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Τετάρτη 16 Οκτωβρίου 2019


Duccio Volterrani, Paola Anna Erba, Ignasi Carrió, H. William Strauss, Giuliano Mariani. Nuclear Medicine Textbook Methodology and Clinical Application, 2 Volumes . Springer Nature Switzerland AG 2019, ISBN 978-3-319-95563-6
European Journal of Nuclear Medicine and Molecular Imaging
03:00
Differentiated thyroid cancer patients potentially benefitting from postoperative I-131 therapy: a review of the literature of the past decade
Abstract Background Since the last major review of literature on the benefit of I-131 therapy, the continued debate on postoperative radioiodine treatment (RIT) in differentiated thyroid carcinoma (DTC) has led to a number of further studies being published on this topic. Aim The aim of the present paper is to report the results of an updated structured review...
European Journal of Nuclear Medicine and Molecular Imaging
Tue Oct 15, 2019 03:00
Amyloid PET Quantification Via End-to-End Training of a Deep Learning
Abstract Purpose Although quantification of amyloid positron emission tomography (PET) is important for evaluating patients with cognitive impairment, its routine clinical use is hampered by complicated preprocessing steps and required MRI. Here, we suggested a one-step quantification based on deep learning using native-space amyloid PET images of different radiotracers acquired from multiple centers. ...
Latest Results for Nuclear Medicine and Molecular Imaging
Mon Oct 14, 2019 03:00
Head-to-head comparison of tau positron emission tomography tracers [ 18 F]flortaucipir and [ 18 F]RO948
Abstract Purpose [18F]flortaucipir binds to paired helical filament tau and accurately identifies tau in Alzheimer’s disease (AD). However, “off-target” binding interferes with the quantification of [18F]flortaucipir in several brain regions. Recently, other tau PET tracers have been developed. Here, we compare [18F]flortaucipir with the novel tau tracer [18F]RO948 head-to-head in vivo. ...
European Journal of Nuclear Medicine and Molecular Imaging
Mon Oct 14, 2019 03:00
Maximum standardized uptake value from quantitative bone single-photon emission computed tomography/computed tomography in differentiating metastatic and degenerative joint disease of the spine in prostate cancer patients
Abstract Objective Qualitative interpretation in bone scan is often complicated by the presence of degenerative joint disease (DJD), especially in the elderly patient. The aim of this study is to compare objectively 99mTc-MDP tracer uptake between DJD and osseous metastases of the spine using semi-quantitative assessment with SPECT SUV. Methods Bone scan...
Annals of Nuclear Medicine
Mon Oct 14, 2019 03:00
Total metabolic tumor volume by 18F-FDG PET/CT for the prediction of outcome in patients with non-small cell lung cancer
Abstract Objective Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are imaging parameters derived from 18F-FDG PET/CT that have been proposed for risk stratification of cancer patients. The aim of our study was to test whether these whole-body volumetric imaging parameters may predict outcome in patients with non-small cell lung cancer (NSCLC). Methods ...
Annals of Nuclear Medicine
Mon Oct 14, 2019 03:00
Characterization of the serotonin 2A receptor selective PET tracer (R)-[ 18 F]MH.MZ in the human brain
Abstract Purpose The serotonin receptor subtype 2A antagonist (5-HT2AR) (R)-[18F]MH.MZ has in preclinical studies been identified as a promising PET imaging agent for quantification of cerebral 5-HT2ARs. It displays a very similar selectivity profile as [11C]MDL 100907, one of the most selective compounds identified thus far for the 5-HT2AR. As [11C]MDL 100907, (R)-[18F]MH.MZ also displays slow brain kinetics in various animal models;...
European Journal of Nuclear Medicine and Molecular Imaging
Sat Oct 12, 2019 03:00
Three-year changes of cortical 18 F-FDG in amnestic vs. non-amnestic sporadic early-onset Alzheimer’s disease
Abstract Purpose To examine and compare longitudinal changes of cortical glucose metabolism in amnestic and non-amnestic sporadic forms of early-onset Alzheimer’s disease and assess potential associations with neuropsychological performance over a 3-year period time. Methods Eighty-two participants meeting criteria for early-onset (< 65 years) sporadic...
European Journal of Nuclear Medicine and Molecular Imaging
Sat Oct 12, 2019 03:00
Comparison of 18 F-FDG PET/MRI, MRI, and 18 F-FDG PET/CT for the detection of synchronous cancers and distant metastases in patients with oropharyngeal and hypopharyngeal squamous cell carcinoma
Abstract Purpose In this prospective study, we sought to compare the clinical utility of fluorodeoxyglucose PET/MRI, MRI, and PET/CT in the detection of synchronous cancers and distant metastases in patients with oropharyngeal and hypopharyngeal squamous cell carcinoma (OHSCC). Methods We examined 198 consecutive patients with biopsy-proven OHSCC who agreed...
European Journal of Nuclear Medicine and Molecular Imaging
Sat Oct 12, 2019 03:00
Augmented planar bone scintigraphy obtained from a whole-body SPECT recording of less than 20 min with a high-sensitivity 360° CZT camera
European Journal of Nuclear Medicine and Molecular Imaging
Sat Oct 12, 2019 03:00
Annual Congress of the European Association of Nuclear Medicine October 12 – 16, 2019 Barcelona, Spain
European Journal of Nuclear Medicine and Molecular Imaging
Tue Oct 01, 2019 03:00
Manual on the proper use of yttrium-90-labeled anti-P-cadherin antibody injection for radionuclide therapy in clinical trials
Abstract We present the guideline for use of yttrium-90-labeled anti-P-cadherin antibody injection for radionuclide therapy in clinical trials on the basis of radiation safety issues in Japan. This guideline was prepared by a study supported by the Ministry of Health, Labour, and Welfare, and approved by the Japanese Society of Nuclear Medicine. Treatment using yttrium-90-labeled anti-P-cadherin antibody injection in Japan should be carried out according to this guideline. Although...
Annals of Nuclear Medicine
Sat Oct 12, 2019 03:00
111 In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis
Abstract Objective Cadherin-17 (CDH17) is a transmembrane protein that mediates cell–cell adhesion and is frequently expressed in adenocarcinomas, including gastric cancer. CDH17 may be an effective diagnostic marker for the staging of gastric cancer. Here, we developed an 111In-labeled anti-CDH17 monoclonal antibody (Mab) as an imaging tracer and performed biodistribution and single-photon emission computed tomography (SPECT)/computed...
Annals of Nuclear Medicine
Sat Oct 12, 2019 03:00
Potential prognostic implications of myocardial thallium-201 and iodine-123-beta-methylpentadecanoic acid dual scintigraphy in patients with Anderson–Fabry disease
Abstract Objectives Information on the relationship between myocardial damage assessed by myocardial scintigraphy and prognosis in patients with Anderson–Fabry disease (AFD) is lacking. We therefore aimed to investigate the prognostic impacts of myocardial thallium-201 (201Tl) and iodine-123 beta-methyl 15-para-iodophenyl 3(R, S)-methylpentadecanoic acid (123I-BMIPP) dual scintigraphy in patients with AFD. ...
Annals of Nuclear Medicine
Fri Oct 11, 2019 03:00
Correction of head movement by frame-to-frame image realignment for receptor imaging in positron emission tomography studies with [ 11 C]raclopride and [ 11 C]FLB 457
Abstract Objective Positron emission tomography (PET) scans of imaging receptors require 60–90-min dynamic acquisition for quantitative analysis. Head movement is often observed during scanning, which hampers the reliable estimation of quantitative parameters. This study evaluated image-based motion correction by frame-to-frame realignment for PET studies with [11C]raclopride and [11C]FLB 457 acquired by an Eminence SET-3000GCT/X and investigated...
Annals of Nuclear Medicine
Fri Oct 11, 2019 03:00

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