Related Articles p19INK4d inhibits proliferation and enhances imatinib efficacy through BCR-ABL signaling pathway in chronic myeloid leukemia. Blood Cells Mol Dis. 2020 Jul 14;85:102477 Authors: Kuang Y, Han X, Cao P, Xiong D, Peng Y, Liu Z, Xu Z, Liang L, Roy M, Liu J, Nie L, Zhang J Abstract Chronic myeloid leukemia (CML) is a kind of myeloproliferative disorder caused by a constitutively active BCR-ABL tyrosine kinase. Tyrosine kinase...
Tue Jul 28, 2020 13:45
Related Articles Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine. J Mol Cell Cardiol. 2020 Jul 22;: Authors: Velayutham N, Alfieri CM, Agnew EJ, Riggs KW, Baker RS, Ponny SR, Zafar F, Yutzey KE Abstract BACKGROUND: Rodent cardiomyocytes (CM) undergo mitotic arrest and decline of mononucleated-diploid population post-birth, which are implicated in neonatal loss of heart regenerative potential. However,...
Tue Jul 28, 2020 13:45
Related Articles Artemisinin and its derivatives: a promising cancer therapy. Mol Biol Rep. 2020 Jul 24;: Authors: Kiani BH, Kayani WK, Khayam AU, Dilshad E, Ismail H, Mirza B Abstract The world is experiencing a cancer epidemic and an increase in the prevalence of the disease. Cancer remains a major killer, accounting for more than half a million deaths annually. There is a wide range of natural products that have the potential to treat...
Tue Jul 28, 2020 13:45
Related Articles MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells. Clin Transl Oncol. 2020 Jul 25;: Authors: Das A, Henderson FC, Alshareef M, Porto GBF, Kanginakudru I, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D Abstract BACKGROUND: Glioblastoma (GB) remains an incurable and deadly brain malignancy that...
Tue Jul 28, 2020 13:45
Related Articles Modulatory Effect of Indoles on the Expression of miRNAs Regulating G1/S Cell Cycle Phase in Breast Cancer Cells. Appl Biochem Biotechnol. 2020 Jul 25;: Authors: El-Daly SM, Gamal-Eldeen AM, Gouhar SA, Abo-Elfadl MT, El-Saeed G Abstract Indole-3-carbinol (I3C) is a naturally occurring glucosinolate found in Brassica vegetables that is usually converted in gastric acidic environment to the efficient metabolite 3,3'-diindolylmethane...
Tue Jul 28, 2020 13:45
Related Articles TP5, a Peptide Inhibitor of Aberrant and Hyperactive CDK5/p25: A Novel Therapeutic Approach against Glioblastoma. Cancers (Basel). 2020 Jul 17;12(7): Authors: Tabouret E, Wang H, Amin N, Jung J, Appay R, Cui J, Song Q, Cardone A, Park DM, Gilbert MR, Pant H, Zhuang Z Abstract We examined the efficacy of selective inhibition of cyclin-dependent kinase 5 (CDK5) in glioblastoma by TP5. We analyzed its impact in vitro on CDK5...
Tue Jul 28, 2020 13:45
Related Articles Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells. Cancers (Basel). 2020 Jul 17;12(7): Authors: Ehrke-Schulz E, Heinemann S, Schulte L, Schiwon M, Ehrhardt A Abstract Human papillomaviruses (HPV) cause malignant epithelial cancers including cervical carcinoma, non-melanoma skin and head and neck cancer. They drive tumor development through...
Tue Jul 28, 2020 13:45
Related Articles Lactobacillus paracasei KW3110 Suppresses Inflammatory Stress-Induced Premature Cellular Senescence of Human Retinal Pigment Epithelium Cells and Reduces Ocular Disorders in Healthy Humans. Int J Mol Sci. 2020 Jul 18;21(14): Authors: Yamazaki T, Suzuki H, Yamada S, Ohshio K, Sugamata M, Yamada T, Morita Y Abstract Lactobacillus paracasei KW3110 (KW3110) has anti-inflammatory effects and mitigates retinal pigment epithelium...
Tue Jul 28, 2020 13:45
Related Articles A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb. Int J Mol Sci. 2020 Jul 18;21(14): Authors: Zhang B, Zhang T, Zhang TY, Wang N, He S, Wu B, Jin HX Abstract Chronic myeloid leukemia (CML) is a malignant tumor caused by the abnormal proliferation of hematopoietic stem cells. Among a new...
Tue Jul 28, 2020 13:45
Related Articles Senescence and Host-Pathogen Interactions. Cells. 2020 Jul 21;9(7): Authors: Humphreys D, ElGhazaly M, Frisan T Abstract Damage to our genomes triggers cellular senescence characterised by stable cell cycle arrest and a pro-inflammatory secretome that prevents the unrestricted growth of cells with pathological potential. In this way, senescence can be considered a powerful innate defence against cancer and viral infection....
Tue Jul 28, 2020 13:45
Related Articles In Vitro and In Vivo Antitumor Efficacy of Hizikia fusiforme Celluclast Extract against Bladder Cancer. Nutrients. 2020 Jul 21;12(7): Authors: Song JH, Won SY, Hwang B, Jung S, Choi C, Park SS, Choi YH, Kim WJ, Moon SK Abstract Various physiological benefits have been linked to Hizikia fusiforme (HF), an edible brown seaweed. Here, fucose-containing sulfated polysaccharides were extracted from celluclast-processed HF (SPHF)...
Tue Jul 28, 2020 13:45
Related Articles Chronic cypermethrin exposure alters mouse embryonic stem cell growth kinetics, induces Phase II detoxification response and affects pluripotency and differentiation gene expression. Eur J Histochem. 2020 Feb 17;64(1): Authors: Rebuzzini P, Civello C, Nantia Akono E, Fassina L, Zuccotti M, Garagna S Abstract Worldwide uncontrolled use of synthetic pyrethroids contaminates water and soil leading to health hazards. Cypermethrin...
Tue Jul 28, 2020 13:45
Related Articles High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase. Nucleic Acids Res. 2020 05 07;48(8):4274-4297 Authors: Cerritelli SM, Iranzo J, Sharma S, Chabes A, Crouch RJ, Tollervey D, El Hage A Abstract Cellular levels of ribonucleoside triphosphates (rNTPs) are much higher than those of deoxyribonucleoside triphosphates (dNTPs), thereby...
Tue Jul 28, 2020 13:45
Related Articles Design, synthesis and biological evaluation of benzimidazole derivatives as novel human Pin1 inhibitors. Bioorg Med Chem Lett. 2019 07 15;29(14):1859-1863 Authors: Ma T, Huang M, Li A, Zhao F, Li D, Liu D, Zhao L Abstract In this work, a series of novel benzimidazole derivatives were designed and synthesized as Pin1 inhibitors. Protease-coupled assay was used to investigate the Pin1 inhibitory potency of all synthesized compounds....
Tue Jul 28, 2020 13:45
50 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/07/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 28, 2020 17:28
50 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/07/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 28, 2020 13:51
Related Articles Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease. Front Neurosci. 2020;14:705 Authors: Lee YF, Gerashchenko D, Timofeev I, Bacskai BJ, Kastanenka KV Abstract Alzheimer's disease (AD) is the major cause of dementia, characterized by the presence of amyloid-beta plaques and neurofibrillary tau tangles. Plaques and tangles are associated with sleep-wake cycle disruptions, including the disruptions in non-rapid...
Tue Jul 28, 2020 13:55
Related Articles Functional MRI Signal Complexity Analysis Using Sample Entropy. Front Neurosci. 2020;14:700 Authors: Nezafati M, Temmar H, Keilholz SD Abstract Resting-state functional magnetic resonance imaging (rs-fMRI) is an immensely powerful method in neuroscience that uses the blood oxygenation level-dependent (BOLD) signal to record and analyze neural activity in the brain. We examined the complexity of brain activity acquired by rs-fMRI...
Tue Jul 28, 2020 13:55
Related Articles Short-Term Sensorimotor Deprivation Impacts Feedforward and Feedback Processes of Motor Control. Front Neurosci. 2020;14:696 Authors: Scotto CR, Meugnot A, Casiez G, Toussaint L Abstract Sensory loss involves irreversible behavioral and neural changes. Paradigms of short-term limb immobilization mimic deprivation of proprioceptive inputs and motor commands, which occur after the loss of limb use. While several studies have shown...
Tue Jul 28, 2020 13:55
Related Articles The Association Between Brain Volumes and Posttraumatic Stress Disorder in Intensive Care Unit Survivors: A Preliminary Study. Front Neurosci. 2020;14:690 Authors: Stepanovic K, Rogers B, Kiehl AL, Ely EW, Jackson J, Wilson JE, VISIONS Investigators and VISualizing Icu SurvivOrs Neuroradiological Sequelae Cohort Study Abstract Introduction: Millions of Americans are admitted to the intensive care unit (ICU) per year. Many survivors...
Tue Jul 28, 2020 13:55
Sustained Improvement of Negative Self-Schema After a Single Ketamine Infusion: An Open-Label Study.
Related Articles Sustained Improvement of Negative Self-Schema After a Single Ketamine Infusion: An Open-Label Study. Front Neurosci. 2020;14:687 Authors: Hasler G, Suker S, Schoretsanitis G, Mihov Y Abstract Conventional antidepressants have several important limitations, including a lack of direct effects on negative self-schema, which is at the core of Beck's cognitive theory of depression. Based on previous studies showing a positive effect...
Tue Jul 28, 2020 13:55
Related Articles Unpleasant Food Odors Modulate the Processing of Facial Expressions: An Event-Related Potential Study. Front Neurosci. 2020;14:686 Authors: Li D, Jia J, Wang X Abstract In real-life situations, emotional information is often expressed through multiple sensory channels, with cross-talk between channels. Previous research has established that odor environments regulate the recognition of facial expressions. Therefore, this study...
Tue Jul 28, 2020 13:55
Related Articles GABAergic Inhibitory Interneuron Deficits in Alzheimer's Disease: Implications for Treatment. Front Neurosci. 2020;14:660 Authors: Xu Y, Zhao M, Han Y, Zhang H Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary tangles. Abnormal amyloid β-protein (Aβ) deposition in the brain is often...
Tue Jul 28, 2020 13:55
Related Articles Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway. Front Neurosci. 2020;14:659 Authors: Malik I, Shah FA, Ali T, Tan Z, Alattar A, Ullah N, Khan AU, Alshaman R, Li S Abstract Ischemic stroke is a severe neurological disorder with a high prevalence rate in developed countries. It is characterized by permanent or transient cerebral ischemia and it activates...
Tue Jul 28, 2020 13:55
Related Articles Periodontitis Induced by P. gingivalis-LPS Is Associated With Neuroinflammation and Learning and Memory Impairment in Sprague-Dawley Rats. Front Neurosci. 2020;14:658 Authors: Hu Y, Li H, Zhang J, Zhang X, Xia X, Qiu C, Liao Y, Chen H, Song Z, Zhou W Abstract Background: Periodontitis is one of the most common oral diseases and is a potential risk factor for systemic diseases. In this study, we aimed to investigate the association...
Tue Jul 28, 2020 13:55
Related Articles Rhythmic Auditory Stimulation as an Adjuvant Therapy Improved Post-stroke Motor Functions of the Upper Extremity: A Randomized Controlled Pilot Study. Front Neurosci. 2020;14:649 Authors: Tian R, Zhang B, Zhu Y Abstract Objectives: To explore whether rhythmic auditory stimulation (RAS) could improve motor functions of post-stroke hemiparetic upper extremity. Design: A prospective, randomized controlled, assessor-blinded...
Tue Jul 28, 2020 13:55
Related Articles Heart Rate Variability as an Index of Differential Brain Dynamics at Rest and After Acute Stress Induction. Front Neurosci. 2020;14:645 Authors: Chand T, Li M, Jamalabadi H, Wagner G, Lord A, Alizadeh S, Danyeli LV, Herrmann L, Walter M, Sen ZD Abstract The brain continuously receives input from the internal and external environment. Using this information, the brain exerts its influence on both itself and the body to facilitate...
Tue Jul 28, 2020 13:55
Related Articles Fulminant Guillain-Barré Syndrome and Spontaneous Intraventricular Hemorrhage: A Case Report and Literature Review. Front Neurosci. 2020;14:633 Authors: Hu J, Luo X, Wang Y, Prado E, Fu Q, Shao A Abstract Guillain-Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy that is characterized by flaccid paralysis. A few cases have reported that GBS can be caused by head trauma or neurosurgery,...
Tue Jul 28, 2020 13:55
Related Articles Understanding Graph Isomorphism Network for rs-fMRI Functional Connectivity Analysis. Front Neurosci. 2020;14:630 Authors: Kim BH, Ye JC Abstract Graph neural networks (GNN) rely on graph operations that include neural network training for various graph related tasks. Recently, several attempts have been made to apply the GNNs to functional magnetic resonance image (fMRI) data. Despite recent progresses, a common limitation...
Tue Jul 28, 2020 13:55
Related Articles Can Short-Term Ocular Dominance Plasticity Provide a General Index to Visual Plasticity to Personalize Treatment in Amblyopia? Front Neurosci. 2020;14:625 Authors: Tao C, He Z, Chen Y, Zhou J, Hess RF Abstract Purpose: Recently, Lunghi et al. (2016) showed that amblyopic eye's visual acuity per se after 2 months of occlusion therapy could be predicted by a homeostatic plasticity, that is, the temporary shift of perceptual eye...
Tue Jul 28, 2020 13:55
Related Articles Aberrant Functional and Causal Connectivity in Acute Tinnitus With Sensorineural Hearing Loss. Front Neurosci. 2020;14:592 Authors: Cai Y, Xie M, Su Y, Tong Z, Wu X, Xu W, Li J, Zhao F, Dang C, Chen G, Lan L, Shen J, Zheng Y Abstract Purpose: The neural bases in acute tinnitus remains largely undetected. The objective of this study was to identify the alteration of the brain network involved in patients with acute tinnitus and...
Tue Jul 28, 2020 13:55
Related Articles A Systematic Review Establishing the Current State-of-the-Art, the Limitations, and the DESIRED Checklist in Studies of Direct Neural Interfacing With Robotic Gait Devices in Stroke Rehabilitation. Front Neurosci. 2020;14:578 Authors: Lennon O, Tonellato M, Del Felice A, Di Marco R, Fingleton C, Korik A, Guanziroli E, Molteni F, Guger C, Otner R, Coyle D Abstract Background: Stroke is a disease with a high associated disability...
Tue Jul 28, 2020 13:55
Related Articles Electrophysiological Effects of Transcranial Direct Current Stimulation on Neural Activity in the Rat Motor Cortex. Front Neurosci. 2020;14:495 Authors: Tanaka T, Isomura Y, Kobayashi K, Hanakawa T, Tanaka S, Honda M Abstract Transcranial direct current stimulation (tDCS) is a non-invasive technique that modulates the neuronal membrane potential. We have previously documented a sustainable increase in extracellular dopamine...
Tue Jul 28, 2020 13:55
Related Articles Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model. Evid Based Complement Alternat Med. 2020;2020:3205176 Authors: Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K, Wang J Abstract Electroacupuncture has been shown to promote remyelination in a demyelinating model of multiple sclerosis (MS) through enhanced microglial clearance of degraded myelin...
Tue Jul 28, 2020 13:29
Related Articles Optical imaging reveals functional domains in primate sensorimotor cortex. Neuroimage. 2020 Jul 22;:117188 Authors: Friedman RM, Chehade NG, Roe AW, Gharbawie OA Abstract Motor cortex (M1) and somatosensory cortex (S1) are central to arm and hand control. Efforts to understand encoding in M1 and S1 have focused on temporal relationships between neural activity and movement features. However, it remains unclear how the neural...
Tue Jul 28, 2020 13:29
65 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 28, 2020 14:16
65 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 28, 2020 13:16
Related Articles Evaluation of PD-L1, tumor-infiltrating lymphocytes, and CD8+ and FOXP3+ immune cells in HER2-positive breast cancer treated with neoadjuvant therapies. Breast Cancer Res Treat. 2020 Jul 26;: Authors: Zhao J, Meisel J, Guo Y, Nahta R, Hsieh KL, Peng L, Wei Z, O'Regan R, Li X Abstract BACKGROUND: The tumor immune microenvironment plays a critical role in the prognosis and outcome of breast cancers. This study examined the role...
Tue Jul 28, 2020 16:34
Related Articles 24-Dehydrocholesterol reductase promotes the growth of breast cancer stem-like cells through the Hedgehog pathway. Cancer Sci. 2020 Jul 26;: Authors: Qiu T, Cao J, Chen W, Wang J, Wang Y, Zhao L, Liu M, He L, Wu G, Li H, Gu H Abstract Cholesterol is a risk factor for breast cancer. However, it is still unclear whether the cholesterol biosynthesis pathway plays any significant role in breast carcinogenesis. 24-Dehydrocholesterol...
Tue Jul 28, 2020 16:34
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου