New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:03
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:02
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:02
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:01
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:01
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Jul 15, 2020 12:00
New England Journal of Medicine, Volume 383, Issue 3, Page 218-228, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 278-279, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 261-261, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 229-239, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 207-217, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 294-294, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 280-282, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 290-294, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 276-278, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 252-260, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 283-285, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 286-288, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 204-205, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, July 2020.
Wed Jul 15, 2020 11:55
New England Journal of Medicine, Volume 383, Issue 3, Page 240-251, July 2020.
Wed Jul 15, 2020 11:55
Acute kidney injury is a common complication in patients admitted to an intensive care unit (ICU) and is associated with a high risk of death or major complications and a high level of resource use. Many patients who are seriously ill undergo renal-replacement therapy; however, the appropriate…
Thu Jul 16, 2020 03:00
Among patients with an acute ischemic stroke or transient ischemic attack (TIA), the risk of a subsequent ischemic stroke is approximately 5 to 10% in the first few months. Aspirin has been used to prevent a stroke in these patients, and two trials have shown that the combination of aspirin and…
Thu Jul 16, 2020 03:00
High-potency topical glucocorticoids and vitamin D derivatives are the main treatments for psoriasis. Topical glucocorticoids are effective in the treatment of psoriasis, but their use is usually limited to no more than 2 to 8 weeks, and they may be associated with adverse events that resolve…
Thu Jul 16, 2020 03:00
Rheumatoid arthritis symptoms are highly dynamic, with periods of stability interrupted by unpredictable flares of disease activity. Such waxing and waning clinical courses are characteristic of many autoimmune diseases, including multiple sclerosis, systemic lupus erythematosus, and inflammatory…
Thu Jul 16, 2020 03:00
Rheumatoid arthritis, like many autoimmune diseases, has a course characterized by intermittent flares, yet our understanding of the mechanisms underlying flares remains limited. In an article published in this issue of the Journal, Orange and colleagues describe a study in which serial fingerstick…
Thu Jul 16, 2020 03:00
To the Editor: We propose a genetic epidemiologic metric derived from sequencing tumor cells and matched "normal" cells (typically peripheral-blood mononuclear cells); this metric can be used to evaluate the relevance of germline pathogenic variants (GPVs) in tumor-suppressor genes to the…
Thu Jul 16, 2020 03:00
Bilateral tumors in paired organs are assumed to be hereditary in nature, because a family history of cancer and an earlier age at onset are often associated with such tumors. These observations led Knudson to develop a seminal "two-hit" model that established a statistical basis for evaluating…
Thu Jul 16, 2020 03:00
Without urgent treatment, the risk of major stroke in the week after a transient ischemic attack (TIA) or minor stroke can be as high as 10%. Some studies have shown that immediate medical treatment with antiplatelet agents and statins, as well as blood-pressure control, reduces that risk by 70 to…
Thu Jul 16, 2020 03:00
"I know you are worried about Xin — all of us are, as well," I told the patient’s mother. "We are not sure why he is confused, but we are trying our best to find out. I cannot imagine how difficult it is for you, but our team will take care of both of you." I carefully selected an accurate Mandarin…
Thu Jul 16, 2020 03:00
Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author’s clinical recommendations. Stage. A 62-year-old,…
Thu Jul 16, 2020 03:00
Just as an active 2020 Atlantic hurricane season is getting under way, the entire U.S. hurricane coast, from Texas to the Carolinas, is witnessing explosive outbreaks of Covid-19 cases in communities where physical distancing restrictions have been eased. As an early wake-up call, Tropical Storm…
Wed Jul 15, 2020 03:00
Black, Latinx, and Native Americans are experiencing disproportionate burdens of infections, hospitalizations, and deaths from SARS-CoV-2 (Covid-19). Similar disparities are observed in other countries where minority groups face hurdles in accessing health, education, and social services as well as…
Wed Jul 15, 2020 03:00
To rapidly communicate short reports of innovative responses to Covid-19 around the world, along with a range of current thinking on policy and strategy relevant to the pandemic, the Journal has initiated the Covid-19 Notes series. Our critical access hospital in rural eastern Arizona provides…
Thu Jul 16, 2020 03:00
Suppose a large forest fire hits California. Millions of acres are burning, and many towns are threatened. The Forest Service firefighters are cutting breaks and dropping water from helicopters. They plan their strategy using weather models that predict which way wind patterns will push the fire.…
Wed Jul 15, 2020 03:00
More than 3 million people in the United States are known to have been infected with SARS-CoV-2. If every study registered on clinicaltrials.gov as of mid-June meets its target enrollment, less than 4% of those diagnosed with Covid-19 will have been enrolled in a randomized, controlled trial. In…
Wed Jul 15, 2020 03:00
The continuing spread of SARS-CoV-2 remains a Public Health Emergency of International Concern. What physicians need to know about transmission, diagnosis, and treatment of Covid-19 is the subject of ongoing updates from infectious disease experts at the Journal. In this audio interview conducted…
Thu Jul 16, 2020 03:00
Presentation of Case. Dr. Daniel A. Zlotoff: A 44-year-old woman was admitted to this hospital because of shortness of breath and chest pain. Eight days before admission — and 3 days after her husband had begun to have fatigue, a nonproductive cough, and a fever — the patient started to have…
Wed Jul 15, 2020 03:00
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