Antibiotics, Vol. 9, Pages 455: From Ocean to Medicine: Pharmaceutical Applications of Metabolites from Marine Bacteria Antibiotics doi: 10.3390/antibiotics9080455 Authors: José Diogo Santos Inês Vitorino Fernando Reyes Francisca Vicente Olga Maria Lage Oceans cover seventy percent of the planet’s surface and besides being an immense reservoir of biological life, they serve as vital sources for human sustenance, tourism, transport and commerce. Yet, it is estimated...
Tue Jul 28, 2020 03:00
Antibiotics, Vol. 9, Pages 454: Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains Antibiotics doi: 10.3390/antibiotics9080454 Authors: Kim Park Noh Kim Yoo Kim Lee Jang It is difficult to identify new antifungal agents because of their eukaryotic nature. However, antimicrobial peptides can well differentiate among cell types owing to their variable amino acid content. This study aimed to investigate the antifungal effect of Hn-Mc,...
Tue Jul 28, 2020 03:00
Antibiotics, Vol. 9, Pages 453: Knowledge, Attitudes and Practices of Veterinarians Towards Antimicrobial Resistance and Stewardship in Nigeria Antibiotics doi: 10.3390/antibiotics9080453 Authors: Usman O. Adekanye Abel B. Ekiri Erika Galipó Abubakar Bala Muhammad Ana Mateus Roberto M. La Ragione Aliyu Wakawa Bryony Armson Erik Mijten Ruth Alafiatayo Gabriel Varga Alasdair J. C. Cook Antimicrobial resistance (AMR) is a global health concern and the inappropriate...
Tue Jul 28, 2020 03:00
Antibiotics, Vol. 9, Pages 456: Influence of Sulfonamide Contamination Derived from Veterinary Antibiotics on Plant Growth and Development Antibiotics doi: 10.3390/antibiotics9080456 Authors: Cheong Seo Chohra Yoon Choe Kantharaj Lee Veterinary antibiotics such as sulfonamides are widely used to increase feed efficiency and to protect against disease in livestock production. The sulfonamide antimicrobial mechanism involves the blocking of folate biosynthesis...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 677: Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential Antioxidants doi: 10.3390/antiox9080677 Authors: Antognoni Potente Mandrioli Angeloni Freschi Malaguti Hrelia Lugli Gennari Muzzi Tartarini Sweet cherries (Prunus avium L.) are highly appreciated fruits for their taste, color, nutritional value, and beneficial...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 675: Extraction of Antioxidants from Winemaking Byproducts: Effect of the Solvent on Phenolic Composition, Antioxidant and Anti-Cholinesterase Activities, and Electrochemical Behaviour Antioxidants doi: 10.3390/antiox9080675 Authors: María José Jara-Palacios Sandra Gonçalves Francisco J. Heredia Dolores Hernanz Anabela Romano Extraction solvent is a very important factor in the recovery of antioxidants from natural matrices. In this study, the...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 674: Theoretical Study of the Iron Complexes with Lipoic and Dihydrolipoic Acids: Exploring Secondary Antioxidant Activity Antioxidants doi: 10.3390/antiox9080674 Authors: Monreal-Corona Biddlecombe Ippolito Mora-Diez The thermodynamic stability of twenty-nine Fe(III) complexes with various deprotonated forms of lipoic (LA) and dihydrolipoic (DHLA) acids, with coordination numbers 4, 5 and 6, is studied at the M06(SMD)/6-31++G(d,p) level of theory...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 673: Conformational Equilibrium of NADPH–Cytochrome P450 Oxidoreductase Is Essential for Heme Oxygenase Reaction Antioxidants doi: 10.3390/antiox9080673 Authors: Masakazu Sugishima Junichi Taira Tatsuya Sagara Ryota Nakao Hideaki Sato Masato Noguchi Keiichi Fukuyama Ken Yamamoto Takuo Yasunaga Hiroshi Sakamoto Heme oxygenase (HO) catalyzes heme degradation using electrons supplied by NADPH–cytochrome P450 oxidoreductase...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 676: SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats Antioxidants doi: 10.3390/antiox9080676 Authors: Natalia A. Muraleva Natalia A. Stefanova Nataliya G. Kolosova Alzheimer’s disease (AD) is the most common type of dementia and is currently incurable, and mitogen-activated protein kinase (MAPK) p38 is implicated in the pathogenesis of AD. p38 MAPK inhibition is considered a promising...
Tue Jul 28, 2020 03:00
Antioxidants, Vol. 9, Pages 672: Melatonin—A Potent Therapeutic for Stroke and Stroke-Related Dementia Antioxidants doi: 10.3390/antiox9080672 Authors: Nadia Sadanandan Blaise Cozene Justin Cho You Jeong Park Madeline Saft Bella Gonzales-Portillo Cesar V. Borlongan Secreted by the pineal gland to regulate the circadian rhythm, melatonin is a powerful antioxidant that has been used to combat oxidative stress in the central nervous system. Melatonin-based therapies have...
Tue Jul 28, 2020 03:00
Arts, Vol. 9, Pages 84: Teresa Żarnower’s Mnemonic Desire for Defense of Warsaw: De-Montaging Photography Arts doi: 10.3390/arts9030084 Authors: Maria Anna Rogucka Teresa Żarnower (1897, Warsaw, Poland–1949, New York, United States), a Polish Constructivist artist of Jewish descent who was forced to emigrate abroad during World War II, became a dominant figure working for the Polish government in exile. She produced a series of photomontages for a book titled The Defense of...
Tue Jul 28, 2020 03:00
Atmosphere, Vol. 11, Pages 797: Microbiological Air Quality in a Highschool Gym Located in an Urban Area of Southern Poland—Preliminary Research Atmosphere doi: 10.3390/atmos11080797 Authors: Ewa Brągoszewska Izabela Biedroń Anna Mainka The benefits of regular exercise include improved physical and mental health. The school gym is a particular micro-environment where students perform intensive physical training. The question is if there is an increased risk of microbiological contamination....
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Atmosphere, Vol. 11, Pages 796: Identifying Characteristics of Wildfire Towers and Troughs Atmosphere doi: 10.3390/atmos11080796 Authors: Tirtha Banerjee Troy Holland Kurt Solander Marlin Holmes Rodman Linn Wildfire behavior is dictated by the complex interaction of numerous physical phenomena including dynamic ambient and fire-induced winds, heat transfer, aerodynamic drag on the wind by the fuel and combustion. These phenomena create complex feedback effects between the...
Tue Jul 28, 2020 03:00
Atmosphere, Vol. 11, Pages 795: Trends of UV Radiation in Antarctica Atmosphere doi: 10.3390/atmos11080795 Authors: Bernhard Stierle The success of the Montreal Protocol in curbing increases in harmful solar ultraviolet (UV) radiation at the Earth’s surface has recently been demonstrated. This study also provided evidence that the UV Index (UVI) measured by SUV-100 spectroradiometers at three Antarctic sites (South Pole, Arrival Heights, and Palmer Station) is now decreasing....
Tue Jul 28, 2020 03:00
Atmosphere, Vol. 11, Pages 794: Variation in Atmospheric Precipitation in Poland in the Years 2001–2018 Atmosphere doi: 10.3390/atmos11080794 Authors: Agnieszka Ziernicka-Wojtaszek Joanna Kopcińska Climate change scenarios are in agreement as to the direction of air temperature changes in global warming, although the magnitude of the warming depends on the scenario adopted. In contrast, projections of changes in precipitation totals in Poland are not clear and obvious. Analysis of...
Tue Jul 28, 2020 03:00
Biology, Vol. 9, Pages 193: Novel Biomarkers of Mastitis in Goat Milk Revealed by MALDI-TOF-MS-Based Peptide Profiling Biology doi: 10.3390/biology9080193 Authors: Monica Matuozzo Maria Stefania Spagnuolo Hany A. Hussein A. M. Gomaa Andrea Scaloni Chiara D'Ambrosio Mastitis is the most common infection of dairy goats impairing milk production and quality, which is usually recognized by mammary gland visual inspection and palpation. Subclinical forms of the disease are...
Tue Jul 28, 2020 03:00
Biology, Vol. 9, Pages 192: The Antiviral Properties of Cyclosporine. Focus on Coronavirus, Hepatitis C Virus, Influenza Virus, and Human Immunodeficiency Virus Infections Biology doi: 10.3390/biology9080192 Authors: Paulina Glowacka Lidia Rudnicka Olga Warszawik-Hendzel Mariusz Sikora Mohamad Goldust Patrycja Gajda Anna Stochmal Leszek Blicharz Adriana Rakowska Malgorzata Olszewska This review updates current knowledge regarding the risk of viral infections,...
Tue Jul 28, 2020 03:00
Biomedicines, Vol. 8, Pages 249: Novel Bradykinin-Potentiating Peptides and Three-Finger Toxins from Viper Venom: Combined NGS Venom Gland Transcriptomics and Quantitative Venom Proteomics of the Azemiops feae Viper Biomedicines doi: 10.3390/biomedicines8080249 Authors: Vladislav V. Babenko Rustam H. Ziganshin Christoph Weise Igor Dyachenko Elvira Shaykhutdinova Arkady N. Murashev Maxim Zhmak Vladislav Starkov Anh Ngoc Hoang Victor Tsetlin Yuri Utkin Feae’s...
Tue Jul 28, 2020 03:00
Biomedicines, Vol. 8, Pages 248: Extracellular Vesicles in Acute Stroke Diagnostics Biomedicines doi: 10.3390/biomedicines8080248 Authors: Katrine Tang Stenz Jesper Just Rolf Ankerlund Blauenfeldt Kim Ryun Drasbek There is a large unmet need for fast and reliable diagnostics in several diseases. One such disease is stroke, where the efficacy of modern reperfusion therapies is highly time-dependent. Diagnosis of stroke and treatment initiation should be performed as soon as possible,...
Tue Jul 28, 2020 03:00
Biomimetics, Vol. 5, Pages 36: Characterisation of the Interaction among Oil-In-Water Nanocapsules and Mucin Biomimetics doi: 10.3390/biomimetics5030036 Authors: Mar Collado-González Gurmeet Kaur Yadira González-Espinosa Rebecca Brooks Francisco M. Goycoolea Mucins are glycoproteins present in all mucosal surfaces and in secretions such as saliva. Mucins are involved in the mucoadhesion of nanodevices carrying bioactive molecules to their target sites in vivo. Oil-in-water...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1118: Phytochemical Targeting of STAT3 Orchestrated Lipid Metabolism in Therapy-Resistant Cancers Biomolecules doi: 10.3390/biom10081118 Authors: Carmen Tse Ashleigh Warner Rufaik Farook James G Cronin Lipids are critical for maintaining homeostasis and cellular metabolism. However, the dysregulation of lipid metabolism contributes to the pathogenesis of chronic inflammatory diseases and is a hallmark of several cancer types. Tumours exist in a microenvironment...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1117: Erratum: Majumder, S. et al. Zinc Oxide Nanoparticles Functionalized on Hydrogel Grafted Silk Fibroin Fabrics as Efficient Composite Dressing. Biomolecules 2020, 10, 710 Biomolecules doi: 10.3390/biom10081117 Authors: Sudip Majumder Ujjwal Ranjan Dahiya Sunny Yadav Pratibha Sharma Debashree Ghosh Gyandshwar K. Rao Varun Rawat Gaurav Kumar Anuj Kumar Chandra Mohan Srivastava The authors wish to make the following correction...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1115: Ancient Evolutionary Origin of Intrinsically Disordered Cancer Risk Regions Biomolecules doi: 10.3390/biom10081115 Authors: Mátyás Pajkos András Zeke Zsuzsanna Dosztányi Cancer is a heterogeneous genetic disease that alters the proper functioning of proteins involved in key regulatory processes such as cell cycle, DNA repair, survival, or apoptosis. Mutations often accumulate in hot-spots regions, highlighting critical functional modules within...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1116: Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1 Biomolecules doi: 10.3390/biom10081116 Authors: Sang-Heon Kim Jae-Woo Choi A-Ru Kim Sang-Choon Lee Moon-Young Yoon Avian influenza (AI) has severely affected the poultry industry worldwide and has caused the deaths of millions of birds. Highly pathogenic avian influenza virus is characterized by high mortality and the ability...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1114: Predicted Hotspot Residues Involved in Allosteric Signal Transmission in Pro-Apoptotic Peptide—Mcl1 Complexes Biomolecules doi: 10.3390/biom10081114 Authors: Parthiban Marimuthu Jamoliddin Razzokov Kalaimathy Singaravelu Annemie Bogaerts Mcl1 is a primary member of the Bcl–2 family—anti–apoptotic proteins (AAP)—that is overexpressed in several cancer pathologies. The apoptotic regulation is mediated through...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1113: Multiplex Soluble Biomarker Analysis from Pleural Effusion Biomolecules doi: 10.3390/biom10081113 Authors: Joman Javadi Katalin Dobra Anders Hjerpe Malignant pleural mesothelioma (MPM) is a highly aggressive and therapy resistant pleural malignancy that is caused by asbestos exposure. MPM is associated with poor prognosis and a short patient survival. The survival time is strongly influenced by the subtype of the tumor. Dyspnea and accumulation...
Tue Jul 28, 2020 03:00
Biomolecules, Vol. 10, Pages 1112: The Possibilities of Immunotherapy for Children with Primary Immunodeficiencies Associated with Cancers Biomolecules doi: 10.3390/biom10081112 Authors: Frederic Baleydier Fanette Bernard Marc Ansari Many primary immunodeficiencies (PIDs) are recognised as being associated with malignancies, particularly lymphoid malignancies, which represent the highest proportion of cancers occurring in conjunction with this underlying condition. When patients...
Tue Jul 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 489: The Role of Executive Functions in the Development of Empathy and Its Association with Externalizing Behaviors in Children with Neurodevelopmental Disorders and Other Psychiatric Comorbidities Brain Sciences doi: 10.3390/brainsci10080489 Authors: Chiara Cristofani Gianluca Sesso Paola Cristofani Pamela Fantozzi Emanuela Inguaggiato Pietro Muratori Antonio Narzisi Chiara Pfanner Simone Pisano Lisa Polidori Laura Ruglioni Elena...
Tue Jul 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 490: Body Representations in Children with Cerebral Palsy Brain Sciences doi: 10.3390/brainsci10080490 Authors: Antonella Di Vita Maria Cristina Cinelli Simona Raimo Maddalena Boccia Stefano Buratin Paola Gentili Maria Teresa Inzitari Teresa Iona Marco Iosa Daniela Morelli Francesco Ruggeri Giuseppina Russo Cecilia Guariglia Liana Palermo We constantly process top-down and bottom-up inputs concerning our own body that...
Tue Jul 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 488: Body Concept and Quality of Life in Patients with Idiopathic Dystonia Brain Sciences doi: 10.3390/brainsci10080488 Authors: Lejla Paracka Florian Wegner Claus Escher Martin Klietz Martina de Zwaan Mahmoud Abdallat Assel Saryyeva Joachim K. Krauss Patients with dystonia experience unusual postures and disfigurement. The aim of the study was to examine changes in the body concept in relation to quality of life and severity of dystonia....
Tue Jul 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 491: Actigraph-Measured Movement Correlates of Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in Young People with Tuberous Sclerosis Complex (TSC) with and without Intellectual Disability and Autism Spectrum Disorder (ASD) Brain Sciences doi: 10.3390/brainsci10080491 Authors: Tom Earnest Elizabeth Shephard Charlotte Tye Fiona McEwen Emma Woodhouse Holan Liang Fintan Sheerin Patrick F. Bolton Actigraphy, an objective measure...
Tue Jul 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 487: Transient Administration of Dopaminergic Precursor Causes Inheritable Overfeeding Behavior in Young Drosophila melanogaster Adults Brain Sciences doi: 10.3390/brainsci10080487 Authors: Thiago C. Moulin Federico Ferro Samuel Berkins Angela Hoyer Michael J. Williams Helgi B. Schiöth Imbalances in dopaminergic signaling during development have been indicated as part of the underlying neurobiology of several psychiatric illnesses, including...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2100: Clonal Hematopoiesis and Mutations of Myeloproliferative Neoplasms Cancers doi: 10.3390/cancers12082100 Authors: Lasse Kjær Myeloproliferative neoplasms (MPNs) are associated with the fewest number of mutations among known cancers. The mutations propelling these malignancies are phenotypic drivers providing an important implement for diagnosis, treatment response monitoring, and gaining insight into the disease biology. The phenotypic drivers of Philadelphia...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2099: Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines Cancers doi: 10.3390/cancers12082099 Authors: Reham Samir Hamida Gadah Albasher Mashael Mohammed Bin-Meferij Green nanoparticles represent a revolution in bionanotechnology, providing opportunities to fight life-threatening diseases, such as cancer, with less risk to the environment and to human health. Here, for the first...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2094: TIF1 Proteins in Genome Stability and Cancer Cancers doi: 10.3390/cancers12082094 Authors: Roisin M. McAvera Lisa J. Crawford Genomic instability is a hallmark of cancer cells which results in excessive DNA damage. To counteract this, cells have evolved a tightly regulated DNA damage response (DDR) to rapidly sense DNA damage and promote its repair whilst halting cell cycle progression. The DDR functions predominantly within the context of chromatin and...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2097: Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth Cancers doi: 10.3390/cancers12082097 Authors: Un-Ho Jin Sharon K. Michelhaugh Lisa A. Polin Rupesh Shrestha Sandeep Mittal Stephen Safe Background: The aryl hydrocarbon receptor (AhR) is expressed in gliomas and the highest staining is observed in glioblastomas. A recent study showed that the AhR exhibited tumor suppressor-like activity in established and patient-derived glioblastoma...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2098: DNA Damage-Inducing Anticancer Therapies: From Global to Precision Damage Cancers doi: 10.3390/cancers12082098 Authors: Thom G.A. Reuvers Roland Kanaar Julie Nonnekens DNA damage-inducing therapies are of tremendous value for cancer treatment and function by the direct or indirect formation of DNA lesions and subsequent inhibition of cellular proliferation. Of central importance in the cellular response to therapy-induced DNA damage is the DNA damage...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2096: Controlling TIME: How MNK Kinases Function to Shape Tumor Immunity Cancers doi: 10.3390/cancers12082096 Authors: Thao N.D. Pham Christina Spaulding Hidayatullah G. Munshi A number of studies have clearly established the oncogenic role for MAPK-interacting protein kinases (MNK) in human malignancies. Modulation of MNK activity affects translation of mRNAs involved in cancer development, progression, and resistance to therapies. As a result, there are...
Tue Jul 28, 2020 03:00
Cancers, Vol. 12, Pages 2095: TrkB Inhibits the BMP Signaling-Mediated Growth Inhibition of Cancer Cells Cancers doi: 10.3390/cancers12082095 Authors: Min Soo Kim Wook Jin We have previously observed that tropomyosin receptor kinase B (TrkB) induces breast cancer metastasis by activating both the Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) and phosphatidylinositol-3-Kinase (PI3K)/AKT signaling pathways and inhibiting runt-related transcription factor...
Tue Jul 28, 2020 03:00
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