Condition: Squamous Cell Carcinoma of Head and NeckInterventions: Drug: Pembrolizumab; Drug: Carboplatin; Drug: PaclitaxelSponsor: Merck Sharp & Dohme Corp.Not yet recruiting
Conditions: Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Head and Neck Carcinoma of Unknown Primary; Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Interventions: Other: Medical Chart Review;...
Condition: Xerostomia Following RadiotherapyIntervention: Biological: Autologous bone-marrow derived, interferon gamma stimulated mesenchymal stromal cellsSponsor: University of Wisconsin, MadisonNot yet recruiting
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Bialveolar protrusion is one of the most common chief complaints from the Asian orthodontic patients. Typical orthodontic treatment includes extraction of the bimaxillary premolars and en mass retraction of an...
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Abstract Background The aim of this study is to estimate the incidence, mortality, and disability‐adjusted life years (DALYs) of nasopharyngeal carcinoma from 1990 to 2017. Methods We collected detailed information on nasopharyngeal carcinoma from 1990 to 2017 based on data from Global Burden of Disease (GBD) study 2017. The global incidence, mortality, and DALYs attributable to nasopharyngeal carcinoma was reported, as well as the age‐standardized rates (ASRs). Results The ASR of...
Abstract Background Identification of risk factors for perioperative complications helps in the prognostication. We wanted to determine whether Physiological and Operative Severity Score for the enumeration of mortality and morbidity (POSSUM) and Portsmouth‐POSSUM (P‐POSSUM) can be used in patients undergoing head and neck oncosurgery. Methods We conducted a retrospective analysis of 1265 patients after they had major head and neck oncosurgeries. Demographic, surgical and outcome data was...
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Abstract Here, we describe the surgical technique for implanting a new, active, transcutaneous bone conduction hearing aid. The implant technology is based on a system that has been in use reliably since 2012. The geometry of the new implant has been adapted based on experience with previously introduced implants. The surgery was feasible, standardized, and safe. Due to the optimized geometric design that improved the bone fit, it is not necessary to use specialized, detailed preoperative...
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Related Articles Greater palatine artery pedicled flap for nasal septal perforation repair: radiological study and case series. Eur Arch Otorhinolaryngol. 2020 Jul 24;: Authors: Santamaría-Gadea A, Vaca M, de Los Santos G, Alobid I, Mariño-Sánchez F Abstract PURPOSE: The greater palatine artery (GPA) is one of the main vessels supplying the nasal septum. We recently described a novel technique to reconstruct a nasal septal perforation (NSP)...
Tue Jul 28, 2020 16:10
Related Articles Assessment of Stroop Color Word Interference Test-TBAG form performance in subjects with tinnitus. Eur Arch Otorhinolaryngol. 2020 Jul 24;: Authors: Gonendik ZA, Mujdeci B, Karakurt SE, Dere HH Abstract PURPOSE: To evaluate ordinary behavioral pattern suppression performance of individuals with tinnitus under disruptive effect using Stroop Color Word Interference Test-TBAG Form (SCWT), and to determine the impact of acoustic...
Tue Jul 28, 2020 16:10
Related Articles Endoscopic transtympanic myringoplasty should be cautious for repairing large perforation. Eur Arch Otorhinolaryngol. 2020 Jul 24;: Authors: Lou Z PMID: 32710179 [PubMed - as supplied by publisher]
Tue Jul 28, 2020 16:10
Related Articles Sinus and anterior skull base surgery during the COVID-19 pandemic: systematic review, synthesis and YO-IFOS position. Eur Arch Otorhinolaryngol. 2020 Jul 24;: Authors: Radulesco T, Lechien JR, Sowerby LJ, Saussez S, Chiesa-Estomba C, Sargi Z, Lavigne P, Calvo-Henriquez C, Lim CM, Tangjaturonrasme N, Vatanasapt P, Puya DM, Fakhry N, Ayad T, Michel J Abstract PURPOSE: The COVID-19 pandemic has caused significant confusion about...
Tue Jul 28, 2020 16:10
Related Articles Postoperative management of antithrombotic medication in microvascular head and neck reconstruction: a comparative analysis of unfractionated and low-molecular-weight heparin. Eur Arch Otorhinolaryngol. 2020 Jul 24;: Authors: Sievert M, Goncalves M, Tamse R, Mueller SK, Koch M, Gostian AO, Iro H, Scherl C Abstract PURPOSE: Free flap reconstruction is a valuable technique to preserve function in oncological head and neck surgery....
Tue Jul 28, 2020 16:10
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Thyroid, Ahead of Print.
Thyroid, Ahead of Print.
Thyroid, Ahead of Print.
Thyroid, Ahead of Print.
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Publication date: Available online 27 July 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): S. Belleudy, M. Kérimian, P. Legrenzi, A. Alharbi, L. de Gabory
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Abstract BackgroundPerivascular epithelioid cell tumors (PEComas) represent a rare group of mesenchymal tumors with an unpredictable outcome. They are usually observed in middle‐aged women whilst they are very rare in children, with limited cases described. Due to the rare anatomical location in kidneys a correct diagnosis and treatment is really challenging.MethodsWe observed and treated a case of kidney's PEComa in a 14‐year‐old boy.ResultsAn individualized approach based on anatomical (3D CT‐reconstructions)...
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Objectives Laryngoscopes and subglottiscopes of multiple shapes and lengths are used in airway surgery to maintain an open airway; protect the trachea; and provide a place to mount the light, evacuator, and ventilation needle. Despite differences in scopes and ventilation needle mounting positions, the same jet pressures are typically used. We hypothesized that different scopes and scope configurations would affect distal airway pressure magnitude and homogeneity. Study Design A laboratory...
Objectives Nonautologous graft materials may solve several dilemmas in tympanoplasty by obviating the need for graft harvest, facilitating consistent wound healing, and permitting graft placement in the clinical setting. Prior studies of nonautologous grafts in humans have shown variable outcomes. In this systematic review, we aim to 1) summarize clinical outcomes and 2) discuss limitations in the literature regarding nonautologous grafts for tympanoplasty in humans. Methods A literature review...
Objectives Prader‐Willi syndrome (PWS) increases the risk of obstructive sleep apnea (OSA) due to obesity, hypotonia, and abnormal ventilatory responses. We evaluated post‐adenotonsillectomy complications, polysomnography changes, and quality of life in children with OSA and PWS. Study Design Systematic review and meta‐analysis. Methods We conducted a systematic review and meta‐analysis by searching PubMed, Embase, Cochrane, Web of Science, and Scopus. Two researchers independently reviewed...
ABSTRACT Objective(s) The overall aim of this study was to evaluate personal protective equipment (PPE) that may facilitate the safe recommencement of cochlear implantation in the COVID‐19 era with the broader goal of minimising the period of auditory deprivation in prelingually deaf children and reducing the risk of cochlear ossification in individuals following meningitis. Methods Using a preclinical model, an objective assessment of drill induced droplet spread was undertaken during...
Objectives/Hypothesis To review the management of failed free tissue transfers among four large institutions over a 13‐year period to provide data and analysis for a logical, algorithmic, experience‐based approach to the management of failed free flaps. Study Design Retrospective case series. Methods A multi‐institutional retrospective chart review of free tissue transfers to the head and neck region between 2006 and 2019 was performed. Patients with a failed free flap during their hospitalization...
Optimum naso‐oropharyngeal swab procedure for COVID‐19: step by step preparation and technical hints
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Background: PTEN hamartoma tumor syndrome (PHTS) represents a group of syndromes caused by a mutation in the PTEN gene. Children with a germline PTEN mutation have an increased risk of developing differentiated thyroid carcinoma (DTC). Several guidelines have focused on thyroid surveillance in these children, but studies substantiating these recommendations are lacking. Objective: The present study intends to provide the available evidence for a thyroid carcinoma surveillance program in children...
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