Nature, Published online: 29 August 2019; doi:10.1038/d41586-019-02585-6Nearly half a million genomes reveal five DNA markers associated with sexual behaviour — but none with the power to predict the sexuality of an individual.
Thu Aug 29, 2019 03:00
Nature, Published online: 29 August 2019; doi:10.1038/d41586-019-02589-216,000-year-old artefacts discovered in Idaho could be the oldest ever found on the continent.
Thu Aug 29, 2019 03:00
Nature, Published online: 29 August 2019; doi:10.1038/d41586-019-02578-5India says its ‘no first use’ nuclear policy could change. Nature examines what that means for the country's fraught relationship with Pakistan.
Thu Aug 29, 2019 03:00
Nature, Published online: 28 August 2019; doi:10.1038/d41586-019-02579-4Robots that are roughly half a millimetre wide veer around sharp corners and down tiny corridors.
Wed Aug 28, 2019 03:00
Nature, Published online: 28 August 2019; doi:10.1038/d41586-019-02591-8Wanted: your huge underground warren. Plus, the world’s biggest carbon-nanotube chip and why PhDs should be more than just training for academia.
Wed Aug 28, 2019 03:00
Nature, Published online: 29 August 2019; doi:10.1038/d41586-019-02581-wElizabeth Gibney explores a remarkable Swedish science-fiction film featuring a spaceship fleeing a burning Earth.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-12061-4Author Correction: Discrepancy in scientific authority and media visibility of climate change scientists and contrarians
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11846-xCovalent organic frameworks are potential catalysts for nitrogen reduction, but limited nitrogen transport restricts the utilization ratio of active sites. Here, the authors demonstrate that electrochemical excitation of covalent organic frameworks can lead to efficient nitrogen reduction.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11735-3Non-additive genetic interactions are plastic and can complicate genetic prediction. Here, using deep mutagenesis of the lambda repressor, Li et al. reveal that changes in gene expression can alter the strength and direction of genetic interactions between mutations in many genes and develop mathematical models for predicting them.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11890-7Value of information analyses are a promising approach to decision-making in conservation. Here the authors develop a dynamic approach to show that knowing which species benefit from an ecosystem function improves ecosystem service and biodiversity management, particularly for risk-prone managers.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11902-6There is a growing interest in controlling the chemical process at molecular level. Here the authors show the mid-IR chirped pulse driven ground-state dissociation of condensed phase tungsten hexacarbonyl using efficient vibrational ladder climbing process by employing plasmonic near-field enhancement.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11905-3It is unclear why neuronal activity induced methylation changes are limited to specific loci in the genome. Here, authors show that the DNA demethylation enzyme, TET1, gains its specificity via the interaction with EGR1, a sequence specific DNA binding protein.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11841-2Systematic methods to characterize human mobility can lead to more accurate forecasting of epidemic spreading and better urban planning. Here the authors present a methodology to analyse daily commuting data by representing it with an irrotational vector field and a corresponding scalar potential.
Thu Aug 29, 2019 03:00
Nature Communications, Published online: 29 August 2019; doi:10.1038/s41467-019-11813-6Dysregulation of intracellular calcium is reported in Alzheimer’s disease. Here the authors show that loss of the mitochondrial Na+ /Ca2+ exchanger, NCLX – primary route of mitochondrial calcium efflux, precedes neuronal pathology in experimental models and contributes to Alzheimer’s disease progression.
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
The aim of this study was to determine the associations of body mass index (BMI) with all-cause and cause-specific disability retirement. Literature searches were conducted in PubMed, Embase and Web of Science from their inception to May 2019. A total of 27 (25 prospective cohort and 2 nested case-control) studies consisting of 2 199 632 individuals qualified for a meta-analysis. Two reviewers independently assessed the methodological quality of the included studies. We used a random effects meta-analysis,...
Thu Aug 29, 2019 19:00
In 2008, Professor Dame Carol Black1 published her groundbreaking report, Working for a Healthier Tomorrow (the Black Report), which contained 10 key recommendations to bring about positive change in the health of the working-age population in the UK (box 1). The government accepted her recommendations and promised to prioritise and invest in the health and work agenda.2 Just over a decade on, it is time to reflect on some of the progress made to date.Box 1Dame Carol Black’s review of the health...
Thu Aug 29, 2019 19:00
Oncogenesis, Published online: 29 August 2019; doi:10.1038/s41389-019-0155-xCorrection: ESRP1 is overexpressed in ovarian cancer and promotes switching from mesenchymal to epithelial phenotype in ovarian cancer cells
Thu Aug 29, 2019 03:00
Thu Aug 29, 2019 03:00
Background: Evaluation of surgical treatment for craniosynostosis is typically based on subjective visual assessment or simple clinical metrics of cranial shape that are prone to inter-observer variability. 3D photography provides cheap and non-invasive information to assess surgical outcomes, but there are no clinical tools to analyze it. We aim to objectively and automatically quantify head shape from 3D photography. Methods: We present an automatic method to quantify intuitive metrics...
Tue Aug 27, 2019 03:00
Background: Platelet-rich plasma (PRP) contains high concentrations of growth factors that stimulate proliferation and migration of various cell types. Earlier experiments demonstrated that local PRP administration activates Schwann cells (SCs) to improve axonal regeneration at a transected peripheral nerve lesion. However, the optimal concentration of human PRP for activation of human SCs (hSCs) has not been determined, while mechanisms by which PRP activates SCs remain to be clarified. Methods:...
Tue Aug 27, 2019 03:00
Background: Surgical delay can improve flap viability, leading to vasodilation, neovascularization, and vessel reorganization. Experiments suggest similar positive effect of botulinum toxin A (BTX-A) on pedicled flaps’ viability. However, whether it may convert the choke anastomoses into the true anastomoses and how to identify the optimal timing for flap transfer remains unclear. Methods: One hundred and fifty-four Sprague-Dawley rats were divided into a control group, three saline injection...
Tue Aug 27, 2019 03:00
Background: Although the distal targets have been lost in proximal upper-limb amputees, the neural signals for intuitive hand and arm function are still available and thus can be incorporated into more useful prosthetic function using Targeted Muscle Reinnervation (TMR) technique. Here we present our outcomes and range of indications as well as experiences and pitfalls after 30 TMR cases at above-elbow- and shoulder-disarticulation level of amputation. Methods: 30 patients with above-elbow...
Tue Aug 27, 2019 03:00
Background: Mature adipocytes dedifferentiate in vivo upon application of a soft tissue expander. Dedifferentiated adipocytes can proliferate and redifferentiate. In this study, adipose flaps were expanded, adipose tissue derived from them was transplanted into rats, and the retention rate was determined. We discuss how mechanical signals may induce dedifferentiation of mature adipocytes. Methods: A soft tissue expander and silicone sheet were implanted beneath the left and right inguinal...
Tue Aug 27, 2019 03:00
Background: Acellular dermal matrices (ADMs) have become a mandatory tool in reconstructive breast surgery. Since their introduction, they have been considered to be non-reactive and non-immunogenic scaffolds. However, some patients who undergo implant-based breast reconstruction with ADMs develop postoperative cutaneous erythema overlying their matrices, a condition commonly referred to as red breast syndrome. The aim of this study is to have a better understanding of this phenomenon. Methods:...
Tue Aug 27, 2019 03:00
Topography of the central retinal artery relevant to retrobulbar reperfusion in filler complications
Background: Vision loss due to retrograde occlusion of the central retinal artery is a serious complication of cosmetic filler injections. Salvation methods that involve applying hyaluronidases in the retrobulbar space to degrade filler materials have been proposed recently for rescuing the retinal circulation in an ophthalmic emergency. Methods: Sixty-six eyeballs and orbital contents were extracted from formalin-embalmed cadavers and dissected carefully to examine the topographic relationship...
Tue Aug 27, 2019 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου