Annals of Diagnostic Pathology , 

Pathology in the era of “Personalized Medicine: The need to learn how to integrate multivariate immunohistochemical and “omics” data with clinicopathologic information in a clinically relevant way”

Publication date: Available online 5 October 2019Source: Annals of Diagnostic PathologyAuthor(s): Alberto M. Marchevsky, Ann E. Walts, Mark R. WickAbstract“Personalized medicine” has been proposed as a new paradigm for patient care that, based on the integration of genomics and other “omics” data with clinical and other multidisciplinary information, promises early disease detection, improved outcomes and reduced side effects to therapies. Pathologists have become important participants in this new...

Annals of Diagnostic Pathology

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Next generation sequencing for <em>GNAS</em> uncovers CD34 as a sensitive marker for intramuscular myxoma

Publication date: Available online 5 October 2019Source: Annals of Diagnostic PathologyAuthor(s): Louis Libbrecht, Isabelle Vanden Bempt, Thomas Schubert, Raf Sciot, Christine GalantAbstractBackgroundIntramuscular myxoma is a soft tissue myxoid tumor with a broad morphological differential diagnosis and recent developments have led to the identification of markers that can exclude some, but not all, differential diagnostic entities. However, a sensitive confirmatory marker for intramuscular myxoma...

Annals of Diagnostic Pathology

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Peripheral eosinophilia in primary immunodeficiencies of actin dysregulation: A case series of Wiskott-Aldrich syndrome, CARMIL2 and DOCK8 deficiency and review of the literature

Publication date: Available online 5 October 2019Source: Annals of Diagnostic PathologyAuthor(s): David Kim, Aysegul Uner, Arzu Saglam, Amy Chadburn, Genevieve M. Crane

Annals of Diagnostic Pathology

01:26