• Allergy
• Simultaneous up‐dosing of bee and vespid venom immunotherapy is safe

  Allergy

  Tue Oct 08, 2019 11:44
• Dupilumab is very effective in a large cohort of difficult‐to‐treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry

  Abstract Introduction Dupilumab has recently been approved for the treatment of moderate to severe atopic dermatitis (AD) in adults. Daily practice data on dupilumab treatment are scarce. Objective To study the effect of 16 weeks treatment with dupilumab on clinical response and serum biomarkers in adult patients with moderate‐severe AD in daily practice. Methods Data were extracted from the BioDay registry, a prospective multicen

  Allergy

  Tue Oct 08, 2019 08:48
• Recent developments and highlights in food allergy

  Abstract The achievement of long lasting, safe treatments for food allergy is dependent on the understanding of the immunological basis of food allergy. Accurate diagnosis is essential for management. In recent years, data from oral food challenges have revealed that routine allergy testing is poor at predicting clinical allergy for tree nuts, almonds in particular. More advanced antigen‐based tests including component resolved diagnostics and e

  Allergy

  Tue Oct 08, 2019 07:42
• Allergy
• Correction to: Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

  Following publication of the original article [1], the authors reported that one of the collaborators’ names was spelled incorrectly. In this Correction the incorrect and correct author name are shown. In the ...

  Allergy

  Tue Oct 08, 2019 17:00
• Correction to: MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence

  Following publication of the original article [1], the authors reported that one of the collaborators’ names was spelled incorrectly. In this Correction the incorrect and correct author name are shown. In the ...

  Allergy

  Tue Oct 08, 2019 17:00
• Clinically relevant effect of rupatadine 20 mg and 10 mg in seasonal allergic rhinitis: a pooled responder analysis

  Different clinical trials showed the superior efficacy of rupatadine compared to placebo at improving seasonal allergic rhinitis (SAR) symptoms, but no study has assessed if the response promoted is clinically...

  Allergy

  Tue Oct 08, 2019 17:00
• Annals of Allergy, Asthma & Immunology
• Clinical response to omalizumab in patients with hereditary alpha tryptasemia

  Hereditary alpha tryptasemia (HαT) is a genetic trait that results from increased TPSAB1 copy number encoding alpha-tryptase and is characterized by elevated basal serum tryptase (BST) levels of ≥8ng/mL with variably expressed clinical symptoms (1). In addition to multisystem complaints involving gastrointestinal, connective tissue, and neurologic systems, many individuals with HαT report symptoms associated with mast cell activation such as chro

  Annals of Allergy, Asthma & Immunology

  Tue Oct 08, 2019 17:00
• Cardiopulmonary Exercise Testing for Pediatric Exercise Induced Dyspnea Especially in Patients who Failed Asthma Treatment

  Exercise-induced bronchospasm (EIB) is the most common suspected diagnosis for exercise induced dyspnea (EID) in pediatric patients with or without asthma.1,2 Previous studies show that EIB is present in just 8%-19% of otherwise healthy children with EID 1,2,3. In fact, a majority of these patients have one or more problems other than EIB limiting exercise. Cardiopulmonary Exercise Testing (CPET) can identify clinical entities that mimic EIB. Mul

  Annals of Allergy, Asthma & Immunology

  Tue Oct 08, 2019 17:00
• Poor control of asthma symptoms with interleukin-5 inhibitors in four patients with aspirin-exacerbated respiratory disease

  Aspirin-exacerbated respiratory disease (AERD) is a condition of the respiratory tract characterized by rhinosinusitis, asthma, eosinophilia, and respiratory reactions to nonsteroidal anti-inflammatory drugs. The pathophysiology of AERD involves a baseline dysregulation of arachidonic acid metabolism leading to the overproduction of leukotrienes.1 Leukotrienes are inducers of bronchoconstriction and also attract eosinophils into the airways.2 The

  Annals of Allergy, Asthma & Immunology

  Tue Oct 08, 2019 17:00
• Clinical & Experimental Allergy
• The time course of anaphylaxis manifestations in children is diverse and unpredictable

  Abstract The most current clinical definition of anaphylaxis is that proposed by Sampson et al. and different scoring systems have been proposed to assess its severity [1,2]. Anaphylaxis symptoms range from mild, self‐limiting local reactions to life‐threatening anaphylaxis. All anaphylaxis guidelines emphasize early recognition and the need for prompt intramuscular adrenaline injection as the first‐line treatment [3]. However, adrenaline for a

  Clinical & Experimental Allergy

  Tue Oct 08, 2019 02:38
• Current Allergy and Asthma Reports
• Comparative Review of Asthma in Farmers and Horses

  Abstract Purpose of Review Farmers are routinely exposed to organic dusts and aeroallergens that can have adverse respiratory health effects including asthma. Horses are farm-reared large animals with similar exposures and can develop equine asthma syndrome (EAS). This review aims to compare the etiology, pathophysiology, and immunology of asthma in horses compared to farmers and

  Current Allergy and Asthma Reports

  Wed Oct 09, 2019 17:00