating Endothelial Progenitors as a Prognostic Biomarker of the High Risk of Breast Cancer Recurrence. J Clin Med. 2019 Nov 15;8(11): Authors: Rhone P, Bielawski K, Ziołkowska K, Rość D, Ruszkowska-Ciastek B Abstract Neoangiogenesis is mediated by circulating bone marrow-derived endothelial progenitors (circulating EPCs). The aim of the study was the quantification of circulating EPCs from the peripheral...
Sun Nov 17, 2019 16:02
Related ArticlesVitamin D and Gestational Diabetes Mellitus: Is There a Link? Antioxidants (Basel). 2019 Oct 25;8(11): Authors: Rizzo G, Garzon S, Fichera M, Panella MM, Catena U, Schiattarella A, de Franciscis P, Vilos G, Tesarik J, Török P, Grosso G Abstract Gestational diabetes mellitus (GDM) is a very common condition among pregnant women worldwide with important metabolic implications on the mother and the offspring. Vitamin D status has been suggested...
Sun Nov 17, 2019 16:02
Related ArticlesATP6V1B1 recurrent mutations in Algerian deaf patients associated with renal tubular acidosis. Int J Pediatr Otorhinolaryngol. 2019 Nov 09;129:109772 Authors: Dahmani M, Talbi S, Ammar-Khodja F, Ouhab S, Boudjenah F, Djebbar M, Bonnet C, Petit C Abstract Hereditary distal renal tubular acidosis (dRTA) is a rare disorder characterized by metabolic acidosis due to impaired renal acid excretion. To date, three genes (ATP6V1B1, ATP6V0A4 and...
Sun Nov 17, 2019 15:56
Related ArticlesAdvanced practice providers and children's hospital-based pediatric otolarynology practices. Int J Pediatr Otorhinolaryngol. 2019 Nov 07;129:109770 Authors: Chan KH, Dinwiddie JK, Ahuja GS, Bennett EC, Brigger MT, Chi DH, Choo DI, Cunningham MJ, Elluru RG, Giannoni CM, Goudy SL, Koempel JA, MacArthur CJ, Malone B, Messner AH, Mitchell RB, Park AH, Richter GT, Rosbe KW, Shah UK, Sie KCY, Smith RJ, Sulman CG, Thompson JW, Thorne MC, Wei JL, Wetmore RF, White...
Sun Nov 17, 2019 15:56
Related ArticlesResection of inverted papilloma in nasal cavity with transseptal access and crossing multiple incisions minimizes bleeding and reveals the tumor pedicle. Auris Nasus Larynx. 2019 Nov 12;: Authors: Omura K, Nomura K, Aoki S, Hosokawa Y, Tanaka Y, Otori N, Kojima H Abstract OBJECTIVE: Sinonasal inverted papilloma can be resected endoscopically, but has a risk of recurrence. This risk can be minimized by identifying the pedicle of the tumor...
Sun Nov 17, 2019 15:53
Related ArticlesUtility of acoustic pharyngometry for screening of obstructive sleep apnea. Auris Nasus Larynx. 2019 Nov 12;: Authors: Kim BY, Cho JH, Kim DH, Kim SW, Kim SW, Kim BG, Park YJ Abstract OBJECTIVE: To determine whether combining acoustic pharyngometric parameters with cephalometric and clinical parameters could improve the predictive power for significant obstructive sleep apnea (OSA) in a Korean population. METHODS: A total of...
Sun Nov 17, 2019 15:53
Related ArticlesAssessment of risk factors associated with development of oronasal fistula as a late complication after carbon-ion radiotherapy for head and neck cancer. Radiother Oncol. 2019 Nov 13;144:53-58 Authors: Bhattacharyya T, Koto M, Ikawa H, Hayashi K, Hagiwara Y, Tsuji H Abstract BACKGROUND: Oronasal fistulae (ONF) are one of the rare but serious complications of conventional photon radiotherapy. This study aimed to identify the risk factors...
Sun Nov 17, 2019 15:48
Related ArticlesOrbital metastases from neuroendocrine neoplasms: clinical implications and outcomes. Endocrine. 2019 Nov 15;: Authors: Kamieniarz L, Armeni E, O'Mahony LF, Leigh C, Miah L, Narayan A, Bhatt A, Cox N, Mandair D, Navalkissoor S, Caplin M, Toumpanakis C Abstract PURPOSE: Neuroendocrine neoplasms (NENs) may rarely metastasise to the orbit. Published data on epidemiology, incidence and preferred treatment is limited. We present the largest...
Sun Nov 17, 2019 15:48
Related ArticlesSocial determinants of health and survivorship in parotid cancer: An analysis of the National Cancer Database. Am J Otolaryngol. 2019 Oct 18;:102307 Authors: Stubbs VC, Rajasekaran K, Cannady SB, Newman JG, Ibrahim SA, Brant JA Abstract BACKGROUND: Given the rarity of parotid cancer, there is relatively few data published regarding outcomes. Utilizing the large sample population of the National Cancer Database (NCDB), we aim to examine...
Sun Nov 17, 2019 15:48
Related ArticlesRole of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models. Cancers (Basel). 2019 Oct 25;11(11): Authors: O'Brien A, Zhou T, Tan C, Alpini G, Glaser S Abstract Liver cancer is a devastating cancer that ranges from relatively rare (around 2% of all cancers in the United States) to commonplace (up to 50% of cancers in underdeveloped countries). Depending upon the stage of pathogenesis, prognosis, or functional...
Sun Nov 17, 2019 15:48
Related ArticlesTumor and Cerebrospinal Fluid microRNAs in Primary Central Nervous System Lymphomas. Cancers (Basel). 2019 Oct 25;11(11): Authors: Zajdel M, Rymkiewicz G, Sromek M, Cieslikowska M, Swoboda P, Kulinczak M, Goryca K, Bystydzienski Z, Blachnio K, Ostrowska B, Borysiuk A, Druzd-Sitek A, Walewski J, Chechlinska M, Siwicki JK Abstract Primary central nervous system lymphoma (PCNSL) is a rare, highly aggressive, extranodal form of non-Hodgkin...
Sun Nov 17, 2019 15:48
Related ArticlesAn observational analysis of meal patterns in overweight and obese pregnancy: exploring meal pattern behaviours and the association with maternal and fotal health measures. Ir J Med Sci. 2019 Nov 15;: Authors: Ainscough KM, Kennelly MA, Lindsay KL, O'Brien EC, O'Sullivan EJ, Mehegan J, Gibney ER, McAuliffe FM Abstract BACKGROUND: Nutrient intakes are known to be poorer among pregnant women with raised body mass index (BMI) than those...
Sun Nov 17, 2019 15:47
Related ArticlesComparison of analgesic effect, knee joint function recovery, and safety profiles between pre-operative and post-operative administrations of meloxicam in knee osteoarthritis patients who underwent total knee arthroplasty. Ir J Med Sci. 2019 Nov 15;: Authors: Shao Y, Zhao X, Zhai Y, Yang J, Wang S, Liu L, Wang J Abstract AIMS: This study aimed to compare the efficacy and safety of pre-operative and post-operative meloxicam administration...
Sun Nov 17, 2019 15:47
Related ArticlesSystemic Artery Aneurysms and Kawasaki Disease. Pediatrics. 2019 Nov 15;: Authors: Zhao QM, Chu C, Wu L, Liang XC, Sun SN, He L, Zhao L, Wang F, Huang GY, Niu C, Liu F Abstract BACKGROUND: Coronary artery aneurysms (CAAs) are a well-known complication of Kawasaki disease (KD), but there are no data on incidence or outcomes of systemic artery aneurysms (SAAs) in the current era. METHODS: From April 1, 2016, to March 31, 2019,...
Sun Nov 17, 2019 15:45
Related ArticlesChronic, Gross Hematuria Caused by Idiopathic Ureteric Stricture. Pediatrics. 2019 Nov 15;: Authors: Myette RL, Acker A Abstract An otherwise healthy, 10-year-old boy presented with chronic, gross hematuria. This persisted daily for 5 years despite extensive multidisciplinary workup with renal biopsy and resulted in severe iron deficiency anemia. The extensive workup and requirement for routine follow-up, investigations, and procedures...
Sun Nov 17, 2019 15:45
Related ArticlesTurbinate loss from non-inflammatory sinonasal surgery does not correlate with poor sinonasal function. Am J Otolaryngol. 2019 Oct 17;:102316 Authors: Wong EH, Orgain CA, Sansoni ER, Alvarado R, Grayson J, Kalish L, Sacks R, Harvey RJ Abstract OBJECTIVE: The impact of turbinate resection on nasal function remains a controversial topic. In surgery for inflammatory sinonasal disease, turbinate resection is often avoided. In contrast, turbinate...
Sun Nov 17, 2019 15:40
Related ArticlesPrognostic role of blood eosinophil and basophil levels in allergic fungal rhinosinusitis (AFRS). Am J Otolaryngol. 2019 Sep 13;:102301 Authors: Brescia G, Franz L, Alessandrini L, Parrino D, Barion U, Marioni G Abstract PURPOSE: Allergic fungal rhinosinusitis (AFRS) forms a subset of chronic rhinosinusitis with nasal polyps (CRSwNP) that is mainly characterized by eosinophilic nasal polyps, allergic mucin detected in the sinuses at surgery,...
Sun Nov 17, 2019 15:40
Related ArticlesThe Differential Impact of SRC Expression on the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019 Oct 25;11(11): Authors: Hermida-Prado F, Granda-Díaz R, Del-Río-Ibisate N, Villaronga MÁ, Allonca E, Garmendia I, Montuenga LM, Rodríguez R, Vallina A, Alvarez-Marcos C, Rodrigo JP, García-Pedrero JM Abstract Aberrant SRC expression and activation is frequently detected in multiple cancers, and hence,...
Sun Nov 17, 2019 15:31
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