• The New England Journal of Medicine: Endocrinology,
• Ticagrelor in Patients with Stable Coronary Disease and Diabetes

  Patients with both coronary artery disease and type 2 diabetes mellitus are at high risk for cardiovascular events. Platelet-mediated thrombosis is a major mechanism contributing to ischemic events, and the higher risk among patients with diabetes is due in part to increased platelet activation.…

  The New England Journal of Medicine: Search Results in Endocrinology

  Wed Oct 02, 2019 17:00
• Antiplatelet Therapy in Patients with Coronary Disease and Type 2 Diabetes

  Clopidogrel, prasugrel, and ticagrelor are antiplatelet drugs that act by inhibiting the platelet P2Y12 receptor. Any one of them is usually combined with low-dose aspirin as dual antiplatelet therapy in patients who have acute coronary syndromes or who are undergoing coronary stent implantation to…

  The New England Journal of Medicine: Search Results in Endocrinology

  Wed Oct 02, 2019 17:00
• The Journal of Antibiotics - Issue - nature.com science feeds
• Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The discovery of liposidomycin and related compounds with a perspective on their application to new antibiotics

  The Journal of Antibiotics, Published online: 04 October 2019; doi:10.1038/s41429-019-0241-5Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The discovery of liposidomycin and related compounds with a perspective on their application to new antibiotics

  The Journal of Antibiotics - Issue - nature.com science feeds

  Thu Oct 03, 2019 17:00
• Latest Results for Sports Medicine
• Correction to: Relationships Between Dry-land Resistance Training and Swim Start Performance and Effects of Such Training on the Swim Start: A Systematic Review

  No sources of funding were used in the preparation of this article.

  Latest Results for Sports Medicine

  Wed Oct 02, 2019 17:00
• Latest Results for Applied Microbiology and Biotechnology
• Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a

  Abstract Corynebacterium glutamicum is a versatile workhorse for producing industrially important commodities. The design of an optimal strain often requires the manipulation of metabolic and regulatory genes to different levels, such as overexpression, downregulation, and deletion. Unfortunately, few tools to achieve multiple functions simultaneously have been reported. Here, a dual-functional clustered regularly interspaced s

  Latest Results for Applied Microbiology and Biotechnology

  Wed Oct 02, 2019 17:00
• Latest Results for Abdominal Radiology
• Lymph node metastasis in rectal cancer: comparison of MDCT and MR imaging for diagnostic accuracy

  Abstract Purpose To compare the diagnostic accuracies of MDCT and high-resolution MRI (HR-MRI) for regional nodal metastases with different short-axis diameter ranges in rectal cancer patients. Methods Rectal adenocarcinoma patients who underwent both MDCT and HR-MRI before surgery were included. The maxi

  Latest Results for Abdominal Radiology

  Thu Oct 03, 2019 17:00
• Retroperitoneal cystic masses: magnetic resonance imaging features

  Abstract The objective of this review is to discuss the clinical and histopathologic features, MRI characteristics, and management options of retroperitoneal cystic masses. Radiologists should be familiar with the MR imaging characteristics of retroperitoneal cystic masses to allow for a refined differential diagnosis, assist with lesion management, and prevent unnecessary invasive procedures.

  Latest Results for Abdominal Radiology

  Wed Oct 02, 2019 17:00
• Clinical abdominal dual-energy CT: 15 years later

  Abstract Dual-energy CT (DECT) has been available for clinical use in the United States for close to 15 years. Although multiple applications in all areas of the body have been described that are only possible with DECT, the adoption into clinical practice has been slow. This paper will attempt to address many of the impediments the author has encountered from his discussions with radiologists across the country. A hopeful outc

  Latest Results for Abdominal Radiology

  Wed Oct 02, 2019 17:00
• pubmed: sleep apnea
• Familial Aggregation and Heritability of Obstructive Sleep Apnea Using Children Probands.

  Related ArticlesFamilial Aggregation and Heritability of Obstructive Sleep Apnea Using Children Probands. J Clin Sleep Med. 2019 Oct 02;: Authors: Au CT, Zhang J, Cheung JYF, Chan KCC, Wing YK, Li AM Abstract STUDY OBJECTIVES: Previous studies suggest the presence of familial aggregation of obstructive sleep apnea (OSA) in adults. However, similar data on childhood OSA are limited. This family study

  pubmed: sleep apnea

  Thu Oct 03, 2019 03:39
• Alpha-1 Adrenergic-Antagonist Use Increases the Risk of Sleep Apnea: A Nationwide Population-Based Cohort Study.

  Related ArticlesAlpha-1 Adrenergic-Antagonist Use Increases the Risk of Sleep Apnea: A Nationwide Population-Based Cohort Study. J Clin Sleep Med. 2019 Oct 02;: Authors: Su PL, Lin WK, Lin CY, Lin SH Abstract STUDY OBJECTIVES: Decreased upper-airway muscle responsiveness is one of the major phenotypes of obstructive sleep apnea. Use of α1-adrenergic antagonists is correlated with decreased muscle res

  pubmed: sleep apnea

  Thu Oct 03, 2019 03:39
• pubmed: epilepsy treatment
• An Evidence-Based Review On The Use Of Perampanel For The Treatment Of Focal-Onset Seizures In Pediatric Patients.

  Related ArticlesAn Evidence-Based Review On The Use Of Perampanel For The Treatment Of Focal-Onset Seizures In Pediatric Patients. Neuropsychiatr Dis Treat. 2019;15:2789-2798 Authors: Dozières-Puyravel B, Auvin S Abstract Perampanel, a non-competitive AMPA receptor antagonist, is a once-daily oral antiepileptic drug approved for the treatment of focal seizures and primary generalized tonic-clonic sei

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• The Risk Of Seizure-Related Hospitalization Among Older Adults On Levetiracetam Monotherapy: A Retrospective Comparative Cohort Study.

  Related ArticlesThe Risk Of Seizure-Related Hospitalization Among Older Adults On Levetiracetam Monotherapy: A Retrospective Comparative Cohort Study. Neuropsychiatr Dis Treat. 2019;15:2781-2788 Authors: Alzahrani H, Almalag HM, AlRuthia Y, Al-Hussain F, Balkhi B, Almutairi L, Algasem R, De Vol EB, Almarzouqi MR, Alsemari A Abstract Background: Antiepileptic drug monotherapy is the mainstay of treatm

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives.

  Related ArticlesMonitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives. Neuropsychiatr Dis Treat. 2019;15:2773-2780 Authors: Coppola G, Operto FF, Matricardi S, Verrotti A Abstract Epilepsy is associated with a significantly increased risk of developing depressive disorder during adolescence. On the other hand, depression is highly detected in adolescents with epilepsy.

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• Transcranial focused ultrasound pulsation suppresses pentylenetetrazol induced epilepsy in vivo.

  Related ArticlesTranscranial focused ultrasound pulsation suppresses pentylenetetrazol induced epilepsy in vivo. Brain Stimul. 2019 Sep 24;: Authors: Chen SG, Tsai CH, Lin CJ, Lee CC, Yu HY, Hsieh TH, Liu HL Abstract BACKGROUND: Epilepsy is a neurological disorder characterized by abnormal neuron discharge, and one-third of epilepsy patients suffer from drug-resistant epilepsy (DRE). The current mana

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• Rufinamide efficacy and association with phenotype and genotype in children with intractable epilepsy: A retrospective single center study.

  Related ArticlesRufinamide efficacy and association with phenotype and genotype in children with intractable epilepsy: A retrospective single center study. Epilepsy Res. 2019 Sep 28;:106211 Authors: Oesch G, Bozarth XL Abstract OBJECTIVE: To assess long-term efficacy and tolerability of rufinamide in children with epilepsy and a broad spectrum of underlying epileptic etiologies. METHODS: Pat

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus.

  Related ArticlesCDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus. Int J Mol Sci. 2019 Sep 30;20(19): Authors: Kim MJ, Park H, Choi SH, Kong MJ, Kim JE, Kang TC Abstract 2-Cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid methyl ester (CDDO-Me) is a triterpenoid analogue of oleanolic acid that has anti-infl

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• [On the mechanism of therapeutic effects of electrostimulation. Interpretations and predictions based on the results of sleep studies].

  Related Articles[On the mechanism of therapeutic effects of electrostimulation. Interpretations and predictions based on the results of sleep studies]. Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(4. Vyp. 2):15-21 Authors: Pigarev IN, Pigareva ML, Levichkina EV Abstract Based on the studies of the transition from wakefulness to sleep, we propose that therapeutic effect of various types of electrica

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• Endoscope-assisted (with robotic guidance and using a hybrid technique) interhemispheric transcallosal hemispherotomy: a comparative study with open hemispherotomy to evaluate efficacy, complications, and outcome.

  Related ArticlesEndoscope-assisted (with robotic guidance and using a hybrid technique) interhemispheric transcallosal hemispherotomy: a comparative study with open hemispherotomy to evaluate efficacy, complications, and outcome. J Neurosurg Pediatr. 2018 11 09;23(2):187-197 Authors: Chandra PS, Subianto H, Bajaj J, Girishan S, Doddamani R, Ramanujam B, Chouhan MS, Garg A, Tripathi M, Bal CS, Sarkar C, Dwivedi R, Sapr

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• Neuropsychological outcome after subtemporal versus transsylvian approach for selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy: a randomised prospective clinical trial.

  Related ArticlesNeuropsychological outcome after subtemporal versus transsylvian approach for selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy: a randomised prospective clinical trial. J Neurol Neurosurg Psychiatry. 2018 10;89(10):1057-1063 Authors: Vogt VL, Delev D, Grote A, Schramm J, von Lehe M, Elger CE, Witt JA, Helmstaedter C Abstract OBJECTIVE: To compare the ef

  pubmed: epilepsy treatment

  Thu Oct 03, 2019 03:01
• SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents
• The Silencing of SFRP2 Expression in ESCC Is Due to Methylation of the Gene Promoter

  Technology in Cancer Research &Treatment, Volume 18, Issue , January 2019. Objective:Our aim of the study was to investigate the expression level and methylation status of the secreted frizzled-related protein 2 in esophageal squamous cell carcinoma and to evaluate the clinical utility of the marker.Material and Methods:We first used Immunohistochemistry (ICH) to explore the expression level of secreted frizzled-related protein 2 protein in esoph

  SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents

  Wed Oct 02, 2019 21:06
• SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
• A case report of rectal adenocarcinoma with intrahepatic cholangiocarcinoma of the liver

  Journal of International Medical Research, Ahead of Print.

  SAGE Publications Ltd: Journal of International Medical Research: Table of Contents

  Thu Oct 03, 2019 20:48
• Incarcerated recurrent inguinal hernia as a cause of secondary torsion of the greater omentum: a rare case report and literature review

  Journal of International Medical Research, Ahead of Print.

  SAGE Publications Ltd: Journal of International Medical Research: Table of Contents

  Thu Oct 03, 2019 04:41
• Effects of dasatinib on CD8+T, Th1, and Treg cells in patients with chronic myeloid leukemia

  Journal of International Medical Research, Ahead of Print.

  SAGE Publications Ltd: Journal of International Medical Research: Table of Contents

  Thu Oct 03, 2019 03:48
• Synbiotics for prevention of ventilator-associated pneumonia: a probiotics strain-specific network meta-analysis

  Journal of International Medical Research, Ahead of Print.

  SAGE Publications Ltd: Journal of International Medical Research: Table of Contents

  Thu Oct 03, 2019 02:14
• Wiley: Dermatologic Therapy: Table of Contents
• Etiology and treatment of dandruff according to Persian medicine

  Abstract Scalp dandruff is one of the most common complaints of patients visiting dermatologic clinics. It has significant influence on the self‐confidence and social image of the individuals it affects. The current study aimed to analyze this problem from the viewpoint of Persian medicine. This paper is a literature review in which the text of selected books on Persian medicine is investigated using content analysis based on the theoretical sa

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 05:41
• Treatment of Demodex‐Associated Inflammatory Skin Conditions: A Systematic Review

  ABSTRACT Bacterial folliculitis, rosacea, and other common skin conditions have been linked to infestation by Demodex mites (human demodicosis). Currently, there is little guidance for treatment of inflammatory conditions associated with demodicosis. Thus, the objective of this review is to evaluate the efficacy and safety of treatments utilized for Demodex infestation. Pubmed (1946 to January 2019) and Embase (1947 to January 2019) were searche

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 05:40
• Bioactive: A New Era of Bioactive Ingredients in Topical Formulations for Inflammatory Dermatoses

  Abstract Moisturization is the pillar of daily skin care, and has significant benefit in improving hydration, strengthening the skin barrier, and ameliorating inflammatory dermatoses. Bioactive ingredients such as endocannabinoids, bioactive lipids, growth factors, microbiome modulators, and antioxidant enzymes are increasingly being incorporated into moisturizer formulations. These novel ingredients have been shown to improve skin barrier funct

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 05:39
• Effects of family constellation seminars on itch in patients with atopic dermatitis and psoriasis: A patient preference controlled trial

  Abstract Family dynamics plays a major role in itch related dermatoses. The aim of the study was to evaluate the effectiveness of family constellation seminars (FCS) in the decrease of itch in atopic dermatitis (AD) and psoriasis. 31 adult patients with chronic itch (16 with AD and 15 with psoriasis) were allocated to intervention group (FCS + G) and control group (CG). Patients from FCS + G have participated in a series of 4 FCS for 3 months. D

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 05:39
• Platelet gel in wound treatment in patient with pemphigus vulgaris and type 2 diabetes mellitus: case report

  Abstract Treatment of wounds, especially in patients with systemic diseases, is very difficult and time consuming, and it represents great challenge. Complications like infections and impaired healing are regularly seen in these patients, sometimes leaving almost no other treating option, but amputation surgery. In wound healing process platelets play one of key roles, both in hemostasis, and, by releasing many growth factors, in reepithelizati

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:33
• Real life experience on effectiveness and tolerability of topical ivermectin in papulopustular rosacea and anti‐parasitic effect on Demodex mites

  Abstract Background Ivermectin is a drug approved for the treatment of papulopustular rosacea. Although clinical guidelines recommend the use of ivermectin as the first‐line treatment in patients with almost clear and mild rosacea, studies concerning its use on them are lacking. Objective This study investigated the effectiveness and the tolerability of ivermectin in almost clear to severe rosacea and assessed the anti‐parasitic effect

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:31
• Oral bicalutamide for female pattern hair loss: a pilot study

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:31
• Efficacy and Safety of Oral Silymarin in Comparison with Oral Doxycycline and their Combination Therapy in the Treatment of Acne Vulgaris

  ABSTRACT Background Two factors of oxidative stress and inflammatory processes are implicated in pathogenesis of acne vulgaris. Silymarin has antioxidant and anti‐inflammatory activities. This study was done to evaluate the effect of oral silymarin in the treatment of acne vulgaris compared to doxycycline and also their combination therapy. Materials and Methods This randomized controlled trial (RCT) was performed on 60 patients with a

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:30
• Immediate post‐irradiation dermoscopic vascular changes versus purpura as a therapeutic endpoint in pulsed dye laser treatment of port wine stains

  Abstract Pulsed dye laser (PDL) is the treatment of choice for port wine stain (PWS) and development of purpura is considered a therapeutic endpoint. Changes in PWS vasculature observed by dermoscopy immediately after laser irradiation has been suggested to predict the minimal effective fluence. The current study aimed at comparing these changes with purpura as a therapeutic endpoint. Fifty‐six PWS patients, randomized into 2 groups, received 5

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:29
• Self‐administration of Icatibant in Acute Attacks of Type I Hereditary Angioedema: a Case Report and Review of Hereditary Angioedema

  Abstract Hereditary angioedema (HAE) is a rare group of genetic disease characterized by non‐itchy swelling of subcutaneous and submucosal tissues of the extremities, genitalia, gastrointestinal tract and upper airways which can be life threatening. Moreover, unpredictability and recurrence of HAE attacks significantly affect patients’ quality of life. Short and long‐term prophylaxis is used to decrease severity and frequency of attacks, but dur

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:29
• Combined intravenous pulse and topical corticosteroid therapy for severe alopecia areata in children: comparison of two regimens

  Abstract There is no universally accepted treatment for severe pediatric alopecia areata (AA). This prospective study comprised 73 patients (aged 1‐18 years) with severe AA (>30% of scalp surface area): 37 received 1‐day intravenous dexamethasone pulses (1‐DP) and 36 received 3‐day pulses (3‐DP), monthly, for 6‐12 months. Also, all patients applied topical clobetasol propionate under plastic wrap occlusion. Patients achieving >50% regrowth were

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:19
• Adalimumab in severe plaque psoriasis of childhood: a multi‐center, retrospective real‐life study up to 52 weeks observation

  Abstract Objective To determine drug effectiveness and safety of the tumor necrosis factor (TNF)‐alpha blocker monoclonal antibody adalimumab in a real‐life cohort of 54 children and/or adolescents with severe plaque psoriasis. Methods Retrospective, multicentre analysis over a 52 week period. Efficacy was determined by the percentage of patients achieving PASI 75 and PASI 90 at weeks 16, 24, and 52 and the response in biologic‐naïve ve

  Wiley: Dermatologic Therapy: Table of Contents

  Thu Oct 03, 2019 02:18