Impacts of sex and the estrous cycle on associations between post-fear conditioning sleep and fear memory recall

Publication date: Available online 5 October 2019Source: Behavioural Brain ResearchAuthor(s): Ihori Kobayashi, Eva PolstonAbstractWomen are at greater risk than men for developing posttraumatic stress disorder (PTSD) after trauma exposure. Sleep, especially rapid-eye-movement sleep (REMS), has been considered a contributing factor to the development of PTSD symptoms through its effects on the processing of emotional memories. However, it remains unknown if sex and sex hormones play a role in the...

Behavioural Brain Research

Sun Oct 06, 2019 16:26

Effects of monoamine depletion on the ketamine-induced locomotor activity of preweanling, adolescent, and adult rats: sex and age differences

Publication date: Available online 5 October 2019Source: Behavioural Brain ResearchAuthor(s): Cynthia A. Crawford, Andrea E. Moran, Timothy J. Baum, Matthew G. Apodaca, Nazaret R. Montejano, Ginny I. Park, Vanessa Gomez, Sanders A. McDougallAbstractKetamine significantly increases the locomotor activity of rodents, however this effect varies according to the sex and age of the animal being tested. To determine the role monoamine systems play in ketamine’s locomotor activating effects: (a) male and...

Behavioural Brain Research

Sun Oct 06, 2019 16:26

Ketamine Sensitization: Influence of Dose, Environment, Social Isolation and Treatment Interval

Publication date: Available online 5 October 2019Source: Behavioural Brain ResearchAuthor(s): Keith A. Trujillo, Colleen Y. HellerAbstractKetamine is a dissociative anesthetic first developed in the 1960s but is increasingly used at subanesthetic doses for both clinical and non-clinical purposes. There is evidence from human recreational users of compulsive use and addiction. Sensitization is an increase in an effect of a drug with repeated use that is thought to be important in the development of...

Behavioural Brain Research

Sun Oct 06, 2019 16:26