Toxins, Vol. 11, Pages 681: Biosecurity Threat Posed by Botulinum Toxin Toxins doi: 10.3390/toxins11120681 Authors: Cenciarelli Riley Baka The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized...
Toxins, Vol. 11, Pages 682: Qualitative Assay to Detect Dopamine Release by Ligand Action on Nicotinic Acetylcholine Receptors Toxins doi: 10.3390/toxins11120682 Authors: Marquart Turner McDougal A pheochromocytoma of the rat adrenal medulla derived (a.k.a. PC12) cell-based assay for dopamine measurement by luminescence detection was customized for the qualitative evaluation of agonists and antagonists of nicotinic acetylcholine receptors (nAChRs). The assay mechanism begins...
Toxins, Vol. 11, Pages 679: Crotoxin Conjugated to SBA-15 Nanostructured Mesoporous Silica Induces Long-Last Analgesic Effect in the Neuropathic Pain Model in Mice Toxins doi: 10.3390/toxins11120679 Authors: Brazil Sant’Anna Souza Ribeiro Lopes Faggionato Kimura Carolina Giardini Augusto Sant’Anna Picolo Neuropathic pain is a disease caused by structural and functional plasticity in central and peripheral sensory pathways that produce alterations in nociceptive processing....
Toxins, Vol. 11, Pages 680: Newly Discovered Action of HpTx3 from Venom of Heteropoda venatoria on Nav1.7 and Its Pharmacological Implications in Analgesia Toxins doi: 10.3390/toxins11120680 Authors: Wu Wang Chen Xu Zhang Wang It has been reported that Heteropodatoxin3 (HpTx3), a peptidic neurotoxin purified from the venom of the spider species Heteropoda venatoria, could inhibit Kv4.2 channels. Our present study newly found that HpTx3 also has potent and selective...
Toxins, Vol. 11, Pages 678: Repeated Oral Administration of a KDEL-tagged Recombinant Cholera Toxin B Subunit Effectively Mitigates DSS Colitis Despite a Robust Immunogenic Response Toxins doi: 10.3390/toxins11120678 Authors: Royal Reeves Matoba Cholera toxin B subunit (CTB), a non-toxic homopentameric component of Vibrio cholerae holotoxin, is an oral cholera vaccine antigen that induces an anti-toxin antibody response. Recently, we demonstrated that a recombinant CTB variant...
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Urban Science, Vol. 3, Pages 105: The Character of Urban Japan: Overview of Osaka-Kobe’s Cityscapes Urban Science doi: 10.3390/urbansci3040105 Authors: Perez Araldi Fusco Fuse : The Japanese city presents a certain number of peculiarities in the organization of its physical space (weak zoning regulations, fast piecemeal destruction/reconstruction of buildings and blocks, high compacity, incremental reorganization). Compared to countries where urban fabrics are more perennial...
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Vaccines, Vol. 7, Pages 190: A vaccinology Approach to the Identification and Characterization of Dermanyssus Gallinae Candidate Protective Antigens for the Control of Poultry Red Mite Infestations Vaccines doi: 10.3390/vaccines7040190 Authors: Lima-Barbero Contreras Mateos-Hernández Mata-Lorenzo Triguero-Ocaña Sparagano Finn Strube Price Nunn Bartley Höfle Boadella Nisbet Fuente Villar The poultry red mite (PRM), Dermanyssus...
Vaccines, Vol. 7, Pages 189: Efficient Delivery of Dengue Virus Subunit Vaccines to the Skin by Microprojection Arrays Vaccines doi: 10.3390/vaccines7040189 Authors: Muller Depelsenaire Shannon Watterson Corrie Owens Agyei-Yeboah Cheung Zhang Fernando Kendall Young Dengue virus is the most important arbovirus impacting global human health, with an estimated 390 million infections annually, and over half the world’s population at...
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Viruses, Vol. 11, Pages 1082: EWI-2 Inhibits Cell–Cell Fusion at the HIV-1 Virological Presynapse Viruses doi: 10.3390/v11121082 Authors: Whitaker Matheson Perlee Munson Symeonides Thali Cell-to-cell transfer of virus particles at the Env-dependent virological synapse (VS) is a highly efficient mode of HIV-1 transmission. While cell–cell fusion could be triggered at the VS, leading to the formation of syncytia and preventing exponential growth of the infected...
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Water, Vol. 11, Pages 2437: Evaluating the Spatiotemporal Characteristics of Agricultural Drought in Bangladesh Using Effective Drought Index Water doi: 10.3390/w11122437 Authors: Kamruzzaman Hwang Cho Jang Jeong This study aims to assess the spatiotemporal characteristics of agricultural droughts in Bangladesh during 1981–2015 using the Effective Drought Index (EDI). Monthly precipitation data for 36 years (1980–2015) obtained from 27 metrological...
Water, Vol. 11, Pages 2436: Water Scarcity Footprint Analysis of Container-Grown Plants in a Model Research Nursery as Affected by Irrigation and Fertilization Treatments Water doi: 10.3390/w11122436 Authors: Knight Abdi Ingram Fernandez Water scarcity footprint (WSF) was determined for irrigation experiments in 2017 and 2018 for container-grown plants in a specially designed research nursery in Michigan, USA. The system design allowed for the capture of irrigation water...
Water, Vol. 11, Pages 2435: New Methods for the Assessment of Flow Regime Alteration under Climate Change and Human Disturbance Water doi: 10.3390/w11122435 Authors: Shi Liu Yang Xu Feng Yong Cui Li Li Climate change and anthropogenic activities do collectively lead to an alteration of the flow regime, posing a great influence upon the structure and persistence of native biotic communities within river ecosystems. The range of variability approach (RVA)...
Water, Vol. 11, Pages 2434: Precipitation Isotopes Associated with the Duration and Distance of Moisture Trajectory in a Westerly-Dominant Setting Water doi: 10.3390/w11122434 Authors: Wang Du Zhang Shi Jiao Wang A Lagrangian diagnostic adjusted using specific humidity, with 6 h intervals along the trajectory and with lifting condensation level as cloud base height, was employed to identify the moisture source regions around the Tianshan Mountains, northwest China....
Water, Vol. 11, Pages 2433: Feasibility of Multi-Year Forecast for the Colorado River Water Supply: Time Series Modeling Water doi: 10.3390/w11122433 Authors: Plucinski Sun Wang Gillies Eklund Wang The future of the Colorado River water supply (WS) affects millions of people and the US economy. A recent study suggested a cross-basin correlation between the Colorado River and its neighboring Great Salt Lake (GSL). Following that study, the feasibility of using the...
Water, Vol. 11, Pages 2432: Solution Approaches for the Management of the Water Resources in Irrigation Water Systems with Fuzzy Costs Water doi: 10.3390/w11122432 Authors: Sanchis Díaz-Madroñero López-Jiménez Pérez-Sánchez Currently, the management of water networks is key to increase their sustainability. This fact implies that water managers have to develop tools that ease the decision-making process in order to improve the efficiency of irrigation networks, as well as...
Water, Vol. 11, Pages 2428: Real-Time, Smart Rainwater Storage Systems: Potential Solution to Mitigate Urban Flooding Water doi: 10.3390/w11122428 Authors: Liang Matteo Maier Thyer Urban water systems are being stressed due to the effects of urbanization and climate change. Although household rainwater tanks are primarily used for water supply purposes, they also have the potential to provide flood benefits. However, this potential is limited for critical storms, as they...
Water, Vol. 11, Pages 2431: Development and Validation of a Low-Cost Gas Density Method for Measuring Biochemical Methane Potential (BMP) Water doi: 10.3390/w11122431 Authors: Justesen Astals Mortensen Thorsen Koch Weinrich Triolo Hafner Accurate determination of biochemical methane potential (BMP) is important for both biogas research and practice. However, access to laboratory equipment limits the capacity of small laboratories or biogas plants to conduct...
Water, Vol. 11, Pages 2429: Effect of Rain Peak Morphology on Runoff and Sediment Yield in Miyun Water Source Reserve in China Water doi: 10.3390/w11122429 Authors: Xu Zhang Li Wang The research on the impact of rainfall patterns on runoff and sediment yield is still insufficient, especially under natural rainfall conditions. We analyzed the influence of rain peak morphology on runoff and sediment yield based on the data of rainfall, runoff, and sediment in the bare runoff...
Water, Vol. 11, Pages 2430: Characterization of Diffuse Groundwater Inflows into Stream Water (Part II: Quantifying Groundwater Inflows by Coupling FO-DTS and Vertical Flow Velocities) Water doi: 10.3390/w11122430 Authors: Le Lay Thomas Rouault Pichelin Moatar Temperature has been used to characterize groundwater and stream water exchanges for years. One of the many methods used analyzes propagation of the atmosphere-influenced diurnal signal in sediment to infer vertical...
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