Journal of Human Evolution
- The dental remains from the Early Upper Paleolithic of Manot Cave, IsraelPublication date: Available online 11 October 2019Source: Journal of Human EvolutionAuthor(s): Rachel Sarig, Cinzia Fornai, Ariel Pokhojaev, Hila May, Mark Hans, Bruce Latimer, Omry Barzilai, Rolf Quam, Gerhard W. WeberAbstractThis study presents the dental remains discovered at Manot Cave (MC), Western Galilee, Israel. The cave contains evidence for human occupation during the Early Upper Paleolithic period (46–33 ka) mainly of Early Ahmarian (∼
- Physicians prescribe adrenaline autoinjectors, do parents use them when needed?Publication date: Available online 11 October 2019Source: Allergologia et ImmunopathologiaAuthor(s): S. Esenboga, M. Kahveci, P.G. Cetinkaya, U.M. Sahiner, O. Soyer, B. Buyuktiryaki, B.E. SekerelAbstractBackgroundAnaphylaxis is a sudden, severe, and potentially life-threatening allergic reaction, affecting a portion of allergic patients. Adrenaline is the first-line medication for anaphylaxis and available in many parts of the world as adrenaline
- Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteriaPublication date: Available online 11 October 2019Source: Allergologia et ImmunopathologiaAuthor(s): A. Akan, E. Dibek-Mısırlıoğlu, E. Civelek, E. Vezir, C.N. KocabaşAbstractBackgroundAtopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evalu
- Associations among neighborhood greenspace, neighborhood violence, and children’s asthma control in an urban cityPublication date: Available online 11 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Kelli DePriest, Arlene Butz, Frank C. Curriero, Nancy Perrin, Deborah Gross
- Anti-inflammatory reliever therapy for asthmaPublication date: Available online 11 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Brian Lipworth, Rory Chan, Chris RuiWen Kuo
- Soft tissue conduction is the third mode of auditory stimulationPublication date: Available online 12 October 2019Source: Auris Nasus LarynxAuthor(s): Haim Sohmer
- Quel parcours de soins proposer aux patients atteints d’une embolie pulmonaire ? Quels malades traiter en ambulatoire ?Publication date: Available online 12 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): L. Bertoletti, A. Delluc, P. Frappé, P.-M. Roy, O. Sanchez, Recommandations de bonne pratique pour la prise en charge de la MVTE
- Quand et comment rechercher une hypertension pulmonaire thromboembolique chronique (HTP-TEC) après une embolie pulmonaire ?Publication date: Available online 12 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): F. Parent, O. Sanchez, groupe de travail Recommandations de bonne pratique pour la prise en charge de la MVTE
- Embolie pulmonaire et agénésie de veine cave inférieure : une association inhabituellePublication date: Available online 12 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): S. Van Laethem, R. Peché, V. Mercier, M. Moradi, P. Cauchie, A. Van MeerhaegheRésuméIntroductionL’agénésie de la veine cave inférieure (AVCI) est une anomalie vasculaire rare, généralement révélée au décours de thromboses veineuses profondes (TVP) et plus rarement d’embolies pulmonaires, dans une population jeune dont la clinique peut être atypiqu
- Tabac et travailPublication date: Available online 12 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): V. Le Denmat, J.-D. DewitteRésuméIntroductionLes baromètres santé réalisés en France depuis plus de 15 ans montrent des différences de prévalence du tabagisme en fonction du statut d’activité et des catégories socioprofessionnelles. Les relations entre tabac et travail ne se limitent pas à cela.États des connaissancesLe tabagisme des salariés est
- Utilisation concomitante du nivolumab et d’immunosuppresseurs chez un patient greffé rénalPublication date: Available online 12 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): H. Pluchart, L. Ferrer, D. Giovannini, R. Tetaz, J. Pinsolle, O. Stephanov, M. Giaj Levra, D. Moro-Sibilot, A.-C. ToffartRésuméIntroductionPlusieurs immunothérapies ont obtenu une autorisation de mise sur le marché en 1re et en 2e ligne des cancers bronchiques non à petites cellules avancés ou métastatiques grâce aux résultats de plusieurs essais
- Règlement général sur la protection des données pour MASK-air® (application mobile rhinite et l’asthme)Publication date: Available online 11 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): D. Laune, S. Arnavielhe, F. Viart, A. Bedbrook, J. Mercier, G. Lun San Luk, G. deVries, O. Spreux, J. BousquetRésuméLe règlement général sur la protection des données (RGPD) encadre le traitement des données personnelles dans l’Union européenne. Le contexte juridique s’adapte pour suivre les évolutions des technologies et de nos sociétés. Ce nouve
- Comment et chez qui faut-il surveiller les traitements anticoagulants ?Publication date: Available online 11 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): D.-M. Smadja, N. Gendron, O. Sanchez, groupe de travail Recommandations de bonne pratique pour la prise en charge de la MVTE
- Quelle est la prise en charge des thromboses veineuses profondes sous-poplitées ?Publication date: Available online 11 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): I. Quéré, J.P. Galanaud, O. Sanchez, pour le groupe de travail Recommandations de bonne pratique pour la prise en charge de la MVTE
- Quelles sont les particularités thérapeutiques au cours du syndrome des antiphospholipides ?Publication date: Available online 11 October 2019Source: Revue des Maladies RespiratoiresAuthor(s): Y. Benhamou, A. Delluc, A-M. Fischer, O. Sanchez, groupe de travail Recommandations de bonne pratique pour la prise en charge de la MVTE
- Illustration of a fatal radiation-induced lung aneurysm: Is central lung stereotactic radiotherapy to be banned?Publication date: Available online 11 October 2019Source: Cancer/RadiothérapieAuthor(s): B. Ledoux, M. Dupont, F. Duplaquet, L. Pirard, S. Ocak, M. Wanet, V. RemouchampsAbstractStereotactic body radiation therapy is still controversial for inoperable patients with central lung lesion. We report the case of a 59-year-old woman with previous history of head and neck squamous cell carcinoma who was treated by lung stereotactic body irradiation for a
- Hypofractionated radiation therapy for invasive breast cancer: From moderate to extreme protocolsPublication date: Available online 11 October 2019Source: Cancer/RadiothérapieAuthor(s): S. Rivera, J.-M. Hannoun-LéviAbstractAdjuvant irradiation is the standard treatment after breast conservative surgery. Normofractionated regimen with an overall treatment time of 5 to 6 weeks is often considered as a limiting factor for irradiation compliance. In order to answer this issue, moderate and more recently extreme hypofractionated protocols appeare
Traditional dysphagia therapy
- MIVAT: the last 2 years experience, tips and techniques after more than 10 years.Related ArticlesMIVAT: the last 2 years experience, tips and techniques after more than 10 years. Surg Endosc. 2018 05;32(5):2340-2344 Authors: Bellotti C, Capponi MG, Cinquepalmi M, Castagnola G, Marchetta S, Mallozzi F, Pezzatini M, Brescia A Abstract BACKGROUND: Minimally invasive video-assisted thyroidectomy (MIVAT) has been introduced into clinical practice by Miccoli in the late 1990s (Miccoli
- Potential therapeutic effect of SO₂ on fibrosis.Related ArticlesPotential therapeutic effect of SO₂ on fibrosis. Histol Histopathol. 2019 Oct 11;:18169 Authors: Wang XB, Cui H, Du JB Abstract Fibrosis is a pathological feature of most chronic diseases and leads to the dysfunction of various organs. However, there is currently no effective method for treating fibrosis. In recent years, a small gas, sulfur dioxide (SO₂), which can be generated endog
- Radioactive iodine therapy for pediatric Graves' disease: a single-center experience over a 10-year period.Related ArticlesRadioactive iodine therapy for pediatric Graves' disease: a single-center experience over a 10-year period. J Pediatr Endocrinol Metab. 2019 Oct 11;: Authors: Kaplowitz PB, Jiang J, Vaidyanathan P Abstract Introduction Only about 30% of pediatric patients with Graves' hyperthyroidism achieve remission with medical therapy, and therefore radioactive iodine (RAI) therapy is often used a
- Submental Muscle Activation During Lingual Tasks in Healthy Adults.Related ArticlesSubmental Muscle Activation During Lingual Tasks in Healthy Adults. J Nutr Health Aging. 2018;22(9):1133-1137 Authors: Oommen ER, Kim Y Abstract OBJECTIVE: Lingual strengthening exercises are established to improve lingual function, thereby oral swallowing. This study measured submental muscle activation during maximum isometric pressure (MIP) lingual tasks in healthy adults, tasks th
- [Medical complications in patients with neurocognitive disorders].Related Articles[Medical complications in patients with neurocognitive disorders]. MMW Fortschr Med. 2018 Mar;160(5):45-48 Authors: Hewer W, Tomandl B, Marburger C PMID: 29556997 [PubMed - indexed for MEDLINE]
The European Gastrointestinal Motility Society
- Ghrelin abates bacterial translocation following burn injury by improving gastric emptyingIn severe cutaneous burn injury, burn‐induced gastrointestinal dysmotility correlates with the systemic translocation of gram‐negative gut bacteria implicated in multiple organ failure. By improving the dysmotility, ghrelin abates the concomitant bacterial translocation. Abstract Background In severe burns, increased intestinal permeability facilitates bacterial translocation, resulting in systemic endotoxemia and multi‐organ failure. We inv
- Ex-vivo surgical model for "Barbed Snore Surgery": a feasibility study.Related ArticlesEx-vivo surgical model for "Barbed Snore Surgery": a feasibility study. Eur Arch Otorhinolaryngol. 2019 Oct 10;: Authors: Rinaldi V, Costantino A, Moffa A, Casale M Abstract INTRODUCTION: The "Barbed Snore Surgery" is one of the last technical innovations in palatal surgery for Obstructive Sleep Apnea. The availability of a low-cost surgical model able to replicate tissue consistency
- Decoding supraglottic stenosis.Related ArticlesDecoding supraglottic stenosis. Eur Arch Otorhinolaryngol. 2019 Oct 10;: Authors: Colliard A, Ishii A, De Sandre C, Gorostidi F, Sandu K Abstract OBJECTIVE: Supraglottic stenosis (SPGS) is a rare condition and little is known about its optimal management. Its etiologies are varied and depend on the age group. Here, we review our institution's series of patients and propose treatment s
- Investigation of Skull-Based CSF Leak Repair: A Single Institution Comprehensive Study of 116 Cases over 10 Years.Related ArticlesInvestigation of Skull-Based CSF Leak Repair: A Single Institution Comprehensive Study of 116 Cases over 10 Years. World Neurosurg. 2019 Oct 08;: Authors: Dai JB, Del Signore AG, Govindaraj S, Bederson JB, Iloreta AMC, Shrivastava RK Abstract BACKGROUND: CSF leaks have been historically difficult to diagnose and treat as their etiology can widely vary. There are currently insufficient
- "Exp Ther Med"[jour]; +52 new citations52 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Exp Ther Med"[jour] These pubmed results were generated on 2019/10/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
- Osteochondroma of the Distal Volar Thumb.Related ArticlesOsteochondroma of the Distal Volar Thumb. Eplasty. 2019;19:ic17 Authors: Chao J, Brummund D, Datiashvilli R PMID: 31602286 [PubMed]
- A review of timelines for metastasis in cutaneous squamous cell carcinoma, and evidence for clinical follow-up.Related ArticlesA review of timelines for metastasis in cutaneous squamous cell carcinoma, and evidence for clinical follow-up. J Plast Reconstr Aesthet Surg. 2019 Sep 27;: Authors: Chu TSM, Chang C, Rannan-Eliya S PMID: 31601538 [PubMed - as supplied by publisher]
Audiology
- Frequency Therapeutics Begins Phase 2a Testing on Drug to Cure Hearing LossFrequency Therapeutics has commenced dosing in a Phase 2a clinical study of FX-322, a drug designed to regenerate auditory hair cells and restore hearing function. This multi-center, randomized, double-blind, placebo-controlled study aims to further establish the positive hearing signal observed in a Phase 1/2 study, including improved clarity of sound and word recognition. Frequency also hopes to evaluate safety and define the potential dosing r
- Fully integrated 18F-FDG PET/MR in large vessel vasculitis.Related ArticlesFully integrated 18F-FDG PET/MR in large vessel vasculitis. Q J Nucl Med Mol Imaging. 2019 Oct 09;: Authors: Padoan R, Crimì F, Felicetti M, Padovano F, Lacognata C, Stramare R, Quaia E, Cecchin D, Bui F, Zucchetta P, Schiavon F Abstract BACKGROUND: To evaluate the usefulness of [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET)/magnetic resonance (MR) in large vessels
- Prognostic importance of PSA response in patients who received Lutetium-177 PSMA treatment for castration resistant prostate cancer.Related ArticlesPrognostic importance of PSA response in patients who received Lutetium-177 PSMA treatment for castration resistant prostate cancer. Q J Nucl Med Mol Imaging. 2019 Oct 09;: Authors: Soydal C, Araz M, Urun Y, Nak D, Ozkan E, Kucuk NO Abstract BACKGROUND: This study aims to analyze the prognostic importance of serum PSA response in patients who received radioligand therapy (RLT) with Lu
European Journal of Nuclear Medicine and Molecular Imaging
- Characterization of the serotonin 2A receptor selective PET tracer (R)-[ 18 F]MH.MZ in the human brainAbstract Purpose The serotonin receptor subtype 2A antagonist (5-HT2AR) (R)-[18F]MH.MZ has in preclinical studies been identified as a promising PET imaging agent for quantification of cerebral 5-HT2ARs. It displays a very similar selectivity profile as [11C]MDL 100907, one of the most selective compounds identified thus far for the 5-HT2AR. As [11C]MDL 100907, (R)-[18F]MH.MZ also disp
- Three-year changes of cortical 18 F-FDG in amnestic vs. non-amnestic sporadic early-onset Alzheimer’s diseaseAbstract Purpose To examine and compare longitudinal changes of cortical glucose metabolism in amnestic and non-amnestic sporadic forms of early-onset Alzheimer’s disease and assess potential associations with neuropsychological performance over a 3-year period time. Methods Eighty-two participants meetin
- Comparison of 18 F-FDG PET/MRI, MRI, and 18 F-FDG PET/CT for the detection of synchronous cancers and distant metastases in patients with oropharyngeal and hypopharyngeal squamous cell carcinomaAbstract Purpose In this prospective study, we sought to compare the clinical utility of fluorodeoxyglucose PET/MRI, MRI, and PET/CT in the detection of synchronous cancers and distant metastases in patients with oropharyngeal and hypopharyngeal squamous cell carcinoma (OHSCC). Methods We examined 198 con
- Postnatal intermittent hypoxia enhances phrenic and reduces vagal‐related upper airway motor activities in rats by epigenetic mechanismsAbstract Periods of apnoeas, commonly observed in premature and newborns, are an important risk factor for the development of cardiorespiratory diseases in adulthood. In the present study, we evaluated changes in pulmonary ventilation and respiratory motor pattern in juvenile and adult rats exposed to postnatal chronic intermittent hypoxia (pCIH). Newborn male Holtzman rats (P1) were submitted to pCIH [6% O2 for 30 s, every 9 min, 8 hours a day
- Oxygen and brain death; back from the brinkNew Findings •What is the topic of this review? To explore the unique evolutionary origins of the human brain and critically appraise its energy budget including limits of oxygen and glucose deprivation during anoxia and ischaemia. •What advances does it highlight? The brain appears to be more resilient to substrate depletion than traditionally thought highlighting greater resilience and an underappreciated capacity for function
- Thyroid nodules with Hürthle cells: the malignancy risk in relation to the FNA outcome categoryAbstract Purpose The aim was to find whether the presence of Hürthle cells (HC) in a smear influences the categorization of FNA results or the risk of malignancy (RoM) of particular categories of cytological diagnosis. Methods 25,220 FNA performed in a single center in years 2005–2017 were a
- Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE)Abstract Background Weight loss is a milestone in the prevention of chronic diseases associated with high morbility and mortality in industrialized countries. Very-low calorie ketogenic diets (VLCKDs) are increasingly used in clinical practice for weight loss and management of obesity-related comorbidities. Despite evidence on the clinical benefits of VLCKDs is rapidly emerging,
- Sick fat : the good and the bad of old and new circulating markers of adipose tissue inflammationAbstract Adipose tissue (AT) is one of the largest endocrine organs contributing to metabolic homeostasis. The functional pleiotropism of AT depends on its ability to secrete a large number of hormones, cytokines, extracellular matrix proteins and growth factors, all influencing many local and systemic physiological and pathophysiological processes. In condition of chronic positive energy balance, adipocyte expansion, hypoxia
- Expression of miR-217 and HIF-1α/VEGF pathway in patients with diabetic foot ulcer and its effect on angiogenesis of diabetic foot ulcer ratsAbstract Objective To investigate the expression of miR-217 and HIF-1α/VEGF pathway in patients with diabetic foot ulcer (DFU) and its effect on angiogenesis in DFU rats. Methods The serum levels of miR-217, HIF-1α and VEGF were detected in DFU and simple diabetes mellitus (DM) patients, and
- Effect of long- and short-chain perfluorinated compounds on cultured thyroid cells viability and response to TSHAbstract Purpose Perfluorinated chemicals are widespread pollutants persistent in the environment with links to some major health issues. The two main compounds, perfluoro-octanoic acid (PFOA) and perfluoro-alkyl sulphonate (PFOS), were recently classified as carcinogenetic and thus their use has been restricted. Short-chain PFCs were recently developed as an alternative, but no
- Cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery.Related ArticlesCost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery. Int J Surg. 2019 Oct 08;: Authors: Yang F, Walker S, Richardson G, Stephens T, Phull M, Thompson A, Pearse RM, Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group Abstract BACKGROUND: Patients undergoing emergency abdominal surgery are exposed to hi
- Interrater reliability of a method to assess hypothalamic involvement in pediatric adamantinomatous craniopharyngioma.Related ArticlesInterrater reliability of a method to assess hypothalamic involvement in pediatric adamantinomatous craniopharyngioma. J Neurosurg Pediatr. 2019 Oct 11;:1-6 Authors: Whelan R, Prince E, Mirsky DM, Naftel R, Bhatia A, Pettorini B, Avula S, Staulcup S, Alexander AL, Meier M, Hankinson TC Abstract OBJECTIVE: Pediatric adamantinomatous craniopharyngiomas (ACPs) are histologically benign b
- Extraordinary case presentations in pediatric pituitary adenoma: report of 6 cases.Related ArticlesExtraordinary case presentations in pediatric pituitary adenoma: report of 6 cases. J Neurosurg Pediatr. 2019 Oct 11;:1-8 Authors: Meyer J, Perry A, Oushy S, Graffeo CS, Carlstrom LP, Meyer FB Abstract Pediatric pituitary adenomas (PPAs) are rare neoplasms with a propensity for unusual presentations and an aggressive clinical course. Here, the authors describe 6 highly atypical PPAs t
- Detection of epileptogenic focus using advanced dynamic statistical parametric mapping with magnetoencephalography in a patient with MRI-negative focal cortical dysplasia type IIB.Related ArticlesDetection of epileptogenic focus using advanced dynamic statistical parametric mapping with magnetoencephalography in a patient with MRI-negative focal cortical dysplasia type IIB. J Neurosurg Pediatr. 2019 Oct 11;:1-5 Authors: Chang WS, Nakajima M, Ochi A, Widjaja E, Rutka JT, Yau I, Baba S, Otsubo H Abstract Advanced dynamic statistical parametric mapping (AdSPM) with magnetoencepha
- Posterior transdural approach for odontoidectomy in a child: case report.Related ArticlesPosterior transdural approach for odontoidectomy in a child: case report. J Neurosurg Pediatr. 2019 Oct 11;:1-5 Authors: Archer J, Thatikunta M, Jea A Abstract The transoral transpharyngeal approach is the standard approach to resect the odontoid process and decompress the cervicomedullary spinal cord. There are some significant risks associated with this approach, however, including
- Association of cognitive function with cerebral blood flow in children with moyamoya disease.Related ArticlesAssociation of cognitive function with cerebral blood flow in children with moyamoya disease. J Neurosurg Pediatr. 2019 Oct 11;:1-7 Authors: Kazumata K, Tokairin K, Sugiyama T, Ito M, Uchino H, Osanai T, Kawabori M, Nakayama N, Houkin K Abstract OBJECTIVE: The cognitive effects of main cerebral artery occlusive lesions are unclear in children with moyamoya disease (MMD). The authors a
- Management of sterile abdominal pseudocysts related to ventriculoperitoneal shunts.Related ArticlesManagement of sterile abdominal pseudocysts related to ventriculoperitoneal shunts. J Neurosurg Pediatr. 2019 Oct 11;:1-5 Authors: Erwood A, Rindler RS, Motiwala M, Ajmera S, Vaughn B, Klimo P, Chern JJ Abstract OBJECTIVE: There are many known complications associated with CSF shunts. One of the more rare ones is a sterile abdominal pseudocyst due to decreased peritoneal absorption. T
- Neuroblastoma with intracerebral metastases and the need for neurosurgery: a single-center experience.Related ArticlesNeuroblastoma with intracerebral metastases and the need for neurosurgery: a single-center experience. J Neurosurg Pediatr. 2019 Oct 11;:1-6 Authors: Fleck S, Marx S, Bobak C, Richter V, Nowak S, Rafaee EE, Siebert N, Ehlert K, Schroeder HWS, Lode HN Abstract OBJECTIVE: Intracerebral metastases in neuroblastoma patients are rare, and information about the indication for and the outcom
BioMed Research International
- Rs4846049 Polymorphism at the 3′-UTR of MTHFR Gene: Association with Susceptibility to Childhood Acute Lymphoblastic LeukemiaBackground. Accumulating evidence has suggested the polymorphisms of methylenetetrahydrofolate reductase (MTHFR) were associated with susceptibility to childhood acute lymphoblastic leukemia (ALL). However, the known conclusions of currently known polymorphic loci (677 C > T and 1298 A > C) remain controversial. This study was to investigate new genetic biomarkers for ALL by analyzing the MTHFR polymorphisms at the 3′-untranslated region, which i
- Prediction of MicroRNA and Gene Target in Synovium-Associated Pain of Knee Osteoarthritis Based on Canonical Correlation AnalysisInflammation plays a central role in knee osteoarthritis (OA) pathogenesis (C. R. Scanzello, 2017). The synovial membrane inflammation is associated with disease progression and represents a primary source of agony in knee OA (L. A. Stoppiello et al., 2014). Many inflammatory mediators may have biomarker utility. To identify synovium related to knee OA pain biomarkers, we used canonical correlation analysis to analyze the miRNA-mRNA dual expressi
- Sarcocystis spp. in Romanian Slaughtered Cattle: Molecular Characterization and Epidemiological Significance of the FindingsSpecies of the genus Sarcocystis are recognized as protozoan parasites infecting a wide range of animals, including humans. This study aimed to provide data on the occurrence, genetic characterization, and epidemiological significance of Sarcocystis spp. in cattle destined for human consumption in Romania. A total of 117 heart samples from slaughtered cattle in three southwestern Romanian counties (Dolj, Timiș, and Gorj) were analyzed in order to
- Extended-Spectrum β-Lactamases among Enterobacteriaceae Isolated from Urinary Tract Infections in Gaza Strip, PalestineBackground. Extended-spectrum β-lactamase-producing organisms causing urinary tract infections are increasing in incidence and pose a major impendence to health-care facility, having limited therapeutic options. This study aimed to assess the prevalence of ESBLs in Enterobacteriaceae isolates causing urinary tract infections in Gaza strip, Palestine, and to characterize β-lactamase types and associated resistance genes. Methods. Eighty-five Enter
- Preliminary Study on the Efficient Electrohysterogram Segments for Recognizing Uterine Contractions with Convolutional Neural NetworksBackground. Uterine contraction (UC) is the tightening and shortening of the uterine muscles which can indicate the progress of pregnancy towards delivery. Electrohysterogram (EHG), which reflects uterine electrical activities, has recently been studied for UC monitoring. In this paper, we aimed to evaluate different EHG segments for recognizing UCs using the convolutional neural network (CNN). Materials and Methods. In the open-access Icelandic
- Diabetes and Younger Age Are Vital and Independent Risk Factors for Acute Pancreatitis in Patients with Severe HypertriglyceridemiaBackground. The incidence of hypertriglyceridemia-induced acute pancreatitis (HIAP) is increasing worldwide, and now it is the third leading cause of acute pancreatitis in the United States. But, there are only 5% of patients with severe hypertriglyceridemia (>1000 mg/dl) which might generate acute pancreatitis. In order to explore which part of the patients is easy to develop into pancreatitis, a case-control study was performed by us to conside
- Psychosocial Predictors of BruxismObjectives. The study aimed to investigate the psychosocial predictors of bruxism. The association of various psychosocial factors such as alexithymia, emotional processing, state and trait anxiety, and stress with awake bruxism was analysed. Methods. The study involved 52 volunteers diagnosed with awake bruxism. The toolkit that was used included the Toronto Alexithymia Scale (TAS-20), the Emotional Processing Scale (EPS), the Cohen Perceived St
- The Prominent Role of HMGA Proteins in the Early Management of Gastrointestinal CancersGI tumors represent a heterogeneous group of neoplasms concerning their natural history and molecular alterations harbored. Nevertheless, these tumors share very high incidence and mortality rates worldwide and patients’ poor prognosis. Therefore, the identification of specific biomarkers could increase the development of personalized medicine, in order to improve GI cancer management. In this sense, HMGA family members (HMGA1 and HMGA2) comprise
- Sodium Selenite Accentuates the Therapeutic Effect of Adriamycin Prodrug (PADM) against Gastric CancerSelenium has remained a controversial character in cancer research. While its antitumor effects have been widely demonstrated, further evidence is required to establish it as a robust treatment regime. Sodium selenite (SS), an inorganic selenium, reportedly affected the proliferation and redifferentiation of gastric cancer cells, but whether it could act as a complement to conventional chemotherapeutic drugs for combination therapy is uncertain.
- Comparison of Clinical Outcomes of Two-Level PELD and Foraminoplasty PELD for Highly Migrated Disc Herniations: A Comparative StudyObjective. The aim of this study is to compare the clinical outcomes of two-level percutaneous endoscopic lumbar discectomy (PELD) and foraminoplasty PELD in treating highly migrated lumbar disc herniations. Methods. Patients with highly migrated lumbar disc herniations were enrolled from May 2014 to June 2016. Low back pain and leg pain were evaluated by the Visual Analog Scale (VAS), and functional outcomes were assessed with the Oswestry Disab
- Optimized Parameters of Diffusion-Weighted MRI for Prediction of the Response to Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal CancerAim. To identify the optimal diffusion-weighted MRI-derived parameters for predicting the response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Methods. This prospective study enrolled 92 patients who underwent neoadjuvant chemoradiotherapy. Diffusion-weighted MRI sequences with two b-value combinations of b (0, 800) and b (0, 1000) were acquired before the start of neoadjuvant chemoradiotherapy and surgery. The pathologica
- Leucine Regulates the Exocrine Function in Pancreatic Tissue of Dairy Goats In VitroThis study aimed to investigate the effects of leucine (Leu) on the synthesis and secretion of digestive enzymes in cultured pancreatic tissue of dairy goats and on the signaling molecules. Fresh pancreatic tissue from dairy goats was cut into approximately 2 mm × 2 mm pieces and incubated in oxygenated Krebs-Ringer bicarbonate buffer containing 0 (the control), 0.40, 0.80, or 1.60 mM Leu at 39°C in a CO2 incubator for 180 min. The results showed
- Glycemic and Insulinemic Responses of Vegetables and Beans Powders Supplemented Chapattis in Healthy Humans: A Randomized, Crossover TrialVegetables and beans are nutrient-dense foods with innate potential to mediate diabetes in a variety of cultures. The present study aims at evaluating vegetables and beans for assessing their glycemic index and response in raising glucose levels in human model. Powdered formulations of vegetables and beans were designed to modulate glycemic response of carbohydrate-rich staples. A randomized, crossover trial was conducted in healthy young adults
- Biological Influence of Nonswelling Microgels on Cartilage Induction of Mouse Adipose-Derived Stem CellsIn cartilage tissue engineering, the target cells’ functional performance depends on the biomaterials. However, it is difficult to develop an appropriate scaffold to differentiate mouse adipose-derived stem cells (mADSCs) into chondrocyte despite an increasing number of studies on biological scaffold materials. The purpose of this study was to create a novel scaffold for mADSC culture and chondrogenic differentiation with a new series of microgel
- GYY4137 Attenuates Sodium Deoxycholate-Induced Intestinal Barrier Injury Both In Vitro and In VivoObjectives. Substantial studies have demonstrated that an elevated concentration of deoxycholic acid (DCA) in the colonic lumen may play a critical role in the pathogenesis of intestinal barrier dysfunction and inflammatory bowel disease (IBD). The purpose of this study was to investigate the protective effects of GYY4137, as a novel and synthetic H2S donor, on the injury of intestinal barrier induced by sodium deoxycholate (SDC) both in vivo and
- The Value of Contrast-Enhanced Ultrasound Classification in Diagnosis of Pancreatic Cystic LesionsObjective. To compare the consistency of contrast-enhanced ultrasound (CEUS) classification results with magnetic resonance imaging (MRI) and to investigate the diagnostic value of CEUS classification in pancreatic cystic lesions. Methods. 84 cases of pancreatic cystic lesions were enrolled in this study. According to the CEUS classification methods of previous study in our center, all the lesions were classified into four types: type I, unilocul
- Rare Mutations in AHDC1 in Patients with Obstructive Sleep ApneaObjectives. Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han individuals with OSA. Patients and Methods. Three hundred and seventy-five patients with OSA and one hundred and nine control in
Κυριακή 13 Οκτωβρίου 2019
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