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Δευτέρα 12 Αυγούστου 2019

RESEARCH HIGHLIGHTS 

Settling down on chitin 
Andrea Du Toit 
p527 | doi:10.1038/s41579-019-0237-y Two papers provide novel insights into how Vibrio cholerae colonizes chitin, revealing the role of a type IV pilus and filamentation. 
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Phospholipid export from the inside out 
Andrea Du Toit 
p528 | doi:10.1038/s41579-019-0239-9 The results of this study suggest that the Mla pathway may be involved in anterograde phospholipid transport to the bacterial outer membrane. 
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Jumping from well to well 
Andrea Du Toit 
p528 | doi:10.1038/s41579-019-0240-3 This study explores the frequency of cross-contamination between samples in DNA sequence-based microbiome studies. 
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An intracellular drug reservoir 
Andrea Du Toit 
p528 | doi:10.1038/s41579-019-0241-2 This study reports that lipid droplets provide a reservoir for a lipophilic tuberculosis drug and enhance drug efficacy. 
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Debunking science deniers 
Ursula Hofer 
pp528 - 529 | doi:10.1038/s41579-019-0235-0 A new study investigates which strategies are effective to mitigate the effects of science denialism. 
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What’s the best bacterial shape? 
Ursula Hofer 
pp528 - 529 | doi:10.1038/s41579-019-0244-z A supercomputing study determines the optimal cell shape of free-swimming bacteria. 
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Causes of severe pneumonia in children 
Andrea Du Toit 
p529 | doi:10.1038/s41579-019-0245-y The Pneumonia Etiology Research for Child Health (PERCH) study reports the results of a case–control study to characterize the causes of pneumonia in children without HIV infection from Africa and Asia. 
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An effector with nuclease activity 
Andrea Du Toit 
p529 | doi:10.1038/s41579-019-0246-x This study identifies the first effector of contractile injection systems with nuclease activity that targets eukaryotic organisms. 
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Phages ensure their survival 
Andrea Du Toit 
p529 | doi:10.1038/s41579-019-0247-9 This study reports that transduction of antibiotic resistance genes and lysogeny contribute to the survival of transducing phages and their hosts. 
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NEWS & ANALYSIS

Genome gazing in ammonia-oxidizing archaea    
Emiley A. Eloe-Fadrosh 
p531 | doi:10.1038/s41579-019-0248-8 This month’s Genome Watch highlights the unique evolutionary history, metabolic functions, and newly identified viruses and associated mobile genetic elements for the highly abundant and ubiquitous ammonia-oxidizing archaea. 
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