Publication date: Available online 28 July 2020Source: Behavioural Brain ResearchAuthor(s): Lorrane Kelle da Silva Moreira, Adriane Ferreira de Brito, Crisciele Fontana, Flávio Souza de Carvalho, Germán Sanz, Boniek Gontijo Vaz, Luciano Morais Lião, Fábio Fagundes da Rocha, Hugo Verli, Ricardo Menegatti, Elson Alves Costa
Tue Jul 28, 2020 14:53
Publication date: Available online 27 July 2020Source: CortexAuthor(s): Dock Duncan, Jan Theeuwes
Tue Jul 28, 2020 14:37
Summary Background Bruxism is a repetitive jaw‐muscle activity characterized by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. It can occur during sleep, indicated as sleep bruxism, or during wakefulness, indicated as awake bruxism. Exogenous risk indicators of sleep bruxism and/or awake bruxism are, among others, medications and addictive substances, whereas also several medications seem to have the potential to attenuate sleep bruxism and/or awake bruxism....
Mon Jul 27, 2020 18:34
Related Articles Conventionally fractionated large volume head and neck re-irradiation using multileaf collimator-based robotic technique: A feasibility study. Clin Transl Radiat Oncol. 2020 Sep;24:102-110 Authors: Bahig H, Wang C, Ping Ng S, Phan J Abstract Purpose: To report on the feasibility and performance of conventionally fractionated multileaf collimator (MLC)-based robotic stereotactic body re-irradiation of the head and neck region...
Tue Jul 28, 2020 13:48
Related Articles The Use of Balloon Eustachian Tuboplasty in Patients with Eustachian Tube Dysfunction: A Retrospective Pilot Usage Experience. Indian J Otolaryngol Head Neck Surg. 2020 Sep;72(3):392-394 Authors: Ramakrishnan N, Kadambi P Abstract Chronic eustachian tube dysfunction is a condition that affects a large number of adults every year. While many cases can be managed pharmacologically, there is a significant portion that does not...
Tue Jul 28, 2020 13:48
Related Articles Use of Solid Lipid Nanoparticles for the Treatment of Acute Acoustic Stress-Induced Cochlea Damage. J Nanosci Nanotechnol. 2020 Dec 01;20(12):7412-7418 Authors: Wang N, Gao X, Li M, Li Y, Sun M Abstract To study the effects of drug delivery using solid lipid nanoparticles in the treatment of acute noise exposure-induced cochlea damage. The solid lipid nanoparticles (SLNs) were used as carriers to effectively encapsulate the...
Tue Jul 28, 2020 13:48
Clinical Value of Fused PET/MRI for Surgical Planning in Patients With Oral/Oropharyngeal Carcinoma.
Related Articles Clinical Value of Fused PET/MRI for Surgical Planning in Patients With Oral/Oropharyngeal Carcinoma. Laryngoscope. 2020 02;130(2):367-374 Authors: Hayashi K, Kikuchi M, Imai Y, Yamashita D, Hino M, Ito K, Shimizu K, Harada H, Shinohara S Abstract OBJECTIVES/HYPOTHESIS: To evaluate the usefulness of fused positron emission tomography (PET)/magnetic resonance (MR) images for surgical planning in patients with oral/oropharyngeal...
Tue Jul 28, 2020 13:48
Related Articles A 3D-printed polycaprolactone/β-tricalcium phosphate mandibular prosthesis: A pilot animal study. Laryngoscope. 2020 02;130(2):358-366 Authors: Park JH, Jung SY, Lee CK, Ban MJ, Lee SJ, Kim HY, Oh HJ, Kim BK, Park HS, Jang SH, Kim HS Abstract OBJECTIVE: In this study, we assessed the effectiveness of a tonsil-derived mesenchymal stem cell (TMSC)-transplanted polycaprolactone/beta-tricalcium phosphate prosthesis (specifically...
Tue Jul 28, 2020 13:48
Related Articles Multidisciplinary care for people with Parkinson's disease: the new kids on the block! Expert Rev Neurother. 2019 02;19(2):145-157 Authors: Radder DLM, de Vries NM, Riksen NP, Diamond SJ, Gross D, Gold DR, Heesakkers J, Henderson E, Hommel ALAJ, Lennaerts HH, Busch J, Dorsey RE, Andrejack J, Bloem BR Abstract INTRODUCTION: Parkinson's disease (PD) is a chronic multisystem disorder that causes a wide variety of motor and non-motor...
Tue Jul 28, 2020 13:48
The aim of the present study was to compare the accuracy of the actual space obtained through interproximal enamel reduction (IPR) compared to the amount of IPR planned through the digital setup during clear a...
Tue Jul 28, 2020 03:00
Publication date: Available online 28 July 2020Source: Magnetic Resonance ImagingAuthor(s): Zhilun Wang, Haitao Jiang, Hongwei Du, Jinzhang Xu, Bensheng Qiu
Tue Jul 28, 2020 13:48
Siblings with hereditary spastic paraplegia and corpus callosum thinning associated with a novel TUBβ4A mutation.
Tue Jul 28, 2020 13:39
Abstract De novo pathogenic variants in CNOT3 have recently been reported in a developmental delay disorder (Intellectual Developmental Disorder with Speech Delay, Autism, and Dysmorphic Facies (IDDSADF, OMIM: # 618672)). The patients present with a variable degree of developmental delay and behavioral problems. To date, all reported disease causing variants occurred de novo and no parent‐child transmission was observed. We report for the first time autosomal dominant transmissions...
Mon Jul 27, 2020 19:33
Volume 52, Issue 1, May 2020, Page 45-80.
Tue Jul 28, 2020 12:50
Abstract In accordance with Article 6 of Regulation (EC ) No 396/2005, the applicant BASF Agro BV Arnhem submitted a request to the competent national authority in Austria to set and modify the maximum residue levels (MRL s) for the active substance mefentrifluconazole in various products of plant and animal origin. The data submitted in support of the request were found to be sufficient to derive MRL proposals for pome fruits, apricots, cherries, peaches, plums, grapes, potatoes, sweet corns,...
Mon Jul 27, 2020 13:40
Abstract Purpose To: (1) Evaluate intrauterine MRI (iuMRI) findings in fetuses with suspected cCMV and correlate these with final diagnosis(es). (2) Correlate iuMRI in cases of confirmed cCMV with clinical outcomes. Methods Retrospective cohort of iuMRI referrals for suspected cCMV between 2010 and 2018. Confirmed cCMV defined as positive amniotic fluid or postnatal CMV polymerase chain reaction (PCR) test and excluded cCMV defined by negative postnatal PCR. Results Twenty‐nine singleton...
Mon Jul 27, 2020 22:59
Abstract Introduction Nerve‐sparing prostatectomy is recommended in cases of organ‐confined prostate cancer but is generally contraindicated in patients with suspected extra‐prostatic extension (EPE). PSMA ligand imaging has been shown to be valuable in predicting EPE when performed on a hybrid PET/MRI scanner; however, the majority of PSMA PET imaging is performed using PET/CT. To our knowledge, there are no established PET/CT criteria for assessing EPE. In this study, we aim to provide a reproducible...
Mon Jul 27, 2020 22:41
Abstract Introduction Around 300 children in Australia and New Zealand (ANZ) undergo a course of radiation treatment (RT) each year. A fortnightly videoconference for radiation oncologists managing children started in 2013. We conducted an audit of the videoconference to assess its influence on the care of children who receive RT in ANZ. Methods De‐identified data from minutes (August 2013–December 2019) were analysed retrospectively using three categories: meeting participation, case presentations...
Mon Jul 27, 2020 22:40
Summary CT imaging for lung cancer screening requires low dose technique. Low dose CT chest imaging is associated with an increased risk of artefacts, such as increased noise. We present a case where an artefact from the low dose technique lead to a lung cancer being erroneously reported as a benign hamartoma.
Mon Jul 27, 2020 14:59
A 34‐year‐old Chinese woman found a lump in her left leg for more than 3 weeks without any discomfort. Grossly, the tumor was relatively well delineated with focal infiltration. Histopathologic evaluation showed a compact fascicular spindle cell proliferation with variable myxoid and collagenous stroma and scattered inflammatory infiltrate. Immunohistochemically, the tumor cells showed positive expression of ALKD5F3 and SMA and negative expression of CD34, desmin, and cytokeretin. Fluorescence in...
Mon Jul 27, 2020 12:19
Chronic myocarditis is sometimes difficult to diagnose using several clinical diagnostic modalities. A 43‐year‐old Japanese man was admitted to our hospital with heart failure due to a diffusely hypokinetic left ventricle. No abnormal accumulation was seen on 18F‐fluorodeoxyglucose positron emission tomography/computed tomography. Coronary angiography showed no abnormalities. Endomyocardial biopsy was performed on suspicion of dilated cardiomyopathy, revealing diffuse cell infiltration (more T lymphocytes...
Mon Jul 27, 2020 12:18
Publication date: Available online 28 July 2020Source: Gait & PostureAuthor(s): Rosangela Alice Batistela, Alison Oates, Andréia Abud da Silva Costa, Luciana Oliveira dos Santos, Renato Moraes
Tue Jul 28, 2020 13:01
OBJECTIVE: This review aimed at examining efficacy of interventional radiotherapy (brachytherapy-IRT) alone or combined with external beam radiotherapy (EBRT) in stage I esophageal cancer as exclusive treatment. MATERIALS AND METHODS: A systematic research using PubMed, Scopus, and Cochrane library was performed. ClinicalTrials.gov was searched for ongoing or recently completed trials, and PROSPERO was searched for ongoing or recently completed systematic reviews. We analyzed only clinical study...
Tue Jul 28, 2020 11:55
Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, “MiR-20a regulates fibroblast-like synoviocyte proliferation and apoptosis in rheumatoid arthritis, by X.-J. Wei, X.-W. Li, J.-L. Lu, Z.-X. Long, J.-Q. Liang, S.-B. Wei, C.-X. Lu, W.-Z. Lu, published in Eur Rev Med Pharmacol Sci 2017; 21 (17): 3886-3893–PMID: 28975975” has been withdrawn. The Publisher apologizes for any inconvenience...
Tue Jul 28, 2020 11:55
Female saki (Pithecia pithecia ) feeding on Inga pods (Photo by M. Norconk). Abstract The modern pitheciids (titis, sakis, and uakaris) of northern South America represent one of the earliest radiations of platyrrhines and demonstrate morphological adaptations and ecological strategies for seed eating. While seeds can provide reliable resources for relatively long periods of time, they are often well protected by thick husks and hard seed coverings. Seeds also tend to be rich in lipids,...
Mon Jul 27, 2020 21:47
The newly described Jonah's mouse lemur (Microcebus jonahi ) is distributed in northeastern Madagascar with an estimated Extent of Occurrence of about 1,500 km2. This species has a mean head‐body length of 13.0 cm, a mean tail length of 13.3 cm and weighs on average 57.4 g. Abstract Delimitation of cryptic species is increasingly based on genetic analyses but the integration of distributional, morphological, behavioral, and ecological data offers unique complementary insights into species...
Mon Jul 27, 2020 13:06
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Spontaneous tumor lysis syndrome (SPTLS) is a rare phenomenon that can manifest in rapidly proliferating hematological malignancies and solid tumors prior to initiating cytotoxic therapy. We encountered a patient who originally presented with diffuse lymphadenopathy, abdominal distention, and dyspnea, who had laboratory abnormalities suggestive of SPTLS. His peripheral flow cytometry and lymph node...
Tue Jul 28, 2020 11:55
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. We report the case of a 42-year-old woman who was diagnosed with breast cancer that recurred 3 years later, with supraclavicular lymphadenopathy and dermal involvement. The main drug used in the therapy was trastuzumab; however, the association of this drug with docetaxel was not able to decrease or cease the effect of the inflammatory BCA component with erythema and thickening of the skin as well...
Tue Jul 28, 2020 11:55
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Collagenous gastritis is a rare histopathologic entity that causes marked subepithelial collagen deposition in the gastric mucosa. Clinical presentation is diverse, considering only less than 100 cases have been reported. However, we report a unique case of isolated collagenous gastritis in a 71-year-old female who presented with a 6-month history of dyspepsia and 27 kg weight loss. Her endoscopic...
Tue Jul 28, 2020 11:55
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. COVID-19 (coronavirus disease-2019) infection is a highly prothrombotic state, resulting from a dysregulation of the coagulation cascade. Therefore, thromboprophylaxis is strongly recommended in these patients, with some experts even advocating for therapeutic dosing to prevent thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a well-known complication of heparin therapy. In this article,...
Tue Jul 28, 2020 11:55
Abstract Clonal haematopoiesis results from acquired mutations in haematopoietic stem and progenitor cells (HSPCs). These mutations can confer the HSPC with a competitive advantage, leading to their clonal expansion within the limiting bone marrow niche. This process is often insufficient to produce a haematologic malignancy; however, the expanding HSPC clones increasingly give rise to progeny leucocytes whose phenotypes can be altered by the somatic mutations that they harbour. Key...
Mon Jul 27, 2020 22:09
Abstract Several reports describe an higher risk for viral infections in patients with asthma.1,2 Novel coronavirus disease (COVID‐19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), that shows a predilection to infect the lower and upper airway tract, thus creating an higher clinical issue in asthmatic patients.3
Mon Jul 27, 2020 17:35
Abstract Background The impacts of chronic airway diseases on coronavirus disease 2019 (COVID‐19) are far from understood. Objective To explore the influence of asthma and chronic obstructive pulmonary disease (COPD) comorbidity on disease expression and outcomes, and the potential underlying mechanisms in COVID‐19 patients. Methods A total of 961 hospitalized COVID‐19 patients with a definite clinical outcome (death or discharge) were retrospectively enrolled. Demographic and clinical...
Mon Jul 27, 2020 17:33
Abstract When does a child become an adult? Transition does not happen at a particular instance, yet many health systems are poorly designed to acknowledge that transition from childhood to adult is a process which occurs over many years, as highlighted in this issue by a new Guideline from the EAACI Task Force on Adolescents and Young Adults.2 In many clinics in Europe, “paediatrics” stops at age 16 – at the very time when young people are undergoing the greatest changes in their lives. It is therefore...
Mon Jul 27, 2020 17:31
Mon Jul 27, 2020 14:56
Abstract Objectives Because trabecular bone volume fraction (BV/TV) is influenced by variations in physical activity recent declines in BV/TV in humans are often attributed to modern sedentary lifestyles. This study tests the hypothesis that presumed variations in mechanical loading between groups can predict the observed BV/TV patterns in humans, chimpanzees and gorillas in two bones: the calcaneus which experiences high and well characterized impact forces, and the C2 vertebrae which experiences...
Mon Jul 27, 2020 20:46
Abstract Development of the mammalian kidney is orchestrated by reciprocal interactions of stromal and nephrogenic mesenchymal cells with the ureteric bud epithelium. Previous work showed that the transcription factor WT1 acts in the nephrogenic lineage to maintain precursor cells, to drive the epithelial transition of aggregating precursors into a renal vesicle and to specify and maintain the podocyte fate. However, WT1 is not only expressed in the nephrogenic lineage but also transiently in stromal...
Mon Jul 27, 2020 22:38
Abstract Disturbed intrauterine development increases the risk of renal disease. Various studies have reported that the Notch signalling plays a significant role in kidney development and kidney diseases. A disintegrin and metalloproteinase domain 10 (ADAM10), an upstream protease of Notch pathway, is also reportedly involved in renal fibrosis. However, how ADAM10 interacts with Notch pathway and causes renal fibrosis is not fully understood. In this study, using a prenatal chlorpyrifos (CPF) exposure...
Mon Jul 27, 2020 22:38
Abstract Rates of gastroesophageal junction adenocarcinomas (GEJA) have shown an alarming increase, however, the genetic background of GEJA and its Siewert classification have yet to be uncovered. Here, 60 paired tumor and normal DNA from GEJA patients were analyzed by whole‐exome sequencing. Among them, 13 were Siewert type I, 14 were type II and 33 were type III. A predominance of C/G > T/A substitutions was discovered in GEJA, followed by C/G > A/T substitutions. Notably, Siewert type I...
Mon Jul 27, 2020 22:36
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