IJERPH, Vol. 17, Pages 5136: Providing Sports Venues on Mainland China: Implications for Promoting Leisure-Time Physical Activity and National Fitness Policies International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145136 Authors: Kai Wang Xuhui Wang Leisure-time physical activity (LTPA) has been well documented as having substantial health benefits. The 2014 Chinese Fitness Survey Report stated that a lack of physical activity (PA) spaces is the most...
IJERPH, Vol. 17, Pages 5131: No-Touch Automated Disinfection System for Decontamination of Surfaces in Hospitals International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145131 Authors: Patryk Tarka Aneta Nitsch-Osuch Background: Hospital-acquired infections (HAIs) remain a common problem, which suggests that standard decontamination procedures are insufficient. Thus, new methods of decontamination are needed in hospitals. Methods: We assessed the effectiveness...
IJERPH, Vol. 17, Pages 5128: Impact of Exercises and Chair Massage on Musculoskeletal Pain of Young Musicians International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145128 Authors: Anna Cygańska Aleksandra Truszczyńska-Baszak Paweł Tomaszewski Due to the occurrence among musicians of musculoskeletal problems associated with playing a musical instrument, it is necessary to use prophylaxis. The aim of the study was to compare the effectiveness of two...
IJERPH, Vol. 17, Pages 5132: The Self-Management Experiences of Adolescents with Type 1 Diabetes: A Descriptive Phenomenology Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145132 Authors: Li-Chen Hung Chu-Yu Huang Fu-Sung Lo Su-Fen Cheng Many adolescents with type 1 diabetes experience challenges in achieving good glycemic control and have insufficient understanding in executing interventions for glycemic control. This study aimed...
IJERPH, Vol. 17, Pages 5130: Quality of Palliative and End-Of-Life Care in Hong Kong: Perspectives of Healthcare Providers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145130 Authors: Eliza Lai-Yi Wong Nicole Kiang Roger Yat-Nork Chung Janice Lau Patsy Yuen-Kwan Chau Samuel Yeung-Shan Wong Jean Woo Emily Ying-Yang Chan Eng-Kiong Yeoh Background: In response to population aging, there is a need for health systems to focus...
IJERPH, Vol. 17, Pages 5125: Injury Profiles in Korean Youth Soccer International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145125 Authors: Inje Lee Hee Seong Jeong Sae Yong Lee We aimed to analyze injury profiles and injury severity in Korean youth soccer players. Data on all injuries that occurred in U-15 youth soccer players during the 2019 season were collected from 681 players of 22 teams through a medical questionnaire. The questionnaire was...
IJERPH, Vol. 17, Pages 5129: Food-Borne Disease Prevention and Risk Assessment International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145129 Authors: Ewen Todd “Food-borne Disease Prevention and Risk Assessment” is a Special Issue of the International Journal of Environmental Research and Public Health on understanding how food-borne disease is still a global threat to health today and to be able to target strategies to reduce its prevalence...
IJERPH, Vol. 17, Pages 5126: Parental Factors Associated with Obesity in Korean Adolescents International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145126 Authors: Heun Keung Yoon Gwang Suk Kim Suhee Kim Parental characteristics can influence adolescent obesity. However, the influence of parental characteristics on obesity may differ depending on the adolescent’s sex. This study evaluated parental characteristics that were associated with...
IJERPH, Vol. 17, Pages 5127: Cancer Mortality Trends in Spain (2000–2016): Differences between Immigrant and Native Populations International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17145127 Authors: Adriana Oliva-Arocas Pamela Pereyra-Zamora José M. Copete Andreu Nolasco Spain’s population has changed thanks to recent immigration. Therefore, a new epidemiological and demographic profile has been generated in the country. This study aims...
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IJMS, Vol. 21, Pages 5038: Aggregation and Prion-Inducing Properties of the G-Protein Gamma Subunit Ste18 are Regulated by Membrane Association International Journal of Molecular Sciences doi: 10.3390/ijms21145038 Authors: Tatiana A. Chernova Zhen Yang Tatiana S. Karpova John R. Shanks Natalia Shcherbik Keith D. Wilkinson Yury O. Chernoff Yeast prions and mnemons are respectively transmissible and non-transmissible self-perpetuating protein assemblies, frequently based...
IJMS, Vol. 21, Pages 5027: ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21145027 Authors: Jesper Andreas Palshof Camilla Natasha Cederbye Estrid Vilma Solyom Høgdall Tim Svenstrup Poulsen Dorte Linnemann Sune Boris Nygaard Jan Stenvang Ib Jarle Christensen Benny Vittrup Jensen Per Pfeiffer Nils Brünner Mette...
IJMS, Vol. 21, Pages 5036: Hereditary Predisposition to Prostate Cancer: From Genetics to Clinical Implications International Journal of Molecular Sciences doi: 10.3390/ijms21145036 Authors: Andreia Brandão Paula Paulo Manuel R. Teixeira Prostate cancer (PrCa) ranks among the top five cancers for both incidence and mortality worldwide. A significant proportion of PrCa susceptibility has been attributed to inherited predisposition, with 10–20% of cases expected to occur...
IJMS, Vol. 21, Pages 5037: How Postural Muscle Senses Disuse? Early Signs and Signals International Journal of Molecular Sciences doi: 10.3390/ijms21145037 Authors: Boris S. Shenkman A mammalian soleus muscle along with other “axial” muscles ensures the stability of the body under the Earth's gravity. In rat experiments with hindlimb suspension, zero-gravity parabolic flights as well as in human dry immersion studies, a dramatic decrease in the electromyographic (EMG)...
IJMS, Vol. 21, Pages 5035: Seeding and Growth of β-Amyloid Aggregates Upon Interaction with Neuronal Cell Membranes International Journal of Molecular Sciences doi: 10.3390/ijms21145035 Authors: Álvaro Ruiz-Arias Jose M. Paredes Chiara Di Biase Juan M. Cuerva María D. Giron Rafael Salto Juan A. González-Vera Angel Orte In recent years, the prevalence of amyloid neurodegenerative diseases such as Alzheimer’s disease (AD) has significantly increased in developed...
IJMS, Vol. 21, Pages 5033: Two Clubroot-Resistance Genes, Rcr3 and Rcr9wa, Mapped in Brassica rapa Using Bulk Segregant RNA Sequencing International Journal of Molecular Sciences doi: 10.3390/ijms21145033 Authors: Md. Masud Karim Abdulsalam Dakouri Yan Zhang Qilin Chen Gary Peng Stephen E. Strelkov Bruce D. Gossen Fengqun Yu Genetic resistance is widely used to manage clubroot (Plasmodiophora brassicae) in brassica crops, but new pathotypes have recently been identified...
IJMS, Vol. 21, Pages 5032: Nutri-Epigenetics and Gut Microbiota: How Birth Care, Bonding and Breastfeeding Can Influence and Be Influenced? International Journal of Molecular Sciences doi: 10.3390/ijms21145032 Authors: Rosita Gabbianelli Laura Bordoni Sandra Morano Jean Calleja-Agius Joan G. Lalor Maternal lifestyle is an important factor in the programming of an infant’s epigenome, in particular when considered alongside the mode of birth and choice of feeding...
IJMS, Vol. 21, Pages 5034: The Latest Findings of PD-1/PD-L1 Inhibitor Application in Gynecologic Cancers International Journal of Molecular Sciences doi: 10.3390/ijms21145034 Authors: Omid Kooshkaki Afshin Derakhshani Hossein Safarpour Souzan Najafi Parviz Vahedi Oronzo Brunetti Mitra Torabi Parisa Lotfinejad Angelo Virgilio Paradiso Vito Racanelli Nicola Silvestris Behzad Baradaran Gynecologic cancers account for approximately 11% of the newly diagnosed...
IJMS, Vol. 21, Pages 5030: Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery is the Core International Journal of Molecular Sciences doi: 10.3390/ijms21145030 Authors: Elena Vacchi Alain Kaelin-Lang Giorgia Melli In neuronal cells, tau is a microtubule-associated protein placed in axons and alpha synuclein is enriched at presynaptic terminals. They display a propensity to form pathologic aggregates, which are considered the underlying...
IJMS, Vol. 21, Pages 5029: p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles International Journal of Molecular Sciences doi: 10.3390/ijms21145029 Authors: Sonia Emanuele Marianna Lauricella Antonella D’Anneo Daniela Carlisi Anna De Blasio Diana Di Liberto Michela Giuliano p62 is a versatile protein involved in the delicate balance between cell death and survival, which is fundamental for cell fate decision in the context of both cancer and neurodegenerative...
IJMS, Vol. 21, Pages 5023: Beyond the Genomic Mutation: Rethinking the Molecular Biomarkers of K-RAS Dependency in Pancreatic Cancers International Journal of Molecular Sciences doi: 10.3390/ijms21145023 Authors: Carla Mottini Luca Cardone Oncogenic v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (K-RAS) plays a key role in the development and maintenance of pancreatic ductal adenocarcinoma (PDAC). The targeting of K-RAS would be beneficial to treat tumors whose growth depends...
IJMS, Vol. 21, Pages 5028: Detection of a G-Quadruplex as a Regulatory Element in Thymidylate Synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins International Journal of Molecular Sciences doi: 10.3390/ijms21145028 Authors: Eva Aubets Alex J. Félix Miguel Garavís Laura Reyes Anna Aviñó Ramón Eritja Carlos J. Ciudad Véronique Noé Thymidylate synthase (TYMS) enzyme is an anti-cancer target given its role in DNA biosynthesis. TYMS inhibitors (e.g.,...
IJMS, Vol. 21, Pages 5031: Transcriptome Analysis Provides Insights into Grain Filling in Foxtail Millet (Setaria italica L.) International Journal of Molecular Sciences doi: 10.3390/ijms21145031 Authors: Tao Wang Hui Song Pengtao Li Yangyang Wei Nan Hu Zhenwen Chen Weiqi Wang Jinrong Liu Baohong Zhang Renhai Peng Grain filling is an importantly developmental process which is associated with the yield and quality of foxtail millet (Setaria italic L.). However,...
IJMS, Vol. 21, Pages 5026: The Role of Herpes Simplex Virus Type 1 Infection in Demyelination of the Central Nervous System International Journal of Molecular Sciences doi: 10.3390/ijms21145026 Authors: Raquel Bello-Morales Sabina Andreu José Antonio López-Guerrero Herpes simplex type 1 (HSV-1) is a neurotropic virus that infects the peripheral and central nervous systems. After primary infection in epithelial cells, HSV-1 spreads retrogradely to the peripheral nervous system (PNS),...
IJMS, Vol. 21, Pages 5017: The Role of IgG4 in the Fine Tuning of Tolerance in IgE-Mediated Allergy and Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21145017 Authors: Rodolfo Bianchini Sophia N. Karagiannis Galateja Jordakieva Erika Jensen-Jarolim Among the four immunoglobulin G (IgG) subclasses, IgG4 is the least represented in serum of a healthy human and it is considered an “odd” antibody. The IgG4 antibody has unique structural...
IJMS, Vol. 21, Pages 5025: Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms21145025 Authors: Leclair Tardif Paris Galibert Corre : BRAF and MEK inhibitors (BRAFi and MEKi) are the standard of care for the treatment of metastatic melanoma in patients with BRAFV600E mutations, greatly improving progression-free survival. However, the acquisition of resistance...
IJMS, Vol. 21, Pages 5016: New Opportunity to Formulate Intranasal Vaccines and Drug Delivery Systems Based on Chitosan International Journal of Molecular Sciences doi: 10.3390/ijms21145016 Authors: Roxana Popescu Mihaela Violeta Ghica Cristina-Elena Dinu-Pîrvu Valentina Anuța Dumitru Lupuliasa Lăcrămioara Popa In an attempt to develop drug delivery systems that bypass the blood–brain barrier (BBB) and prevent liver and intestinal degradation, it was concluded...
IJMS, Vol. 21, Pages 5022: Role of RNA Oxidation in Neurodegenerative Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21145022 Authors: Ziqian Liu Xiatian Chen Zhe Li Wei Ye Hongyan Ding Peifeng Li Lynn Htet Htet Aung In the history of nucleic acid research, DNA has always been the main research focus. After the sketch of the human genome was completed in 2000, RNA has been started to gain more attention due to its abundancies in the cell and its...
IJMS, Vol. 21, Pages 5020: Human Papillomavirus 16-Transgenic Mice as a Model to Study Cancer-Associated Cachexia International Journal of Molecular Sciences doi: 10.3390/ijms21145020 Authors: Sara Peixoto da Silva Joana M. O. Santos Verónica F. Mestre Beatriz Medeiros-Fonseca Paula A. Oliveira Margarida M. S. M. Bastos Rui M. Gil da Costa Rui Medeiros Cancer cachexia is a multifactorial syndrome characterized by general inflammation, weight loss and muscle wasting,...
IJMS, Vol. 21, Pages 5021: Differential Effects of MS Therapeutics on B Cells—Implications for Their Use and Failure in AQP4-Positive NMOSD Patients International Journal of Molecular Sciences doi: 10.3390/ijms21145021 Authors: Jan Traub Silke Häusser-Kinzel Martin Weber B cells are considered major contributors to multiple sclerosis (MS) pathophysiology. While lately approved disease-modifying drugs like ocrelizumab deplete B cells directly, most MS medications were not primarily...
IJMS, Vol. 21, Pages 5024: NMR Spectroscopic Studies of Cation Dynamics in Symmetrically-Substituted Imidazolium-Based Ionic Liquid Crystals International Journal of Molecular Sciences doi: 10.3390/ijms21145024 Authors: Debashis Majhi Andrei V. Komolkin Sergey V. Dvinskikh Ionic liquid crystals (ILCs) present a new class of non-molecular soft materials with a unique combination of high ionic conductivity and anisotropy of physicochemical properties. Symmetrically-substituted long-chain...
IJMS, Vol. 21, Pages 5018: Characterization of the UDP-glycosyltransferase UGT72 Family in Poplar and Identification of Genes Involved in the Glycosylation of Monolignols International Journal of Molecular Sciences doi: 10.3390/ijms21145018 Authors: Nathanael Speeckaert Nassirou Mahamadou Adamou Hadjara Amadou Hassane Fabien Baldacci-Cresp Adeline Mol Geert Goeminne Wout Boerjan Pierre Duez Simon Hawkins Godfrey Neutelings Thomas Hoffmann Wilfried Schwab Mondher...
IJMS, Vol. 21, Pages 5014: Exploring Drug Treatment Patterns Based on the Action of Drug and Multilayer Network Model International Journal of Molecular Sciences doi: 10.3390/ijms21145014 Authors: Liang Yu Yayong Shi Quan Zou Shuhang Wang Liping Zheng Lin Gao Some drugs can be used to treat multiple diseases, suggesting potential patterns in drug treatment. Determination of drug treatment patterns can improve our understanding of the mechanisms of drug action, enabling...
IJMS, Vol. 21, Pages 5019: Resolvin D1 and D2 Inhibit Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Ion Channel Activation on Sensory Neurons via Lipid Raft Modification International Journal of Molecular Sciences doi: 10.3390/ijms21145019 Authors: Maja Payrits Ádám Horváth Tünde Biró-Sütő János Erostyák Géza Makkai Éva Sághy Krisztina Pohóczky Angéla Kecskés Miklós Kecskés János Szolcsányi Zsuzsanna Helyes Éva Szőke Transient Receptor Potential...
IJMS, Vol. 21, Pages 5015: An Intact Cell Bioluminescence-Based Assay for the Simple and Rapid Diagnosis of Urinary Tract Infection International Journal of Molecular Sciences doi: 10.3390/ijms21145015 Authors: Sherwin Reyes Nga Le Mary Denneth Fuentes Jonathan Upegui Emre Dikici David Broyles Edward Quinto Sylvia Daunert Sapna K. Deo Urinary tract infection (UTI) is one of the most common infections, accounting for a substantial portion of outpatient hospital...
IJMS, Vol. 21, Pages 5013: The Regulatory Role of T Cell Responses in Cardiac Remodeling Following Myocardial Infarction International Journal of Molecular Sciences doi: 10.3390/ijms21145013 Authors: Tabito Kino Mohsin Khan Sadia Mohsin Ischemic injury to the heart causes cardiomyocyte and supportive tissue death that result in adverse remodeling and formation of scar tissue at the site of injury. The dying cardiac tissue secretes a variety of cytokines and chemokines that trigger...
IJMS, Vol. 21, Pages 5012: The Transcription Factor SCX is a Potential Serum Biomarker of Fibrotic Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21145012 Authors: Miguel Ramírez-Aragón Fernando Hernández-Sánchez Tatiana S. Rodríguez-Reyna Ivette Buendía-Roldán Gael Güitrón-Castillo Carlos A. Núñez-Alvarez Diego F. Hernández-Ramírez Sergio A. Benavides-Suárez Alexia Esquinca-González Ana Lilia Torres-Machorro Criselda Mendoza-Milla Fibrosing...
IJMS, Vol. 21, Pages 5010: Egg Allergy: Diagnosis and Immunotherapy International Journal of Molecular Sciences doi: 10.3390/ijms21145010 Authors: Dulashi Withanage Dona Cenk Suphioglu Hypersensitivity or an allergy to chicken egg proteins is a predominant symptomatic condition affecting 1 in 20 children in Australia; however, an effective form of therapy has not yet been found. This occurs as the immune system of the allergic individual overreacts when in contact with egg allergens...
IJMS, Vol. 21, Pages 5011: Potential Hepatotoxins Found in Herbal Medicinal Products: A Systematic Review International Journal of Molecular Sciences doi: 10.3390/ijms21145011 Authors: Nguyen Van Quan Tran Dang Xuan Rolf Teschke The risk of liver injury associated with the use of herbal medicinal products (HMPs) is well known among physicians caring for patients under a HMP therapy, as documented in case reports or case series and evidenced by using the Roussel Uclaf Causality...
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JCDD, Vol. 7, Pages 25: Why Some Patients Undergoing Lipoprotein Apheresis Therapy Develop New Cardiovascular Events? Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7030025 Authors: Ulrich Julius Solveig Kuss Sergey Tselmin Ulrike Schatz Stefan R. Bornstein Lipoprotein apheresis (LA) is an effective tool to reduce cardiovascular events (CVEs) in high-risk patients with elevations of low density lipoprotein-cholesterol (LDL-C) and/or Lipoprotein(a) (Lp(a))....
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