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Πέμπτη 16 Ιουλίου 2020


A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects
Publication date: October 2020Source: Biomedicine & Pharmacotherapy, Volume 130Author(s): Yan-Xi Zhou, Xiao-Hong Gong, Hong Zhang, Cheng Peng
Biomedicine & Pharmacotherapy
Thu Jul 16, 2020 20:12
Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/β-catenin pathway
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Min Zhao, Wei Ma, Chaonan Ma
Biomedicine & Pharmacotherapy
Thu Jul 16, 2020 20:12
The role of a knowledge based dose–volume histogram predictive model in the optimisation of intensity-modulated proton plans for hepatocellular carcinoma patients
Abstract Purpose To investigate the performance of a knowledge-based RapidPlan, for optimisation of intensity-modulated proton therapy (IMPT) plans applied to hepatocellular cancer (HCC) patients. Methods A cohort of 65 patients was retrospectively selected: 50 were used to “train” the model, while the remaining 15 provided independent validation....
Strahlentherapie und Onkologie
Thu Jul 16, 2020 03:00
Learning from a global pandemic
Taking on the job of Editor in Chief of Occupational and Environmental Medicine is a challenge, especially during a pandemic with enormous societal as well as environmental and occupational consequences. While we cannot fully anticipate the extent of these consequences, some lessons relevant for our research field and Occupational and Environmental Medicine are emerging.Rapidly executed research on the effects of the pandemic has already shed light on the occurrence of occupational and environmental...
OEM Online First
Thu Jul 16, 2020 19:00
Comprehensive Literature Review of Radiation Levels During Endovascular Aortic Repair in Cathlabs and Operating Theatres
Publication date: Available online 15 July 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Adrien Hertault, Aurélia Bianchini, Sébastien Amiot, Hovan Chenorhokian, Francine Laurent-Daniel, Nabil Chakfé, Anne Lejay
ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery
Thu Jul 16, 2020 19:45
Two-week rule: suspected head and neck cancer referrals from a general medical practice perspective
Publication date: Available online 15 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): C. Talwar, A. McClune, D. Kelly, D. Lowe, S.N. Rogers
British Journal of Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:39
Best practice in reducing the suicide risk in head and neck cancer patients: a structured review
Publication date: Available online 15 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): J.A. Twigg, J.M. Anderson, G. Humphris, I. Nixon, S.N. Rogers, A. Kanatas
British Journal of Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:39
Postoperative pulmonary complications following major head and neck cancer surgery
Publication date: Available online 15 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): L.M. Shaw, T.A. Iseli, D. Wiesenfeld, A. Ramakrishnan, C.L. Granger
Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:34
Preliminary experience with promethazine hydrochloride injection in the sclerotherapy of oral mucocele
Publication date: Available online 15 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): Y. Huang, C. Yang, T. Wang, S. Liu, A. Chen
Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:34
Comparison of cost-effectiveness and benefits of surgery-first versus orthodontics-first orthognathic correction of skeletal class III malocclusion
Publication date: Available online 15 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): J. Hu, Y. Jiang, D. Wang, S. Guo, S. Li, H. Jiang, J. Cheng
Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:34
Evaluating the accuracy of resection planes in mandibular surgery using a preoperative, intraoperative, and postoperative approach
Publication date: Available online 15 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): S.G. Brouwer de Koning, T.P. ter Braak, F. Geldof, R.L.P. van Veen, M.J.A. van Alphen, L.H.E. Karssemakers, W.H. Schreuder, M.B. Karakullukcu
Oral and Maxillofacial Surgery
Thu Jul 16, 2020 19:34
Risk Factors for Delayed Extubation Following High Posterior Cervical and Occipital Fusion
Background: Much has been written on initial airway management in patients undergoing cervical spine procedures, but comparatively less is known about extubation criteria. High cervical and occipital fusion procedures pose a particular risk for extubation given the potential for a reduced range of motion at the occiput-C1 and C1-C2 joints should reintubation be necessary. Materials and Methods: We performed a retrospective cohort analysis of posterior high cervical and occipital fusion...
Journal of Neurosurgical Anesthesiology - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Subsequent neoplasms in childhood cancer survivors
Publication date: October 2020Source: Cancer Epidemiology, Volume 68Author(s): Andrea Zichová, Tomáš Eckschlager, Marta Ganevová, Běla Malinová, Aleš Lukš, Jarmila Kruseová
ScienceDirect Publication: Cancer Epidemiology (open access)
Thu Jul 16, 2020 19:06
A rare case of duplicated appendix presenting as perforated appendicitis
AbstractAnomalies of the appendix have been reported mostly in adults as an incidental finding during surgery. The incidence of duplication of the vermiform appendix is reported to be 0.004% and <10 cases of appendicitis have been reported in duplicated appendix. This is a case report of an 18-year-old male who was diagnosed to have perforated appendicitis by imaging, and on open surgical exploration was found to have appendiceal duplication. Histopathological examination of both specimens revealed...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Colonic lavage in treatment of refractory Clostridium difficile infection: an adaptation of the Pittsburgh protocol
AbstractClostridium difficile infection (CDI) is a common nosocomial sequela in patients treated with antibiotics. Surgical intervention is indicated in fulminant cases. However, the mortality associated with total colectomy and end ileostomy is high. Previous reports have indicated that surgical intervention for severe complicated CDI with formation of a loop ileostomy leading to the diversion of fecal stream followed by colonic lavage can be beneficial in treating severe CDI. This procedure is...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Closed traumatic avulsion of both ring finger flexors with successful primary repair more than 4 weeks after injury and a review of the literature†
AbstractClosed flexor digitorum profundus (FDP) tendon avulsions are a recognized injury in hand surgery. However, closed tendon avulsion of both flexor tendons in the same digit is rare, with the few cases reported in the literature and presented here. Management includes primary repair ideally within the first 2 weeks to achieve optimal outcome. While beyond 4 weeks a two-stage repair is the dictum, we present a case where both tendons were avulsed but primary repair of the FDP was possible more...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Thoracoabdominal resection of giant malignant esophageal solitary fibrous tumor
AbstractSolitary fibrous tumor (SFT) is a rare mesenchymal neoplasm. It usually originates from the parietal pleura. SFT originating from the esophagus is exceedingly rare and even more so as a malignancy. We report a 57-year-old patient with a malignant 18 cm SFT of the esophagus that was treated with esophagectomy through a left thoracoabdominal incision. We discuss his surgical and oncologic management.
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Seizure as the first manifestation of transitional cell carcinoma of the renal pelvis
AbstractUpper tract urothelial carcinoma (UTUC) is a rare genitourinary entity of the renal pelvis and the ureter characterized by an aggressive behavior. Cisplatin-based chemotherapy is the first-line therapy of metastatic UTUC. However, a large number of patients with metastatic UTUC are considered ineligible for cisplatin. Immunotherapy emerged as a promising treatment in this setting. Brain metastasis from UTUC is unusual, occurring most often in the presence of systemic metastases. Local therapies...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
A unique case report of a high-pressure paint injection injury of the hand with associated carbapenemase resistant Pseudomonas aeruginosa infection
AbstractHigh pressure injection injuries to the hand should not be taken lightly as urgent surgical debridement is required to ensure favorable outcomes. Empiric antibiotic administration is recommended; however, few studies focus on the secondary infection risk associated with these high pressure injection injuries. We present a rare case of a patient presenting with carbapenem resistant Pseudomonas aeruginosa following a high pressure paint gun injury of the thumb. Urgent surgical debridement with...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Aspergillus-related lung mass masquerading as a lung tumour
ABSTRACTAspergillus is a common environmental pathogen. However, clinically significant disease only occurs in a small proportion of patients. Although rare in its occurrence, it remains a considerable cause of morbidity and mortality in certain cohorts of patients. We describe a rare case of Aspergillus disease masquerading as a primary lung malignancy. Computer tomography pulmonary angiogram scan demonstrated a right upper lobe 8 x 6.5 cm soft-tissue lesion. Positron emission tomography CT demonstrated...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Unusual pulmonary vein variant in a patient with right upper lobe lung cancer
AbstractIt is essential to understand individual pulmonary anatomy, and the relationship between the tumor and surrounding organ, when lung resection is conducted. Recently, many anomalous pulmonary venous variations have been detected using three-dimensional computed tomography (3D-CT). Herein, we report the case of a 62-year-old women with lung cancer and an anomalous right upper lobe pulmonary vein that drained into the left atrium between the pulmonary artery and bronchus. Preoperative 3D-CT...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Osteosarcoma of the frontal bone: a study of a rare case in a 17-year-old female
AbstractHead and neck osteosarcomas are infrequent and usually present in the third–fourth decades of life. However, they are extremely rare in the pediatric population. Primary involvement of the cranial vault, excluding the mandible and maxilla, is an exceedingly rare phenomenon; thus, the number of clinical studies published in the literature is limited. Because of the anatomy of the head, complete resection may be difficult to achieve. Furthermore, an aggressive surgical approach can cause a...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Pancreatic neuroendocrine tumor featuring growth into the main pancreatic duct and tumor thrombus within the splenic vein: a case report
AbstractA 48-year-old woman was admitted to our hospital because of upper abdominal pain. Computer tomography showed an enhancing mass in the pancreatic body, dilation of the main pancreatic duct (MPD) and a filling defect within the splenic vein. On the basis of the preoperative diagnosis of pancreatic body cancer, distal pancreatectomy was scheduled. The pancreas was divided along the left edge of the gastroduodenal artery; however, frozen pathological examination of the pancreatic stump was tumor...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
The use of dorsoradial forearm flap for the treatment of dorsal hand defect
AbstractGenerally dorsal hand defects are often closed with a flap. Dorsoradial forearm artery flap has generally been used in thumb defects; however, it can also be used in the reconstruction of dorsal hand defects thanks to its wide rotation arc and appropriate pedicle length. In this case report, we presented the outcome of a case where the dorsoradial forearm flap was applied to treat the dorsal hand defect. A 27-year-old patient was admitted to emergency room with trauma on hand. Fixation of...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Perianal basal cell carcinoma: a common cancer in an uncommon location
AbstractThis is a case of a perianal basal cell carcinoma, a common skin cancer in an unusual location. Our patient is a 67-year-old male with a perianal lesion. He first noticed this painless lesion 5 years prior to presentation and was having fecal incontinence and weight loss. He had a fully encompassing ulcerated lesion involving the entirety of the anal margin. We performed a biopsy that returned on pathology as a basal cell carcinoma. Due to the size of the lesion and his current nutritional...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
A rare case of signet ring cell carcinoma of the appendix
AbstractPrimary appendiceal carcinoma itself comprises less than 0.5% of all gastrointestinal malignant neoplasms. However, signet ring cell carcinoma of the appendix is an extremely rare subset of primary appendiceal carcinomas. This sub-type of appendiceal carcinoma represents only 4% of all appendiceal carcinomas. In this case report, we present a case of signet ring cell carcinoma found in a 65-year-old male patient which presented as acute appendicitis. He was diagnosed after a laparoscopic...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Delayed presentation of a traumatic descending thoracic aorta aneurysm as an aorto-oesophageal fistula
AbstractAorto-oesophageal fistula is a rarely described but life-threatening complication presenting with upper gastrointestinal haemorrhage. We present a case of a 58-year-old gentleman who presented to a peripheral hospital with a short duration of haematemesis and melaena and recent onset symptoms of dysphagia. This gentleman had a past medical history of alcohol excess and a history of trauma following a road traffic accident 38 years ago. Initial computer tomography scan demonstrated a large...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Chilaiditi syndrome: an unusual presentation in elderly man
AbstractChilaiditi syndrome is a radiological manifestation of a large bowel interposition between the liver and right hemidiaphragm that associated with gastrointestinal symptoms. We report a case of 78-year-old Saudi male with multiple comorbidities, presented to the emergency department with two episodes of passaging a large amount of fresh, bright blood per rectum. Later, the patient was diagnosed with Chilaiditi syndrome and managed with conservative measures. The presence of Chilaiditi signs...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Prophylaxis and treatment of acute and chronic postoperative inguinal pain (CPIP)—association of pain with compression neuropathy†
AbstractCan open inguinal hernia repair (OIHR) and tailored neurectomy (TN) be effective for prophylaxis of chronic postoperative inguinal hernia repair (CPIP) (I) and treatment of CPIP (II)? Patients with symptomatic primary inguinal hernia (I group 1) and secondary hernia with CPIP (II, groups 2–5) were investigated for postoperative complications and nerve damage. About, 98% of patients with OIHR with TN reported preoperative pain (I group 1, n = 388, recurrence rate 1%). There were 73 cases (II)...
Journal of Surgical Case Reports - current issue
Tue Jul 14, 2020 03:00
Aquaporin 4 is involved in chronic pain but not acute pain
Publication date: Available online 15 July 2020Source: Behavioural Brain ResearchAuthor(s): Guanyi Lu, Chong Pang, Ying Chen, Ning Wu, Jin Li
Behavioural Brain Research
Thu Jul 16, 2020 19:01
Posttraumatic Giant Intradiploic Epidermoid Cyst of Orbital Roof
Epidermoid cysts are rare benign tumors that account for 0.3% to 1.8% of all intracranial space-occupying lesions. They are usually congenital in origin and are thought to derived from ectodermal cell inclusions occurring during closure of the neural tube around third to fifth week of gestation. They are most commonly located in the cerebellopontine angle and the parasellar area, and their location in the diploic space is very rare. In this article, a case of giant epidermoid cyst located in the...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Natural Adhesion Blepharoplasty Technique
Nonincisional blepharoplasty is widely practiced to make natural double eyelids. However, this method has the disadvantage of the double fold loosening compared to incisional blepharoplasty. Many researchers have proposed a method of nonincisional blepharoplasty with lower risk of loosening. The authors innovated the method to induce spontaneous adhesion in a nonincisional blepharoplasty with induction of partial linear adhesions, and, therefore, lowering the risk of suture loosening. While performing...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Subperiosteal Orbital Hemorrhage: An Unusual Complication During Labor
Subperiosteal orbital hemorrhage in the postpartum period has been rarely reported. The authors herein present a female patient who developed acute-onset vertical diplopia, proptosis, mild retro-orbital pain, and restriction of upgaze immediately after labor. Neuroimaging revealed a subperiosteal hematoma along the right orbital roof. Diplopia, motility limitation, and retro-orbital pain gradually resolved in the following weeks. Subperiosteal orbital hematomas are a rare complication of labor, with...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Use of Kinesiography to Assess Mandibular Function Following Segmental Resection and Microvascular Reconstruction
Mandibular reconstruction has attained adequate morphological outcomes. However, some patients encounter difficulties in oral function and limited mandibular movements. An objective: evaluation has seldom featured actual kinetic measurements after mandibular reconstruction. Thirty patients who underwent mandibular reconstruction using bony free flap were enrolled in the study. Twenty-two patients were recruited after surgery and compared to a control group of 8 healthy subjects; 8 patients underwent...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Airflow of the Two-Port Velopharyngeal Closure: Study Using Computational Fluid Dynamics
Posterior pharyngeal flap palatoplasty is used to restore the function of velopharyngeal (VP) closure, after which 2 ports remain between the nasal and oral cavity. The authors hypothesized that the airflow dynamics of the upper airway is different in PPF patients compared to health subjects, who only has 1 movable port. Twenty adults who have multislice spiral computed tomography scan were included in this study. Two cylinders (radius, 2.00 mm; height, 4.5 mm) were used to recapitulate the 2-port...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Photogrammetric Analysis of Eyebrow and Eyelid Dimensions in Indian American Adults
In cosmetic surgery, knowledge of the average dimensions of periorbital features based on gender and ethnicity is essential to improve the patient appearance and maintain the ethnicity. The aim the study was to establish gender-specific periorbital anthropometric and anthroposcopic data for Indian Americans (IA) and to assess the statistically ethnic differences by comparing with published data of Malaysian Indians (MI). Evaluation of periorbital features was done on the standardized frontal photographs...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Open Reduction and Internal Fixation Strategy For Treatment of Comminuted Mandibular Fracture
Purpose: The aim of this study was to evaluate the treatment strategy of open reduction and internal fixation (ORIF) for comminuted mandibular fracture (CMF). Methods: Clinical studies about CMF were collected. Detailed information was extracted, and data were analyzed and merged from included articles. Results: Twelve studies, including 338 patients with CMF, were reported. A total of 256 patients receive ORIF among these 338 patients, and exhibited followed characteristics:...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Ultrasound-Activated Bioresorbable Osteosynthesis in the Treatment of Craniosynostosis
The purpose of this study is to estimate the incidence of fixation-related complications following ultrasound-activated biodegradable osteosynthesis (UBO) in the treatment of craniosynostosis. The authors searched MEDLINE, PubMed, Embase, Google Scholar, and Cochrane Library from January 2005 to January 2020 for clinical studies reporting the use of UBO for fixation in the treatment of craniosynostosis. The primary outcome was the incidence of fixation-related complications, including unstable fixation;...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00
Vascularized Composite Parietal Bone Flap for Immediate Reconstruction of a Hemi-Maxillectomy Defect in an Infant
Background: Surgical resection of maxillary tumors can result in defects that can be difficult to reconstruct by conventional means due to the complex functional and anatomic nature of the midface and lack of regional bone flap options in the head and neck. Many reconstructive methods have been used to repair maxillary defects, but the ideal technique for the reconstruction of hemi-maxillectomy defects in growing pediatric patients has yet to be determined. Methods: The authors present...
Journal of Craniofacial Surgery - Published Ahead-of-Print
Tue Jul 14, 2020 03:00

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