Immune checkpoint inhibitors: For how long do we need to release the brakes to achieve the optimum acceleration of immune-mediated anti-tumor response?
Author links open overlay panelAmmarSukariaMisakoNagasakaab
a
Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI, USA
b
Department of Advanced Medical Innovation, St. Marianna University Graduate School of Medicine, Kawasaki, Japan
Received 24 September 2019, Revised 25 September 2019, Accepted 28 September 2019, Available online 18 October 2019.

Figures (1)

1. 
2. 
   

https://doi.org/10.1016/j.oraloncology.2019.09.027Get rights and content
Abstract
In recent years, cancer immunotherapy has emerged as the fourth pillar of cancer therapy alongside surgery, chemotherapy and radiotherapy. We here report an unusual scenario of a patient with advanced metastatic non-small cell lung cancer who was lost to follow up after two cycles of chemo-immunotherapy who later returned to clinic with complete response; suggesting that in some, all that was needed may have been just a few doses of therapy to “release the breaks.”

Keywords
Chemo-immunotherapyComplete responseDuration of therapy
View full text
© 2019 Published by Elsevier Ltd.