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Τρίτη 28 Ιουλίου 2020


Adult T-cell leukaemia/lymphoma in Brazil: A rare disease or rarely diagnosed?
Related Articles Adult T-cell leukaemia/lymphoma in Brazil: A rare disease or rarely diagnosed? Br J Haematol. 2020 02;188(4):e46-e49 Authors: Rosadas C, Puccioni-Sohler M, Oliveira ACP, Casseb J, Sousa M, Taylor GP PMID: 31743423 [PubMed - indexed for MEDLINE]
Rare Cancers
Tue Jul 28, 2020 13:36
Imaging of DICER1 syndrome.
Related Articles Imaging of DICER1 syndrome. Pediatr Radiol. 2019 10;49(11):1488-1505 Authors: Guillerman RP, Foulkes WD, Priest JR Abstract DICER1 syndrome is a highly pleiotropic tumor predisposition syndrome that has been increasingly recognized in the last 10 years. Diseases in the syndrome result from mutations in both copies of the gene DICER1, a highly conserved gene that is critically implicated in micro-ribonucleic acid (miRNA) biogenesis...
Rare Cancers
Tue Jul 28, 2020 13:36
Rare malignant liver tumors in children.
Related Articles Rare malignant liver tumors in children. Pediatr Radiol. 2019 10;49(11):1404-1421 Authors: Chavhan GB, Siddiqui I, Ingley KM, Gupta AA Abstract Malignant hepatic tumors in children are rare, comprising 1.3% of all pediatric malignancies. Following hepatoblastoma, hepatocellular carcinoma is the second most common. Other malignant hepatic tumors seen in childhood include those of mesenchymal origin including undifferentiated...
Rare Cancers
Tue Jul 28, 2020 13:36
Initial treatment of pediatric differentiated thyroid cancer: a review of the current risk-adaptive approach.
Related Articles Initial treatment of pediatric differentiated thyroid cancer: a review of the current risk-adaptive approach. Pediatr Radiol. 2019 10;49(11):1391-1403 Authors: Parisi MT, Khalatbari H, Parikh SR, Alazraki A Abstract Differentiated thyroid cancer in children is a rare disease, accounting for only 1.4% of all pediatric malignancies. The diagnosis, biological behavior and treatment of differentiated thyroid cancer in children...
Rare Cancers
Tue Jul 28, 2020 13:36
Retroviral sero-reactivity in LGL leukaemia patients and family members.
Related Articles Retroviral sero-reactivity in LGL leukaemia patients and family members. Br J Haematol. 2020 02;188(4):522-527 Authors: Nyland SB, Feith DJ, Poss M, Olson TL, Krissinger DJ, Poiesz BJ, Ruscetti FW, Loughran TP Abstract T-cell large granular lymphocyte (T-LGL) leukaemia is characterized by a clonal proliferation of cytotoxic T cells and is frequently associated with rheumatoid arthritis. Sera from some LGL leukaemia patients...
Rare Cancers
Tue Jul 28, 2020 13:36
[Breast Cancer in Men - Health Care Professionals' Perspectives on the Multidisciplinary Care of a Rare Disease].
Related Articles [Breast Cancer in Men - Health Care Professionals' Perspectives on the Multidisciplinary Care of a Rare Disease]. Gesundheitswesen. 2020 Jul;82(7):614-619 Authors: Ernstmann N, Midding E, Halbach S, Würstlein R, Weber R, Christmann S, Kowalski C Abstract AIM OF THE STUDY: Male breast cancer is a rare disease, for which, however, available care is from highly specialized care structures intended for female patients. So far,...
Rare Cancers
Tue Jul 28, 2020 13:36
Optimal first-line treatment for advanced thymic carcinoma.
Related Articles Optimal first-line treatment for advanced thymic carcinoma. Thorac Cancer. 2019 11;10(11):2081-2087 Authors: Yang X, Zhuo M, Shi A, Yang S, Wang Z, Wu M, An T, Wang Y, Li J, Zhong J, Chen H, Jia B, Dong Z, Zhao J Abstract BACKGROUND: Thymic carcinomas (TCs) are rare aggressive tumors with no standard first-line treatment. This study was conducted to determine the optimal chemotherapy regimen for advanced TC. METHODS:...
Rare Cancers
Tue Jul 28, 2020 13:36
Nonconventional Doses of Somatostatin Analogs in Patients With Progressing Well-Differentiated Neuroendocrine Tumor.
Related Articles Nonconventional Doses of Somatostatin Analogs in Patients With Progressing Well-Differentiated Neuroendocrine Tumor. J Clin Endocrinol Metab. 2020 01 01;105(1): Authors: Lamberti G, Faggiano A, Brighi N, Tafuto S, Ibrahim T, Brizzi MP, Pusceddu S, Albertelli M, Massironi S, Panzuto F, Badalamenti G, Riccardi F, Butturini G, Gelsomino F, De Divitiis C, Modica R, Bongiovanni A, La Salvia A, Torchio M, Colao A, Ferone D, Campana D Abstract...
Rare Cancers
Tue Jul 28, 2020 13:36
Anaplastic thyroid carcinoma mimicking a malignant pleural mesothelioma: Clues for diagnosis.
Related Articles Anaplastic thyroid carcinoma mimicking a malignant pleural mesothelioma: Clues for diagnosis. Thorac Cancer. 2019 11;10(11):2175-2178 Authors: Capron T, Giusiano S, Bourinet V, Laroumagne S, Dutau H, Astoul P Abstract Pleural metastasis of thyroid carcinoma is very rarely encountered in the evaluation of pleural effusion and diagnosis may be challenging. However, an anaplastic transformation of papillary thyroid carcinoma...
Rare Cancers
Tue Jul 28, 2020 13:36
Leiomyosarcoma with osteoclast-like (LMS-OGC) giant cells the breast: A report of a rare case.
Related Articles Leiomyosarcoma with osteoclast-like (LMS-OGC) giant cells the breast: A report of a rare case. Thorac Cancer. 2019 10;10(10):2054-2056 Authors: Xu Z, Gu J, Zhang S, Zhang Z, Fang W Abstract Leiomyosarcoma with osteoclast-like giant cells (LMS-OGC) has seldom been reported clinically. LMS-OGC of the breast is extremely rare according to the literature. Here, we report a case of LMS-OGC leiomyosarcoma with osteoclast-like giant...
Rare Cancers
Tue Jul 28, 2020 13:36
Successful treatment of thymic carcinoma with dermatomyositis and interstitial pneumonia: A case report.
Related Articles Successful treatment of thymic carcinoma with dermatomyositis and interstitial pneumonia: A case report. Thorac Cancer. 2019 10;10(10):2031-2034 Authors: Yang X, Yu L, Li F, Yu T, Zhang Y, Liu H Abstract Here, we report a rare case of thymic carcinoma (TC) associated with dermatomyositis (DM) and interstitial pneumonia (IP) in a 68-year-old man. The patient presented with the characteristic features of a skin rash with Gottron's...
Rare Cancers
Tue Jul 28, 2020 13:36
Diverse compositions and functions of chromatin remodeling machines in cancer.
Related Articles Diverse compositions and functions of chromatin remodeling machines in cancer. Sci Transl Med. 2019 07 17;11(501): Authors: Kadoch C Abstract Human cancer genetics power biochemical and functional interrogation of chromatin remodeling complexes, informing therapeutic opportunities. PMID: 31316005 [PubMed - indexed for MEDLINE]
Rare Cancers
Tue Jul 28, 2020 13:36
Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series.
Related Articles Rescue therapy for patients with anti-PD-1-refractory Merkel cell carcinoma: a multicenter, retrospective case series. J Immunother Cancer. 2019 07 08;7(1):170 Authors: LoPiccolo J, Schollenberger MD, Dakhil S, Rosner S, Ali O, Sharfman WH, Silk AW, Bhatia S, Lipson EJ Abstract Merkel cell carcinoma (MCC) is a rare but clinically aggressive cancer with a high mortality rate. In recent years, antibodies blocking the interactions...
Rare Cancers
Tue Jul 28, 2020 13:36
Hypothesis: does adrenalitis caused by immune checkpoint-inhibitors put melanoma patients at an elevated risk for recurrence?
Related Articles Hypothesis: does adrenalitis caused by immune checkpoint-inhibitors put melanoma patients at an elevated risk for recurrence? J Immunother Cancer. 2019 07 04;7(1):166 Authors: Harsch IA Abstract Primary adrenal failure (Addison's disease) is a rare complication of immune checkpoint inhibitor (ICI) therapy. Untreated - and also sometimes under adequate hydrocortisone replacement therapy - the levels of ACTH (Adrenocorticotropic...
Rare Cancers
Tue Jul 28, 2020 13:36
Prognosis of three histological subtypes of colorectal adenocarcinoma: A retrospective analysis of 8005 Chinese patients.
Related Articles Prognosis of three histological subtypes of colorectal adenocarcinoma: A retrospective analysis of 8005 Chinese patients. Cancer Med. 2019 07;8(7):3411-3419 Authors: Li C, Zheng H, Jia H, Huang D, Gu W, Cai S, Zhu J Abstract BACKGROUND AND OBJECTIVES: To evaluate the effect of the varied histological subtypes on clinical outcomes and to determine the prognostic implications of mucinous adenocarcinomas (MAC) and signet ring...
Rare Cancers
Tue Jul 28, 2020 13:36
Gemcitabine, dexamethasone, and cisplatin (GDP) chemotherapy with sandwiched radiotherapy in the treatment of newly diagnosed stage IE/IIE extranodal natural killer/T-cell lymphoma, nasal type.
Related Articles Gemcitabine, dexamethasone, and cisplatin (GDP) chemotherapy with sandwiched radiotherapy in the treatment of newly diagnosed stage IE/IIE extranodal natural killer/T-cell lymphoma, nasal type. Cancer Med. 2019 07;8(7):3349-3358 Authors: Tian S, Li R, Wang T, Wang S, Tao R, Hu X, Ding H Abstract Extranodal natural killer/T-cell lymphoma (ENKL), nasal-type is a rare but highly aggressive disease with poor prognosis. Optimal...
Rare Cancers
Tue Jul 28, 2020 13:36
Early Stage Extranodal Follicular Lymphoma: Characteristics, Management, and Outcomes.
Related Articles Early Stage Extranodal Follicular Lymphoma: Characteristics, Management, and Outcomes. Clin Lymphoma Myeloma Leuk. 2019 06;19(6):381-389 Authors: Andraos T, Ayoub Z, Nastoupil L, Pinnix C, Milgrom S, Gunther J, Ng SP, Fowler N, Neelapu S, Samaniego F, Dabaja B Abstract INTRODUCTION: Extranodal follicular lymphoma (E-FL) is a rare entity that has distinct characteristics and outcomes compared with nodal follicular lymphoma....
Rare Cancers
Tue Jul 28, 2020 13:36
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML).
Related Articles Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML). Cancer Biol Ther. 2019;20(6):877-885 Authors: Wu J, Wang A, Li X, Chen C, Qi Z, Hu C, Wang W, Wu H, Huang T, Zhao M, Wang W, Hu Z, Liu Q, Wang B, Wang L, Li L, Ge J, Ren T, Xia R, Liu J, Liu Q Abstract BCR fused ABL kinase is the critical...
Rare Cancers
Tue Jul 28, 2020 13:36
Systemic Immunotherapy for Advanced Cutaneous Squamous Cell Carcinoma.
Related Articles Systemic Immunotherapy for Advanced Cutaneous Squamous Cell Carcinoma. Curr Treat Options Oncol. 2019 03 14;20(4):30 Authors: Ogata D, Tsuchida T Abstract OPINION STATEMENT: Advanced (i.e., unresectable) cutaneous squamous cell carcinoma (cSCC) is a rare condition with a dismal prognosis. Although less than 5% of cSCC patients develop metastases or local recurrence after complete excision, advanced cSCC is difficult to treat....
Rare Cancers
Tue Jul 28, 2020 13:36
Current Update on the Molecular Biology of Cutaneous Sarcoma: Dermatofibrosarcoma Protuberans.
Related Articles Current Update on the Molecular Biology of Cutaneous Sarcoma: Dermatofibrosarcoma Protuberans. Curr Treat Options Oncol. 2019 03 14;20(4):29 Authors: Iwasaki T, Yamamoto H, Oda Y Abstract OPINION STATEMENT: Cutaneous sarcoma is a group of malignant mesenchymal tumors primarily involving the dermis, and it is characterized by extreme clinicopathological heterogeneity. Although its occurrence rate is rare, dermatofibrosarcoma...
Rare Cancers
Tue Jul 28, 2020 13:36
Clinical importance of FANCD2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas.
Related Articles Clinical importance of FANCD2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas. Cancer Biol Ther. 2019;20(6):843-854 Authors: Moes-Sosnowska J, Rzepecka IK, Chodzynska J, Dansonka-Mieszkowska A, Szafron LM, Balabas A, Lotocka R, Sobiczewski P, Kupryjanczyk J Abstract OBJECTIVE: DNA repair pathways are potential targets of molecular therapy in cancer patients. The FANCD2, BRIP1, BRCA1/2, and FANCF genes are involved...
Rare Cancers
Tue Jul 28, 2020 13:36
Acquired neuromyotonia in thymoma-associated myasthenia gravis: a clinical and serological study.
Related Articles Acquired neuromyotonia in thymoma-associated myasthenia gravis: a clinical and serological study. Eur J Neurol. 2019 07;26(7):992-999 Authors: Gastaldi M, De Rosa A, Maestri M, Zardini E, Scaranzin S, Guida M, Borrelli P, Ferraro OE, Lampasona V, Furlan R, Irani SR, Waters P, Lang B, Vincent A, Marchioni E, Ricciardi R, Franciotta D Abstract BACKGROUND AND PURPOSE: Acquired neuromyotonia can occur in patients with thymoma,...
Rare Cancers
Tue Jul 28, 2020 13:36
Treatment Outcomes of Pediatric Patients With Ewing Sarcoma in a War-Torn Nation: A Single-Institute Experience From Iraq.
Related Articles Treatment Outcomes of Pediatric Patients With Ewing Sarcoma in a War-Torn Nation: A Single-Institute Experience From Iraq. J Glob Oncol. 2019 01;5:1-9 Authors: Majeed SS, Muhammad HA, Ali JS, Khudhair HH, Said A, Arif SO, Murad KM, Gendari AH, Muhsin BM, Mohammed SA, Mula-Hussain L Abstract PURPOSE: Ewing sarcoma (ES) is a relatively rare, highly malignant tumor of the musculoskeletal system. It is the second most common malignant...
Rare Cancers
Tue Jul 28, 2020 13:36
Overcoming Biological Barriers in Neuroblastoma Therapy: The Vascular Targeting Approach with Liposomal Drug Nanocarriers.
Related Articles Overcoming Biological Barriers in Neuroblastoma Therapy: The Vascular Targeting Approach with Liposomal Drug Nanocarriers. Small. 2019 03;15(10):e1804591 Authors: Pastorino F, Brignole C, Di Paolo D, Perri P, Curnis F, Corti A, Ponzoni M Abstract Neuroblastoma is a rare pediatric cancer characterized by a wide clinical behavior and adverse outcome despite aggressive therapies. New approaches based on targeted drug delivery...
Rare Cancers
Tue Jul 28, 2020 13:36
HES1 Protein Modulates Human Papillomavirus-Mediated Carcinoma of the Uterine Cervix.
Related Articles HES1 Protein Modulates Human Papillomavirus-Mediated Carcinoma of the Uterine Cervix. J Glob Oncol. 2019 01;5:1-10 Authors: Tripathi R, Rath G, Sharma V, Hussain S, Sharma S, Bharadwaj M, Mehrotra R Abstract PURPOSE: Cervical cancer (CC) is the most common cancer affecting women worldwide. Human papillomavirus (HPV) infection is a major contributing factor for the development of CC. The development of CC occurs progressively...
Rare Cancers
Tue Jul 28, 2020 13:36

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