Publication date: Available online 16 July 2020Source: American Journal of OtolaryngologyAuthor(s): Ellen H. Ko-Keeney, Manick S. Saran, Kelly McLaughlin, Sidney Lipman
Thu Jul 16, 2020 19:09
Publication date: Available online 15 July 2020Source: American Journal of OtolaryngologyAuthor(s): Ishwarya S. Mamidi, Daniel A. Benito, Ryan Lee, Punam Thakkar, Joseph F. Goodman, Arjun S. Joshi
Thu Jul 16, 2020 19:09
Publication date: Available online 15 July 2020Source: American Journal of OtolaryngologyAuthor(s): Ashwin Ganti, Michael Eggerstedt, Kevin Grudzinski, Emily A. Ramirez, Deborah Vaughan, Peter C. Revenaugh, Kerstin Stenson, Samer Al-Khudari
Thu Jul 16, 2020 19:09
Publication date: Available online 15 July 2020Source: American Journal of OtolaryngologyAuthor(s): Daniel B. Hilton, Alexander L. Luryi, Dennis I. Bojrab, Seilesh C. Babu, Robert S. Hong, Dennis I. Bojrab, Olga J. Santiago Rivera, Christopher A. Schutt
Thu Jul 16, 2020 19:09
Publication date: Available online 15 July 2020Source: American Journal of OtolaryngologyAuthor(s): Michael Eggerstedt, Jessica Rhee, Matthew J. Urban, Angelica Mangahas, Ryan M. Smith, Peter C. Revenaugh
Thu Jul 16, 2020 19:09
Publication date: Available online 15 July 2020Source: Auris Nasus LarynxAuthor(s): Kayoko Mizuno, Yuji Kanazawa, Masato Takeuchi, Yo Kishimoto, Koji Kawakami, Koichi Omori
Thu Jul 16, 2020 15:44
Publication date: Available online 15 July 2020Source: Auris Nasus LarynxAuthor(s): Yue-Lin Hsieh, Xiaobing Xu, Ping Guo, Wuqing Wang
Thu Jul 16, 2020 15:44
Conditions: Oral Cancer; Induction Chemotherapy; Programmed Cell Death 1 Inhibitor; Inductive TherapyInterventions: Drug: Toripalimab; Drug: Paclitaxcel; Drug: Cisplatin; Procedure: Radical surgery; Radiation: Post-operative radiotherapy/chemoradiotherapySponsor: Shanghai Jiao Tong University School of MedicineNot yet recruiting
Thu Jul 16, 2020 19:00
Conditions: Solid Tumor, Adult; Squamous Cell Carcinoma of Head and Neck; Colorectal Adenocarcinoma; Metastatic Solid Tumor; Recurrent Solid Tumor; Head and Neck CancerInterventions: Drug: NT219; Drug: NT219 and ERBITUX® - Dose Escalation; Drug: NT219 and ERBITUX® - ExpansionSponsor: TyrNovo Ltd.Not yet recruiting
Thu Jul 16, 2020 19:00
Condition: Advanced Solid TumorInterventions: Drug: Donafenib; Drug: CS1001Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,LtdNot yet recruiting
Thu Jul 16, 2020 19:00
Abstract Background In this meta‐analysis, we compared the risk of obtaining nondiagnostic results and the diagnostic accuracy for detection of salivary gland malignancy between core needle biopsy (CNB) and fine‐needle aspiration (FNA). Methods All published English‐language studies comparing CNB and FNA diagnostic accuracy for salivary gland masses through December 2019 were searched. Pooled risk ratios (RRs) of nondiagnostic results, sensitivities, and specificities of CNB and FNA for...
Thu Jul 16, 2020 11:37
Related Articles In-office endoscopic nasal polypectomy: prospective analysis of patient tolerability and efficacy. Eur Arch Otorhinolaryngol. 2020 Jul 14;: Authors: Viera-Artiles J, Corriols-Noval P, López-Simón E, González-Aguado R, Lobo D, Megía R Abstract PURPOSE: In-office rhinologic procedures have become popularised in the last decade, especially in North America. Endoscopic nasal polypectomy under local anaesthesia offers instant relief...
Thu Jul 16, 2020 15:23
Related Articles The (head and neck) carcinologic handicap index: validation of a modular type questionnaire and its ability to prioritise patients' needs. Eur Arch Otorhinolaryngol. 2020 Jul 14;: Authors: Balaguer M, Champenois M, Farinas J, Pinquier J, Woisard V Abstract PURPOSE: To validate the upgraded version of the CHI with two new dimensions ("limitation of neck and/or shoulder movements", "changes in physical appearance"). To assess...
Thu Jul 16, 2020 15:23
Related Articles Causes of nutrition deficit during immediate postoperative period after free flap surgery for cancer of the head and neck. Eur Arch Otorhinolaryngol. 2020 Jul 14;: Authors: Nurkkala J, Lahtinen S, Kaakinen T, Vakkala M, Liisanantti J Abstract PURPOSE: The aim of the present of study was to examine nutrition deficit during the immediate postoperative in-hospital period following free flap surgery for cancer of the head and neck...
Thu Jul 16, 2020 15:23
Related Articles Use of IMAGE1 S technology for detection of cholesteatoma in endoscopic ear surgery: a retrospective case series on 45 patients. Eur Arch Otorhinolaryngol. 2020 Jul 14;: Authors: Lucidi D, Fernandez IJ, Martone A, Molinari G, Bonali M, Villari D, Alicandri-Ciufelli M, Presutti L Abstract PURPOSE: To evaluate the role of selected modalities of Storz Professional Image Enhancement System (IMAGE1 S) in differentiating cholesteatoma...
Thu Jul 16, 2020 15:23
Related Articles Comparison of middle ear function and hearing thresholds in children with adenoid hypertrophy after microdebrider and conventional adenoidectomy: a randomised controlled trial. Eur Arch Otorhinolaryngol. 2020 Jul 14;: Authors: Rajan N, Saxena SK, Parida PK, Alexander A, Ganesan S Abstract BACKGROUND: Microdebrider has superior efficacy in clearing the adenoids, compared to curettage. We compared the improvement in middle ear...
Thu Jul 16, 2020 15:23
This case series study describes a modified technique for pediatric microlaryngoscopy and bronchoscopy for use in the COVID-19 era.
Wed Jul 01, 2020 03:00
Mission Statement: JAMA Otolaryngology–Head & Neck Surgery provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinical, translational, and population health research from an array of disciplines. We place a high priority on strong study designs that accurately identify etiologies, evaluate diagnostic strategies,...
Wed Jul 01, 2020 03:00
This case series study seeks to identify and describe rhinologic procedures after facial transplants to assess the clinical and radiologic indications for intervention as well as the outcomes after intervention.
Wed Jul 01, 2020 03:00
This narrative review summarizes the evidence associated with screening for human papillomavirus–positive oropharyngeal cancer.
Wed Jul 01, 2020 03:00
In the Research Letter titled, “Negative-Pressure Aerosol Cover for COVID-19 Tracheostomy,” published online April 28, 2020, the funding source and role of the funder were omitted. The article has been corrected online.
Wed Jul 01, 2020 03:00
In this issue of JAMA Otolaryngology–Head & Neck Surgery, Zhao and colleagues report a meta-analysis on the association of preoperative patient-related factors with adult cochlear implant (CI) speech perception outcomes. Through pooled analysis, encompassing 13 articles and 1095 patients, the authors demonstrate statistically significant, yet modest at best, association between postoperative CI speech perception measures and commonly used variables: age of implantation (r = −0.31), duration of...
Wed Jul 01, 2020 03:00
This randomized clinical trial evaluates the effectiveness of adenotonsillectomy compared with watchful waiting in children aged 2 and 4 years who experience mild to moderate obstructive sleep apnea.
Wed Jul 01, 2020 03:00
This case-control study seeks to devise and evaluate a drape system to control the droplet spray during mastoidectomy.
Wed Jul 01, 2020 03:00
Obstructive sleep apnea (OSA) in children is characterized by snoring, disrupted sleep, and daytime sequelae such as hyperactivity and poor behavior. The severity of OSA in children is classified according to the apnea–hypopnea index (AHI) on full-night polysomnography (PSG). Children with an AHI score greater than 1 or 2 and less then 10 are considered to have mild to moderate OSA (nonsevere disease). Traditionally, adenotonsillectomy has been the primary treatment for pediatric OSA. However, over...
Wed Jul 01, 2020 03:00
A man in his 30s with a history of HIV and syphilis presented to the emergency department with dyspnea and stridor; examination findings revealed violaceous nodules and a subepithelial spindle cell lesion. What is your diagnosis?
Wed Jul 01, 2020 03:00
This essay reflects on being a resident at the time of coronavirus disease 2019 and advocates for a role for residents in the response to the pandemic.
Wed Jul 01, 2020 03:00
This meta-analysis of 13 studies comprising 1095 patients provides associations of patient-related factors with cochlear implant speech recognition outcomes.
Wed Jul 01, 2020 03:00
This cross-sectional study characterizes otolaryngologist participation and performance in the Merit-Based Incentive Payment System in 2017.
Wed Jul 01, 2020 03:00
A 44-year-old woman presents with an asymptomatic enlarging right parotid mass, with histologic findings compatible with salivary gland carcinoma and demonstrating microcystic and papillary architecture. What is your diagnosis?
Wed Jul 01, 2020 03:00
In Reply We thank Milkov and Pazardzhikliev for their report of a second case of permanent facial paralysis and hearing loss following aural irrigation. In the case we reported the ear discharge did not undergo testing with a microbiological culture, but the condition did respond to our prescribed antibiotic treatment of 250 mg of oral ciprofloxacin twice daily for 1 month. The patient was not known to have diabetes.
Wed Jul 01, 2020 03:00
This quality improvement study evaluates the use of a novel negative-pressure aerosol reduction cover for use during tracheostomy in a patient with confirmed or suspected COVID-19.
Wed Jul 01, 2020 03:00
This case report describes a woman in her 20s who presented with dyspnea during exercise and an inspiratory stridor when lying down, as well as dysphagia and a globus sensation for 2 months, and was subsequently diagnosed with primary intralymphatic histiocytosis.
Wed Jul 01, 2020 03:00
Beyond any doubt, it is clear that the worldwide coronavirus disease 2019 (COVID-19) pandemic has rattled the sphere of health care in an unprecedented manner. Physicians, other clinicians, and leaders of health care institutions have been thrust into previously unfathomable situations in which the urgent needs of patients are deferred, clinicians are at risk of acute disease and even death, and non–COVID-19–related clinical operations are reduced substantially. Still, amid the scrambling to adjust...
Wed Jul 01, 2020 03:00
To the Editor We read with great interest the article of Ahmed et al titled “Permanent Facial Paralysis and Hearing Loss After Aural Irrigation.” Their report illustrates very well how a simple aural irrigation can lead to serious consequences. We would like to discuss their case report and share a similar case from our own experience.
Wed Jul 01, 2020 03:00
This cohort study analyzes the association between postsurgical hyposmia and/or anosmia and a variety of patient, disease, and treatment factors among patients with primary sellar lesions.
Wed Jul 01, 2020 03:00
This qualitative study develops a comprehensive profile of items that describe how quality of life is associated with hearing loss and its treatments that can be used to generate hearing-related quality of life measures, including a novel utility measure.
Wed Jul 01, 2020 03:00
This case report describes a woman infected by SARS-CoV-2 who had sudden and complete loss of the olfactory function without nasal obstruction.
Wed Jul 01, 2020 03:00
This review evaluates the reporting and definition of minimal clinically important differences in randomized clinical trials.
Thu Jul 16, 2020 03:00
This cross-sectional study assesses the prevalence of specific ingredients in over-the-counter sinonasal products found in US pharmacies.
Thu Jul 16, 2020 03:00
To the Editor We read the recent articles by Eliezier et al in JAMA Otolaryngology–Head and Neck Surgery and Mao et al in JAMA Neurology, respectively, with great interest. Eliezier et al describe the important case of a woman in her 40s who presented with an olfactory loss secondary to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and Mao et al describe neurologic manifestations of hospitalized patients with SARS-Cov-2 infection in China. They found that around 5% had a...
Thu Jul 16, 2020 03:00
In Reply We read with great interest the recent letters by Lechner et al, Malnic and Glezer, and Kheok and Yang in JAMA Otolaryngology–Head and Neck Surgery regarding our recent study. There is now strong evidence that patients with proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection might develop loss of smell and taste, and in some cases this might constitute the main symptom.
Thu Jul 16, 2020 03:00
To the Editor There is increasing interest in the cause of anosmia in patients with coronavirus disease 2019 (COVID-19), and the article written by Dr Eliezer et al, presents an interesting finding of a patient with bilateral obstruction of the olfactory clefts. This is different from another report of a COVID-19 patient with isolated anosmia whose magnetic resonance imaging results showed normal olfactory bulb and no corresponding inflammation in the olfactory clefts or paranasal sinuses.
Thu Jul 16, 2020 03:00
This case report describes a woman in her 30s who presented with sinonasal metastasis secondary to radioiodine-refractory vesicular thyroid carcinoma.
Thu Jul 16, 2020 03:00
This Viewpoint highlights some techniques to overcome barriers to care that people with hearing loss encounter during the COVID-19 pandemic.
Thu Jul 16, 2020 03:00
To the Editor Eliezer and colleagues reported a case where the main symptom expressed by the patient infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the sudden and complete loss of the olfactory function without nasal obstruction. Computed tomographic and magnetic resonance imaging of the nasal cavity showed bilateral inflammatory obstruction of the patient’s olfactory clefts. We recognize that this approach should reveal important aspects about the possible association...
Thu Jul 16, 2020 03:00
Thyroid, Ahead of Print.
Tue Jul 14, 2020 10:00
Thyroid, Ahead of Print.
Tue Jul 14, 2020 10:00
A tracheostomy performed on patients infected with SARS CoV-2 is one of the procedures with the highest risks of aerosolization. Safety recommendations for carrying out this procedure are not suitable for implementation in every hospital. Despite the use of Personal Protection Equipment (PPE), the suit leaves the submental area unprotected, and even the face mask may not provide a full seal. The use of additional biosafety isolation equipment increases safety, thus preventing exposure to infecting...
Wed Jul 15, 2020 03:00
Controlled substance agreements between providers and patients represent important strategies for setting expectations for chronic opioid therapy. These agreements generally summarize best opioid prescription practices and destigmatize practice policies such as regular toxicology screenings. These controlled substance agreements also set expectations for discontinuation of therapy if appropriate.
Thu Jul 16, 2020 03:00
Pain is epidemic in patients with head and neck cancer. Providers involved in the care of patients with head and neck cancer should be able to describe the common pain syndromes experienced by these patients, identify patients at risk of pain, and provide multimodal treatment of chronic pain. Treatment of chronic pain encompasses analgesic medications; adjuvant pharmacotherapy, including antidepressants and anticonvulsants; interventional techniques; as well as integrative medicine.
Thu Jul 16, 2020 03:00
In the last 30 years, pain control in the United States has undergone several evolutions impacting the care of surgical patients. More recently, safe pain control has been a subject of quality improvement efforts by otolaryngologists focusing on minimizing opioid consumption. This article discusses the rising overprescription of opioids, influenced by legislation and governmental agencies, and the steps taken to correct and reform policies to decrease the amount of opioids prescribed. Lastly, specific...
Thu Jul 16, 2020 03:00
Abstract The parotid gland is the largest salivary gland in the body. Pleomorphic adenomas (PA) are most common benign tumors of parotid gland. If left untreated, they can gradually attain the size which can weigh several kilograms. This paper highlights a case series of 15 cases diagnosed as giant pleomorphic adenoma arising in the parotid gland along with their management. A hospital based, observational study of 15 patients of PA of the parotid gland, > 10 cm in its widest...
Thu Jul 16, 2020 03:00
Abstract The aim of this study was to evaluate sphenoid sinus pneumatisation and its anatomical relation with adjacent neurovascular structures in Indian population. We performed a retrospective cross-sectional study, in which the pattern of sphenoid sinus pneumatization was studied on high-resolution computed tomography scans (n = 400), and association of the optic nerve, vidian canal and foramen rotundum along with related morphometric measurements were studied. Out of 400 CT...
Thu Jul 16, 2020 03:00
Abstract This study was done to measure the outcomes of hearing aid (HA) and cochlear implantation (CI) in case of congenital non syndromic severe to profound sensorineural hearing loss (SNHL) by using aided audiometry (AA), categories of auditory perception (CAP) score and speech intelligibility rating (SIR) scale. The objectives were to find out the effective management options available for bilateral severe to profound SNHL, to study the impact of age of CI on language development...
Thu Jul 16, 2020 03:00
Objective: Menière's disease (MD) is characterized by episodes of vertigo, tinnitus, and sensorineural hearing loss. In the setting of bilateral deafness due to MD alone or contralateral pathology, cochlear implantation (CI) improves hearing. Active MD is characterized by fluctuating auditory symptoms and vertigo; whereas remittance of vertiginous symptoms and severe, permanent sensorineural hearing loss characterizes the inactive disease state. This study evaluates outcomes for MD patients...
Tue Jul 14, 2020 03:00
Objective: To evaluate a possible correlation between impedance values and speech perception after cochlear implantation. Study Design: Retrospective chart review. Setting: Tertiary referral center. Patients and Intervention: All patients implanted with a MedEl Flex28 device in our department with complete audiometric data (Freiburger monosyllabic testing at 65 dB, Hochmaier–Schulz–Moser testing in quiet and in 10 dB noise) and impedance measurements at the 1-year...
Tue Jul 14, 2020 03:00
Abstract Objective (1) To investigate whether office laryngoscopy is an aerosol‐generating procedure with an optical particle sizer (OPS) during clinical simulation on healthy volunteers, and (2) To critically discuss methods for assessment of aerosolizing potentials in invasive interventions. Study Design Prospective quantification of aerosol and droplet generation during clinical simulation of rigid and flexible laryngoscopy. Methods Two healthy volunteers were recruited to undergo...
Thu Jul 16, 2020 10:26
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