Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. Gastroenterology. 2020 Jul 24;: Authors: DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM Abstract BACKGROUND...
Squamous Odontogenic Tumor: Review of the Literature and Report of a New Case. J Oral Maxillofac Surg. 2020 Jul 01;: Authors: Upadhyaya JD, Banasser A, Cohen DM, Kashtwari D, Bhattacharyya I, Islam MN Abstract PURPOSE: Squamous odontogenic tumor (SOT) is a rare, benign, locally infiltrative odontogenic tumor of the gnathic bones. It is composed of islands of bland, well-differentiated squamous epithelium of varying shape and size. Because of...
Related Articles A Rare Case of Invasive Melanoma Likely Arising from Passenger Melanocytes of a Basal Cell Carcinoma. J Cutan Pathol. 2020 Jul 27;: Authors: Paladichuk H, Talbott B Abstract Neoplasms consisting of different cell lineages within a single skin specimen are rare yet well-documented in the literature. However, to-date there appears to be no report of invasive melanoma arising directly from the passenger melanocytes of a basal cell...
Related Articles Multiplex melanoma families are enriched for polygenic risk. Hum Mol Genet. 2020 Jul 27;: Authors: Law MH, Aoude LG, Duffy DL, Long GV, Johansson PA, Pritchard AL, Khosrotehrani K, Mann GJ, Montgomery GW, Iles MM, Cust AE, Palmer JM, Melanoma GWAS Consortium, Shannon KF, Spillane AJ, Stretch JR, Thompson JF, Saw RPM, Scolyer RA, Martin NG, Hayward NK, MacGregor S Abstract Cancers, including cutaneous melanoma, can cluster in...
Related Articles An intrathoracic schwannoma case in 18F-FDG PET/CT scan. Hell J Nucl Med. 2020 Jul 27;: Authors: Gültekin A, AydoÄmuÅ Ã, ArifoÄlu H, Bir F, Yaylalı O Abstract Positron emission tomography /CT images showed a moderately increased 18F-FDG uptake in the mass of left lung lower lobe superior segment (SUVmax: 2.71). No pathological 18F-FDG involvement was detected in another region of the whole body scan. The patient underwent...
Related Articles Lymphoscintigraphy In a Case of Recurrent Chylopericardium. Asia Ocean J Nucl Med Biol. 2020;8(2):157-159 Authors: Kalimuthu LM, Saini VK, Pradhan PK Abstract Chylopericardium is an uncommon and benign condition in which triglyceride-containing chylous fluid collects in the pericardial cavity at high concentrations. Usually, chylopericardium occurs due to congenital malformation of lymphatic vessels or secondary to any trauma,...
Related Articles ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4. Front Cell Dev Biol. 2020;8:553 Authors: Sun X, Yu W, Li L, Sun Y Abstract ADNP (Activity Dependent Neuroprotective Protein) is proposed as a neuroprotective protein whose aberrant expression has been frequently linked to rare neural developmental disorders and cancers, including the recently described neurodevelopmental Helsmoortel-Van...
Related Articles A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection. Ann Med Surg (Lond). 2020 Sep;57:62-65 Authors: Sohail AA, Ayub B, Abbas SA, Sheikh SA, Qureshi TA, Usman M, Diwan A Abstract Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction...
Related Articles Primary retroperitoneal neuroendocrine tumor with nonspecific presentation: A case report. Radiol Case Rep. 2020 Sep;15(9):1663-1668 Authors: Taei THA, Mail SAA, Thinayyan AHA Abstract Primary retroperitoneal tumors are a rare entity of human neoplasms, with primary retroperitoneal neuroendocrine tumors being even more rare. They are usually metastatic and rarely seen as a primary tumor. We report a case of primary retroperitoneal...
Related Articles Pseudomyxoma Peritonei Originating from Transverse Colon Mucinous Adenocarcinoma: A Case Report and Literature Review. Gastroenterol Res Pract. 2020;2020:5826214 Authors: Gong Y, Wang X, Zhu Z Abstract Background: Pseudomyxoma peritonei (PMP) is a rare neoplasm involving the peritoneum. Most PMPs are low-grade appendicular mucinous neoplasms (LAMNs). There have been no reports of PMP originating from a transverse colonic mucinous...
Related Articles Rare Germline DICER1 Variants in Pediatric Patients With Cushing's Disease: What Is Their Role? Front Endocrinol (Lausanne). 2020;11:433 Authors: MartÃnez de LaPiscina I, Hernández-RamÃrez LC, Portillo N, Gómez-Gila AL, Urrutia I, MartÃnez-Salazar R, GarcÃa-Castaño A, Aguayo A, Rica I, Gaztambide S, Faucz FR, Keil MF, Lodish MB, Quezado M, Pankratz N, Chittiboina P, Lane J, Kay DM, Mills JL, Castaño L, Stratakis CA Abstract ...
Related Articles Spinal Intrathecal Actinomycosis Causes Multisegmental Root Failure: A Case Report. Front Neurol. 2020;11:621 Authors: Wang Y, Ren X, Shen D, Mao C, Wang H, Peng B, Gao J, Cui L Abstract Actinomycosis is a slowly progressing infection caused by Actinomyces species, which consists of filamentous gram-positive bacteria. Intraspinal actinomycosis is very rare and most of the previous cases presented with epidural lesions. Only...
Related Articles Abscopal effect of radiation therapy after nivolumab monotherapy in a patient with oral mucosal melanoma: A case report. Oral Oncol. 2020 Jul 23;:104919 Authors: Igarashi H, Fukuda M, Konno Y, Takano H Abstract The Abscopal effect is a rare phenomenon whereby tumors outside of the irradiated field regress due to systemic antitumor effects of localized radiotherapy. In patients with oral mucosal melanoma, only one instance of...
Related Articles Microsurgical Resection of Cervical Intradural Juxtamedullary Solitary Fibrous Tumor: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Jul 25;: Authors: Perrini P, Di Carlo DT, Montemurro N, Benedetto N, Ortenzi V, Naccarato AG Abstract Solitary fibrous tumors (SFTs) are uncommon mesenchymal lesions originally described as pleura-based neoplasms. Intradural juxtamedullary SFTs are rare, hard, and scarcely vascularized...
Related Articles The effect of chemotherapy on survival in patients with nonmetastatic male breast cancer: A population-based observational study. Cancer. 2020 Aug 15;126 Suppl 16:3830-3836 Authors: Pan H, Zhang K, Wang M, Ling L, Wang S, Zhou W Abstract BACKGROUND: Male breast cancer is a rare malignant disease, accounting for <1% of all breast cancers. The treatment of male breast cancer is mainly extrapolated from the enormous literature...
Related Articles [Monitoring of immunotherapy : Possibilities and limitations]. Radiologe. 2020 Jul 24;: Authors: Schneider H, Illert AL, Bamberg F, Eisenblätter M Abstract BACKGROUND: Cancer immunotherapies play an increasing role in the treatment of advanced cancer. In a subset of patients, atypical response patterns and unconventional adverse events make diagnostic evaluation challenging for radiologists. OBJECTIVES: In this article,...
Related Articles Circulating Tumor Cell Detection Technologies and Clinical Utility: Challenges and Opportunities. Cancers (Basel). 2020 Jul 17;12(7): Authors: Habli Z, AlChamaa W, Saab R, Kadara H, Khraiche ML Abstract The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate from tumors into the bloodstream and are believed...
Related Articles The Role of Palliative Radiotherapy in the Treatment of Spinal Bone Metastases from Head and Neck Tumors-A Multicenter Analysis of a Rare Event. Cancers (Basel). 2020 Jul 18;12(7): Authors: Bostel T, Rühle A, Rackwitz T, Mayer A, Klodt T, Oebel L, Förster R, Schlampp I, Wollschläger D, Rief H, Sprave T, Debus J, Grosu AL, Schmidberger H, Akbaba S, Nicolay NH Abstract This retrospective multi-center analysis aimed to assess...
Systemic Treatment Selection for Patients with Advanced Pancreatic Neuroendocrine Tumours (PanNETs).
Related Articles Systemic Treatment Selection for Patients with Advanced Pancreatic Neuroendocrine Tumours (PanNETs). Cancers (Basel). 2020 Jul 21;12(7): Authors: Megdanova-Chipeva VG, Lamarca A, Backen A, McNamara MG, Barriuso J, Sergieva S, Gocheva L, Mansoor W, Manoharan P, Valle JW Abstract Pancreatic neuroendocrine tumours (PanNETs) are rare diseases and a good example of how research is not only feasible, but also of crucial importance...
Related Articles Integration of Serum Metabolomics into Clinical Assessment to Improve Outcome Prediction of Metastatic Soft Tissue Sarcoma Patients Treated with Trabectedin. Cancers (Basel). 2020 Jul 21;12(7): Authors: Miolo G, Di Gregorio E, Saorin A, Lombardi D, Scalone S, Buonadonna A, Steffan A, Corona G Abstract Soft tissue sarcomas (STS) are a group of rare and heterogeneous cancers with few diagnostic or prognostic biomarkers. This metabolomics...
Related Articles High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype. Cancers (Basel). 2020 Jul 21;12(7): Authors: Machlowska J, Kapusta P, Baj J, Morsink FHM, WoÅkow P, Maciejewski R, Offerhaus GJA, Sitarz R Abstract BACKGROUND: Gastric cancer is the fourth most common cause of cancer-related death. Currently, it is broadly accepted that the molecular complexity and heterogeneity...
Related Articles The Role of Inflammation and Inflammasome in Myeloproliferative Disease. J Clin Med. 2020 Jul 22;9(8): Authors: Longhitano L, Li Volti G, Giallongo C, Spampinato M, Barbagallo I, Di Rosa M, Romano A, Avola R, Tibullo D, Palumbo GA Abstract Polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) are rare hematological conditions known as myeloproliferative neoplasms (MPNs). They are characterized...
Related Articles Biliary Drainage Before and After Liver Resection for Perihilar Cholangiocarcinoma. Am Surg. 2020 Jun;86(6):628-634 Authors: Enomoto LM, Dixon MEB, Burdette A, Gusani NJ Abstract Perihilar cholangiocarcinoma (PHC) is a rare tumor that requires surgical resection for a potential cure. The role of preoperative biliary drainage has long been debated, given its treatment of biliary sepsis and decompression of the future liver remnant...
Related Articles Responses of metastatic primary fallopian tube carcinoma to pembrolizumab and nab-paclitaxel: A case report. Medicine (Baltimore). 2020 Jul 10;99(28):e21203 Authors: Jiang J, Chen ZP, Zhu HP, Zhang YQ, Qian XL, Zhang M, Ni C, Zuo Y Abstract RATIONALE: Primary fallopian tube carcinoma (PFTC) is an extremely rare but invasive malignancy with a dismal prognosis. Very few data exist on the salvage treatment for patients with PFTC....
Related Articles Blue rubber bleb nevus syndrome with the complication of intussusception: A case report and literature review. Medicine (Baltimore). 2020 Jul 10;99(28):e21199 Authors: Hu Z, Lin X, Zhong J, He Q, Peng Q, Xiao J, Chen B, Zhang J Abstract RATIONALE: Blue rubber bleb nevus syndrome (BRBNS) is an extremely rare disorder characterized by multifocal venous malformations involving various organs such as the skin and gastrointestinal...
Related Articles Successful management of a pregnant woman with Kasabach-Merritt syndrome and preeclampsia: A case report. Medicine (Baltimore). 2020 Jul 10;99(28):e21198 Authors: Yang Y, Guo Z, Wang Z, Luo L, Chen Y Abstract INTRODUCTION: Kasabach-Merritt Syndrome (KMS) is an extremely rare disease in adults, which lead to consumptive coagulopathy characterized by severe hypofibrinogenemia and thrombocytopenia. PATIENT CONCERNS:: a 25-year-old...
Related Articles Central retinal artery occlusion combined with posterior ciliary artery occlusion after preoperative embolization of the middle meningeal artery for intracranial meningioma: A case report. Medicine (Baltimore). 2020 Jul 10;99(28):e21197 Authors: Feng KM, Liang CM, Pao SI Abstract RATIONALE: Preoperative embolization of brain tumors has been widely used to minimize hemorrhaging during surgery, but anastomosis between vessels...
Related Articles Reversible posterior leukoencephalopathy syndrome due to adrenal pheochromocytoma: A case report and literature review. Medicine (Baltimore). 2020 Jul 10;99(28):e20918 Authors: Han B, Li Y, Tang M, Wu S, Xu X Abstract RATIONALE: Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare neuropathic syndrome with typical clinical and radiological features. There are large amounts of risk factors resulting in RPLS, those...
Related Articles Pediatric cystic lymphangioma of the retroperitoneum: A case report and review of the literature. Medicine (Baltimore). 2020 Jul 10;99(28):e20827 Authors: Poroes F, Petermann D, Andrejevic-Blant S, Labgaa I, Di Mare L Abstract RATIONALE: Cystic lymphangioma (CL) is a rare benign tumor resulting from a failure of the lymphatic system development. It may occur at any age but it is more frequent during childhood. Its clinical...
Related Articles Primary bladder mucosa-associated lymphoid tissue lymphoma: A case report and literature review. Medicine (Baltimore). 2020 Jul 10;99(28):e20825 Authors: Xu H, Chen Z, Shen B, Wei Z Abstract INTRODUCTION: Primary bladder mucosa-associated lymphoid tissue (MALT) lymphoma is a rare tumor. To date, the PubMed database contains only 39 English articles covering 63 cases of primary bladder MALT lymphoma. Herein, we report a case...
Related Articles Pharmacotherapy in Mast Cell Leukemia. Expert Opin Pharmacother. 2020 Jun;21(9):1059-1069 Authors: Laforgia M, Calabrò C, Scattone A, Laface C, Porcelli M, Gadaleta CD, Nardulli P, Ranieri G Abstract INTRODUCTION: Mast cell leukemia (MCL) is one of the most aggressive forms of Systemic Mastocytosis (SM), a complex family of rare diseases, for which standard therapies are very few. MCL represents only <1% cases of SM and...
Related Articles Long-term Evolution of Hepatocellular Adenomas at MRI Follow-up. Radiology. 2020 05;295(2):361-372 Authors: Vernuccio F, Ronot M, Dioguardi Burgio M, Cauchy F, Choudhury KR, Dokmak S, Soubrane O, Valla D, Zucman-Rossi J, Paradis V, Vilgrain V Abstract Background Hepatocellular adenomas (HCAs) are rare benign liver tumors. Guidelines recommend continued surveillance of patients diagnosed with HCAs, but these guidelines are mainly...
Related Articles Decidualized juvenile cystic adenomyoma mimicking a cornual pregnancy. Fertil Steril. 2020 02;113(2):463-465 Authors: Kiyak H, Seckin KD, Karakis L, Karacan T, Ozyurek ES, Resit Asoglu M Abstract OBJECTIVE: To demonstrate the laparoscopic excision technique of a juvenile cystic adenomyoma and show how the decidualization of ectopic endometrial tissue can lead to the misdiagnosis of a focus of ectopic pregnancy. DESIGN:...
Related Articles Application and Pitfalls of Immunohistochemistry in Diagnosis of Challenging Genitourinary Cases. Arch Pathol Lab Med. 2020 03;144(3):290-304 Authors: Ross J, Li G, Yang XJ Abstract CONTEXT.—: Immunohistochemistry (IHC) has become increasingly important in the evaluation of pathologic conditions in the genitourinary (GU) organs. In addition to careful evaluation of hematoxylin-eosin sections and generation of a differential...
Related Articles Vascular anomaly of the posterior circulation associated with intracranial lipoma-like lesion in the cerebral peduncle manifesting as oculomotor nerve palsy. J Clin Neurosci. 2020 Feb;72:463-466 Authors: Hirano Y, Miyawaki S, Yamada K, Shinya Y, Kin T, Amemiya S, Asakawa Y, Nakatomi H, Saito N Abstract Intracranial lipomas are rare and often located in the midline of the brain. Intracranial lipomas are often associated with...
Related Articles Histopathological features of condylar hyperplasia and condylar Osteochondroma: a comparison study. Orphanet J Rare Dis. 2019 12 16;14(1):293 Authors: Yu J, Yang T, Dai J, Wang X Abstract BACKGROUND: Both mandibular condylar hyperplasia and condylar osteochondroma can lead to maxillofacial skeletal asymmetry and malocclusion, although they exhibit different biological behavior. This study attempted to compare the histological...
Related Articles BILATERAL AVASCULAR NECROSIS OF SACRAL LATERAL MASSES AFTER A COMPLETE RADIOLOGICAL RESPONSE OF LOCALLY ADVANCED RECTAL CANCER TREATED WITH NEOADJUVANT CHEMORADIATION THERAPY. CASE REPORT. Probl Radiac Med Radiobiol. 2019 Dec;24:537-551 Authors: Zvirych VV, Makhmudov DE, Paliiy MI, Ashykhmin AV, Kolesnik OO Abstract We present a rare case report of a bilateral avascular necrosis of lateral sacral masses in a patient who developed...
Related Articles Cutaneous neurofibromas: patients' medical burden, current management and therapeutic expectations: results from an online European patient community survey. Orphanet J Rare Dis. 2019 12 04;14(1):286 Authors: Guiraud M, Bouroubi A, Beauchamp R, Bocquet A, Grégoire JM, Rauly-Lestienne I, Blanco I, Wolkenstein P, Schmitt AM Abstract BACKGROUND: Neurofibromatosis type 1 is an inherited condition with variable phenotypic expression...
Related Articles EGFR inhibition for metastasized cutaneous squamous cell carcinoma in dystrophic epidermolysis bullosa. Orphanet J Rare Dis. 2019 12 03;14(1):278 Authors: Diociaiuti A, Steinke H, Nyström A, Schwieger-Briel A, Meiss F, Pfannenberg C, Bruckner-Tuderman L, Ruf J, De Vito R, El Hachem M, Kiritsi D Abstract Dystrophic epidermolysis bullosa (DEB) is a hereditary skin fragility disorder, characterized by trauma-induced blistering...
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