Publication date: Available online 14 October 2019Source: Journal of the American College of SurgeonsAuthor(s): Nicole A. Meredyth, Inmaculada de Melo-Martin
Tue Oct 15, 2019 18:55
Abstract Purpose To reveal the function of miR-134 in myocardial ischemia. Methods Real-time PCR and western blotting were performed to measure the expression of miR-134, nitric oxide synthase 3 (NOS3) and apoptotic-associated proteins. Lactic dehydrogenase (LDH) assay, cell counting kit-8 (CCK-8), Hoechst 33342/PI double staining and flow cytometry assay were implemented in H9c2 cells, respectively. MiR-134 mimic/inhibitor was used to regulate miR-134 expression. Bioinformatic analysis and luciferase...
Mon Oct 14, 2019 22:32
Abstract Purpose To evaluate changes in the quantity of elastic fibers in the corpora cavernosa of rats during the natural aging process, and to assess the degree of this change by determining volumetric density (Vv) at different ages via stereological analysis. Methods Forty-eight rats, raised under similar conditions, were subjected to the natural aging process and divided into four groups (G1 to G4), according to age at the time of penectomy (6, 9, 12, and 24 months, respectively). Histological...
Mon Oct 14, 2019 22:32
Abstract Purpose To develop a rabbit model of a short peripheral catheter (SPC) and to observe the effects of different flushing methods on blood vessels. Methods Thirty rabbits were randomly divided into three groups (A, B, and C), with ten rabbits per group. In group A, we used pulsed flush; in group B, we used uniform flush; and no treatment was used in group C. Results We observed that a uniform flush reduced blockage, phlebitis, and exudation compared to a pulsed flush by visual observation....
Mon Oct 14, 2019 22:32
Abstract Purpose To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury Methods Fifty-one Wistar rats were randomly grouped into sham, I/R, and sevoflurane groups. After reperfusion, the structural change of the lung was measured by Smith score, the wet and dry weights (W/D) were determined, malondialdehyde (MDA) myeloperoxidase (MPO) content was determined colorimetrically and by fluorescence, respectively, and matrix metalloprotein-9...
Mon Oct 14, 2019 22:32
Abstract Purpose To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods Fourteen adult wistar rats 300 gr were randomized into two groups: Control group (n=7) and study group (n=7). All the rats underwent sleeve gastrectomy using lineer stapler. In the study group, fibrin glue was used to reinforce the staple-line. The rats were sacrificed 7 days after surgery. The stomach was resected, submerged in saline and exposed to excess pressure to obtain a burst pressure...
Mon Oct 14, 2019 22:32
Abstract Purpose To assess Cyclosporine A (CsA) therapy at an intraperitoneal dose of 15 mg.kg -1 in a rodent model of non-septic renal ischemia. Methods Twenty male Wistar rats were randomized to receive CsA therapy or none therapy before undergoing 30 minutes of renal ischemia followed by reperfusion. Additionally, 10 rats were randomized to undergo the same surgical procedure of the aforementioned animals with neither ischemia nor CsA therapy. Twelve hours after kidney ischemia, the left kidneys...
Mon Oct 14, 2019 22:32
Abstract Purpose To investigate the effect of tanshinone IIA (TIIA) on ventricular remodeling in rats with pressure overload-induced heart failure. Methods Pressure overload-induced heart failure model (abdominal aortic coarctation) was established in 40 rats, which were divided into model and 5, 10 and 20 mg/kg TIIA groups. Ten rats receiving laparotomy excepting abdominal aortic coarctation were enrolled in sham-operated group. The 5, 10 and 20 mg/kg TIIA groups were treated with 5, 10 and 20...
Mon Oct 14, 2019 22:32
AbstractWe present a case of an unexpected cause of bowel ischemia in an intensive care unit patient with herpes simplex virus encephalitis who required an operation. A 79-year-old lady was being worked up and treated for encephalitis with antibiotics and an antiviral. On Day 13, she developed abdominal pain, and an ultrasound showed cholelithiasis but no cholecystitis; thus conservative treatment was advocated. By Day 18, pain localized to the right iliac fossa, and she had an emergency laparotomy...
Mon Oct 14, 2019 03:00
AbstractNasogastric tubes (NGTs) have long been used for various indications, most commonly to decompress the stomach of its contents in intestinal obstruction or after abdominal surgery, to provide enteral feeding or to allow enteral liquid medication administration. Recently greater importance has been given to the correct placement NGTs to avoid serious complications. We present a case of a spontaneously knotted NGT that was identified and safely removed without complications, but which may have...
Mon Oct 14, 2019 03:00
AbstractA vesicourachal diverticulum is a rare congenital anomaly that arises from the incomplete closure of the urachus at the bladder end. We describe a 12-year-old boy who presented with severe persistent right iliac fossa pain associated with subjective fever, nausea, vomiting, and anorexia. A computed tomography (CT) scan of the abdomen and pelvis revealed findings consistent with appendicitis. The patient underwent a laparoscopic appendectomy; however, his postoperative course was remarkable...
Mon Oct 14, 2019 03:00
Twitter is increasingly being used to document academic congresses. This study demonstrates how Twitter use is growing at the Royal Australasian College of Surgeons Annual Scientific Congress, and the reasons surgeons publish content to Twitter. Abstract Background Twitter has been shown to expand the audience and impact of material discussed at medical conferences, however, this phenomenon has not been analysed at the Royal Australasian College of Surgeons Annual Scientific Congress. The...
Mon Oct 14, 2019 11:13
We report the case of a patient with a duodenal perforation secondary to a benign stricture. We made use of intraoperative ultrasound in the acute setting so as to clarify the biliary anatomy and offer definitive surgical management at laparotomy.
Sat Oct 12, 2019 16:04
Abstract Reconstruction of foot structures is challenging because of the need to restore both anatomy and function. Extensor hallucis longus (EHL) excision without reconstruction could result in a flexion deformity of the toe at the interphalangeal joint. In this report, we present a case of the use of a palmaris longus tendon included in a fasciocutaneous radial forearm free flap to reconstruct EHL tendon and soft tissues of the distal foot dorsum. A 41‐year‐old woman presented with a recurrence...
Sat Oct 12, 2019 15:08
AbstractGastrointestinal perforation due to infection, including disseminated histoplasmosis, is a rare cause of the surgical acute abdomen, especially in an apparently healthy patient. We describe a rare case of gastrointestinal histoplasmosis-induced small intestine perforation as the first manifestation of acquired immune deficiency syndrome in a healthy patient. Remarkably, the disease mimicked peritonitis carcinomatosis during explorative laparoscopy.
Sat Oct 12, 2019 03:00
Publication date: Available online 11 October 2019Source: Journal of the American College of SurgeonsAuthor(s): Andrew T. Strong, John Rodriguez, Matthew Kroh, Jeffrey Ponsky, Michael Cline, Kevin El-HayekAbstractIntroductionFor medically refractory diabetic or idiopathic gastroparesis, gastric electrical stimulation (GES) is an excellent option for symptom control; however, a small subset of patients may develop recurrent or persistent symptoms. Per-oral pyloromyotomy (POP) (also described by some...
Fri Oct 11, 2019 14:47
Publication date: Available online 9 October 2019Source: Journal of Surgical EducationAuthor(s): Aimee K. Gardner, Katelyn J. Cavanaugh, Ross E. Willis, Daniel Dent, Henry Reinhart, Mark Williams, Michael S. Truitt, Bradford G. Scott, Brian J. DunkinINTRODUCTIONWe describe a multimethod, multi-institutional approach documenting future competencies required for entry into surgery training.METHODSFive residency programs involved in a statewide collaborative each provided 12 to 15 subject matter experts...
Fri Oct 11, 2019 14:45
Publication date: Available online 9 October 2019Source: Journal of Surgical EducationAuthor(s): Davis H. Payne, Daniel L. Dent, Mohammed J. Al Fayyadh, Jason W. Kempenich, Ross E. Willis, Ronald M. Stewart, John R. Potts IIIPurposeThe Review Committee for Surgery requires a minimum program director (PD) tenure of 6 years. The impact of PD turnover on the performance of program graduates is unknown. We hypothesize that (1) the majority of PDs step down before 6-year tenure and (2) higher PD turnover...
Fri Oct 11, 2019 14:45
AbstractProstate cancer (PCa) is the second most common cancer diagnosed in men globally, after lung cancer. Many patients with PCa are asymptomatic until the tumor has progressed. The prognosis of PCa mainly depends on the presence of metastatic spread. It usually metastasizes to the bone, lung, and liver. Retroperitoneum is an exceedingly rare site for metastatic PCa to occur. We describe a case of a 68-year-old male patient presented for left flank pain and lower limb edema. A retroperitoneal...
Thu Oct 10, 2019 03:00
AbstractCutaneous metastases are rare and often late signs of an internal malignancy; however, this can be the presenting sign in very rare cases. These typically have a characteristic appearance and distribution based on the underlying malignancy but can be difficult to distinguish from other malignant or benign dermatoses. We report a case of a 69-year-old female who presented for elective excision of two cutaneous, fast-growing lesions on the chest wall. The patient’s past medical history is significant...
Thu Oct 10, 2019 03:00
AbstractA 29-year-old female presenting with symptoms of biliary colic was found to have a liver mass compressing the cystic duct. Due to the anatomical placement of the growth, the compressed duct produced symptoms mimicking acute cholecystitis. The mass was diagnosed as focal nodular hyperplasia (FNH) upon biopsy. FNH is commonly found incidentally with nonhepatic clinical presentation or during an unrelated surgical procedure. The scope of this paper is to bring awareness to uncommon causes of...
Thu Oct 10, 2019 03:00
Background: Interferon gamma (IFNγ) and tumor necrosis factor-related weak inducer of apoptosis (TWEAK) molecules seem to have a potential effect on angiogenic factors such as vascular endothelial growth factor (VEGF). The aim of this study was to assess a possible interplay between IFNγ and TWEAK cytokines and VEGF machinery in the different steps of colorectal carcinogenesis. Methods: A total of 92 subjects with colonic adenoma or cancer who underwent screening colonoscopy or surgery were prospectively...
Wed Oct 09, 2019 13:48
Publication date: Available online 7 October 2019Source: Journal of Surgical EducationAuthor(s): K. Lauren Barnes, Lauren McGuire, Gena Dunivan, Andrew L. Sussman, Rohini McKeeObjectiveMedical schools now average approximately 50% female students, yet a disproportionate number of women continue to choose nonsurgical over surgical specialties. Once in training, studies indicate that pervasive gender stereotypes, sexism and harassment negatively affect female surgeons. The aim of this study is to describe...
Tue Oct 08, 2019 17:57
Abstract Background The profunda femoris artery perforator (PAP) flap is gaining popularity in microsurgical reconstruction. To establish a safer flap elevation technique, we focused on the topology of the accessory saphenous vein in the medial thigh area. We hypothesize that including the accessory saphenous vein in a PAP flap results in safer PAP flap transfer with two venous drainage systems. The aim of this study was to describe the anatomical relationship between the perforators and the...
Tue Oct 08, 2019 11:33
Abstract Background The deep branch of the superficial circumflex iliac artery (SCIA) should be included when a large superficial circumflex iliac artery perforator (SCIP) flap is necessary, or when anatomical structures perfused by the deep branch are procured. The aim of this study was first to describe the anatomical features of the “transverse branch” of the deep branch of the SCIA in cadavers, and then to assess the efficacy of its use as a landmark for identification and dissection of the...
Tue Oct 08, 2019 11:33
Abstract Background Traumatic defects of multiple metacarpal bones can be addressed using conventional or vascularized bone grafts. When associated with extensive skin and tendon loss, the treatment becomes more challenging. The aim of the study was to describe the results of using free osteocutaneous fibular flap placed in a new fashion for the reconstruction of complex hand defects. Patients and Methods Six patients with complex hand defects underwent reconstruction using free osteocutaneous...
Mon Oct 07, 2019 21:49
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