Atmosphere, Vol. 10, Pages 677: Interdecadal Variations of the Midlatitude Ozone Valleys in Summer Atmosphere doi: 10.3390/atmos10110677 Authors: Zhiming Zhang Jian Rao Dong Guo Wenhui Zhang Liping Li Zhou Tang Chunhua Shi Yucheng Su Fuying Zhang Using the ERA-Interim total column ozone data, the spatial distributions of the long-term mean of the global total ozone in summer are analyzed. The results demonstrate that there are three midlatitude ozone “valleys”...
Sat Nov 02, 2019 02:00
Biomolecules, Vol. 9, Pages 690: On the Neuroprotective Effects of Naringenin: Pharmacological Targets, Signaling Pathways, Molecular Mechanisms, and Clinical Perspective Biomolecules doi: 10.3390/biom9110690 Authors: Nouri Fakhri El-Senduny Sanadgol Abd-ElGhani Farzaei Chen As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases (NDs) affect millions of people worldwide, and are on the rise. NDs are known as the gradual loss of...
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Biomolecules, Vol. 9, Pages 689: Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells Biomolecules doi: 10.3390/biom9110689 Authors: Janitschke Nelke Lauer Regner Winkler Thiel Grimm Hartmann Grimm Methylxanthines (MTX) are alkaloids derived from the purine-base xanthine. Whereas especially caffeine, the most prominent known MTX, has been formerly assessed to be detrimental, this point of view has changed substantially. MTXs...
Sat Nov 02, 2019 02:00
Biomolecules, Vol. 9, Pages 688: Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As a Novel Inhibitor of HMGA2 in Colorectal Cancer Biomolecules doi: 10.3390/biom9110688 Authors: Yu-Min Huang Chia-Hsiung Cheng Shiow-Lin Pan Pei-Ming Yang Ding-Yen Lin Kuen-Haur Lee Human high-mobility group A2 (HMGA2) encodes for a non-histone chromatin protein which influences a variety of biological processes, including the cell cycle process, apoptosis,...
Sat Nov 02, 2019 02:00
Biomolecules, Vol. 9, Pages 687: Coupled Response of Membrane Hydration with Oscillating Metabolism in Live Cells: An Alternative Way to Modulate Structural Aspects of Biological Membranes? Biomolecules doi: 10.3390/biom9110687 Authors: Luis A. Bagatolli Roberto P. Stock Lars F. Olsen We propose that active metabolic processes may regulate structural changes in biological membranes via the physical state of cell water. This proposition is based on recent results obtained from our...
Sat Nov 02, 2019 02:00
Brain Sciences, Vol. 9, Pages 307: More than Meets the Mind’s Eye? Preliminary Observations Hint at Heterogeneous Alpha Neuromarkers for Visual Attention Brain Sciences doi: 10.3390/brainsci9110307 Authors: Emmanuelle Tognoli With their salient power distribution and privileged timescale for cognition and behavior, brainwaves within the 10 Hz band are special in human waking electroencephalography (EEG). From the inception of electroencephalographic technology, the contribution of alpha...
Sat Nov 02, 2019 02:00
Brain Sciences, Vol. 9, Pages 308: The Practical Use of White Cell Inflammatory Biomarkers in Prediction of Postoperative Delirium after Cardiac Surgery Brain Sciences doi: 10.3390/brainsci9110308 Authors: Kotfis Ślozowska Safranow Szylińska Listewnik : Introduction: Postoperative delirium (POD) is associated with unfavorable outcomes. It may result from neuroinflammation and oxidative stress. The aim of this study was to evaluate the role of routinely available inflammatory...
Sat Nov 02, 2019 02:00
Brain Sciences, Vol. 9, Pages 306: Insomnia Symptoms among African-American Older Adults in Economically Disadvantaged Areas of South Los Angeles Brain Sciences doi: 10.3390/brainsci9110306 Authors: Mohsen Bazargan Nadia Mian Sharon Cobb Roberto Vargas Shervin Assari Background. Although psychosocial and health factors impact insomnia symptoms, less is known about these effects in economically disadvantaged African-American older adults. Aims. This study investigated social...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1716: Balancing STAT Activity as a Therapeutic Strategy Cancers doi: 10.3390/cancers11111716 Authors: Polak Chernosky Smigiel Tamagno Jackson Driven by dysregulated IL-6 family member cytokine signaling in the tumor microenvironment (TME), aberrant signal transducer and activator of transcription (STAT3) and (STAT5) activation have been identified as key contributors to tumorigenesis. Following transformation, persistent STAT3 activation drives...
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Cancers, Vol. 11, Pages 1717: Loss of FBXO9 Enhances Proteasome Activity and Promotes Aggressiveness in Acute Myeloid Leukemia Cancers doi: 10.3390/cancers11111717 Authors: Hynes-Smith Swenson Vahle Wittorf Caplan Amador Hyde Buckley The hematopoietic system is maintained throughout life by stem cells that are capable of differentiating into all hematopoietic lineages. An intimate balance between self-renewal, differentiation, and quiescence is required to...
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Cancers, Vol. 11, Pages 1715: Conversion Surgery with HIPEC for Peritoneal Oligometastatic Gastric Cancer Cancers doi: 10.3390/cancers11111715 Authors: Mielko Rawicz-Pruszyński Skórzewska Ciseł Pikuła Kwietniewska Gęca Sędłak Kurylcio Polkowski Peritoneal metastases (PM) of gastric cancer (GC) are characterized by a particularly poor prognosis, with median survival time of 6 months, and virtually no 5-year survival reported. Conversion therapy for...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1714: Immunohistochemical and Molecular Features of Melanomas Exhibiting Intratumor and Intertumor Histomorphologic Heterogeneity Cancers doi: 10.3390/cancers11111714 Authors: Haider A. Mejbel Sri Krishna C. Arudra Dinesh Pradhan Carlos A. Torres-Cabala Priyadharsini Nagarajan Michael T. Tetzlaff Jonathan L. Curry Doina Ivan Dzifa Y. Duose Raja Luthra Victor G. Prieto Leomar Y. Ballester Phyu P. Aung Melanoma is a heterogeneous...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1713: The Lung Immune Prognostic Index Discriminates Survival Outcomes in Patients with Solid Tumors Treated with Immune Checkpoint Inhibitors Cancers doi: 10.3390/cancers11111713 Authors: Meyers Stukalin Vallerand Lewinson Suo Dean North Pabani Cheng Heng Bebb Morris Immune checkpoint inhibitors (ICI) have revolutionized the treatment landscape of several solid tumor types. However, as patient outcomes are heterogeneous,...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1710: CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary Cancers doi: 10.3390/cancers11111710 Authors: Bai Zhu Coffman Vlad Schwartz Elishaev Drapkin Buckanovich : Most high‐grade serous ovarian cancers (HGSCs) initiate from the fallopian tube epithelium and then metastasize to the ovary and throughout the abdomen. Genomic analyses suggest that most HGSCs seed the ovary prior to abdominal...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1711: STAT3 Dysregulation in Mature T and NK Cell Lymphomas Cancers doi: 10.3390/cancers11111711 Authors: Seffens Herrera Tegla Buus Hymes Ødum Geskin Koralov Abstract: T cell lymphomas comprise a distinct class of non-Hodgkin’s lymphomas, which include mature T and natural killer (NK) cell neoplasms. While each malignancy within this group is characterized by unique clinicopathologic features, dysregulation in the Janus...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1709: Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom Cancers doi: 10.3390/cancers11111709 Authors: Curto Aklan Mulder Mils Schmidt Lamprecht Peller Wessalowski Lindner Fietkau Zips Bellizzi van Holthe Franckena Paulides van Rhoon Clinical outcome of hyperthermia depends...
Sat Nov 02, 2019 02:00
Cancers, Vol. 11, Pages 1712: Potential of Melatonin as Adjuvant Therapy of Oral Cancer in the Era of Epigenomics Cancers doi: 10.3390/cancers11111712 Authors: Capote-Moreno Ramos Egea López-Muñoz Gil-Martín Romero The wide variety of epigenetic controls available is rapidly expanding the knowledge of molecular biology even overflowing it. At the same time, it can illuminate unsuspected ways of understanding the etiology of cancer. New emerging therapeutic horizons,...
Sat Nov 02, 2019 02:00
Cells, Vol. 8, Pages 1379: The Impact of Oxidative Stress on Ribosomes: From Injury to Regulation Cells doi: 10.3390/cells8111379 Authors: Natalia Shcherbik Dimitri G. Pestov The ribosome is a complex ribonucleoprotein-based molecular machine that orchestrates protein synthesis in the cell. Both ribosomal RNA and ribosomal proteins can be chemically modified by reactive oxygen species, which may alter the ribosome′s functions or cause a complete loss of functionality. The...
Sat Nov 02, 2019 02:00
Diagnostics, Vol. 9, Pages 173: mRNA Detection in Anal Cytology: A Feasible Approach for Anal Cancer Screening in Men Who Have Sex with Men Living With HIV Diagnostics doi: 10.3390/diagnostics9040173 Authors: Pino Martí Gaber Svanholm-Barrie Rodríguez-Carunchio Rodriguez-Trujillo Carreras Fuertes Barnadas Marimón Blanco Persing Torné Ordi There is growing interest in anal cancer screening strategies. However, cytological/molecular...
Sat Nov 02, 2019 02:00
Foods, Vol. 8, Pages 544: Development, Characterization, and Bioactivity of Non-Dairy Kefir-Like Fermented Beverage Based on Flaxseed Oil Cake Foods doi: 10.3390/foods8110544 Authors: Łukasz Łopusiewicz Emilia Drozłowska Paulina Siedlecka Monika Mężyńska Artur Bartkowiak Monika Sienkiewicz Hanna Zielińska-Bliźniewska Paweł Kwiatkowski Flaxseed oil cake (FOC) was evaluated as a potential substrate for the production of a novel kefir-like fermented beverage. Three...
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Foods, Vol. 8, Pages 543: Bioactivity-Guided Fractionation and NMR-Based Identification of the Immunomodulatory Isoflavone from the Roots of Uraria crinita (L.) Desv. ex DC Foods doi: 10.3390/foods8110543 Authors: Ping-Chen Tu Chih-Ju Chan Yi-Chen Liu Yueh-Hsiung Kuo Ming-Kuem Lin Meng-Shiou Lee Uraria crinita is used as a functional food ingredient. Little is known about the association between its immunomodulatory activity and its metabolites. We applied a precise strategy...
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Foods, Vol. 8, Pages 542: Characterization of Listeria Monocytogenes Originating from the Spanish Meat-Processing Chain Foods doi: 10.3390/foods8110542 Authors: Rosa Capita Amanda Felices-Mercado Camino García-Fernández Carlos Alonso-Calleja Using agglutination techniques, 118 Listeria monocytogenes isolates from red meat and poultry were serotyped. Strains were ascribed to the serotypes 4b/4e (44.1% of the strains), 1/2 (a, b or c; 28.0%), 4c (6.8%), 4d/4e (5.9%) and 3 (a,...
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Foods, Vol. 8, Pages 541: Optimization of a Microplate Assay for Generating Listeria Monocytogenes, E. Coli O157:H7, and Salmonella Biofilms and Enzymatic Recovery for Enumeration Foods doi: 10.3390/foods8110541 Authors: Manish Aryal Preetty Pranatharthiharan Peter M. Muriana Biofilms enable the persistence of pathogens in food processing environments. Sanitizing agents are needed that are effective against pathogens entrapped in biofilms that are more difficult to inactivate than...
Sat Nov 02, 2019 02:00
Foods, Vol. 8, Pages 540: Characterization of Maltase and Sucrase Inhibitory Constituents from Rhodiola crenulata Foods doi: 10.3390/foods8110540 Authors: Wen-Tai Li Yu-Hsuan Chuang Jung-Feng Hsieh The inhibitory properties of epicatechin-(4β,8)-epicatechingallate (B2-3’-O-gallate), epicatechin gallate (ECG), and epicatechin (EC) isolated from Rhodiola crenulata toward maltase and sucrase were investigated. The half-maximal inhibitory concentration (IC50) values...
Sat Nov 02, 2019 02:00
Foods, Vol. 8, Pages 539: Evaluation of Continuous UVC Treatments and its Combination with UHPH on Spores of Bacillus subtilis in Whole and Skim Milk Foods doi: 10.3390/foods8110539 Authors: María Martinez-Garcia Jezer N. Sauceda-Gálvez Idoia Codina-Torrella Mª Manuela Hernández-Herrero Ramón Gervilla Artur X. Roig-Sagués The aim of this study was to evaluate the effectiveness of different UVC treatments, alone or in combination with ultra-high pressure homogenization...
Sat Nov 02, 2019 02:00
IJERPH, Vol. 16, Pages 4269: Predicting the Swallow-Related Quality of Life of the Elderly Living in a Local Community Using Support Vector Machine International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214269 Authors: Haewon Byeon Background and Objectives: This study developed a support vector machine (SVM) algorithm-based prediction model with considering influence factors associated with the swallowing quality-of-life as the predictor variables and...
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IJERPH, Vol. 16, Pages 4270: Evaluation of the Effectiveness of Mobile App-Based Stress-Management Program: A Randomized Controlled Trial International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214270 Authors: Won Ju Hwang Hyun Hee Jo Improving mental healthcare using mobile apps might be an effective way to increase interest in mental health and respond to the demand for better psychological health. However, few studies have investigated the effectiveness...
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IJERPH, Vol. 16, Pages 4268: Determinants of Hurricane Evacuation from a Large Representative Sample of the U.S. Gulf Coast International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214268 Authors: Ibraheem M. Karaye Jennifer A. Horney David P. Retchless Ashley D. Ross Exposure to natural disasters like hurricanes negatively impacts the mental and physical health of populations, and evacuation is an important step taken to prevent these adverse health...
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IJERPH, Vol. 16, Pages 4267: The Association between Difficulty Seeing and Physical Activity among 17,777 Adults Residing in Spain International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214267 Authors: Guillermo F. López-Sánchez Igor Grabovac Damiano Pizzol Lin Yang Lee Smith This is the first representative population-based study exploring the association between difficulty seeing (i.e., low vision) and physical activity in Spain. Cross-sectional...
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IJERPH, Vol. 16, Pages 4265: Exploring Determinants of Population Ageing in Northeast China: From a Socio-Economic Perspective International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214265 Authors: Yang Zhao Fan The paper aims to examine the population ageing process in northeast China, typically perceived as a region experiencing dramatic demographic change and socio-economic slowdown that is much deeper and more significant compared to other...
Sat Nov 02, 2019 02:00
IJERPH, Vol. 16, Pages 4266: Psychosocial and Physiological Health Outcomes of Green Exercise in Children and Adolescents—A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214266 Authors: Mnich Weyland Jekauc Schipperijn Both physical activity (PA) and nature exposure are associated with several youth health benefits. However, the health outcomes when being physically active in nature, called Green Exercise (GE), are...
Sat Nov 02, 2019 02:00
IJMS, Vol. 20, Pages 5474: Transforming Growth Factor Beta 3-Loaded Decellularized Equine Tendon Matrix for Orthopedic Tissue Engineering International Journal of Molecular Sciences doi: 10.3390/ijms20215474 Authors: Susanne Pauline Roth Walter Brehm Claudia Groß Patrick Scheibe Susanna Schubert Janina Burk Transforming growth factor beta 3 (TGFβ3) promotes tenogenic differentiation and may enhance tendon regeneration in vivo. This study aimed to apply TGFβ3...
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IJMS, Vol. 20, Pages 5473: Metabolic Profile, Bioavailability and Toxicokinetics of Zearalenone-14-Glucoside in Rats after Oral and Intravenous Administration by Liquid Chromatography High-Resolution Mass Spectrometry and Tandem Mass Spectrometry International Journal of Molecular Sciences doi: 10.3390/ijms20215473 Authors: Feifei Sun Haiguang Tan Yanshen Li Marthe De Boevre Sarah De Saeger Jinhui Zhou Yi Li Zhenghua Rao Shupeng Yang Huiyan Zhang Zearalenone-14-glucoside...
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IJMS, Vol. 20, Pages 5472: The Blood–Brain Barrier and Its Intercellular Junctions in Age-Related Brain Disorders International Journal of Molecular Sciences doi: 10.3390/ijms20215472 Authors: Laura Costea Ádám Mészáros Hannelore Bauer Hans-Christian Bauer Andreas Traweger Imola Wilhelm Attila E. Farkas István A. Krizbai With age, our cognitive skills and abilities decline. Maybe starting as an annoyance, this decline can become a major impediment to normal daily...
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IJMS, Vol. 20, Pages 5471: Impact of the Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells (AD-SVFs) and Human Adipose-Derived Mesenchymal Stem Cells (AD-MSCs): Enzymatic Digestion Versus Mechanical Centrifugation International Journal of Molecular Sciences doi: 10.3390/ijms20215471 Authors: Pietro Gentile Claudio Calabrese Barbara De Angelis Jacopo Pizzicannella Ashutosh Kothari Simone Garcovich Autologous therapies using adipose-derived...
Sat Nov 02, 2019 02:00
IJMS, Vol. 20, Pages 5470: Allelic Variants for Candidate Nitrogen Fixation Genes Revealed by Sequencing in Red Clover (Trifolium pratense L.) International Journal of Molecular Sciences doi: 10.3390/ijms20215470 Authors: Oldřich Trněný David Vlk Eliška Macková Michaela Matoušková Jana Řepková Jan Nedělník Jan Hofbauer Karel Vejražka Hana Jakešová Jan Jansa Lubomír Piálek Daniela Knotová Plant–rhizobia symbiosis can activate key genes involved...
Sat Nov 02, 2019 02:00
IJNS, Vol. 5, Pages 39: Development of a Multiplex real-time PCR Assay for the Newborn Screening of SCID, SMA, and XLA International Journal of Neonatal Screening doi: 10.3390/ijns5040039 Authors: Cristina Gutierrez-Mateo Anne Timonen Katja Vaahtera Markku Jaakkola David M Hougaard Jonas Bybjerg-Grauholm Marie Baekvad-Hansen Dea Adamsen Galina Filippov Stephanie Dallaire David Goldfarb Daniel Schoener Rongcong Wu Numerous studies have shown evidence...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1859: Methotrexate Restores CD73 Expression on Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis Patients and May Contribute to Its Anti-Inflammatory Effect through Ado Production Journal of Clinical Medicine doi: 10.3390/jcm8111859 Authors: Bossennec Rodriguez Hubert Di-Roio Machon Guitton Battiston-Montagne Couturier Marotte Caux Coury Ménétrier-Caux Objectives: Th1.17 are highly polyfunctional, potentially harmful...
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JCM, Vol. 8, Pages 1857: Early Lyme Borreliosis in Patients Treated with Tumour Necrosis Factor-Alfa Inhibitors Journal of Clinical Medicine doi: 10.3390/jcm8111857 Authors: Vera Maraspin Petra Bogovič Tereza Rojko Katarina Ogrinc Eva Ružić-Sabljić Franc Strle The study evaluated the course and outcome of erythema migrans in patients receiving tumour necrosis factor-alpha (TNF-α) inhibitors. Among 4157 adults diagnosed with erythema migrans in the period 2009–2018,...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1853: Biofilm Formation by Staphylococcus aureus Clinical Isolates is Differentially Affected by Glucose and Sodium Chloride Supplemented Culture Media Journal of Clinical Medicine doi: 10.3390/jcm8111853 Authors: Harshad Lade Joon Hyun Park Sung Hee Chung In Hee Kim Jung-Min Kim Hwang-Soo Joo Jae-Seok Kim Staphylococcus aureus (S. aureus) causes persistent biofilm-related infections. Biofilm formation by S. aureus is affected by the culture conditions...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1856: The Role of Protein SUMOylation in the Pathogenesis of Atherosclerosis Journal of Clinical Medicine doi: 10.3390/jcm8111856 Authors: Dehnavi Sadeghi Penson Banach Jamialahmadi Sahebkar Atherosclerosis is a progressive, inflammatory cardiovascular disorder characterized by the development of lipid-filled plaques within arteries. Endothelial cell dysfunction in the walls of blood vessels results in an increase in vascular permeability, alteration...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1858: Analysis of Perioperative Platelet Indices and Their Prognostic Value in Head and Neck Cancer Patients Treated with Surgery and Postoperative Radiotherapy: A Retrospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm8111858 Authors: Jank Haas Dunkler Campion Brkic Heiduschka Kadletz Objectives: Activated platelets might play an important role in tumor progression. Mean platelet volume (MPV) has been used as a surrogate marker...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1847: Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy Journal of Clinical Medicine doi: 10.3390/jcm8111847 Authors: Kim Lee Song Park Gadhe Choi Lee Pae Kim Ye Persistently activated STAT3 is a promising target for a new class of anticancer drug development and cancer therapy, as it is associated with tumor initiation, progression, malignancy, drug resistance, cancer stem...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1855: Conditional Controlled Light/Dark Cycle Influences Exercise-Induced Benefits in a Rat Model with Osteoarthritis: In Vitro and In Vivo Study Journal of Clinical Medicine doi: 10.3390/jcm8111855 Authors: Hong Lee Choi Jin Won Hong Physical exercise has long been recommended as a treatment for osteoarthritis (OA), though its effects vary based on the exercise protocol. Here, we examined whether environmental lighting conditions influence the...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1848: Progressive Pulmonary Artery Dilatation is Associated with Type B Aortic Dissection in Patients with Marfan Syndrome Journal of Clinical Medicine doi: 10.3390/jcm8111848 Authors: Christel Brouwer Haldun Bulut Willemijn van Gemert Alexander HJ Staal Kim Cortenbach Miranda Snoeren Robin Nijveldt Anthonie Duijnhouwer Bart L Loeys Niels van Royen Janneke Timmermans Roland RJ van Kimmenade Objective: Marfan syndrome (MFS) is a connective...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1852: Evaluation of Concomitant Orbital Floor Fractures in Patients with Head Trauma Using Conventional Head CT Scan: A Retrospective Study at a Level II Trauma Center Journal of Clinical Medicine doi: 10.3390/jcm8111852 Authors: Li-Kuo Huang Hsi-Feng Tu Liang-De Jiang Ying-Yuan Chen Chih-Yuan Fu Background: Patients with head trauma may have concomitant orbital floor fractures (OFFs). The objective of our study was to determine the specific CT findings...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1851: Validity and Reliability of a New Optoelectronic System for Measuring Active Range of Motion of Upper Limb Joints in Asymptomatic and Symptomatic Subjects Journal of Clinical Medicine doi: 10.3390/jcm8111851 Authors: Rodrigo Martín-San Agustín Jose A. García-Vidal German Cánovas-Ambit Aurelio Arenas-Della Vecchia Manuel López-Nicolás Francesc Medina-Mirapeix The aim of this study was to evaluate the validity of the Veloflex infrared dynamic angle-meter...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1849: Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis Journal of Clinical Medicine doi: 10.3390/jcm8111849 Authors: Hyo Jung Shin Hyewon Park Nara Shin Hyeok Hee Kwon Yuhua Yin Jeong-Ah Hwang Hee-Jung Song Jinhyun Kim Dong Woon Kim Jaewon Beom Cartilage loss is a central event in the pathogenesis of osteoarthritis (OA), though other than mechanical loading, the biochemical mechanisms underlying...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1850: Mitotane Concentrations Influence the Risk of Recurrence in Adrenocortical Carcinoma Patients on Adjuvant Treatment Journal of Clinical Medicine doi: 10.3390/jcm8111850 Authors: Soraya Puglisi Anna Calabrese Vittoria Basile Filippo Ceccato Carla Scaroni Chiara Simeoli Massimo Torlontano Salvatore Cannavò Giorgio Arnaldi Antonio Stigliano Pasqualino Malandrino Laura Saba Barbara Altieri Silvia Della Casa Paola Perotti Paola...
Sat Nov 02, 2019 02:00
JCM, Vol. 8, Pages 1854: Loop Diuretic Administration in Patients with Acute Heart Failure and Reduced Systolic Function: Effects of Different Intravenous Diuretic Doses and Diuretic Response Measurements Journal of Clinical Medicine doi: 10.3390/jcm8111854 Authors: Gaetano Ruocco Mauro Feola Ranuccio Nuti Lorenzo Luschi Isabella Evangelista Alberto Palazzuoli Background: Despite the fact that loop diuretics are a landmark in acute heart failure (AHF) treatment, few trials...
Sat Nov 02, 2019 02:00
Metabolites, Vol. 9, Pages 264: Seasonal Variations and Interspecific Differences in Metabolomes of Freshwater Fish Tissues: Quantitative Metabolomic Profiles of Lenses and Gills Metabolites doi: 10.3390/metabo9110264 Authors: Tsentalovich Yanshole Yanshole Zelentsova Melnikov Sagdeev This work represents the first comprehensive report on quantitative metabolomic composition of tissues of pike-perch (Sander lucioperca) and Siberian roach (Rutilus rutilus lacustris)....
Sat Nov 02, 2019 02:00
Metabolites, Vol. 9, Pages 263: Long-Term Exposure of Psoralen and Isopsoralen Induced Hepatotoxicity and Serum Metabolites Profiles Changes in Female Rats Metabolites doi: 10.3390/metabo9110263 Authors: Yu Wang Yu Lu Jiang Zhou :Pre-clinical safety evaluation of traditional medicines is imperative because of the universality of drug-induced adverse reactions. Psoralen and isopsoralen are the major active molecules and quality-control components of a traditional...
Sat Nov 02, 2019 02:00
Microorganisms, Vol. 7, Pages 522: HP1717 Contributes to Streptococcus suis Virulence by Inducing an Excessive Inflammatory Response and Influencing the Biosynthesis of the Capsule Microorganisms doi: 10.3390/microorganisms7110522 Authors: Liu Zhang Xu Huang Zhu Zhang Sun Jin Streptococcus suis 2 (SS2) is an important zoonotic pathogen that substantially harms the swine industry and poses threats to human health. Excessive inflammation is considered to be...
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Molecules, Vol. 24, Pages 3976: Differential Cytotoxic Potential of Acridocarpus orientalis Leaf and Stem Extracts with the Ability to Induce Multiple Cell Death Pathways Molecules doi: 10.3390/molecules24213976 Authors: Sameera Omar Mohammed Saeed Balhamar Neena Gopinathan Panicker Shaima Akhlaq Mohammed Mansoor Qureshi Waqar Ahmad Najeeb Ur Rehman Liaqat Ali Ahmed Al-Harrasi Javid Hussain Farah Mustafa This study systematically analyzed the anticancer potential...
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Molecules, Vol. 24, Pages 3977: Effects of Temperature on Bending Properties of Three-Dimensional and Five-Directional Braided Composite Molecules doi: 10.3390/molecules24213977 Authors: Li Jia Pei Wan Li Wu The bending properties of three-dimensional (3Dim) and five-directional (5Dir) braided/epoxy resin composites at room temperature, 90 °C, 110 °C, and 150 °C and heating for 0.25 h, 10 h, and 30 h, respectively, were studied. The effect...
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Molecules, Vol. 24, Pages 3975: Automated Stopped-Flow Fluorimetric Sensor for Biologically Active Adamantane Derivatives Based on Zone Fluidics Molecules doi: 10.3390/molecules24213975 Authors: Paraskevas D. Tzanavaras Sofia Papadimitriou Constantinos K. Zacharis A zone-fluidics (ZF) based automated fluorimetric sensor for the determination of pharmaceutically active adamantine derivatives, i.e., amantadine (AMA), memantine (MEM) and rimantadine (RIM) is reported. Discrete zones...
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Molecules, Vol. 24, Pages 3974: Morphological, Physicochemical and FTIR Spectroscopic Properties of Bee Pollen Loads from Different Botanical Origin Molecules doi: 10.3390/molecules24213974 Authors: Sara Castiglioni Paola Astolfi Carla Conti Elga Monaci Mariassunta Stefano Patricia Carloni Bee pollen loads generally have a homogeneous and monospecific pollen content and assume a typical form and color, due to the typical bee foraging habits, thus having a typical composition...
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Molecules, Vol. 24, Pages 3973: A Generic Method for Fast and Sensitive Detection of Adeno-Associated Viruses Using Modified AAV Receptor Recombinant Proteins Molecules doi: 10.3390/molecules24213973 Authors: Mengtian Cui Yabin Lu Can Tang Ran Zhang Jing Wang Yang Si Shan Cheng Wei Ding Adeno-Associated Viruses (AAV) are widely used gene-therapy vectors for both clinical applications and laboratory investigations. The titering of different AAV preparations is important...
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Nanomaterials, Vol. 9, Pages 1558: Peptide-Mediated Immobilization on Magnetoferritin for Enzyme Recycling Nanomaterials doi: 10.3390/nano9111558 Authors: Zhang Dong Zhou Hu Li Wang Ferritin possess favorable properties because its exterior and interior surface can be applied to generate functional nanomaterials, which make them possible for enzyme immobilization and recycling. Here, we report the noncovalent immobilization of a genetically modified β-glucosidase...
Sat Nov 02, 2019 02:00
Nanomaterials, Vol. 9, Pages 1557: Fabrication of Interconnected Plasmonic Spherical Silver Nanoparticles with Enhanced Localized Surface Plasmon Resonance (LSPR) Peaks Using Quince Leaf Extract Solution Nanomaterials doi: 10.3390/nano9111557 Authors: Shujahadeen B. Aziz Govar Hussein M. A. Brza Sewara J. Mohammed R. T. Abdulwahid Salah Raza Saeed Abdollah Hassanzadeh Interconnected spherical metallic silver nanoparticles (Ag NPs) were synthesized in the current study...
Sat Nov 02, 2019 02:00
ncRNA, Vol. 5, Pages 51: Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation Non-Coding RNA doi: 10.3390/ncrna5040051 Authors: Ana S. Francisco-Garcia Eva M. Garrido-Martín Hitasha Rupani Laurie C. K. Lau Rocio T. Martinez-Nunez Peter H. Howarth Tilman Sanchez-Elsner MicroRNAs are known to regulate important pathways in asthma pathology including the...
Sat Nov 02, 2019 02:00
Nutrients, Vol. 11, Pages 2634: Berry-Enriched Diet in Salt-Sensitive Hypertensive Rats: Metabolic Fate of (Poly)Phenols and the Role of Gut Microbiota Nutrients doi: 10.3390/nu11112634 Authors: Gomes Oudot Macià Foito Carregosa Stewart Van de Wiele Berry Motilva Brenner dos Santos Diets rich in (poly)phenols are associated with a reduced reduction in the incidence of cardiovascular disorders. While the absorption and metabolism of (poly)phenols...
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Nutrients, Vol. 11, Pages 2636: Impact of Endurance and Resistance Training on Skeletal Muscle Glucose Metabolism in Older Adults Nutrients doi: 10.3390/nu11112636 Authors: Leslie A. Consitt Courtney Dudley Gunjan Saxena Aging is associated with insulin resistance and the development of type 2 diabetes. While this process is multifaceted, age-related changes to skeletal muscle are expected to contribute to impaired glucose metabolism. Some of these changes include sarcopenia, impaired...
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Nutrients, Vol. 11, Pages 2632: A Sustainable Wholesome Foodstuff; Health Effects and Potential Dietotherapy Applications of Yacon Nutrients doi: 10.3390/nu11112632 Authors: Mary R. Yan Robert Welch Elaine C. Rush Xuesong Xiang Xin Wang A sustainable food supply is an ever-growing public and planetary health concern influenced by food culture, food practices, and dietary patterns. Globally, the consumption of plant foods that offer physiological and biochemical benefits is...
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Nutrients, Vol. 11, Pages 2633: Food Addiction in Eating Disorders and Obesity: Analysis of Clusters and Implications for Treatment Nutrients doi: 10.3390/nu11112633 Authors: Susana Jiménez-Murcia Zaida Agüera Georgios Paslakis Lucero Munguia Roser Granero Jéssica Sánchez-González Isabel Sánchez Nadine Riesco Ashley N Gearhardt Carlos Dieguez Gilda Fazia Cristina Segura-García Isabel Baenas José M Menchón Fernando Fernández-Aranda Food addiction...
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Nutrients, Vol. 11, Pages 2631: Early Lifestyle Intervention for Obesity Prevention in Pediatric Survivors of Acute Lymphoblastic Leukemia Nutrients doi: 10.3390/nu11112631 Authors: Zhang Kelly Du Welch Santacruz Rhoades Kamins Dreyer Scheurer Patients with pediatric acute lymphoblastic leukemia (ALL) experience rapid weight gain during treatment and increases in weight are maintained throughout treatment and beyond. Without prompt interventions, altered...
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Nutrients, Vol. 11, Pages 2630: Obesity Affects β2 Adrenergic Regulation of the Inflammatory Profile and Phenotype of Circulating Monocytes from Exercised Animals Nutrients doi: 10.3390/nu11112630 Authors: Isabel Gálvez Leticia Martín-Cordero María Dolores Hinchado Alberto Álvarez-Barrientos Eduardo Ortega Anomalous immune/inflammatory responses in obesity take place along with alterations in the neuroendocrine responses and dysregulation in the immune/stress feedback mechanisms....
Sat Nov 02, 2019 02:00
Pathogens, Vol. 8, Pages 216: Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers Pathogens doi: 10.3390/pathogens8040216 Authors: López-Camacho Kim Abbink Larocca Huiskonen Barouch Reyes-Sandoval Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has spread to more than 70 countries worldwide since 2015. Despite active research, there are currently no licensed vaccines or therapeutics. We...
Sat Nov 02, 2019 02:00
Plants, Vol. 8, Pages 470: Two Wheat Cultivars with Contrasting Post-Embryonic Root Biomass Differ in Shoot Re-Growth after Defoliation: Implications for Breeding Grazing Resilient Forages Plants doi: 10.3390/plants8110470 Authors: Paez-Garcia Liao Blancaflor The ability of forages to quickly resume aboveground growth after grazing is a trait that enables farmers to better manage their livestock for maximum profitability. Leaf removal impairs root growth. As a consequence of...
Sat Nov 02, 2019 02:00
Religions, Vol. 10, Pages 609: Search for the Theological Grounds to Develop Inclusive Islamic Interpretations: Some Insights from Rationalistic Islamic Maturidite Theology Religions doi: 10.3390/rel10110609 Authors: Zhussipbek Satershinov Inclusive religious interpretations accept that a salvation beyond their teachings can be found. Whether Islam accepts inclusive religious interpretations or not, constitutes one of the most debated issues related to Islam in our days. In this...
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Religions, Vol. 10, Pages 608: ‘An Unstoppable Force for Good’?: How Neoliberal Governance Facilitated the Growth of Australian Suburban-Based Pentecostal Megachurches Religions doi: 10.3390/rel10110608 Authors: Mairead Shanahan Hillsong Church has received significant scholarly attention, which has observed the church’s rapid local and global growth. Several other Australian-based Pentecostal churches demonstrate a similar growth trajectory to Hillsong Church, namely: C3 Church,...
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Religions, Vol. 10, Pages 606: “Equal Rites”: Fragmenting and Healing Bodies in the Early Modern Bay of Kotor Religions doi: 10.3390/rel10110606 Authors: Milena Ulčar The aim of this paper is to examine the exchange of practices that developed when treating the bodies of ordinary laymen and those of saints. Body parts that had been obtained in unorthodox ways were used in private households in a manner strongly resembling the official methods of relic veneration. Conversely, the church...
Sat Nov 02, 2019 02:00
Religions, Vol. 10, Pages 607: A Sketch on Daisaku Ikeda as a Jamesian Psychologist of Religion Religions doi: 10.3390/rel10110607 Authors: Kim This essay attempts to determine whether Daisaku Ikeda can be seen as a Jamesian psychologist of religion. Concerning the development of this essay, it first focuses on a common concern that exists if we look at the work of William James and the Psychology of Religion in terms of how it exists as a distinct movement and how it is related to...
Sat Nov 02, 2019 02:00
Toxins, Vol. 11, Pages 640: Co-Occurrence and Combinatory Effects of Alternaria Mycotoxins and other Xenobiotics of Food Origin: Current Scenario and Future Perspectives Toxins doi: 10.3390/toxins11110640 Authors: Crudo Varga Aichinger Galaverna Marko Dall’Asta Dellafiora Mycotoxins are low-molecular weight compounds produced by diverse genera of molds that may contaminate food and feed threatening the health of humans and animals. Recent findings underline the...
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Toxins, Vol. 11, Pages 639: Cytotoxicity of Deoxynivalenol after Being Exposed to Gaseous Ozone Toxins doi: 10.3390/toxins11110639 Authors: Dongliang Ren Enjie Diao Hanxue Hou Peng Xie Ruifeng Mao Haizhou Dong Shiquan Qian In this study, deoxynivalenol (DON) in aqueous solution was exposed to gaseous ozone for periods ranging from 0 to 20 min. The degradation efficiency and cytotoxicity of DON were investigated after being treated by ozone. The results showed that DON...
Sat Nov 02, 2019 02:00
Vaccines, Vol. 7, Pages 175: Immunization Status against Measles of Health-Care Workers Operating at Three Sicilian University Hospitals: An Observational Study Vaccines doi: 10.3390/vaccines7040175 Authors: Claudio Costantino Caterina Ledda Cristina Genovese Eleonora Contrino Ermanno Vitale Carmelo Massimo Maida Raffaele Squeri Francesco Vitale Venerando Rapisarda Measles is a highly contagious vaccine-preventable disease (VPD) that also commonly affects health-care...
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Vaccines, Vol. 7, Pages 172: Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits Vaccines doi: 10.3390/vaccines7040172 Authors: Li Wang Tian Xia Tiantian Guo Yi Ru Yanping Jiang Wen Cui Han Zhou Xinyuan Qiao Lijie Tang Yigang Xu Yijing Li Rabbit hemorrhagic disease virus (RHDV) is the causative agent of rabbit hemorrhagic disease (RHD). RHD, characterized by hemorrhaging,...
Sat Nov 02, 2019 02:00
Vaccines, Vol. 7, Pages 173: Significant Interference with Porcine Epidemic Diarrhea Virus Pandemic and Classical Strain Replication in Small-Intestine Epithelial Cells Using an shRNA Expression Vector Vaccines doi: 10.3390/vaccines7040173 Authors: Da Shi Xiaobo Wang Hongyan Shi Jiyu Zhang Yuru Han Jianfei Chen Xin Zhang Jianbo Liu Jialin Zhang Zhaoyang Ji Zhaoyang Jing Li Feng Porcine epidemic diarrhea (PED) re-emerged in China in 2010 and is now widespread....
Sat Nov 02, 2019 02:00
Vaccines, Vol. 7, Pages 167: Succinate Coenzyme A Ligase Beta-Like Protein from Trichinella spiralis Suppresses the Immune Functions of Rat PBMCs in Vitro and Inhibits the Secretions of Interleukin-17 in Vivo Vaccines doi: 10.3390/vaccines7040167 Authors: Sun Li Naqvi Naqvi Chu Xu Song Li Yan : Succinate Coenzyme A ligase beta-like protein (SUCLA-β) is a subunit of Succinyl-coenzyme A synthetase, which is involved in substrate synergism, unusual...
Sat Nov 02, 2019 02:00
Vaccines, Vol. 7, Pages 174: Success and Limitation of Equine Influenza Vaccination: The First Incursion in a Decade of a Florida Clade 1 Equine Influenza Virus that Shakes Protection Despite High Vaccine Coverage Vaccines doi: 10.3390/vaccines7040174 Authors: Fougerolle Fortier Legrand Jourdan Marcillaud-Pitel Pronost Paillot Every year, several epizooties of equine influenza (EI) are reported worldwide. However, no EI case has been identified in France between...
Sat Nov 02, 2019 02:00
Viruses, Vol. 11, Pages 1018: Simultaneous Immunization with Multivalent Norovirus VLPs Induces Better Protective Immune Responses to Norovirus Than Sequential Immunization Viruses doi: 10.3390/v11111018 Authors: Maria Malm Timo Vesikari Vesna Blazevic Human noroviruses (NoVs) are a genetically diverse, constantly evolving group of viruses. Here, we studied the effect of NoV pre-existing immunity on the success of NoV vaccinations with genetically close and distant genotypes. A...
Sat Nov 02, 2019 02:00
Viruses, Vol. 11, Pages 1019: Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus Inhibitors Viruses doi: 10.3390/v11111019 Authors: Gao Tai Wang Li Jiang Debnath Du Chen Zika virus (ZIKV) infection during pregnancy leads to severe congenital Zika syndrome, which includes microcephaly and other neurological malformations. No therapeutic agents have, so far, been approved for the treatment of ZIKV infection in humans;...
Sat Nov 02, 2019 02:00
Water, Vol. 11, Pages 2301: Effects of Forest Thinning on the Long-Term Runoff Changes of Coniferous Forest Plantation Water doi: 10.3390/w11112301 Authors: Yang Choi Lim Forests and water are closely related to each other. Thus, forest management is crucial for the sustainable clean water supply. Forest thinning is one of the fundamental forest management practices, as it can change runoff by controlling the density of trees. In this study, the effect of forest thinning on...
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Water, Vol. 11, Pages 2300: Projections of Future Climate Change in Singapore Based on a Multi-Site Multivariate Downscaling Approach Water doi: 10.3390/w11112300 Authors: Xin Li Ke Zhang Vladan Babovic Estimates of the projected changes in precipitation and temperature have great significance for adaption planning in the context of climate change. To obtain the climate change information at regional or local scale, downscaling approaches are required to downscale the coarse global...
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Water, Vol. 11, Pages 2299: Impact of Soil Conservation and Eucalyptus on Hydrology and Soil Loss in the Ethiopian Highlands Water doi: 10.3390/w11112299 Authors: Demesew A. Mhiret Dessalegn C. Dagnew Tilashwork C. Alemie Christian D. Guzman Seifu A. Tilahun Benjamin F. Zaitchik Tammo S. Steenhuis The Ethiopian highlands suffer from severe land degradation, including erosion. In response, the Ethiopian government has implemented soil and water conservation practices...
Sat Nov 02, 2019 02:00
Water, Vol. 11, Pages 2298: The Use of Digital Terrain Models to Estimate the Pace of Filling the Pit of a Central European Granite Quarry with Water Water doi: 10.3390/w11112298 Authors: Bartosz Jawecki Szymon Szewrański Radosław Stodolak Zhaolong Wang This paper presents the results of an analysis of the pace of filling one of the deepest European granite quarries with water. A DTM (digital terrain model) based on data from LiDAR ALS (light detection and ranging airborne laser...
Sat Nov 02, 2019 02:00
Water, Vol. 11, Pages 2297: Mathematical Modeling of Ice Thrusting on the Shore of the Vistula Lagoon (Baltic Sea) and the Proposed Artificial Island Water doi: 10.3390/w11112297 Authors: Tomasz Kolerski Piotr Zima Michał Szydłowski Coastal lagoons are inland and shallow water bodies, separated from the ocean by a barrier. In cold regions, ice phenomena in shallow water coastal lagoons occur every winter season. Ice is predominantly formed on the surface due to density stratification...
Sat Nov 02, 2019 02:00
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