The posttranslational modification of HDAC4 in cell biology: Mechanisms and potential targets

The posttranslational modification of HDAC4 in cell biology: Mechanisms and potential targets:

The cell is an independent living entity that undergoes proliferation, differentiation, senescence, apoptosis, and pathology, each process has a strict and complex regulatory system. The expression of histone deacetylase 4 (HDAC4) plays an important role in the life process. This review focuses on the posttranslational modification of HDAC4 in cell biology, providing an important target for future disease treatment.

Abstract

Histone deacetylase 4 (HDAC4) is a member of the HDACs family, its expression is closely related to the cell development. The cell is an independent living entity that undergoes proliferation, differentiation, senescence, apoptosis, and pathology, and each process has a strict and complex regulatory system. With deepening of its research, the expression of HDAC4 is critical in the life process. This review focuses on the posttranslational modification of HDAC4 in cell biology, providing an important target for future disease treatment.