Toxicities associated with chemotherapy regimens containing a fluoropyrimidine: A real-life evaluation in France. Eur J Cancer. 2019 Nov 09;124:37-46 Authors: Barin-Le Guellec C, Lafay-Chebassier C, Ingrand I, Tournamille JF, Boudet A, Lanoue MC, Defossez G, Ingrand P, Perault-Pochat MC, Etienne-Grimaldi MC Abstract AIMS: Despite fluoropyrimidines (FPs) constituting the main component of the chemotherapy combination protocols in 50% of chemotherapies...
Wed Nov 13, 2019 19:37
Peak sinus pressures during sneezing in healthy controls and post-skull base surgery patients. Laryngoscope. 2019 Nov 12;: Authors: Wu Z, Craig JR, Maza G, Li C, Otto BA, Farag AA, Carrau RL, Zhao K Abstract OBJECTIVES/HYPOTHESIS: Patients are frequently advised to sneeze with an open mouth and avoid nose-blowing following an endoscopic endonasal approache (EEA) to the skull base, despite a lack of quantitative evidence. This study applies computational...
Wed Nov 13, 2019 19:37
Impact of primary tumor-specific growth rate on treatment failure for nonropharyngeal head and neck cancers. Laryngoscope. 2019 Nov 12;: Authors: Roldan CS, Chen JJ, Fareed MM, Hameed MY, Churilla TM, Lango MN, Galloway TJ Abstract OBJECTIVES: To investigate the prognostic impact of primary tumor-specific growth rate (TSGR) on treatment outcomes after definitive radiation therapy (RT) for nonoropharyngeal squamous cell carcinoma (non-OPSCC). ...
Wed Nov 13, 2019 19:37
Narrow band imaging in head and neck unknown primary carcinoma: A systematic review and meta-analysis. Laryngoscope. 2019 Nov 12;: Authors: Di Maio P, Iocca O, De Vergilo A, Giudice M, Pellini R, D'Ascanio L, Golusiński P, Ricci G, Spriano G Abstract OBJECTIVE: To estimate the diagnostic performance of Narrow Band Imaging (NBI) in patients with cervical metastasis from head and neck squamous cell carcinoma of unknown primary (SCCUP) origin. ...
Wed Nov 13, 2019 19:37
Endoscopic versus microscopic stapes surgery outcomes: A meta-analysis and systematic review. Laryngoscope. 2019 Nov 12;: Authors: Koukkoullis A, Tóth I, Gede N, Szakács Z, Hegyi P, Varga G, Pap I, Harmat K, Németh A, Szanyi I, Lujber L, Gerlinger I, Révész P Abstract OBJECTIVE: Compare intraoperative and postoperative outcomes of endoscopic and microscopic stapes surgery to provide objective evidence on whether the former is a better alternative than...
Wed Nov 13, 2019 19:37
Validity testing of a three-dimensionally printed endoscopic sinonasal surgery simulator. Laryngoscope. 2019 Nov 12;: Authors: Alwani MM, Svenstrup TJ, Bandali EH, Sharma D, Higgins TS, Wu AW, Shipchandler TZ, Illing EA, Ting JY Abstract OBJECTIVES/HYPOTHESIS: To assess the face, content, construct, and concurrent validity of the PHACON Sinonasal Surgery Simulator (SNSS). STUDY DESIGN: Prospective cohort study. METHODS: A total of 12...
Wed Nov 13, 2019 19:37
How I Do It: Midline posterior pharyngotomy for resection of postcricoid cancer. Laryngoscope. 2019 Nov 12;: Authors: Seok J, Ryu CH, Jung YS, Ryu J PMID: 31714603 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 19:37
What is the optimal timing for tracheostomy in intubated patients? Laryngoscope. 2019 Nov 12;: Authors: Panuganti BA, Weissbrod P, Damrose E PMID: 31714602 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 19:37
The natural history of vocal fold cysts. Laryngoscope. 2019 Nov 12;: Authors: Kirke DN, Sulica L Abstract OBJECTIVE: To determine the natural history of vocal fold cysts, by undertaking a retrospective analysis of data from a single clinical institute. METHODS: All patients diagnosed with vocal fold cysts were identified from January 2006 to June 2018. A total of 87 patients that elected not to have surgery or who had an interval of observation...
Wed Nov 13, 2019 19:37
A Therapeutic Education Program for patients that underwent at temporary tracheotomy and total laryngectomy: leading to improved the "Diagnostic, Therapeutic and Assistance Path". Acta Biomed. 2019 Nov 11;90(11-S):38-52 Authors: Spito A, Cavaliere B Abstract BACKGROUND AND AIM OF THE STUDY: Therapeutic education helps patients with a chronic disease to acquire and maintain the ability to live their life while handling their illness. Patients with temporary...
Wed Nov 13, 2019 19:37
Invasive Melanoma and Melanoma in Situ Treated With Modified Mohs Micrographic Surgery With En Face Permanent Sectioning: A 10-Year Retrospective Review. Dermatol Surg. 2019 Nov 06;: Authors: Heath M, Woody M, Leitenberger J, Latour E, Bar A Abstract BACKGROUND: Successful surgical treatment of cutaneous melanoma is dependent on margin control. OBJECTIVE: To determine efficacy of modified Mohs micrographic surgery (mMMS) with en face permanent...
Wed Nov 13, 2019 19:37
Reconstruction With Fibula Musculocutaneous Flap in a Patient With Extensive Maxillary Osteoradionecrosis. J Craniofac Surg. 2019 Nov 08;: Authors: Zhu F, Li X, Liu Z, He Y Abstract The authors reported a case of extensive maxillary osteoradionecrosis. The maxilla was resected and reconstructed with fibula musculocutaneous flap. It was the first reported that the osteoradionecrotic maxilla was reconstructed with free vascularized bone. The musculocutaneous...
Wed Nov 13, 2019 19:37
Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study. Int Clin Psychopharmacol. 2019 Oct 25;: Authors: Lee J, Jung HY, Lee SI, Choi JH, Kim SG Abstract The purpose of the present double-blind randomized placebo-controlled clinical study was to investigate the effects of Passionflower on polysomnographic sleep parameters in subjects with insomnia...
Wed Nov 13, 2019 19:37
An overview of radiological manifestations of acquired dental developmental disturbances in paediatric head and neck cancer survivors. Dentomaxillofac Radiol. 2019 Nov 12;:20190275 Authors: Hoogeveen RC, Hol MLF, Pieters BR, Balgobind BV, Berkhout EWER, Schoot RA, Smeele LE, Merks HJHM, Becking EAG Abstract OBJECTIVES: In paediatric cancer survivors treated with chemotherapy and radiotherapy therapy, late effects on dental development are quite common....
Wed Nov 13, 2019 19:37
Neuromuscular blockade management for intraoperative neural monitoring. Kaohsiung J Med Sci. 2019 Nov 12;: Authors: Lu IC, Wu SH, Wu CW Abstract This article reviews the literature on development of neuromuscular blockade management in thyroid surgery with intraoperative neural monitoring (IONM) in the past decade. Neuromuscular blockade management includes the choice of neuromuscular blocking agents (NMBAs) and reversal of neuromuscular blockade by...
Wed Nov 13, 2019 19:37
Preoperative vascular mapping for anterolateral thigh flap surgeries: A clinical trial of photoacoustic tomography imaging. Microsurgery. 2019 Nov 12;: Authors: Tsuge I, Saito S, Yamamoto G, Sekiguchi H, Yoshikawa A, Matsumoto Y, Suzuki S, Toi M Abstract BACKGROUND: Photoacoustic tomography (PAT) is a noninvasive vascular imaging modality that uses near-infrared pulse laser beams and ultrasound (US) to visualize vessels. We previously demonstrated the...
Wed Nov 13, 2019 19:37
Idiopathic spontaneous sublingual hematoma: a case report and literature review. Oral Maxillofac Surg. 2019 Nov 12;: Authors: Marin E, Fauconnier S, Bauters W, Huvenne W Abstract PURPOSE: Sublingual hematoma is a rare complication seen in bleeding disorders, trauma, dental procedures, and the use of anticoagulants. Only a few publications have described idiopathic spontaneous sublingual hematoma, and all of them suspected severe hypertension as etiology....
Wed Nov 13, 2019 19:37
Is pain part of a systemic syndrome in head and neck cancer? Support Care Cancer. 2019 Nov 12;: Authors: Bossi P, Ghiani M, Argenone A, Depenni R Abstract Head and neck cancers (HNC) represent 5% of all malignancies worldwide with about 180,000 cancer deaths per year. Patients with HNC are characterized by a systemic inflammatory state, generally associated with worse outcomes. Treatment-related toxicity is common among HNC patients and causes systemic...
Wed Nov 13, 2019 19:37
Protective effects of phenformin on zebrafish embryonic neurodevelopmental toxicity induced by X-ray radiation. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):4202-4210 Authors: Gan L, Guo M, Si J, Zhang J, Liu Z, Zhao J, Wang F, Yan J, Li H, Zhang H Abstract Radiotherapy (RT) is a common treatment for head and neck cancers, but central nervous system function can be impaired by clinical radiation doses. This experimental study evaluated the protective...
Wed Nov 13, 2019 19:37
Related Articles[Rhabditis axei found in urine routine examination: a case report]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019 May 08;31(5):565-566 Authors: Yu PX, Zhao Q, Meng ZM, Ji YJ Abstract Rhabditis axei is a free-living nematode, which can occasionally invade into humans through drinking and contacting wastewater. It is usually parasitic in the digestive and urinary systems, causing the disease of rhabditelliasis axei. This paper reports...
Wed Nov 13, 2019 19:37
Related ArticlesCorrelation Between the Sleep-Position Habits and the Affected Posterior Semicircular Canal in Patients with Benign Paroxysmal Positional Vertigo. Isr Med Assoc J. 2019 Nov;21(11):716-718 Authors: Yousovich R, Duvdevani SI, Lipschitz N, Wolf M, Migirov L, Yakirevitch A Abstract BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo. It is assumed that sleep is involved in the pathogenesis of BPPV,...
Wed Nov 13, 2019 19:37
Related ArticlesRadiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample. Allergy. 2019 Nov 11;: Authors: Hirsch AG, Nordberg C, Bandeen-Roche K, Tan BK, Schleimer RP, Kern RC, Sundaresan A, Pinto JM, Kennedy TL, Greene JS, Kuiper JR, Schwartz BS Abstract BACKGROUND: Chronic rhinosinusitis (CRS) epidemiology has been largely studied using symptom-based case definitions, without assessment of objective sinus findings....
Wed Nov 13, 2019 19:37
Related ArticlesDirect conversion of human fibroblasts into therapeutically active vascular wall-typical mesenchymal stem cells. Cell Mol Life Sci. 2019 Nov 11;: Authors: Steens J, Unger K, Klar L, Neureiter A, Wieber K, Hess J, Jakob HG, Klump H, Klein D Abstract Cell-based therapies using adult stem cells are promising options for the treatment of a number of diseases including autoimmune and cardiovascular disorders. Among these, vascular wall-derived...
Wed Nov 13, 2019 19:37
Related ArticlesEpigenetic Modifications in Head and Neck Cancer. Biochem Genet. 2019 Nov 11;: Authors: Gaździcka J, Gołąbek K, Strzelczyk JK, Ostrowska Z Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human malignancy in the world, with high mortality and poor prognosis for patients. Among the risk factors are tobacco and alcohol intake, human papilloma virus, and also genetic and epigenetic modifications. Many studies...
Wed Nov 13, 2019 19:37
Related ArticlesRisk factors of pharyngocutaneous fistula after total laryngectomy: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2019 Nov 11;: Authors: Wang M, Xun Y, Wang K, Lu L, Yu A, Guan B, Yu C Abstract OBJECTIVE: The purpose of this study was to systematically evaluate the risk factors of pharyngocutaneous fistula (PCF) after total laryngectomy. METHODS: We systematically searched Pubmed, Web of Science, Cochrane...
Wed Nov 13, 2019 19:37
Related Articles[Extranodal manifestation of classical Hodgkin lymphoma in the head and neck region]. HNO. 2019 Nov 11;: Authors: Völker HU, Becker E, Müller-Hermelink HK, Scheich M Abstract BACKGROUND: Extranodal lymphomas occurring in the head and neck region account for 12-15% of all malignant tumors of this locality. Classical Hodgkin lymphoma (cHL) is a rare subtype, representing around 1% of all lymphomas in Waldeyer's ring. Cases diagnosed in...
Wed Nov 13, 2019 19:37
Related Articles[Hospitalization of children after ENT surgery in Germany]. HNO. 2019 Nov 11;: Authors: Windfuhr JP, Sittel C, Deitmer T Abstract BACKGROUND: Morbidity following tonsil surgery is widely determined by pain, odynophagia, and bleeding. Detailed information about postoperative care in pediatric patients in Germany in the context of otolaryngologic interventions is currently lacking. MATERIALS AND METHODS: A questionnaire including...
Wed Nov 13, 2019 19:37
Related ArticlesIntravascular Papillary Endothelial Hyperplasia of the Vocal Cord: A Case Report and Review of the Literature. Am J Case Rep. 2019 Nov 12;20:1664-1668 Authors: Shim HK, Kim MR Abstract BACKGROUND Intravascular papillary endothelial hyperplasia (IPEH), is a vascular tumor characterized by the proliferation of endothelial cells with papillary formations. It is a rare benign disease; therefore, it is important to exclude malignant vascular...
Wed Nov 13, 2019 19:37
Related ArticlesChitosan oral patches inspired by mussel adhesion. J Control Release. 2019 Nov 08;: Authors: Ryu JH, Choi JS, Park E, Eom MR, Jo S, Lee MS, Kwon SK, Lee H Abstract Oral mucosal drug delivery systems have been developed to expedite the regeneration of oral mucosa, there are still many challenges related to residence time for drugs because the ceaseless changes of saliva, mouth movement, and involuntary swallowing prevent robust adhesion...
Wed Nov 13, 2019 19:37
Related ArticlesAuthor's response to the letter on the article: "Relation between adenoid size and otitis media with effusion". Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Nov 08;: Authors: Skoloudik L, Kalfert D, Valenta T, Chrobok V PMID: 31711952 [PubMed - as supplied by publisher]
Wed Nov 13, 2019 19:37
Related ArticlesInterarytenoid botulinum toxin A injection for the treatment of vocal process granuloma. J Laryngol Otol. 2019 Nov 12;:1-5 Authors: Hamdan AL, Khalifee E, Jaffal H, Ghanem A Abstract OBJECTIVES: To report on the efficacy and adverse effects of interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma. METHODS: A retrospective chart review was conducted of eight patients with vocal process granuloma...
Wed Nov 13, 2019 19:37
Related ArticlesThird or fourth branchial pouch sinus lesions: a case series and management algorithm. J Otolaryngol Head Neck Surg. 2019 Nov 11;48(1):61 Authors: Li Y, Lyu K, Wen Y, Xu Y, Wei F, Tang H, Chen S, Wang Z, Zhu X, Wen W, Lei W Abstract BACKGROUND: The purpose of this study was to develop an effective management algorithm for lesions of third or fourth branchial sinuses. STUDY DESIGN: Case series with chart review. METHODS:...
Wed Nov 13, 2019 19:37
Related ArticlesFollicular lymphoid hyperplasia of the posterior maxillary site presenting as uncommon entity: a case report and review of the literature. BMC Oral Health. 2019 Nov 11;19(1):243 Authors: Watanabe M, Enomoto A, Yoneyama Y, Kohno M, Hasegawa O, Kawase-Koga Y, Satomi T, Chikazu D Abstract BACKGROUND: Follicular lymphoid hyperplasia (FLH) is characterized by an increased number and size of lymphoid follicles. In some cases, the etiology of...
Wed Nov 13, 2019 19:37
Related ArticlesNovel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis. BMC Cancer. 2019 Nov 11;19(1):1083 Authors: Lin YW, Huang ST, Wu JC, Chu TH, Huang SC, Lee CC, Tai MH Abstract BACKGROUND: Hepatoma-derived growth factor (HDGF) participates in angiogenesis and represents a negative prognostic factor in oral cancer. The current study was designed to elucidate the regulatory mechanism between HDGF and vascular endothelial growth factor...
Wed Nov 13, 2019 19:37
Related ArticlesPHQ-9 and SNOT-22: Elucidating the Prevalence of Depression in Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2019 Nov 12;:194599819886852 Authors: Vandelaar LJ, Jiang ZY, Saini A, Yao WC, Luong AU, Citardi MJ Abstract OBJECTIVE: Chronic rhinosinusitis (CRS) has been associated with comorbid depression, yet the prevalence of depression among all patients with CRS is not well described. The Patient Health Questionnaire-9 (PHQ-9),...
Wed Nov 13, 2019 19:37
Related ArticlesTinnitus Treatment Using Noninvasive and Minimally Invasive Electric Stimulation: Experimental Design and Feasibility. Trends Hear. 2019 Jan-Dec;23:2331216518821449 Authors: Zeng FG, Richardson M, Tran P, Lin H, Djalilian H Abstract Noninvasive transcranial or minimally invasive transtympanic electric stimulation may offer a desirable treatment option for tinnitus because it can activate the deafferented auditory nerve fibers while...
Wed Nov 13, 2019 19:37
Related ArticlesNode metastases of epidermoid carcinoma in the neck with unknown primary tumor: in the current era does it still exist? Cir Cir. 2019;87(2):133-135 Authors: Gallegos-Hernández JF PMID: 30768075 [PubMed - indexed for MEDLINE]
Wed Nov 13, 2019 19:37
Related ArticlesCirculating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer. Br J Cancer. 2019 02;120(3):340-345 Authors: Varkaris A, Katsiampoura A, Davis JS, Shah N, Lam M, Frias RL, Ivan C, Shimizu M, Morris J, Menter D, Overman M, Tran H, Heymach J, Chun YS, Vauthey JN, Calin G, Kopetz S Abstract BACKGROUND: Metastatic colorectal cancer (mCRC) is a highly heterogeneous disease from a clinical,...
Wed Nov 13, 2019 19:37
Related ArticlesThe Human Cochlear Aqueduct and Accessory Canals: a Micro-CT Analysis Using a 3D Reconstruction Paradigm. Otol Neurotol. 2018 07;39(6):e429-e435 Authors: Atturo F, Schart-Morén N, Larsson S, Rask-Andersen H, Li H Abstract OBJECTIVE: We sought to study the anatomic variations of the cochlear aqueduct and its accessory canals in human temporal bones using micro-CT and a 3D reconstruction paradigm. More knowledge about the anatomic variations...
Wed Nov 13, 2019 19:37
Related ArticlesPredicting Performance and Non-Use in Prelingually Deaf and Late-Implanted Cochlear Implant Users. Otol Neurotol. 2018 07;39(6):e436-e442 Authors: Lammers MJW, Versnel H, Topsakal V, van Zanten GA, Grolman W Abstract OBJECTIVE: To analyze postoperative hearing performance and independent predictors of speech perception and to assess cochlear implant nonuse in adults with prelingual deafness who received an implant during adulthood. ...
Wed Nov 13, 2019 19:37
Related ArticlesBlocking Tumor Necrosis Factor-Alpha Expression Prevents Blast-Induced Excitatory/Inhibitory Synaptic Imbalance and Parvalbumin-Positive Interneuron Loss in the Hippocampus. J Neurotrauma. 2018 10 01;35(19):2306-2316 Authors: Wang W, Zinsmaier AK, Firestone E, Lin R, Yatskievych TA, Yang S, Zhang J, Bao S Abstract Traumatic brain injury (TBI) is a major cause of neurological disorder and death in civilian and military populations. It...
Wed Nov 13, 2019 19:37
Related ArticlesSevere late dysphagia after multimodal treatment of stage III/IV laryngeal and hypopharyngeal cancer. Jpn J Clin Oncol. 2019 Nov 11;: Authors: Huh G, Ahn SH, Suk JG, Lee MH, Kim WS, Kwon SK, Ock CY, Keam B, Heo DS, Kim JH, Wu HG Abstract BACKGROUND: Long-term side effects after radiotherapy for organ preservation 'could deteriorate' the laryngeal function. This study intended to identify the incidence of severe late dysphagia following...
Tue Nov 12, 2019 16:21
Related ArticlesAssociation between hepatitis C and B viruses and head and neck squamous cell carcinoma. J Clin Virol. 2019 Nov 04;121:104209 Authors: Donà S, Borsetto D, Fussey J, Biscaro V, Vian E, Spinato G, Menegaldo A, Da Mosto MC, Rigoli R, Polesel J, Boscolo-Rizzo P Abstract BACKGROUND: Hepatitis B and C viruses are known to be carcinogenic and have been associated with the development of non-Hodgkin's lymphoma as well as hepatocellular carcinoma....
Tue Nov 12, 2019 16:21
Related ArticlesPrognostic importance of radiologic extranodal extension in HPV-positive oropharyngeal carcinoma and its potential role in refining TNM-8 cN-classification. Radiother Oncol. 2019 Nov 08;144:13-22 Authors: Huang SH, O'Sullivan B, Su J, Bartlett E, Kim J, Waldron JN, Ringash J, de Almeida JR, Bratman S, Hansen A, Bayley A, Cho J, Giuliani M, Hope A, Hosni A, Spreafico A, Siu L, Chepeha D, Tong L, Xu W, Yu E Abstract PURPOSE: This study...
Tue Nov 12, 2019 16:21
Related ArticlesSuppression tuning of spontaneous otoacoustic emissions in the barn owl (Tyto alba). Hear Res. 2019 Nov 01;385:107835 Authors: Engler S, Köppl C, Manley GA, de Kleine E, van Dijk P Abstract Spontaneous otoacoustic emissions (SOAEs) have been observed in a variety of different vertebrates, including humans and barn owls (Tyto alba). The underlying mechanisms producing the SOAEs and the meaning of their characteristics regarding the frequency...
Tue Nov 12, 2019 16:21
Related ArticlesThe Use of Optical Coherence Tomography and Convolutional Neural Networks to Distinguish Normal and Abnormal Oral Mucosa. J Biophotonics. 2019 Nov 11;: Authors: Heidari AE, Pham TT, Ifegwu I, Burwell R, Armstrong WB, Tjoson T, Whyte S, Giorgioni C, Wang B, Wong BJF, Chen Z Abstract Incomplete surgical resection of head and neck squamous cell carcinoma (HNSCC) is the most common cause of local HNSCC recurrence. Currently, surgeons rely...
Tue Nov 12, 2019 16:21
Related ArticlesChronic cerebrospinal venous insufficiency and menière's disease: Interventional versus medical therapy. Laryngoscope. 2019 Nov 11;: Authors: Attanasio G, Califano L, Bruno A, Giugliano V, Ralli M, Martellucci S, Milella C, de Vincentiis M, Russo FY, Greco A Abstract OBJECTIVES/HYPOTHESIS: To evaluate the incidence of chronic cerebrospinal venous insufficiency in Menière's disease patients and the effect of bilateral percutaneous transluminal...
Tue Nov 12, 2019 16:21
Related ArticlesLong-term audiologic outcomes after cochlear implantation for single-sided deafness. Laryngoscope. 2019 Nov 11;: Authors: Sullivan CB, Al-Qurayshi Z, Zhu V, Liu A, Dunn C, Gantz BJ, Hansen MR Abstract OBJECTIVES: To evaluate the long-term audiometric outcomes, sound localization abilities, binaural benefits, and tinnitus assessment of subjects with cochlear implant (CI) after a diagnosis of unilateral severe-to-profound hearing loss....
Tue Nov 12, 2019 16:21
Related ArticlesOptogenetically transduced human ES cell-derived neural progenitors and their neuronal progenies: Phenotypic characterization and responses to optical stimulation. PLoS One. 2019;14(11):e0224846 Authors: Ryu J, Vincent PFY, Ziogas NK, Xu L, Sadeghpour S, Curtin J, Alexandris AS, Stewart N, Sima R, du Lac S, Glowatzki E, Koliatsos VE Abstract Optogenetically engineered human neural progenitors (hNPs) are viewed as promising tools in regenerative...
Tue Nov 12, 2019 16:21
Related ArticlesGenetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches. PLoS One. 2019;14(11):e0224858 Authors: Ali HA, Lomholt AF, Hamidreza Mahmoudpour S, Hermanrud T, Bygum A, von Buchwald C, Jakobsen MA, Rasmussen ER Abstract Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II which causes vasoconstriction. ACE inhibitors reduce...
Tue Nov 12, 2019 16:21
Related ArticlesFissured tongue. Cleve Clin J Med. 2019 Nov;86(11):714 Authors: Bakshi SS PMID: 31710590 [PubMed - in process]
Tue Nov 12, 2019 16:21
Related ArticlesGalectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. J Clin Invest. 2019 Nov 11;: Authors: Nambiar DK, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, Wang Z, Rangan VS, Jiang D, von Eyben R, Liang R, Agarwal S, Colevas AD, Korman A, Allen CT, Uppaluri R, Koong AC, Giaccia A, Le QT Abstract Immune checkpoint inhibitors (ICIs), although promising, have variable benefit in head and neck cancer...
Tue Nov 12, 2019 16:21
Related ArticlesCancer immunotherapy needs to learn how to stick to its guns. J Clin Invest. 2019 Nov 11;: Authors: Chakraborty A, Dimitroff CJ Abstract Cancer immunotherapy and its budding effectiveness at improving patient outcomes has revitalized our hope to fight cancer in a logical and safe manner. Immunotherapeutic approaches to reengage the immune system have largely focused on reversing immune checkpoint inhibitor pathways, which suppress the...
Tue Nov 12, 2019 16:21
Related ArticlesThe bone conduction implant - a review and 1-year follow-up. Int J Audiol. 2019 Dec;58(12):945-955 Authors: Håkansson B, Reinfeldt S, Persson AC, Jansson KF, Rigato C, Hultcrantz M, Eeg-Olofsson M Abstract Objective: The objective of this study is to evaluate its safety and effectiveness of the bone conduction implant (BCI) having an implanted transducer and to review similar bone conduction devices.Design: This is a consecutive prospective...
Tue Nov 12, 2019 16:21
Related ArticlesPatterns of protein expression in human head and neck cancer cell lines differ after proton vs photon radiotherapy. Head Neck. 2019 Nov 11;: Authors: Wang L, Yang L, Han S, Zhu J, Li Y, Wang Z, Fan YH, Lin E, Zhang R, Sahoo N, Li Y, Zhang X, Wang X, Li T, Zhu XR, Zhu H, Heymach JV, Myers JN, Frank SJ Abstract BACKGROUND: Proton radiotherapy (PRT) may be a less toxic alternative to photon radiotherapy (XRT) for patients with head and neck...
Tue Nov 12, 2019 16:21
Related ArticlesLong noncoding RNA KCNQ1OT1 promotes proliferation, migration, and invasion in maxillary sinus squamous cell carcinoma by regulating miR-204/EphA7 axis. J Cell Biochem. 2019 Nov 10;: Authors: Sun Y, Xu C, Wu Q, Zhang L, Wang P Abstract Long noncoding RNAs have been demonstrated to contribute to the development and progression of various cancers. However, the underlying regulatory mechanisms of KCNQ1OT1 in tumorigenesis of maxillary sinus...
Tue Nov 12, 2019 13:19
Related ArticlesSTAT1 inhibits T cell exhaustion and myeloid derived suppressor cell accumulation to promote anti-tumor immune responses in head and neck squamous cell carcinoma. Int J Cancer. 2019 Nov 10;: Authors: Ryan N, Anderson K, Volpedo G, Hamza O, Varikuti S, Satoskar AR, Oghumu S Abstract Cancers of the oral cavity remain the sixth most diagnosed cancer worldwide, with high rates of recurrence and mortality. We determined the role of STAT1 during...
Tue Nov 12, 2019 13:19
Related ArticlesEndoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: a systematic review. Neurosurg Rev. 2019 Nov 10;: Authors: Purohit A, Jha R, Khalafallah AM, Price C, Rowan NR, Mukherjee D Abstract Despite the increasing utility of the endoscopic endonasal approach (EEA) for management of anterior skull base (ASB) pathologies, the optimal treatment strategy for olfactory groove meningiomas (OGM) remains...
Tue Nov 12, 2019 13:19
Related ArticlesA Review of Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study-Part 4 (Biomarkers). Front Oncol. 2019;9:1128 Authors: Broglie MA, Dulguerov P, Henke G, Siano M, Putora PM, Simon C, Zwahlen D, Huber GF, Ballerini G, Beffa L, Giger R, Rothschild S, Negri SV, Elicin O Abstract Background: The Head and Neck Cancer Working Group of Swiss Group for Clinical...
Tue Nov 12, 2019 13:19
Related ArticlesA Review of Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study-Part 3 (Medical Oncology). Front Oncol. 2019;9:1127 Authors: Siano M, Dulguerov P, Broglie MA, Henke G, Putora PM, Simon C, Zwahlen D, Huber GF, Ballerini G, Beffa L, Giger R, Rothschild S, Negri SV, Elicin O Abstract Background: The Head and Neck Cancer Working Group of Swiss Group for Clinical...
Tue Nov 12, 2019 13:19
Related ArticlesA Review of Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study-Part 2 (Radiation Oncology). Front Oncol. 2019;9:1126 Authors: Elicin O, Putora PM, Siano M, Broglie MA, Simon C, Zwahlen D, Huber GF, Ballerini G, Beffa L, Giger R, Rothschild S, Negri SV, Dulguerov P, Henke G Abstract Background: The Head and Neck Cancer Working Group of Swiss Group for...
Tue Nov 12, 2019 13:19
Related ArticlesA Review of Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study-Part 1 (Head and Neck Surgery). Front Oncol. 2019;9:1125 Authors: Dulguerov P, Broglie MA, Henke G, Siano M, Putora PM, Simon C, Zwahlen D, Huber GF, Ballerini G, Beffa L, Giger R, Rothschild S, Negri SV, Elicin O Abstract Background: The Head and Neck Cancer Working Group of Swiss Group...
Tue Nov 12, 2019 13:19
Related ArticlesPrognostic Value of Programmed Cell Death Ligand-1 Expression in Nasopharyngeal Carcinoma: A Meta-Analysis of 1,315 Patients. Front Oncol. 2019;9:1111 Authors: Liu X, Shan C, Song Y, Du J Abstract Background: The prognostic value of programmed cell death ligand-1 (PD-L1) in patients with nasopharyngeal carcinoma (NPC) remains controversial. Therefore, we conducted this meta-analysis to understand the role of PD-L1 in NPC. Method: We searched...
Tue Nov 12, 2019 13:19
Related ArticlesStrong dose response after immunotherapy with PQ grass using conjunctival provocation testing. World Allergy Organ J. 2019 Nov;12(11):100075 Authors: Zielen S, Kuna P, Aberer W, Lassmann S, Pfaar O, Klimek L, Wade A, Kluehr K, Raab J, Wessiepe D, Lee D, Kramer MF, Gunawardena K, Higenbottam T, Heath MD, Skinner MA, de Kam PJ Abstract Background: Pollinex Quattro Grass (PQ Grass) is an effective, well-tolerated, short pre-seasonal subcutaneous...
Tue Nov 12, 2019 13:19
Related ArticlesThe Common Costimulatory and Coinhibitory Signaling Molecules in Head and Neck Squamous Cell Carcinoma. Front Immunol. 2019;10:2457 Authors: Liao P, Wang H, Tang YL, Tang YJ, Liang XH Abstract Head and neck squamous cell carcinomas (HNSCCs) are closely linked with immunosuppression, accompanied by complex immune cell functional activities. The abnormal competition between costimulatory and coinhibitory signal molecules plays an important...
Tue Nov 12, 2019 13:19
Related ArticlesThe Therapeutic Effect of 1,8-Cineol on Pathogenic Bacteria Species Present in Chronic Rhinosinusitis. Front Microbiol. 2019;10:2325 Authors: Schürmann M, Oppel F, Gottschalk M, Büker B, Jantos CA, Knabbe C, Hütten A, Kaltschmidt B, Kaltschmidt C, Sudhoff H Abstract Chronic rhinosinusitis (CRS) is marked by an inflamed mucosa of sinuses and is accompanied by a significantly reduced quality of live. Since no guidelines for the treatment...
Tue Nov 12, 2019 13:19
Related ArticlesAn Analysis of Clinical Characteristics of Rare Bilateral Cerebral Peduncular Infarction. Front Neurol. 2019;10:1107 Authors: Chen H, Hu Q, Raza HK, Singh S, Rai P, Zhu J, Cui G, Ye X, Xu C, Jing J, Liu Y Abstract Objective: To investigate the anatomical characteristics, clinical manifestations, and imaging features of bilateral cerebral peduncular infarction. Methods: A retrospective analysis was performed on 11 patients diagnosed with...
Tue Nov 12, 2019 13:19
Related ArticlesImmune Checkpoint Inhibitor Toxicity in Head and Neck Cancer: From Identification to Management. Front Pharmacol. 2019;10:1254 Authors: Wang H, Mustafa A, Liu S, Liu J, Lv D, Yang H, Zou J Abstract Benefiting from the continuously clarifying underlying biology of immune checkpoints and ligand-receptor interactions, the emergence of new anticancer treatment strategy, immunotherapy has shown substantial benefits on several liquid and solid...
Tue Nov 12, 2019 13:19
Related ArticlesAlteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris. Front Cell Neurosci. 2019;13:481 Authors: Kinoshita M, Fujimoto C, Iwasaki S, Kashio A, Kikkawa YS, Kondo K, Okano H, Yamasoba T Abstract The mechanism underlying hair cell (HC) regeneration in the mammalian inner ear is still under debate. Understanding what molecules regulate the HC...
Tue Nov 12, 2019 13:19
Related ArticlesPanitumumab-induced pulmonary toxicity. Curr Oncol. 2019 Oct;26(5):e700-e702 Authors: Arora R, Kisiel M, MacColl C Abstract Mutations in EGFR have been implicated in the pathogenesis of various types of cancer, and therefore antibody therapy directed against the epidermal growth factor receptor (egfr) is increasingly being used in the management of various cancers. Currently, anti-egfr antibodies are used mainly in the management of cancers...
Tue Nov 12, 2019 13:19
Related ArticlesDiagnosis and pathologic characteristics of medullary thyroid carcinoma-review of current guidelines. Curr Oncol. 2019 Oct;26(5):338-344 Authors: Thomas CM, Asa SL, Ezzat S, Sawka AM, Goldstein D Abstract Background: Medullary thyroid carcinoma (mtc) is a rare malignancy of the thyroid gland, and raising awareness of the recommended diagnostic workup and pathologic characteristics of this malignancy is therefore important. Methods:...
Tue Nov 12, 2019 13:19
Related ArticlesMelanoma nodal management in Ontario the year after the 2012 American Society of Clinical Oncology and Society of Surgical Oncology guideline. Curr Oncol. 2019 Oct;26(5):330-337 Authors: Latosinsky S, Allen B, Shariff SZ Abstract Background: In 2012 in the United States, the American Society of Clinical Oncology and the Society of Surgical Oncology (asco/sso) published a joint guideline about indications for sentinel lymph node biopsy...
Tue Nov 12, 2019 13:19
Related ArticlesDoes the frequency of routine follow-up after curative treatment for head-and-neck cancer affect survival? Curr Oncol. 2019 Oct;26(5):295-306 Authors: Hall SF, Owen T, Griffiths RJ, Brennan K Abstract Background: Routine follow-up is a cornerstone of oncology practice, but evidence to support most aspects of follow-up is lacking. Our objective was to investigate the relationship between frequency of routine follow-up and survival. ...
Tue Nov 12, 2019 13:19
Related ArticlesThe endoscopic anatomy of the cochlear hook region and fustis: surgical implications. Acta Otorhinolaryngol Ital. 2019 Oct;39(5):353-357 Authors: Anschuetz L, Alicandri-Ciufelli M, Wimmer W, Bonali M, Caversaccio M, Presutti L PMID: 31708582 [PubMed - in process]
Tue Nov 12, 2019 13:19
Related ArticlesHuman papillomavirus as a driver of head and neck cancers. Br J Cancer. 2019 Nov 11;: Authors: Sabatini ME, Chiocca S Abstract The human papillomavirus (HPV) family includes more than 170 different types of virus that infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical cancer, but in recent years, a clear role for this virus in other malignancies is also emerging. Indeed, HPV plays a pathogenic...
Tue Nov 12, 2019 13:19
Related ArticlesEpidemiological study of oral allergy syndrome in birch pollen dispersal-free regions. Allergol Int. 2019 Nov 07;: Authors: Osawa Y, Ito Y, Takahashi N, Sugimoto C, Kohno Y, Mori S, Morikawa T, Kato Y, Okamoto M, Kanno M, Takabayashi T, Fujieda S Abstract BACKGROUND: Oral allergy syndrome (OAS) is an immediate allergy caused by a cross-reaction of highly homologous common antigens (pan-allergens) contained in fruits/vegetables and pollen....
Tue Nov 12, 2019 13:19
Related ArticlesCharacteristics of upright versus supine reflux pattern in patients with laryngopharyngeal reflux. Braz J Otorhinolaryngol. 2019 Sep 18;: Authors: Mesallam TA, Baqays AA Abstract INTRODUCTION: Many laryngeal-related problems have been attributed to laryngopharyngeal reflux including dysphonia, frequent throat clearing, chronic cough, and globus sensation. However, there is still controversy regarding diagnosis and clinical presentation...
Tue Nov 12, 2019 13:19
Related ArticlesValidation of Acoustic Voice Quality Index Version 3.01 and Acoustic Breathiness Index in Korean Population. J Voice. 2019 Nov 07;: Authors: Kim GH, von Latoszek BB, Lee YW Abstract OBJECTIVES: This study aimed to verify the Acoustic Voice Quality Index (AVQI) version 3.01 and the Acoustic Breathiness Index (ABI) as tools for acoustic analyses in the Korean language. METHODS: Concatenated voice samples of sustained vowels (SV)...
Tue Nov 12, 2019 13:19
Related ArticlesRadiation induced hypothyroidism - Why is early intervention necessary? Oral Oncol. 2019 Nov 07;:104442 Authors: Aggarwal K, Thakur S, Shetty SS, Rao V PMID: 31708265 [PubMed - as supplied by publisher]
Tue Nov 12, 2019 13:19
Related ArticlesIn-home auditory training using audiovisual stimuli on a tablet computer: Feasibility and preliminary results. Auris Nasus Larynx. 2019 Nov 07;: Authors: Sato T, Yabushita T, Sakamoto S, Katori Y, Kawase T Abstract OBJECTIVE: To examine the feasibility and possible effects of in-home auditory training using audiovisual speech stimuli on a tablet computer for patients with hearing loss using a hearing aid (HA) or a cochlear implant (CI)....
Tue Nov 12, 2019 13:19
Related ArticlesHuman immunodeficiency disease in new diagnoses of head and neck squamous cell cancer: are we testing? J Laryngol Otol. 2019 Nov 11;:1-3 Authors: McNamara KJ, Fernandez C, Saunders TFC, Ahsan F Abstract BACKGROUND: Human immunodeficiency virus infected patients have a three-fold increased risk of head and neck squamous cell carcinoma. The British HIV Association recommends human immunodeficiency virus testing in all new diagnoses of head...
Tue Nov 12, 2019 13:19
Related ArticlesAssociations between pressure pain threshold in the neck and postural control in patients with dizziness or neck pain - a cross-sectional study. BMC Musculoskelet Disord. 2019 Nov 10;20(1):528 Authors: Knapstad MK, Goplen FK, Ask T, Skouen JS, Nordahl SHG Abstract BACKGROUND: It is theorized that neck pain may cause reduced postural control due to the known physiological connection between the receptors in the cervical spine and the vestibular...
Tue Nov 12, 2019 13:19
Related ArticlesTranscanal endoscopic ear surgery for traumatic ossicular injury. Acta Otolaryngol. 2019 Nov 09;:1-5 Authors: Kim MS, Chung J, Kang JY, Choi JW Abstract Background: Transcanal endoscopic ear surgery (TEES) for traumatic ossicular injuries (TOI) is not well studied.Objectives: To analyze the treatment outcomes of TEES for TOI.Material and methods: Retrospective case review of fifteen patients (15 ears) with TOI was performed. The patients...
Tue Nov 12, 2019 13:19
Related ArticlesPresentation and Management of Killian Jamieson Diverticulum: A Comprehensive Literature Review. Ann Otol Rhinol Laryngol. 2019 Nov 09;:3489419887403 Authors: Haddad N, Agarwal P, Levi JN, Tracy JC, Tracy LF Abstract OBJECTIVE: To examine the clinical presentation, diagnostic evaluation, and management of Killian-Jamieson diverticula (KJD) through literature review. METHODS: A comprehensive literature review was conducted through...
Tue Nov 12, 2019 13:19
Related ArticlesFunction, Applicability, and Properties of a Novel Flexible Total Ossicular Replacement Prosthesis With a Silicone Coated Ball and Socket Joint. Otol Neurotol. 2018 07;39(6):739-747 Authors: Stoppe T, Bornitz M, Lasurashvili N, Sauer K, Zahnert T, Zaoui K, Beleites T Abstract HYPOTHESIS: A total ossicular replacement prosthesis (TORP) with a silicone coated ball and socket joint (BSJ) is able to compensate pressure changes and therefore...
Tue Nov 12, 2019 13:19
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