Related Articles The relationship between neurosensory disturbance of the inferior alveolar nerve and the lingual split pattern after sagittal split osteotomy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 25;: Authors: Martinez-de la Cruz G, Yamauchi K, Saito S, Suzuki H, Yamaguchi Y, Kataoka Y, Nogami S, Takahashi T Abstract OBJECTIVE: The aim of this study was to evaluate the relationship between neurosensory disturbance (NSD)...
Thu Jul 16, 2020 15:27
Related Articles Oral cancer in Papua New Guinea: looking back and looking forward. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 20;: Authors: Kelwaip RA, Fose S, Siddiqui MS, Molumi CP, Apaio LM, Conway DI, Johnson NW, Thomas SJ, Lambert DW, Hunter KD Abstract Oral diseases, including cancers, affect 3.5 billion people globally and remain largely untreated in low- to middle-income countries because of lack of resources. In Papua...
Thu Jul 16, 2020 15:27
Related Articles Frequency of BRAF V600E mutation in a group of Thai patients with ameloblastomas. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 10;: Authors: Lapthanasupkul P, Laosuk T, Ruangvejvorachai P, Aittiwarapoj A, Kitkumthorn N Abstract OBJECTIVE: BRAF V600E mutation has recently been reported in a high proportion of ameloblastomas. This study was conducted to investigate the frequency of this mutation in ameloblastoma and...
Thu Jul 16, 2020 15:27
Related Articles Stenosis and stenosis-like lesions in the submandibular duct: detailed clinical and sialendoscopy-based analysis and proposal for a classification. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 05;: Authors: Koch M, Zenk J, Iro H Abstract OBJECTIVE: The aim of this study was to perform a detailed analysis of submandibular duct stenoses and propose a classification for them. STUDY DESIGN: This retrospective...
Thu Jul 16, 2020 15:27
Related Articles Bitewing radiography dosimetry of a stationary intraoral tomosynthesis imaging system. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 17;: Authors: Johnson KB, LaPrade JC, Platin E, Broome AM, Ludlow JB, Mol A Abstract OBJECTIVES: This study assessed effective doses (E) from conventional and stationary intraoral tomosynthesis (s-IOT) radiography for posterior bitewing (PBW) examinations and evaluated the effect of...
Thu Jul 16, 2020 15:27
Related Articles Tigecycline-Induced Severe Hypoglycemia in a Non-Diabetic Individual: A Case Report and Brief Review of Tigecycline-Induced Severe Hypoglycemia. Am J Case Rep. 2020 Jul 15;21:e924556 Authors: Ray A, Sharma S, Atal S, Sadasivam B, Jhaj R Abstract BACKGROUND Tigecycline is a broad-spectrum antibiotic belonging to the glycylcycline class. Hypoglycemia is a rare adverse effect associated with its use. We report a case of multiple...
Thu Jul 16, 2020 15:13
Related Articles Current Status of Neurosurgical and Neurointensive Care Units in Korea : A Brief Report on Nationwide Survey Results. J Korean Neurosurg Soc. 2020 Jul;63(4):519-531 Authors: Jo KW, Kim H, Yoo DS, Hyun DK, Cheong JH, Park HK, Park BJ, Cho BM, Kim YW, Kim TH, Han I, Lee SW, Kwon TH Abstract OBJECTIVE: The purpose of this study is identify the operation status of the neurosurgical care units (NCUs) in neurosurgical residency training...
Thu Jul 16, 2020 15:11
Related Articles Access to Operative Intervention Reduces Mortality in Adult Burn Patients in a Resource-Limited Setting in Sub-Saharan Africa. World J Surg. 2020 Jul 14;: Authors: Gallaher JR, Banda W, Robinson B, Purcell LN, Charles A Abstract INTRODUCTION: Early excision and grafting remains the standard of care after burn injury. However, in a resource-limited setting, operative capacity often limits patient access to surgical intervention....
Thu Jul 16, 2020 16:05
Related Articles Post traumatic vertebral arterio-venous fistula: a lifeline from tetraplegia? World Neurosurg. 2020 Jul 12;: Authors: Zanin L, Belotti F, Frigerio M, Mardighian D, Ferrara M, Panciani P, Fontanella MM Abstract BACKGROUND: Vertebral artery rupture is a rare condition that occurs about in 0,5% of cervical trauma. The management of our case was complicated by a spinal epidural hematoma (SEH) leading to worsening neurological deficits....
Thu Jul 16, 2020 14:27
Related Articles Preliminary Findings after Non-Surgical Management of Traumatic Cervical Spinal Cord Injury on a background of degenerative disc disease: Providing Optimum Patient Care While Saving Costs in a Nigerian Setting. World Neurosurg. 2020 Jul 12;: Authors: Adedigba JA, Oremakinde AA, Huang B, Maulucci CM, Malomo AO, Shokunbi TM, Adeolu AA Abstract PURPOSE: To assess the hypothesis that nonsurgical management is a viable treatment...
Thu Jul 16, 2020 14:27
Related Articles Primary intracranial mesenchymal tumor with EWSR1-CREM gene fusion: a case report and literature review. World Neurosurg. 2020 Jul 12;: Authors: Liu C, Liu Y, Zhao Y, Wei J, Ma Y, Liu Y, Huang J Abstract BACKGROUND: The prevalence of gene translocation in some mesenchymal tumors can be used as highly specific molecular diagnostic markers in clinic and pathology. EWSR1 is a partner gene in a large, diverse range of mesenchymal...
Thu Jul 16, 2020 14:27
Related Articles Two Cases of Large Filar Cyst Associated with Terminal Lipoma: Relationship with Retained Medullary Cord. World Neurosurg. 2020 Jul 12;: Authors: Mukae N, Morioka T, Suzuki SO, Murakami N, Shimogawa T, Kanata A, Tsukamoto H, Mizoguchi M Abstract BACKGROUND: Small, incidental filar cyst associated with terminal lipoma is thought to be caused by failure of secondary neurulation; however, the precise embryological background is...
Thu Jul 16, 2020 14:27
Related Articles Utilization of intracranial pressure monitoring in patients with severe traumatic brain injury. World Neurosurg. 2020 Jul 12;: Authors: Hoffman H, Bunch KM, Furst T, Chin LS Abstract OBJECTIVE: The Brain Trauma Foundation (BTF) recommends intracranial pressure (ICP) monitoring for all salvageable patients with an abnormal CT scan and a Glasgow Coma Scale less than 9. Studies have demonstrated that compliance with this is low....
Thu Jul 16, 2020 14:27
Related Articles Activation of the Nrf2 response by oleanolic acid oxime morpholide (3-hydroxyiminoolean-12-en-28-oic acid morpholide) is associated with its ability to induce apoptosis and inhibit proliferation in HepG2 hepatoma cells. Eur J Pharmacol. 2020 Jul 12;:173307 Authors: Narożna M, Krajka-Kuźniak V, Kleszcz R, Bednarczyk-Cwynar B, Szaefer H, Baer-Dubowska W Abstract Our previous study demonstrated that new oleanolic acid oxime...
Thu Jul 16, 2020 14:24
Related Articles The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation. Cell Rep. 2020 Jul 14;32(2):107901 Authors: Lockhead S, Moskaleva A, Kamenz J, Chen Y, Kang M, Reddy AR, Santos SDM, Ferrell JE Abstract Protein synthesis inhibitors (e.g., cycloheximide) block mitotic entry, suggesting that cell cycle progression requires protein synthesis until right before mitosis. However, cycloheximide is...
Thu Jul 16, 2020 14:24
Related Articles PTEN Inhibition Accelerates Corneal Endothelial Wound Healing through Increased Endothelial Cell Division and Migration. Invest Ophthalmol Vis Sci. 2020 Jul 01;61(8):19 Authors: Zhang W, Yu F, Yan C, Shao C, Gu P, Fu Y, Sun H, Fan X Abstract Purpose: To investigate the role of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) in the regulation of corneal endothelial cell (CECs) focusing on proliferation and...
Thu Jul 16, 2020 14:24
Related Articles Calponin 3 is associated with poor prognosis and regulates proliferation and metastasis in osteosarcoma. Aging (Albany NY). 2020 Jul 14;12: Authors: Dai F, Luo F, Zhou R, Zhou Q, Xu J, Zhang Z, Xiao J, Song L Abstract Osteosarcoma is a malignant, life-threatening tumor that affects children and adolescents. In this study, we identified high levels of calponin 3 (CNN3) protein in osteosarcoma tissues and cell lines. The...
Thu Jul 16, 2020 14:24
Related Articles Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†. Biol Reprod. 2020 Jun 12;: Authors: Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT Abstract WEE2 oocyte meiosis inhibiting kinase is a well-conserved oocyte specific kinase with a dual regulatory role during meiosis. Active WEE2 maintains immature, germinal vesicle stage...
Thu Jul 16, 2020 14:24
Related Articles Sauchinone: a prospective therapeutic agent-mediated EIF4EBP1 down-regulation suppresses proliferation, invasion and migration of lung adenocarcinoma cells. J Nat Med. 2020 Jul 15;: Authors: Li SQ, Feng J, Yang M, Ai XP, He M, Liu F Abstract Lung adenocarcinoma (LUAD) is the top prevalent histological kind of lung cancer worldwide. Recent evidences have demonstrated that Sauchinone plays an anticancer role in tumor cell...
Thu Jul 16, 2020 13:26
Related Articles CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPP. Mol Neurobiol. 2020 Jul 15;: Authors: Yang SH, Huang CY, Hsieh CY, Chuang JI Abstract Mild hypothermia has promising effects in the treatment of acute brain insults and also affects cell cycle progression. Mitochondrial dynamics, fusion and fission, are changed along with...
Thu Jul 16, 2020 13:26
Related Articles Synergistic anti-tumor activity of miriplatin and radiation through PUMA-mediated apoptosis in hepatocellular carcinoma. J Gastroenterol. 2020 Jul 14;: Authors: Tanaka H, Okamoto K, Sato Y, Tanaka T, Tomonari T, Nakamura F, Fujino Y, Mitsui Y, Miyamoto H, Muguruma N, Morita A, Ikushima H, Takayama T Abstract BACKGROUND: The prognosis for patients with unresectable advanced hepatocellular carcinoma (HCC) is poor. Miriplatin...
Thu Jul 16, 2020 13:26
Related Articles Biofilm-based fermentation: a novel immobilisation strategy for Saccharomyces cerevisiae cell cycle progression during ethanol production. Appl Microbiol Biotechnol. 2020 Jul 14;: Authors: Liang C, Ding S, Sun W, Liu L, Zhao W, Zhang D, Ying H, Liu D, Chen Y Abstract Biofilm-based fermentation, as a new immobilisation strategy, is beneficial for industrial fermentation due to its excellent environmental resistance, high...
Thu Jul 16, 2020 13:26
Related Articles E2F-dependent transcription determines replication capacity and S phase length. Nat Commun. 2020 Jul 14;11(1):3503 Authors: Pennycook BR, Vesela E, Peripolli S, Singh T, Barr AR, Bertoli C, de Bruin RAM Abstract DNA replication timing is tightly regulated during S-phase. S-phase length is determined by DNA synthesis rate, which depends on the number of active replication forks and their velocity. Here, we show that E2F-dependent...
Thu Jul 16, 2020 13:26
Related Articles HCN channel activity balances quiescence and proliferation in neural stem cells and is a selective target for neuroprotection during cancer treatment. Mol Cancer Res. 2020 Jul 14;: Authors: Johard HAD, Omelyanenko A, Fei G, Zilberter M, Dave Z, Abu-Youssef R, Schmidt L, Harisankar A, Vincent T, Walfridsson J, Nelander S, Harkany T, Blomgren K, Andäng M Abstract Children suffering from neurological cancers undergoing chemotherapy...
Thu Jul 16, 2020 13:26
Related Articles Synthesis and in vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4-Thiazolidinediones as Potential Anticancer Agents. Anticancer Agents Med Chem. 2020 Jul 14;: Authors: Yadav U, Vanjari Y, Laxmikeshav K, Tokala R, Niggula PK, Kumar M, Talla V, Kamal A, Shankaraiah N Abstract OBJECTIVE: To synthesize a series of phenanthrene-thiazolidinedione hybrids and explore their cytotoxic potential against human cancer cell...
Thu Jul 16, 2020 13:26
Related Articles Synergistic antitumor efficacy of hybrid micelles with mitochondrial targeting and stimuli-responsive drug release behavior. J Mater Chem B. 2019 03 07;7(9):1415-1426 Authors: Chen Z, Zhang Z, Chen M, Xie S, Wang T, Li X Abstract The term synergism means that the overall therapeutic benefits should be greater than the sum of the effects of individual agents and that the optimal therapeutic efficacy can be achieved at reduced...
Thu Jul 16, 2020 13:26
Related Articles YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity. Nat Commun. 2020 03 19;11(1):1472 Authors: Yuan Y, Park J, Feng A, Awasthi P, Wang Z, Chen Q, Iglesias-Bartolome R Abstract The Hippo TEAD-transcriptional regulators YAP1 and TAZ are central for cell renewal and cancer growth; however, the specific downstream gene networks involved in their activity...
Thu Jul 16, 2020 13:26
Related Articles Sequencing of a 'mouse azoospermia' gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest. Hum Reprod. 2019 06 04;34(6):978-988 Authors: Riera-Escamilla A, Enguita-Marruedo A, Moreno-Mendoza D, Chianese C, Sleddens-Linkels E, Contini E, Benelli M, Natali A, Colpi GM, Ruiz-Castañé E, Maggi M, Baarends WM, Krausz C Abstract STUDY QUESTION: What is the diagnostic...
Thu Jul 16, 2020 13:26
Related Articles MEG3 promotes liver cancer by activating PI3K/AKT pathway through regulating AP1G1. Eur Rev Med Pharmacol Sci. 2019 Feb;23(4):1459-1467 Authors: Sun Y, Cao FL, Qu LL, Wang ZM, Liu XY Abstract OBJECTIVE: This study aims to explore the biological function of maternally expressed gene 3 (MEG3) in liver cancer and the potential mechanism of phosphatidylinositide 3-kinases/protein kinase B (PI3K/AKT) pathway in regulating proliferation...
Thu Jul 16, 2020 13:26
Related Articles LncRNA 00152 promotes the development of hepatocellular carcinoma by activating JAK2/STAT3 pathway. Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1038-1046 Authors: Li SJ, Sui MH, Sun ZX, Zhang WW Abstract OBJECTIVE: The aim of this study was to explore the regulatory role of lncRNA 00152 and JAK2/STAT3 pathway in the pathogenesis of hepatocellular carcinoma (HCC), and to investigate the possible underlying mechanism. ...
Thu Jul 16, 2020 13:26
Related Articles Involvement of the Benzodiazepine Site in the Anticonvulsant Activity of Tapinanthus globiferus against Pentylenetetrazole-induced Seizures in Mice. Planta Med. 2020 Jul 15;: Authors: Elusiyan CA, Faria ALG, Mendes AEQ, Silva IO, Martins JLR, Rosa DA, Pedrino GR, Costa EA, Ibrahim MA, Zjawiony JK, Fajemiroye JO Abstract Tapinanthus globiferus is often referred to as an all-purpose herb for the treatment of stroke and epilepsy....
Thu Jul 16, 2020 14:38
Related Articles Mice Lacking Connective Tissue Growth Factor in the Forebrain Exhibit Delayed Seizure Response, Reduced C-Fos Expression and Different Microglial Phenotype Following Acute PTZ Injection. Int J Mol Sci. 2020 Jul 12;21(14): Authors: Siow PF, Tsao CY, Chang HC, Chen CY, Yu IS, Lee KY, Lee LJ Abstract Connective tissue growth factor (CTGF) plays important roles in the development and regeneration of the connective tissue, yet its...
Thu Jul 16, 2020 14:38
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