Antibiotics, Vol. 9, Pages 416: Genetic Subtyping, Biofilm-Forming Ability and Biocide Susceptibility of Listeria monocytogenes Strains Isolated from a Ready-to-Eat Food Industry Antibiotics doi: 10.3390/antibiotics9070416 Authors: Joana Catarina Andrade António Lopes João Carlos de Sousa Alonso António Salvador Barreto Ana Rita Henriques Listeria monocytogenes is a foodborne pathogen of special concern for ready-to-eat food producers. The control of its presence is a critical...
Antibiotics, Vol. 9, Pages 415: Application of Bacteriophages to Control Vibrio alginolyticus Contamination in Oyster (Saccostrea glomerata) Larvae Antibiotics doi: 10.3390/antibiotics9070415 Authors: Le Southgate O’Connor Vu İpek Kurtböke Mortalities of bivalve larvae and spat linked with Vibrio spp. infection have been described in hatcheries since 1959, causing potential development of resistant bacteria. A reliable and sustainable solution to this problem is yet...
Antibiotics, Vol. 9, Pages 417: Isolation and Biological Properties of the Natural Flavonoids Pectolinarin and Pectolinarigenin—A Review Antibiotics doi: 10.3390/antibiotics9070417 Authors: Thamere Cheriet Balkeis Ben-Bachir Oumelkhir Thamri Ramdane Seghiri Ines Mancini Flavonoids are metabolites widely distributed in plants and commonly present in foods, such as fruits and vegetables. Pectolinarin, which belongs to the flavone subclass, has attracted considerable attention...
Antibiotics, Vol. 9, Pages 414: Bacteriophages and the One Health Approach to Combat Multidrug Resistance: Is This the Way? Antibiotics doi: 10.3390/antibiotics9070414 Authors: Mary Garvey Antimicrobial resistance necessitates action to reduce and eliminate infectious disease, ensure animal and human health, and combat emerging diseases. Species such as Acinetobacter baumanniii, vancomycin resistant Enterococcus, methicillin resistance Staphylococcus aureus, and Pseudomonas aeruginosa,...
Antibiotics, Vol. 9, Pages 413: Structural and Bioactivity Characterization of Filipin Derivatives from Engineered Streptomyces filipinensis Strains Reveals Clues for Reduced Haemolytic Action Antibiotics doi: 10.3390/antibiotics9070413 Authors: Eva G. Barreales Ángel Rumbero Tamara D. Payero Antonio de Pedro Ester Jambrina Jesús F. Aparicio The rise in the number of immunocompromised patients has led to an increased incidence of fungal infections, with high rates of morbidity...
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Antibodies, Vol. 9, Pages 33: From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry Antibodies doi: 10.3390/antib9030033 Authors: Darja Kanduc Aim: To define the autoimmune potential of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Methods: Experimentally validated epitopes cataloged at the Immune Epitope DataBase (IEDB) and present in SARS-CoV-2 were analyzed for peptide sharing with the human proteome. Results: Immunoreactive epitopes present...
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Antioxidants, Vol. 9, Pages 627: The Herbal Combination CPA4-1 Inhibits Changes in Retinal Capillaries and Reduction of Retinal Occludin in db/db Mice Antioxidants doi: 10.3390/antiox9070627 Authors: Kim Kim Kim Lee Jo Jung Lee Kim Increased formation of advanced glycation end products (AGEs) plays an important role in the development of diabetic retinopathy (DR) via blood-retinal barrier (BRB) dysfunction, and reduction of AGEs has been suggested as a therapeutic...
Antioxidants, Vol. 9, Pages 625: Antioxidant Activity in Supramolecular Carotenoid Complexes Favored by Nonpolar Environment and Disfavored by Hydrogen Bonding Antioxidants doi: 10.3390/antiox9070625 Authors: Yunlong Gao A. Ligia Focsan Lowell D. Kispert Carotenoids are well-known antioxidants. They have the ability to quench singlet oxygen and scavenge toxic free radicals preventing or reducing damage to living cells. We have found that carotenoids exhibit scavenging ability towards...
Antioxidants, Vol. 9, Pages 626: Erythronium japonicum Alleviates Inflammatory Pain by Inhibiting MAPK Activation and by Suppressing NF-κB Activation via ERK/Nrf2/HO-1 Signaling Pathway Antioxidants doi: 10.3390/antiox9070626 Authors: Joon Park Yun Tai Kim Microglial activation-mediated neuroinflammation influences the development of inflammatory pain. The aim of this study was to investigate the anti-inflammatory effects and mechanisms of aqueous Erythronium japonicum extract (EJE)...
Antioxidants, Vol. 9, Pages 623: Synthesis, In Vitro Antioxidant Properties and Distribution of a New Cyanothiophene-Based Phenolic Compound in Olive Oil-In-Water Emulsions Antioxidants doi: 10.3390/antiox9070623 Authors: Sonia Losada-Barreiro Matej Sova Janez Mravljak Luciano Saso Carlos Bravo-Díaz We synthesized and determined the antioxidant activity and distribution of a new cyanothiophene-based compound, N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-3,5-dihydroxybenzamide...
Antioxidants, Vol. 9, Pages 624: The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19 Antioxidants doi: 10.3390/antiox9070624 Authors: Francesca Silvagno Annamaria Vernone Gian Piero Pescarmona The novel COVID-19 pandemic is affecting the world’s population differently: mostly in the presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal cytokine storm and patients die from acute respiratory...
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Atmosphere, Vol. 11, Pages 754: Inversion Method of Regional Range-Dependent Surface Ducts with a Base Layer by Doppler Weather Radar Echoes Based on WRF Model Atmosphere doi: 10.3390/atmos11070754 Authors: Xiaozhou Liu Zhensen Wu Hongguang Wang Ground clutter caused by variations of atmospheric refraction environment can occur when the weather radar is observing precipitation systems, especially in the presence of a tropospheric duct. Therefore, the acquisition of duct parameters...
Atmosphere, Vol. 11, Pages 753: Climate Change and the Future Heat Stress Challenges among Smallholder Farmers in East Africa Atmosphere doi: 10.3390/atmos11070753 Authors: Yengoh Ardö Agricultural production in sub-Saharan Africa remains dependent on high inputs of human labor, a situation associated with direct exposure to daylight heat during critical periods of the agricultural calendar. We ask the question: how is the Wet-Bulb Globe Temperature (WBGT) going to be distributed...
Atmosphere, Vol. 11, Pages 752: Occurrence and Development of an Extreme Precipitation Event in the Ili Valley, Xinjiang, China and Analysis of Gravity Waves Atmosphere doi: 10.3390/atmos11070752 Authors: Huang Zhou Liu We used observational data and the results from a high-resolution numerical simulation model to analyze the occurrence and development of an extreme precipitation event in the Ili Valley, Xinjiang, China on 26 June 2015. We analyzed the horizontal wavelength,...
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Biology, Vol. 9, Pages 169: Comparison of the Photoautotrophic Growth Regimens of Chlorella sorokiniana in a Photobioreactor for Enhanced Biomass Productivity Biology doi: 10.3390/biology9070169 Authors: Elvira E. Ziganshina Svetlana S. Bulynina Ayrat M. Ziganshin Microalgae have a wide industrial potential because of their high metabolic diversity and plasticity. Selection of optimal cultivation methods is important to optimize multi-purpose microalgal biotechnologies. In this...
Biology, Vol. 9, Pages 170: Peptide Profiling and Biological Activities of 12-Month Ripened Parmigiano Reggiano Cheese Biology doi: 10.3390/biology9070170 Authors: Lisa Solieri Andrea Baldaccini Serena Martini Aldo Bianchi Valentina Pizzamiglio Davide Tagliazucchi Proteolysis degree, biological activities, and water-soluble peptide patterns were evaluated in 12 month-ripened Parmigiano Reggiano (PR) cheeses collected in different dairy farms and showing different salt...
Biology, Vol. 9, Pages 167: Impact of Cytokines and Phosphoproteins in Response to Chronic Joint Infection Biology doi: 10.3390/biology9070167 Authors: Nicole Prince Julia A. Penatzer Matthew J. Dietz Jonathan W. Boyd The early cellular response to infection has been investigated extensively, generating valuable information regarding the mediators of acute infection response. Various cytokines have been highlighted for their critical roles, and the actions of these cytokines...
Biology, Vol. 9, Pages 168: The Unknown Process Osseointegration Biology doi: 10.3390/biology9070168 Authors: Nansi López-Valverde Javier Flores-Fraile Antonio López-Valverde Although it was already described more than fifty years ago, there is yet no in-depth knowledge regarding the process of osseointegration as far as its mechanism of action is concerned. It could be one of the body’s ways of reacting to a foreign body, where the individual’s immune response...
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Biomedicines, Vol. 8, Pages 220: Inactivated Platelet Lysate Supports the Proliferation and Immunomodulant Characteristics of Mesenchymal Stromal Cells in GMP Culture Conditions Biomedicines doi: 10.3390/biomedicines8070220 Authors: Katia Mareschi Sara Castiglia Aloe Adamini Deborah Rustichelli Elena Marini Alessia Giovanna Santa Banche Niclot Massimiliano Bergallo Luciana Labanca Ivana Ferrero Franca Fagioli Mesenchymal stromal cells (MSCs) isolated from bone...
Biomedicines, Vol. 8, Pages 219: Thykamine Extracts from Spinach Reduce Acute Inflammation In Vivo and Downregulate Phlogogenic Functions of Human Blood Neutrophils In Vitro Biomedicines doi: 10.3390/biomedicines8070219 Authors: Vickie Beaupré Nathalie Boucher Isabel Desgagné-Penix The anti-inflammatory and antioxidant role of Thykamine, a botanical extract of thylakoides obtained from spinach leaves, has been investigated in animal and cellular models. The oxidative properties...
Biomedicines, Vol. 8, Pages 218: Changes in Circulating Extracellular Vesicles in Patients with ST-Elevation Myocardial Infarction and Potential Effects of Remote Ischemic Conditioning—A Randomized Controlled Trial Biomedicines doi: 10.3390/biomedicines8070218 Authors: Paul Haller Bernhard Jäger Edita Piackova Larissa Sztulman Claudia Wegberger Johann Wojta Mariann Gyöngyösi Attila Kiss Bruno Podesser Andreas Spittler Kurt Huber (1) Background: Extracellular...
Biomedicines, Vol. 8, Pages 217: Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors Biomedicines doi: 10.3390/biomedicines8070217 Authors: Isha Sharma Fei Deng Yashpal S. Kanwar Obesity is associated with perturbations in cellular energy homeostasis and consequential renal injury leading to chronic renal disease (CKD). Myo-inositol oxygenase (MIOX), a tubular enzyme, alters redox balance and subsequent tubular...
Biomedicines, Vol. 8, Pages 216: Proteome of Glioblastoma-Derived Exosomes as a Source of Biomarkers
Biomedicines, Vol. 8, Pages 216: Proteome of Glioblastoma-Derived Exosomes as a Source of Biomarkers Biomedicines doi: 10.3390/biomedicines8070216 Authors: Stanislav Naryzhny Andrey Volnitskiy Arthur Kopylov Elena Zorina Roman Kamyshinsky Viktor Bairamukov Luiza Garaeva Anatoly Shlikht Tatiana Shtam Extracellular vesicles (EV) are involved in important processes of glioblastoma multiforme (GBM), including malignancy and invasion. EV secreted by glioblastoma cells...
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Biomolecules, Vol. 10, Pages 1067: Residue and Dissipation Kinetics of Metsulfuron-Methyl Herbicide in Soil: A Field Assessment at an Oil Palm Plantation Biomolecules doi: 10.3390/biom10071067 Authors: Zainol Maznah B. Sahid Ismail Oii Kok Eng A field trial experiment was conducted to investigate the degradation of metsulfuron-methyl at two application dosages, 15 g a.i/ha and 30 g a.i/ha, at an oil palm plantation. Soil samples were collected at ‒1, 0, 1, 3, 7, 14, and 21 days...
Biomolecules, Vol. 10, Pages 1066: Proteomic and Bioinformatic Investigations of Heat-Treated Anisakis simplex Third-Stage Larvae Biomolecules doi: 10.3390/biom10071066 Authors: Maciej Kochanowski Mirosław Różycki Joanna Dąbrowska Aneta Bełcik Jacek Karamon Jacek Sroka Tomasz Cencek Anisakis simplex third-stage larvae are the main source of hidden allergens in marine fish products. Some Anisakis allergens are thermostable and, even highly processed, could cause hypersensitivity...
Biomolecules, Vol. 10, Pages 1065: The Role of Cardiac N-Methyl-D-Aspartate Receptors in Heart Conditioning—Effects on Heart Function and Oxidative Stress Biomolecules doi: 10.3390/biom10071065 Authors: Natalia Govoruskina Vladimir Jakovljevic Vladimir Zivkovic Isidora Milosavljevic Jovana Jeremic Jovana Bradic Sergey Bolevich Israpil Alisultanovich Omarov Dragan Djuric Katarina Radonjic Marijana Andjic Nevena Draginic Aleksandra Stojanovic Ivan Srejovic...
Biomolecules, Vol. 10, Pages 1061: Epigenetic Mechanisms of Resistance to Immune Checkpoint Inhibitors Biomolecules doi: 10.3390/biom10071061 Authors: Alexandre Perrier Audrey Didelot Pierre Laurent-Puig Hélène Blons Simon Garinet Immune checkpoint inhibitors (ICIs) have demonstrated to be highly efficient in treating solid tumors; however, many patients have limited benefits in terms of response and survival. This rapidly led to the investigation of combination therapies...
Biomolecules, Vol. 10, Pages 1063: Understanding the Biosynthetic Changes that Give Origin to the Distinctive Flavor of Sotol: Microbial Identification and Analysis of the Volatile Metabolites Profiles During Sotol (Dasylirion sp.) Must Fermentation Biomolecules doi: 10.3390/biom10071063 Authors: Francisco Javier Zavala-Díaz de la Serna Ricardo Contreras-López L. Paola Lerma-Torres Francisco Ruiz-Terán Beatriz A. Rocha-Gutiérrez Samuel B. Pérez-Vega Leslie R. Elías-Ogaz Ivan...
Biomolecules, Vol. 10, Pages 1062: Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility Biomolecules doi: 10.3390/biom10071062 Authors: Annalisa Pierro Emilien Etienne Guillaume Gerbaud Bruno Guigliarelli Stefano Ciurli Valérie Belle Barbara Zambelli Elisabetta Mileo UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea. This protein couples the hydrolysis...
Biomolecules, Vol. 10, Pages 1064: Over-Expression of Allograft Inflammatory Factor-1 (AIF-1) in Patients with Rheumatoid Arthritis Biomolecules doi: 10.3390/biom10071064 Authors: Katarzyna Piotrowska Sylwia Słuczanowska-Głabowska Mateusz Kurzawski Violetta Dziedziejko Patrycja Kopytko Edyta Paczkowska Dorota Rogińska Krzysztof Safranow Bogusław Machaliński Andrzej Pawlik Allograft inflammatory factor-1 (AIF-1) is a cytoplasmic protein that is encoded by the...
Biomolecules, Vol. 10, Pages 1060: Probing Structure and Function of Alkali Sensor IRR with Monoclonal Antibodies Biomolecules doi: 10.3390/biom10071060 Authors: Alexander S. Goryashchenko Andrey A. Mozhaev Oxana V. Serova Tatiana N. Erokhina Alexander N. Orsa Igor E. Deyev Alexander G. Petrenko To study the structure and function of the pH-regulated receptor tyrosine kinase insulin receptor-related receptor (IRR), а member of the insulin receptor family, we obtained...
Biomolecules, Vol. 10, Pages 1059: Inflammatory Breast Carcinoma: Elevated microRNA miR-181b-5p and Reduced miR-200b-3p, miR-200c-3p, and miR-203a-3p Expression as Potential Biomarkers with Diagnostic Value Biomolecules doi: 10.3390/biom10071059 Authors: Sarah Atef Fahim Mahmoud Salah Abdullah Nancy A. Espinoza-Sánchez Hebatallah Hassan Ayman M. Ibrahim Sarah Hamdy Ahmed George Shakir Mohamed A. Badawy Nadia I. Zakhary Burkhard Greve Mohamed El-Shinawi Martin...
Biomolecules, Vol. 10, Pages 1058: Machine Learning-Empowered FTIR Spectroscopy Serum Analysis Stratifies Healthy, Allergic, and SIT-Treated Mice and Humans Biomolecules doi: 10.3390/biom10071058 Authors: Elke Korb Murat Bağcıoğlu Erika Garner-Spitzer Ursula Wiedermann Monika Ehling-Schulz Irma Schabussova The unabated global increase of allergic patients leads to an unmet need for rapid and inexpensive tools for the diagnosis of allergies and for monitoring the outcome...
Biomolecules, Vol. 10, Pages 1057: The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse Biomolecules doi: 10.3390/biom10071057 Authors: Blandine Gausserès Junjun Liu Ewout Foppen Cécile Tourrel-Cuzin Ana Rodriguez Sanchez-Archidona Etienne Delangre Céline Cruciani-Guglielmacci Stéphanie Pons Uwe Maskos Bernard Thorens Christophe Magnan Jamileh Movassat Kamel Maouche Objective: Type 2 diabetes (T2D) occurs by deterioration...
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Brain Sciences, Vol. 10, Pages 455: Is Visual Creativity Embodied? Thinking Aloud While Performing the Creative Mental Synthesis Task Brain Sciences doi: 10.3390/brainsci10070455 Authors: Massimiliano Palmiero Laura Piccardi Over time, the view that creativity is embodied has emerged. In order to explore if visual creativity is supported by embodied mechanisms, the simulation approach was used as a framework of reference. The idea that visual creativity relies on mental representations...
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Cancers, Vol. 12, Pages 1929: Economic Evaluation of Population-Based BRCA1/BRCA2 Mutation Testing across Multiple Countries and Health Systems Cancers doi: 10.3390/cancers12071929 Authors: Ranjit Manchanda Li Sun Shreeya Patel Olivia Evans Janneke Wilschut Ana Carolina De Freitas Lopes Faiza Gaba Adam Brentnall Stephen Duffy Bin Cui Patricia Coelho De Soarez Zakir Husain John Hopper Zia Sadique Asima Mukhopadhyay Li Yang Johannes Berkhof Rosa...
Cancers, Vol. 12, Pages 1930: Circulating Tumor Cell Detection Technologies and Clinical Utility: Challenges and Opportunities Cancers doi: 10.3390/cancers12071930 Authors: Zeina Habli Walid AlChamaa Raya Saab Humam Kadara Massoud L. Khraiche The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate from tumors into the bloodstream and are believed to carry...
Cancers, Vol. 12, Pages 1928: Lectins in Cervical Screening Cancers doi: 10.3390/cancers12071928 Authors: Anita WW Lim André A. Neves Sarah Lam Shang Leen Pierre Lao-Sirieix Elizabeth Bird-Lieberman Naveena Singh Michael Sheaff Tony Hollingworth Kevin Brindle Peter Sasieni Cervical screening in low-resource settings remains an unmet need. Lectins are naturally occurring sugar-binding glycoproteins whose binding patterns change as cancer develops. Lectins discriminate...
Cancers, Vol. 12, Pages 1927: Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia Cancers doi: 10.3390/cancers12071927 Authors: Dhon Roméo Makanga Francesca Da Rin de Lorenzo Gaëlle David Catherine Willem Léa Dubreuil Nolwenn Legrand Thierry Guillaume Pierre Peterlin Amandine Lebourgeois Marie Christine Béné Alice Garnier Patrice Chevallier Ketevan Gendzekhadze Anne Cesbron Katia Gagne Béatrice Clemenceau Christelle...
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