Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Purpose:To evaluate the performance of Delta4DVH Anatomy in patient-specific intensity-modulated radiotherapy quality assurance.Materials and Methods:Dose comparisons were performed between Anatomy doses calculated with treatment plan dose measured modification and pencil beam algorithms, treatment planning system doses, film doses, and ion chamber measured doses in homogeneous and inhomogeneous geometries. The...
Tue Jul 28, 2020 14:20
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Our study aimed to investigate the correlation of long noncoding RNA maternally expressed gene 3 expression with clinical features, treatment response, and survival profiles in patients with acute myeloid leukemia.Methods:Bone marrow samples of 122 de novo patients with acute myeloid leukemia (prior to treatment) and 30 healthy donors (after enrollment) were collected, and long noncoding RNA maternally...
Tue Jul 28, 2020 14:14
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background and Aims:Long noncoding RNA (small nucleolar RNA host gene 7) has been reported to be involved in multiple malignancies and acts as an oncogene. However, the potential mechanism of small nucleolar RNA host gene 7 in glioblastoma is rarely known. In this study, we attempted to elucidate the biological effects of small nucleolar RNA host gene 7 and the possible molecular mechanism in glioblastoma.Methods:The...
Tue Jul 28, 2020 14:11
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:To describe the clinical and pathological features of endometrial carcinoma with extraperitoneal metastasis and examine whether surgery could improve the prognosis.Methods:The Surveillance, Epidemiology, and End Results database was used to analyze 730 patients who were diagnosed with extraperitoneal metastasis of endometrial cancer from 2010 to 2015, including metastasis to the lung, bone, or brain.Results:Of...
Tue Jul 28, 2020 14:11
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:To explore the value of diffusion-weighted imaging for early response detection of locally advanced esophageal squamous cell carcinoma with concurrent chemoradiotherapy.Methods:Fifty-five (42 males, 13 females) patients with locally advanced esophageal cancer who were undergoing chemoradiotherapy were recruited for this study. Diffusion-weighted imaging was performed in all patients before therapy, at...
Tue Jul 28, 2020 13:02
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Abstract Paired-box (PAX) genes encode a family of highly conserved transcription factors found in vertebrates and invertebrates. PAX proteins are defined by the presence of a paired domain that is evolutionarily conserved across phylogenies. Inclusion of a homeodomain and/or an octapeptide linker subdivides PAX proteins into four groups. Often termed “master regulators”, PAX proteins orchestrate tissue and organ development throughout cell differentiation and lineage determination,...
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Diffuse large B-cell lymphoma (DLBCL) represents the most common form of non-Hodgkin lymphoma and is characterized by an aggressive natural history. It often presents with rapid symptom development and disease...
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Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1200-1482 Aims We investigated the quality of life (QoL), treatment satisfaction and perception of genetic results in participants with Maturity-Onset Diabetes of the Young (MODY) and compared the results with those of subjects with type 1 (T1D) or type 2 (T2D) diabetes. Methods A total of 162 adults with GCK-MODY, 62 with HNF1A-MODY and 29 ...
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1200-1528 Introduction Pseudotumor cerebri syndrome (PTCS) has anecdotally been described after successful treatment of Cushing’s disease (CD), but the prevalence following transsphenoidal surgery has not been determined so far in a prospective study. Patients and Methods 41 consecutive adult CD patients were prospectively screened...
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Background. Carcinoma of colon is rare in children and adolescents. The staging criteria of the carcinoma is the same as those for adults. However, the pathogenetic background in pediatric cases is different from adults and usually involves mismatch repair gene mutations or familial polyposis syndromes. Case report. We describe two adolescents diagnosed with advanced stage colon carcinoma and discuss the histological appearance, testing for mismatch repair genes and contrast- it with carcinoma occurring...
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High Altitude Medicine &Biology, Ahead of Print.
High Altitude Medicine &Biology, Ahead of Print.
High Altitude Medicine &Biology, Ahead of Print.
High Altitude Medicine &Biology, Ahead of Print.
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Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
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Abstract Proper alignment of acetabular implantation is necessary for good patient outcomes and preventing complications or additional surgeries in total hip arthroplasty (THA). Rotation of the pelvis in lateral decubitus (LD) is typically not accounted for as surgeons use the surgery table as a reference plane to align implants. This study compared four techniques to measure 3D pelvic rotations in LD position using computer models. CT scans of 19 subjects in LD position were used...
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Soft Robotics, Ahead of Print.
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (Covid-19), is responsible for the 2020 global pandemic. Developing a vaccine that is safe, effective, and rapidly deployable is an urgent global health priority. The majority of vaccine…
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Evolutionary and developmental biologists report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.
As climate change becomes increasingly difficult to ignore, scientists are working to diversify and improve alternatives to fossil-fuel-based energy. Renewable bioenergy crops, such as the perennial grass Miscanthus, show promise for cellulosic ethanol production and other uses, but current hybrids are limited by environmental conditions and susceptibility to pests and diseases.
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Rejuvenation Research, Ahead of Print.
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In this protocol, we describe a mouse model of incomplete surgical resection of soft tissue sarcoma for testing (neo)adjuvant therapies.
The goal of this publication is to demonstrate the potential application of a novel device using simulated solid organ injuries in a porcine model.
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We would like to thank Dr Boffetta for his comment on potential overlaps in the selection of cohorts. As we tried to keep the principle of examining all the available publications in the systematic review and avoiding the double count in the meta-analysis, we have re-examined the materials of the study again. Even though different aspects in the follow-ups of five cohorts were noted in the original review of 12 studies, we agree with Dr Boffetta that, on re-examination, there could be a potential...
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Publication date: Available online 27 July 2020Source: Allergology InternationalAuthor(s): Yoshitaka Ono, Shohei Obayashi, Yukihiro Horio, Kyoko Niimi, Naoki Hayama, Yoko Ito, Tsuyoshi Oguma, Koichiro Asano
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Background: Prior studies have shown an advantage for electro-acoustic stimulation (EAS) in cochlear implant (CI) patients with residual hearing, but the degree of benefit can vary. The objective was to explore which factors relate to performance with and acceptance of EAS for CI users with conventional-length electrodes. Methods: A retrospective chart review was conducted for adults with an average threshold of 75 dB hearing loss or better across 250 and 500 Hz preoperatively (n = 83). All patients...
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Publication date: Available online 28 July 2020Source: Pathology - Research and PracticeAuthor(s): Li-Yan Han, Jie-Ru Yang, Ze-Hua Zhao, Shuai Gao, Yu-Chen Fan, Kai Wang
Publication date: Available online 27 July 2020Source: Pathology - Research and PracticeAuthor(s): Nehal M. Elsherbiny, Mohamed El-Sherbiny, Sawsan A. Zaitone
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Metastatic ovarian cancer to the breast is a rare presentation, with limited cases reported worldwide. Common sites for distant metastasis in ovarian cancer are to the liver, lung, and pleura [Dauplat et al. Cancer. 1987 Oct 1;60(7):1561–6]. Usually, such cases predict poor prognosis with troublesome management. We present one challenging case of a 54-year-old female patient with recurrent clear cell ovarian cancer, presenting with right breast mass of primary versus secondary origin, progressing...
Off-label drug use refers to drug use beyond the specifications authorized for marketing [J Med Case Rep. 2014 Dec;8(1):303]. Eltrombopag is a thrombopoietin receptor agonist that has been used in treating thrombocytopenia due to chronic liver disease (CLD) as an off-label medication. Treatment of thrombocytopenia in patients with CLD constitute a real dilemma as the options are limited and some of them are invasive. However, thrombopoietin receptor agonist has been increasingly used for this purpose....
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Publication date: Available online 27 July 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Constanza Martínez, Flavio Zuccarino
Tue Jul 28, 2020 16:22
Publication date: Available online 27 July 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Laurien S. Kuhrij, Eleonora G. Karthaus, Anco C. Vahl, Martine C.M. Willems, Jan W. Elshof, Gert J. de Borst, P.J. Van den Akker, G.J. Akkersdijk, G.P. Akkersdijk, W.L. Akkersdijk, M.G. van Andringa de Kempenaer, C.H. Arts, J.A. Avontuur, O.J. Bakker, R. Balm, W.B. Barendregt, J.A. Bekken, M.H. Bender, B.L. Bendermacher, M. van den Berg
Tue Jul 28, 2020 16:22
Publication date: Available online 27 July 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Shady Zaki, Andrew Khallaf
Tue Jul 28, 2020 16:22
Publication date: Available online 27 July 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Michaela Kluckner, Andreas Frech
Tue Jul 28, 2020 16:22
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Publication date: Available online 27 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): William S. Silvers, Maeve O’Connor
Publication date: Available online 27 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Despotovic Milena, Jevtovic Stoimenov Tatjana, Stankovic Ivana, Basic Jelena, Djordjevic Branka
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