IJMS, Vol. 21, Pages 5371: The Flavoproteome of the Model Plant Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21155371 Authors: Patrick Schall Lucas Marutschke Bernhard Grimm Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are essential cofactors for enzymes, which catalyze a broad spectrum of vital reactions. This paper intends to compile all potential FAD/FMN-binding proteins encoded by the genome of Arabidopsis thaliana....
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5367: Cationic Porphyrins as Effective Agents in Photodynamic Inactivation of Opportunistic Plumbing Pathogen Legionella pneumophila International Journal of Molecular Sciences doi: 10.3390/ijms21155367 Authors: Andrija Lesar Martina Mušković Gabrijela Begić Martin Lončarić Dijana Tomić Linšak Nela Malatesti Ivana Gobin Legionella pneumophila is an environmental bacterium, an opportunistic premise plumbing pathogen that causes the Legionnaires’...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5366: Umbilical Cord-Derived Mesenchymal Stem Cells are Able to Use bFGF Treatment and Represent a Superb Tool for Immunosuppressive Clinical Applications International Journal of Molecular Sciences doi: 10.3390/ijms21155366 Authors: Lenka Tesarova Klara Jaresova Pavel Simara Irena Koutna Mesenchymal stem cells (MSCs) have become a promising tool in cellular therapy for restoring immune system haemostasis; however, the success of clinical trials has been...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5368: Single Cell Transcriptome Analysis of Niemann–Pick Disease, Type C1 Cerebella International Journal of Molecular Sciences doi: 10.3390/ijms21155368 Authors: Cougnoux Yerger Fellmeth Serra-Vinardell Martin Navid Iben Wassif Cawley Porter Niemann–Pick disease, type C1 (NPC1) is a lysosomal disease characterized by endolysosomal storage of unesterified cholesterol and decreased cellular cholesterol bioavailability....
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5360: Stress Granule Formation Attenuates RACK1-Mediated Apoptotic Cell Death Induced by Morusin International Journal of Molecular Sciences doi: 10.3390/ijms21155360 Authors: Ye-Jin Park Dong Wook Choi Sang Woo Cho Jaeseok Han Siyoung Yang Cheol Yong Choi Stress granules are membraneless organelles composed of numerous components including ribonucleoproteins. The stress granules are characterized by a dynamic complex assembly in response to various...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5365: Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome International Journal of Molecular Sciences doi: 10.3390/ijms21155365 Authors: Mohammad Mehedi Hasan Janeli Viil Freddy Lättekivi James Ord Qurat Ul Ain Reshi Kersti Jääger Agne Velthut-Meikas Aneta Andronowska Ülle Jaakma Andres Salumets Alireza Fazeli While follicular fluid (FF) is well known...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5363: Changes in Proteome of Fibroblasts Isolated from Psoriatic Skin Lesions International Journal of Molecular Sciences doi: 10.3390/ijms21155363 Authors: Agnieszka Gęgotek Pedro Domingues Adam Wroński Elżbieta Skrzydlewska The dermal fibroblasts are in constant contact with the cells of the immune system and skin epidermis. Therefore, they are essential for the development of lesions in psoriasis. The aim of this study was to assess the changes in the...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5361: Development of Novel High-Resolution Size-Guided Turbidimetry-Enabled Particle Purification Liquid Chromatography (PPLC): Extracellular Vesicles and Membraneless Condensates in Focus International Journal of Molecular Sciences doi: 10.3390/ijms21155361 Authors: Hussein Kaddour Yuan Lyu Nadia Shouman Mahesh Mohan Chioma M. Okeoma Acellular particles (extracellular vesicles and membraneless condensates) have important research, drug discovery, and...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5362: Flavopereirine Inhibits Autophagy via the AKT/p38 MAPK Signaling Pathway in MDA-MB-231 Cells International Journal of Molecular Sciences doi: 10.3390/ijms21155362 Authors: Ming-Shan Chen Hsuan-Te Yeh Yi-Zhen Li Wen-Chun Lin Ying-Ray Lee Ya-Shih Tseng Shew-Meei Sheu Autophagy is a potential target for the treatment of triple negative breast cancer (TNBC). Because of a lack of targeted therapies for TNBC, it is vital to find optimal agents that...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5364: Evaluation of Mussel Shells Powder as Reinforcement for PLA-Based Biocomposites International Journal of Molecular Sciences doi: 10.3390/ijms21155364 Authors: Vito Gigante Patrizia Cinelli Maria Cristina Righetti Marco Sandroni Leonardo Tognotti Maurizia Seggiani Andrea Lazzeri The use of biopolyesters, as polymeric matrices, and natural fillers derived from wastes or by-products of food production to achieve biocomposites is nowadays a reality....
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5358: Role of the Ubiquitin Proteasome System in the Regulation of Blood Pressure: A Review International Journal of Molecular Sciences doi: 10.3390/ijms21155358 Authors: Osamu Yamazaki Daigoro Hirohama Kenichi Ishizawa Shigeru Shibata The kidney and the vasculature play crucial roles in regulating blood pressure. The ubiquitin proteasome system (UPS), a multienzyme process mediating covalent conjugation of the 76-amino acid polypeptide ubiquitin to a substrate...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5359: Small Extracellular Vesicles Isolated from Serum May Serve as Signal-Enhancers for the Monitoring of CNS Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21155359 Authors: Gabriella Dobra Matyas Bukva Zoltan Szabo Bella Bruszel Maria Harmati Edina Gyukity-Sebestyen Adrienn Jenei Monika Szucs Peter Horvath Tamas Biro Almos Klekner Krisztina Buzas Liquid biopsy-based methods to test biomarkers (e.g., serum proteins...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5356: Pseudomonas Aeruginosa Induced Cell Death in Acute Lung Injury and Acute Respiratory Distress Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms21155356 Authors: Rushikesh Deshpande Chunbin Zou Pseudomonas aeruginosa is an important opportunistic pathogen responsible for the cause of acute lung injury and acute respiratory distress syndrome. P. aeruginosa isthe leading species isolated from patients with nosocomial infection and is detected...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5357: Molecular Mechanism Contributing to Malnutrition and Sarcopenia in Patients with Liver Cirrhosis International Journal of Molecular Sciences doi: 10.3390/ijms21155357 Authors: Fatuma Meyer Karen Bannert Mats Wiese Susanne Esau Lea F. Sautter Luise Ehlers Ali A. Aghdassi Cornelia C. Metges Leif-A. Garbe Robert Jaster Markus M. Lerch Georg Lamprecht Luzia Valentini Liver cirrhosis is frequently accompanied by disease-related...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5355: Free Your Mind: Emotional Expressive Flexibility Moderates the Effect of Stress on Post-Traumatic Stress Disorder Symptoms International Journal of Molecular Sciences doi: 10.3390/ijms21155355 Authors: Einat Levy-Gigi Reut Donner George A. Bonanno Servicemen are exposed to high levels of stress as part of their daily routine, however, studies which tested the relationship between stress and clinical symptoms reached inconsistent results. The present study...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5354: Mapping the Transglycosylation Relevant Sites of Cold-Adapted β-d-Galactosidase from Arthrobacter sp. 32cB International Journal of Molecular Sciences doi: 10.3390/ijms21155354 Authors: Maria Rutkiewicz Marta Wanarska Anna Bujacz β-Galactosidase from Arthrobacter sp. 32cB (ArthβDG) is a cold-adapted enzyme able to catalyze hydrolysis of β-d-galactosides and transglycosylation reaction, where galactosyl moiety is being transferred...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5350: Expanding the Toolkit of Fluorescent Biosensors for Studying Mitogen Activated Protein Kinases in Plants International Journal of Molecular Sciences doi: 10.3390/ijms21155350 Authors: Kati Seitz Patrick J. Krysan Mitogen-activated protein kinases (MAPKs) are key regulators of numerous biological processes in plants. To better understand the mechanisms by which these kinases function, high resolution measurement of MAPK activation kinetics in different biological...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5352: Age-Related Memory Impairment Is Associated with Increased zif268 Protein Accumulation and Decreased Rpt6 Phosphorylation International Journal of Molecular Sciences doi: 10.3390/ijms21155352 Authors: Sydney Trask Brooke N. Dulka Fred J. Helmstetter Aging is associated with cognitive decline, including impairments in the ability to accurately form and recall memories. Some behavioral and brain changes associated with aging are evident as early as middle...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5349: Roles of Gangliosides in Hypothalamic Control of Energy Balance: New Insights International Journal of Molecular Sciences doi: 10.3390/ijms21155349 Authors: Kei-ichiro Inamori Jin-ichi Inokuchi Gangliosides are essential components of cell membranes and are involved in a variety of physiological processes, including cell growth, differentiation, and receptor-mediated signal transduction. They regulate functions of proteins in membrane microdomains, notably...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5353: MicroRNAs and Apoptosis in Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21155353 Authors: Hsiuying Wang Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to improve survival in CRC patients. Most anti-cancer therapies trigger apoptosis induction to eliminate malignant cells. However, de-regulated...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5351: NMR Characterization of Conformational Interconversions of Lys48-Linked Ubiquitin Chains International Journal of Molecular Sciences doi: 10.3390/ijms21155351 Authors: Methanee Hiranyakorn Saeko Yanaka Tadashi Satoh Thunchanok Wilasri Benchawan Jityuti Maho Yagi-Utsumi Koichi Kato Ubiquitin (Ub) molecules can be enzymatically connected through a specific isopeptide linkage, thereby mediating various cellular processes by binding to Ub-interacting...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5347: 2-Ketoglutarate-Generated In Vitro Enzymatic Biosystem Facilitates Fe(II)/2-Ketoglutarate-Dependent Dioxygenase-Mediated C–H Bond Oxidation for (2s,3r,4s)-4-Hydroxyisoleucine Synthesis International Journal of Molecular Sciences doi: 10.3390/ijms21155347 Authors: Xiao-Ran Jing Huan Liu Yao Nie Yan Xu Fe(II)/2-ketoglutarate-dependent dioxygenase (Fe(II)/2-KG DO)-mediated hydroxylation is a critical type of C–H bond functionalization for synthesizing...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5348: Selective Transport of Ag(I) through a Polymer Inclusion Membrane Containing a Calix[4]pyrrole Derivative from Nitrate Aqueous Solutions International Journal of Molecular Sciences doi: 10.3390/ijms21155348 Authors: Anna Nowik-Zajac Iwona Zawierucha Cezary Kozlowski Cellulose-triacetate-based polymer inclusion membranes (PIMs) with different concentrations of a calixpyrrole ester derivative as the membrane carrier were studied to determine their ability...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5345: The Roles of GRKs in Hemostasis and Thrombosis International Journal of Molecular Sciences doi: 10.3390/ijms21155345 Authors: Xi Chen Xuefei Zhao Matthew Cooper Peisong Ma Along with cancer, cardiovascular and cerebrovascular diseases remain by far the most common causes of death. Heart attacks and strokes are diseases in which platelets play a role, through activation on ruptured plaques and subsequent thrombus formation. Most platelet agonists activate...
Tue Jul 28, 2020 03:00
IJMS, Vol. 21, Pages 5346: Computational Studies of SARS-CoV-2 3CLpro: Insights from MD Simulations International Journal of Molecular Sciences doi: 10.3390/ijms21155346 Authors: Alessandro Grottesi Neva Bešker Andrew Emerson Candida Manelfi Andrea R. Beccari Francesco Frigerio Erik Lindahl Carmen Cerchia Carmine Talarico Given the enormous social and health impact of the pandemic triggered by severe acute respiratory syndrome 2 (SARS-CoV-2), the scientific community...
Tue Jul 28, 2020 03:00
IJNS, Vol. 6, Pages 58: Neonatal Screening on Tandem Mass Spectrometry as a Powerful Tool for the Reassessment of the Prevalence of Underestimated Diseases in Newborns and Their Family Members: A Focus on Short Chain Acyl-CoA Dehydrogenase Deficiency International Journal of Neonatal Screening doi: 10.3390/ijns6030058 Authors: MariaAnna Messina Alessia Arena Agata Fiumara Riccardo Iacobacci Concetta Meli Federica Raudino Early detection of disabling diseases, prior to...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2422: The Impact of Korean Medicine Treatment on the Incidence of Parkinson’s Disease in Patients with Inflammatory Bowel Disease: A Nationwide Population-Based Cohort Study in South Korea Journal of Clinical Medicine doi: 10.3390/jcm9082422 Authors: Noh Jang Kwon Cho Jung Moon Park Ko Kim Park We aimed to investigate the association between Korean medicine (KM) treatment and the risk of Parkinson’s Disease (PD) in patients...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2420: Dynamics of Platelet Counts in Major Trauma: The Impact of Haemostatic Resuscitation and Effects of Platelet Transfusion—A Sub-Study of the Randomized Controlled RETIC Trial Journal of Clinical Medicine doi: 10.3390/jcm9082420 Authors: Tauber Innerhofer von Langen Ströhle Fries Mittermayr Hell Oswald Innerhofer Although platelets play a central role in haemostasis, the dynamics of platelet counts during haemostatic resuscitation,...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2421: Patient Management in Aortic Stenosis: Towards Precision Medicine Through Protein Analysis, Imaging and Diagnostic Tests Journal of Clinical Medicine doi: 10.3390/jcm9082421 Authors: Mourino-Alvarez Martin-Rojas Corros-Vicente Corbacho-Alonso Padial Solis Barderas Aortic stenosis is the most frequent valvular disease in developed countries. It progresses from mild fibrocalcific leaflet changes to a more severe leaflet calcification at...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2418: Inflammatory Cells in Diffuse Large B Cell Lymphoma Journal of Clinical Medicine doi: 10.3390/jcm9082418 Authors: Tamma Ranieri Ingravallo Annese Oranger Gaudio Musto Specchia Ribatti Diffuse large B cell lymphoma (DLBCL), known as the most common non-Hodgkin lymphoma (NHL) subtype, is characterized by high clinical and biological heterogeneity. The tumor microenvironment (TME), in which the tumor cells reside, is crucial in the...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2419: MicroRNA-199b Deregulation Shows a Strong SET-Independent Prognostic Value in Early-Stage Colorectal Cancer Journal of Clinical Medicine doi: 10.3390/jcm9082419 Authors: Ion Cristóbal Jaime Rubio Blanca Torrejón Andrea Santos Cristina Caramés Melani Luque Marta Sanz-Álvarez Ruth Alonso Sandra Zazo Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas The endogenous PP2A inhibitor SET Nuclear Proto-Oncogene (SET) has been reported...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2412: Association between Hyperacusis and Tinnitus Journal of Clinical Medicine doi: 10.3390/jcm9082412 Authors: Christopher R. Cederroth Alessandra Lugo Niklas K. Edvall Andra Lazar Jose-Antonio Lopez-Escamez Jan Bulla Inger Uhlen Derek J. Hoare David M. Baguley Barbara Canlon Silvano Gallus Many individuals with tinnitus report experiencing hyperacusis (enhanced sensitivity to sounds). However, estimates of the association between hyperacusis...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2416: The Reality of Patient-Reported Outcomes of Health-Related Quality of Life in an Italian Cohort of Patients with Inflammatory Bowel Disease: Results from a Cross-Sectional Study Journal of Clinical Medicine doi: 10.3390/jcm9082416 Authors: Tiziana Larussa Danilo Flauti Ludovico Abenavoli Luigi Boccuto Evelina Suraci Raffaella Marasco Maria Imeneo Francesco Luzza Inflammatory bowel disease (IBD) has a negative impact on patients’...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2415: Association between Bone Metabolism and Vestibular Problems in the Modified Romberg Test: Data from the 2009–2010 Korean National Health and Nutrition Examination Survey Journal of Clinical Medicine doi: 10.3390/jcm9082415 Authors: So Young Kim Yang-Sun Cho Ji-Soo Kim Ja-Won Koo Osteoporosis contributes to the occurrence of falling and vestibular problems, particularly in elderly patients. This study aimed to investigate the association between bone...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2414: Impact of Women Obesity and Obesity Severity on Live Birth Rate after In Vitro Fertilization Journal of Clinical Medicine doi: 10.3390/jcm9082414 Authors: Brunet Aouinti Huguet Macioce Ranisavljevic Gala Avignon Mura Sultan Access to in vitro fertilization (IVF) for obese women varies across centers, and the impact of obesity on IVF outcomes is widely discussed. We assessed the impact of obesity and its severity on live birth...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2413: Epidemiological Features of the Bladder Neck Rest Position and Mobility Journal of Clinical Medicine doi: 10.3390/jcm9082413 Authors: Edyta Horosz Andrzej Pomian Aneta Zwierzchowska Wojciech Lisik Wojciech Majkusiak Paweł Tomasik Beata Rutkowska Joana Skalska Małgorzata Siemion Dominika Banasiuk Ewa Barcz The data concerning epidemiological determinants of the bladder neck (BN) mobility are scarce. The aim of the study was to determine...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2417: Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia/Lymphoma—Romanian Experience Journal of Clinical Medicine doi: 10.3390/jcm9082417 Authors: Alina D. Tanase Andrei Colita Oana G. Craciun Lavinia Lipan Zsofia Varady Laura Stefan Adela Ranete Sergiu Pasca Horia Bumbea Mihaela Andreescu Viola Popov Alexandru Bardas Daniel Coriu Anca Roxana Lupu Ciprian Tomuleasa Anca Colita Olivier Hermine Adult T-cell...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2411: Effect of Manual Therapy and Splint Therapy in People with Temporomandibular Disorders: A Preliminary Study Journal of Clinical Medicine doi: 10.3390/jcm9082411 Authors: Gemma Victoria Espí-López Anna Arnal-Gómez Alba Cuerda del Pino José Benavent-Corai Pilar Serra-Añó Marta Inglés Background: Isolated manual therapy techniques (MT) have shown beneficial effects in patients with temporomandibular disorders (TMD) but the effect of the combination...
Tue Jul 28, 2020 03:00
JCM, Vol. 9, Pages 2409: Main Fetal Predictors of Adverse Neonatal Outcomes in Pregnancies with Gestational Diabetes Mellitus Journal of Clinical Medicine doi: 10.3390/jcm9082409 Authors: Maria-Christina Antoniou Leah Gilbert Justine Gross Jean-Benoît Rossel Céline Julie Fischer Fumeaux Yvan Vial Jardena Jacqueline Puder The objectives of this study were to (a) assess the utility of fetal anthropometric variables to predict the most relevant adverse neonatal outcomes...
Tue Jul 28, 2020 03:00
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