Related ArticlesTrends in Mortality From Human Immunodeficiency Virus Infection, 1984-2016: An Autopsy-Based Study. Arch Pathol Lab Med. 2019 Aug 28;: Authors: Nizami S, Morales C, Hu K, Holzman R, Rapkiewicz A Abstract CONTEXT.—: With increasing use and efficacy of antiretroviral therapy for human immunodeficiency virus (HIV) infection, deaths from acquired immunodeficiency syndrome (AIDS)-defining conditions have decreased. OBJECTIVE.—: To...
Thu Aug 29, 2019 16:07
Related ArticlesThe circular RNA hsa-circ-0072309 plays anti-tumour roles by sponging miR-100 through the deactivation of PI3K/AKT and mTOR pathways in the renal carcinoma cell lines. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3638-3648 Authors: Chen T, Shao S, Li W, Liu Y, Cao Y Abstract Aims: To explore the roles and regulatory mechanisms of the circular RNA (circRNA)-hsa-circ-0072309 in CAKI-1 and ACHN cells. Methods: CAKI-1 and ACHN cells were...
Thu Aug 29, 2019 16:21
Related ArticlesApplication of biological variation and six sigma models to evaluate analytical quality of six HbA1c analyzers and design quality control strategy. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3598-3602 Authors: Wang X, Wen D, Wang W, Suo M, Hu T Abstract Objective: To apply biological variation and six Sigma models to evaluate analysis performance of 6 HbA1c analyzers and design the new quality control strategy. Method: We collected...
Thu Aug 29, 2019 16:21
Related ArticlesAnticarcinogenic potential of gold nanoparticles synthesized from Trichosanthes kirilowii in colon cancer cells through the induction of apoptotic pathway. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3577-3584 Authors: Han X, Jiang X, Guo L, Wang Y, Veeraraghavan VP, Krishna Mohan S, Wang Z, Cao D Abstract Gold nanoparticles (AuNPs) is the most excellent anticancer theranostic nanoparticles synthesized through efficient, simple and...
Thu Aug 29, 2019 16:21
Related ArticlesZinc oxide nanoparticles synthesized from Allium cepa prevents UVB radiation mediated inflammation in human epidermal keratinocytes (HaCaT cells). Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3548-3558 Authors: Wu F, Chen Y, Li G, Zhu D, Wang L, Wang J Abstract The extensive relevance of nanoparticles arouses the requirement for manufacturing although the predictable technique are frequently perilous and energy saving. In the current...
Thu Aug 29, 2019 16:21
Related ArticlesSinonasal inverted papilloma: rate of recurrence and malignant transformation in 44 operated patients. Braz J Otorhinolaryngol. 2019 Aug 12;: Authors: Sbrana MF, Borges RFR, Pinna FR, Neto DB, Voegels RL Abstract INTRODUCTION: Although sinonasal inverted papillomas are benign lesions, they are locally aggressive and have a potential malignant transformation ranging from 5% to 15%, with a high recurrence rate. OBJECTIVE: The aim...
Thu Aug 29, 2019 13:57
Related ArticlesThreshold Estimation Using "Chained Stimuli" for Cortical Auditory Evoked Potentials in Individuals With Normal Hearing and Hearing Impairment. Am J Audiol. 2019 Aug 28;28(2S):428-436 Authors: Kalaiah MK, Poovaiah S, Shastri U Abstract Purpose We investigated the utility of chained stimuli for threshold estimation using cortical auditory evoked potentials (CAEPs) in individuals with normal hearing sensitivity and hearing loss. The effect...
Thu Aug 29, 2019 15:58
Related ArticlesThe Application of the RNA Interference Technologies for KRAS: Current Status, Future Perspective and Associated Challenges. Curr Top Med Chem. 2019 Aug 28;: Authors: Shao YT, Ma L, Zhang TH, Xu TR, Ye YC, Liu Y Abstract KRAS is a member of the murine sarcoma virus oncogene-RAS gene family. It plays an important role in the prevention, diagnosis and treatment of tumors during tumor cell growth and angiogenesis. KRAS is the most commonly...
Thu Aug 29, 2019 15:57
Related ArticlesMechanisms of protective effects of SGLT2 inhibitors in cardiovascular disease and renal dysfunction. Curr Top Med Chem. 2019 Aug 28;: Authors: Liu B, Wang Y, Zhang Y, Yan B Abstract Type 2 diabetes mellitus is one of the most common form of the disease worldwide. Hyperglycemia and insulin resistance play key roles in type 2 diabetes mellitus. Renal glucose reabsorption is an essential feature in glycaemic control. Kidneys filter 160g...
Thu Aug 29, 2019 15:57
Related ArticlesKirsten Rat Sarcoma Viral Oncogene Homologue（KRAS） mutations in the occurrence and treatment of pancreatic cancer. Curr Top Med Chem. 2019 Aug 28;: Authors: Zhu Z, Xiao S, Hao H, Hou Q, Fu X Abstract Pancreatic cancer is a highly malignant tumor with a 5-year survival rate of less than 6% and incidence increasing year by year in global. Pancreatic cancer has a poor prognosis and a high recurrence rate almost same as the death rate. However,...
Thu Aug 29, 2019 15:57
Related ArticlesAuthors' correction for Euro Surveill. 2019;24(33). Euro Surveill. 2019 Aug;24(34): Authors: Eurosurveillance Editorial Team PMID: 31456561 [PubMed - in process]
Thu Aug 29, 2019 14:52
Related ArticlesSurveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. Euro Surveill. 2019 Aug;24(34): Authors: Hammerum AM, Justesen US, Pinholt M, Roer L, Kaya H, Worning P, Nygaard S, Kemp M, Clausen ME, Nielsen KL, Samulioniené J, Kjærsgaard M, Østergaard C, Coia J, Søndergaard TS, Gaini S, Schønning K, Westh H, Hasman...
Thu Aug 29, 2019 14:52
Related ArticlesIncreasing incubation periods during a prolonged monophasic Salmonella Typhimurium outbreak with environmental contamination of a commercial kitchen at Oslo Airport, Norway, 2017. Euro Surveill. 2019 Aug;24(34): Authors: Siira L, MacDonald E, Holmbakken GM, Sundar T, Meyer-Myklestad L, Lange H, Brandal LT, Naseer U, Johannessen GS, Bergsjø B, Espenhain L, Vold L, Nygård K Abstract In September 2017, a cluster of monophasic Salmonella...
Thu Aug 29, 2019 14:52
Related ArticlesAntimicrobial use trends, Israel, 2012 to 2017. Euro Surveill. 2019 Aug;24(34): Authors: Dickstein Y, Temkin E, Ben-David D, Carmeli Y, Schwaber MJ Abstract BackgroundIn 2012, Israel's National Center for Infection Control initiated a national stewardship programme that included mandatory annual reporting of antimicrobial use. Here we present nationwide Israeli data for the period 2012 to 2017.AimThe goal of this study was to detect trends...
Thu Aug 29, 2019 14:52
Related ArticlesLinked seasonal outbreaks of Salmonella Typhimurium among passerine birds, domestic cats and humans, Sweden, 2009 to 2016. Euro Surveill. 2019 Aug;24(34): Authors: Söderlund R, Jernberg C, Trönnberg L, Pääjärvi A, Ågren E, Lahti E Abstract In 2016, an outbreak of Salmonella Typhimurium (STm) with multilocus variable-number tandem repeat analysis (MLVA) profiles historically associated with passerine birds (2-[11-15]-[3-4]-NA-212) occurred...
Thu Aug 29, 2019 14:52
Related ArticlesPineal gland volumes are changed in patients with obsessive-compulsive personality disorder. J Clin Neurosci. 2019 Aug 24;: Authors: Atmaca M, Korucu T, Caglar Kilic M, Kazgan A, Yildirim H Abstract OBJECTIVE: In the present study, taking into consideration our previous studies showing an association on the neuroanatomy of OCD and obsessive-compulsive personality disorders (OCPD), we also decided to examine pineal gland volumes in patients...
Thu Aug 29, 2019 13:46
Related ArticlesEfficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne. J Dermatolog Treat. 2019 Aug 28;:1-6 Authors: Szymańska A, Budzisz E, Erkiert-Polguj A Abstract Background: Acne is a common, chronic, inflammatory disease of the pilosebaceous unit. It has a significant impact on patient quality of life, especially when lesions occur on cosmetically sensitive areas. Chemical peeling is a well-known option in the treatment...
Thu Aug 29, 2019 14:42
Related Articles[Analysis of facial asymmetry in patients with crooked noses]. Laryngorhinootologie. 2019 Aug 28;: Authors: Lindemann J, Schmadl A, Scheithauer MO, Hoffmann TK, Sommer F, Grossi AS, Stupp F Abstract BACKGROUND: Surgical management of crooked nose is challenging even for experienced rhino surgeons, although numerous techniques for correction have been described. Not infrequently, there is a facial asymmetry in addition to the crooked...
Thu Aug 29, 2019 16:13
Related ArticlesTime to oxygenation for cannula- and scalpel-based techniques for emergency front-of-neck access: a wet lab simulation using an ovine model. Anaesthesia. 2019 Sep;74(9):1153-1157 Authors: Rees KA, O'Halloran LJ, Wawryk JB, Gotmaker R, Cameron EK, Woonton HDJ Abstract Emergency front-of-neck access to achieve a percutaneous airway can be a life-saving intervention, but there is debate about the preferred technique. This prospective, observational...
Thu Aug 29, 2019 14:12
Related ArticlesStimmlippenknötchen. Laryngorhinootologie. 2018 Aug;97(8):527-528 Authors: Nawka T PMID: 30081414 [PubMed - indexed for MEDLINE]
Thu Aug 29, 2019 16:16
Related ArticlesProteomic Profiling of Enteroid Cultures Skewed toward Development of Specific Epithelial Lineages. Proteomics. 2018 08;18(16):e1800132 Authors: Luu L, Matthews ZJ, Armstrong SD, Powell PP, Wileman T, Wastling JM, Coombes JL Abstract Recently, 3D small intestinal organoids (enteroids) have been developed from cultures of intestinal stem cells which differentiate in vitro to generate all the differentiated epithelial cell types associated...
Thu Aug 29, 2019 14:12
Related ArticlesLaboratory testing and imaging in the evaluation of cranial cerebrospinal fluid leaks and encephaloceles. Curr Opin Otolaryngol Head Neck Surg. 2019 Oct;27(5):339-343 Authors: Lipschitz N, Hazenfield JM, Breen JT, Samy RN Abstract PURPOSE OF REVIEW: To summarize the current evidence on the diagnostic evaluation of cranial cerebrospinal fluid (CSF) leaks and encephaloceles, including laboratory testing and imaging studies. RECENT...
Thu Aug 29, 2019 16:31
Related ArticlesImmunotherapy for non-small cell lung cancer. JAAPA. 2019 Sep;32(9):37-42 Authors: Vafadar S Abstract Immunotherapy is a new genre of treatment for patients with advanced cancer. Initially approved for use in metastatic melanoma, immunotherapy has found a significant place in treating non-small cell lung cancer (NSCLC). Clinical trials using several combinations of immunotherapy are underway to help to determine the best treatment for...
Thu Aug 29, 2019 15:42
Related ArticlesCasting A Wide Net On Surgery: The Central Role of Neutrophil Extracellular Traps. Ann Surg. 2019 Aug 27;: Authors: Eustache JH, Tohme S, Milette S, Rayes RF, Tsung A, Spicer JD Abstract : Since their discovery, neutrophil extracellular traps (NETs) have been implicated in a broad array of functions, both beneficial and detrimental to the host. Indeed, NETs have roles in infection, sepsis, wound healing, thrombotic disease, and cancer...
Thu Aug 29, 2019 15:42
Related ArticlesOptimized modification of the eighth edition of AJCC TNM staging system for resected pancreatic ductal adenocarcinoma. Future Oncol. 2019 Aug 28;: Authors: Pu N, Yin L, Habib JR, Gao S, Hu H, Zhu Y, Wu Y, Yu J, Lou W Abstract Aim: To reassess the prognostic performance of the American Joint Committee on Cancer (AJCC) 8th edition for Pancreatic ductal adenocarcinoma (PDAC) and optimize the categorization of PDAC staging. Patients &...
Thu Aug 29, 2019 15:42
Related ArticlesElective Node Irradiation With Integrated Boost to the Prostate Using Helical IMRT-Clinical Outcome of the Prospective PLATIN-1 Trial. Front Oncol. 2019;9:751 Authors: Koerber SA, Winter E, Katayama S, Slynko A, Haefner MF, Uhl M, Sterzing F, Habl G, Schubert K, Debus J, Herfarth K Abstract Introduction: This prospective, non-randomized phase II trial aimed to investigate the role of additional irradiation of the pelvic nodes for patients...
Thu Aug 29, 2019 15:42
Related ArticlesApplication of Bayesian predictive probability for interim futility analysis in single-arm phase II trial. Transl Cancer Res. 2019 Jul;8(Suppl 4):S404-S420 Authors: Chen DT, Schell MJ, Fulp WJ, Pettersson F, Kim S, Gray JE, Haura EB Abstract Background: Bayesian predictive probability design, with a binary endpoint, is gaining attention for the phase II trial due to its innovative strategy. To make the Bayesian design more accessible,...
Thu Aug 29, 2019 15:42
Related ArticlesIndividual Based Model Links Thermodynamics, Chemical Speciation and Environmental Conditions to Microbial Growth. Front Microbiol. 2019;10:1871 Authors: Gogulancea V, González-Cabaleiro R, Li B, Taniguchi D, Jayathilake PG, Chen J, Wilkinson D, Swailes D, McGough AS, Zuliani P, Ofiteru ID, Curtis TP Abstract Individual based Models (IbM) must transition from research tools to engineering tools. To make the transition we must aspire to...
Thu Aug 29, 2019 15:42
Related ArticlesPembrolizumab for the treatment of diffuse large B-cell lymphoma. Expert Opin Biol Ther. 2019 Aug 28;:1-8 Authors: Sheikh S, Kuruvilla J Abstract Introduction: Pembrolizumab is a novel monoclonal antibody that targets the interaction between programmed cell death protein 1 (PD-1) and its ligand (PD-L1). Pembrolizumab has shown significant clinical efficacy in Hodgkin Lymphoma (HL), but results in non Hodgkin Lymphoma (NHL) are mixed....
Thu Aug 29, 2019 15:42
Related ArticlesBone Metastasis of Breast Cancer. Adv Exp Med Biol. 2019;1152:105-129 Authors: Tahara RK, Brewer TM, Theriault RL, Ueno NT Abstract Bone is the most common site of metastasis for breast cancer. Bone metastasis significantly affects both quality of life and survival of the breast cancer patient. Clinically, complications secondary to bone metastasis include pain, pathologic fractures, spinal cord compression, and hypercalcemia of malignancy....
Thu Aug 29, 2019 13:48
Related ArticlesAn analysis of genetic heterogeneity in untreated cancers. Nat Rev Cancer. 2019 Aug 27;: Authors: Reiter JG, Baretti M, Gerold JM, Makohon-Moore AP, Daud A, Iacobuzio-Donahue CA, Azad NS, Kinzler KW, Nowak MA, Vogelstein B Abstract Genetic intratumoural heterogeneity is a natural consequence of imperfect DNA replication. Any two randomly selected cells, whether normal or cancerous, are therefore genetically different. Here, we review...
Thu Aug 29, 2019 13:48
Related ArticlesChallenges and potential solutions to the evaluation, monitoring, and regulation of surgical innovations. BMC Surg. 2019 Aug 27;19(1):119 Authors: Roberts DJ, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, James MT, Mrklas KJ, Hemmelgarn BD, Manns B, Stelfox HT Abstract BACKGROUND: As it may be argued that many surgical interventions provide obvious patient benefits, formal, staged assessment of the efficacy and safety of surgical procedures...
Thu Aug 29, 2019 13:48
Related ArticlesPost-conization follow-up of patients with CIN 2/3 with different amount of distance to negative cone biopsy margin: a retrospective cohort study. J Obstet Gynaecol. 2019 Aug 28;:1-5 Authors: Giray B, Kabaca-Kocakusak C, Guray-Uzun M, Akis S Abstract The aim of this study was to investigate whether patients with CIN 2/3 with different amount of distance to negative cone biopsy margin differ in terms of post-conization follow-up results....
Thu Aug 29, 2019 13:48
Related ArticlesAdvances in the therapy of BRAFV600E metastatic colorectal cancer. Expert Rev Anticancer Ther. 2019 Aug 27;: Authors: Jin Z, Sinicrope FA Abstract Introduction: BRAFV600E metastatic colorectal cancer (CRC) is an aggressive tumor subset with an approximate 8% incidence. In these patients, standard chemotherapy has limited efficacy, and the recent development of novel targeted treatment regimens may significantly improve clinical outcome....
Thu Aug 29, 2019 13:48
Related ArticlesUse of the Secreted Proteome of Trametes versicolor for Controlling the Cereal Pathogen Fusarium langsethiae. Int J Mol Sci. 2019 Aug 26;20(17): Authors: Parroni A, Bellabarba A, Beccaccioli M, Scarpari M, Reverberi M, Infantino A Abstract Fusarium langsethiae is amongst the most recently discovered pathogens of small grains cereals. F. langsethiae is the main producer, in Europe, of T2 and HT-toxins in small grain cereals, albeit often...
Thu Aug 29, 2019 13:48
Related ArticlesThe HD-OCT Study May Be Useful in Searching for Markers of Preclinical Stage of Diabetic Retinopathy in Patients with Type 1 Diabetes. Diagnostics (Basel). 2019 Aug 26;9(3): Authors: Kołodziej M, Waszczykowska A, Korzeniewska-Dyl I, Pyziak-Skupien A, Walczak K, Moczulski D, Jurowski P, Młynarski W, Szadkowska A, Zmysłowska A Abstract The aim of the study was to analyze the thickness of individual retinal layers in patients with type 1...
Thu Aug 29, 2019 13:48
Related ArticlesUpper-Limb Diabetic Myonecrosis: Atypical Presentation of a Rare Complication. Am J Case Rep. 2019 Aug 28;20:1268-1272 Authors: Jalali Z, Sharif SK Abstract BACKGROUND Myonecrosis is an uncommon complication of poorly controlled diabetes, predominantly involving the lower limbs. It is an atypical presentation in the upper limbs. Here, we report a rare case with atypical involvement of the upper limbs. CASE REPORT A 53-year-old diabetic...
Thu Aug 29, 2019 13:46
Related ArticlesFolfiri-Aflibercept vs. Folfiri-Bevacizumab as Second Line Treatment of RAS Mutated Metastatic Colorectal Cancer in Real Practice. Front Oncol. 2019;9:766 Authors: Ottaiano A, Capozzi M, Tafuto S, De Stefano A, De Divitiis C, Romano C, Avallone A, Nasti G Abstract Background: There are no clinical studies comparing the efficacy of bevacizumab vs.aflibercept in association with folfiri in RAS mutated (RAS-M) metastatic colorectal cancer...
Thu Aug 29, 2019 15:17
Related ArticlesBCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors. Front Oncol. 2019;9:764 Authors: Pennisi MS, Stella S, Vitale SR, Puma A, Di Gregorio S, Romano C, Tirrò E, Massimino M, Antolino A, Siragusa S, Mannina D, Impera S, Musolino C, Mineo G, Martino B, Zammit V, Di Raimondo F, Manzella L, Stagno F, Vigneri P Abstract In Chronic Myeloid Leukemia (CML), successful treatment requires accurate molecular...
Thu Aug 29, 2019 15:17
Related ArticlesRecent Insights Into the Multiple Pathways Driving Non-alcoholic Steatohepatitis-Derived Hepatocellular Carcinoma. Front Oncol. 2019;9:762 Authors: Takakura K, Oikawa T, Nakano M, Saeki C, Torisu Y, Kajihara M, Saruta M Abstract The incidence of metabolic syndrome with fatty liver is spreading on a worldwide scale. Correspondingly, the number of patients with the hepatic phenotype of metabolic syndrome, non-alcoholic fatty liver disease...
Thu Aug 29, 2019 15:17
Related ArticlesProteasomes and Several Aspects of Their Heterogeneity Relevant to Cancer. Front Oncol. 2019;9:761 Authors: Morozov AV, Karpov VL Abstract The life of every organism is dependent on the fine-tuned mechanisms of protein synthesis and breakdown. The degradation of most intracellular proteins is performed by the ubiquitin proteasome system (UPS). Proteasomes are central elements of the UPS and represent large multisubunit protein complexes...
Thu Aug 29, 2019 15:17
Related ArticlesMechanism of Action and Clinical Efficacy of CDK4/6 Inhibitors in BRCA-Mutated, Estrogen Receptor-Positive Breast Cancers: Case Report and Literature Review. Front Oncol. 2019;9:759 Authors: Militello AM, Zielli T, Boggiani D, Michiara M, Naldi N, Bortesi B, Zanelli P, Uliana V, Giuliotti S, Musolino A Abstract Sensitivity to endocrine therapy of patients with estrogen receptor (ER)-positive metastatic breast cancer and germline BRCA1/2...
Thu Aug 29, 2019 15:17
Related ArticlesMicroRNAs as Therapeutic Targets in Nasopharyngeal Carcinoma. Front Oncol. 2019;9:756 Authors: Wang S, Claret FX, Wu W Abstract Nasopharyngeal carcinoma (NPC) is a malignancy of epithelial origin that is prone to local invasion and early distant metastasis. Although concurrent chemotherapy and radiotherapy improves the 5-year survival outcomes, persistent or recurrent disease still occurs. Therefore, novel therapeutic targets are needed...
Thu Aug 29, 2019 15:17
Related ArticlesSIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway. Front Oncol. 2019;9:754 Authors: Sun X, Wang S, Gai J, Guan J, Li J, Li Y, Zhao J, Zhao C, Fu L, Li Q Abstract Sirtuin 5 (SIRT5), a mitochondrial class III NAD-dependent deacetylase, plays controversial roles in tumorigenesis and chemoresistance. Accordingly, its role in ovarian cancer development...
Thu Aug 29, 2019 15:17
Related ArticlesMeta-Analysis of Astragalus-Containing Traditional Chinese Medicine Combined With Chemotherapy for Colorectal Cancer: Efficacy and Safety to Tumor Response. Front Oncol. 2019;9:749 Authors: Lin S, An X, Guo Y, Gu J, Xie T, Wu Q, Sui X Abstract This meta analysis evaluated the comparative safety and efficacy for the addition of Astragalus-based Chinese medicines combined with chemotherapy and chemotherapy alone for colorectal cancer (CRC)...
Thu Aug 29, 2019 15:17
Related ArticlesCarnosol, a Natural Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via a ROS-Dependent Proteasome Degradation of STAT3. Front Oncol. 2019;9:743 Authors: Alsamri H, El Hasasna H, Al Dhaheri Y, Eid AH, Attoub S, Iratni R Abstract We have previously demonstrated that carnosol, a naturally occurring diterpene, inhibited in vitro cell viability and colony growth, as well as induced cell cycle arrest, autophagy...
Thu Aug 29, 2019 15:17
Related ArticlesHealth-Related Quality of Life in Advanced Non-small Cell Lung Cancer: A Methodological Appraisal Based on a Systematic Literature Review. Front Oncol. 2019;9:715 Authors: Van Der Weijst L, Lievens Y, Schrauwen W, Surmont V Abstract Background: The majority of lung cancer patients are diagnosed with advanced non-small cell lung cancer (NSCLC), the bulk of which receive palliative systemic treatment with the goal to provide effective symptom...
Thu Aug 29, 2019 15:17
Related ArticlesA Risk Signature With Inflammatory and T Immune Cells Infiltration in Colorectal Cancer Predicting Distant Metastases and Efficiency of Chemotherapy. Front Oncol. 2019;9:704 Authors: Hu X, Li YQ, Ma XJ, Zhang L, Cai SJ, Peng JJ Abstract In order to accurately predict oncological outcomes of colorectal cancer (CRC), we established a risk signature with tumor infiltrating neutrophils and T immune cells for prognosis. A total of 276 CRC...
Thu Aug 29, 2019 15:17
Related ArticlesChest Magnetic Resonance Imaging Decreases Inter-observer Variability of Gross Target Volume for Lung Tumors. Front Oncol. 2019;9:690 Authors: Basson L, Jarraya H, Escande A, Cordoba A, Daghistani R, Pasquier D, Lacornerie T, Lartigau E, Mirabel X Abstract Purpose: PET/CT is a standard medical imaging used in the delineation of gross tumor volume (GTV) in case of radiation therapy for lung tumors. However, PET/CT could present some limitations...
Thu Aug 29, 2019 15:17
Related Articles[Expression and significance of MAPK/ERK in the specimens and cells of epithelial ovarian cancer]. Zhonghua Fu Chan Ke Za Zhi. 2019 Aug 25;54(8):541-547 Authors: Jiang XL, Gao JC, Jiang L, Zhang PX, Kang TJ, Sun Q, Qi WJ, Zhang QP, Guan HW, Shi H Abstract Objective: To detect phosphorylated-extracellular signal-regulated kinase (p-ERK1/2) protein expression in epithelial ovarian cancer and cell lines, and to examine the effects of mitogen-activated...
Thu Aug 29, 2019 14:47
Related ArticlesModeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity. Cell Rep. 2019 Aug 27;28(9):2345-2357.e5 Authors: Heijink AM, Everts M, Honeywell ME, Richards R, Kok YP, de Vries EGE, Lee MJ, van Vugt MATM Abstract Triple-negative breast cancers (TNBCs) display great diversity in cisplatin sensitivity that cannot be explained solely by cancer-associated DNA repair defects. Differential...
Thu Aug 29, 2019 14:47
Related ArticlesRole and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models. Chin Med J (Engl). 2019 Aug 27;: Authors: Jiang WW, Wang YM, Wang XY, Zhang Q, Zhu SM, Zhang CL Abstract BACKGROUND: Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment...
Thu Aug 29, 2019 14:47
Related ArticlesMiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome. Biochem Cell Biol. 2019 Aug 28;:1-9 Authors: Sun X, Su S, Zhang G, Zhang H, Yu X Abstract MicroRNA (miR)-204 is known to be associated with several different diseases. Polycystic ovary syndrome (PCOS) has the highest incidence rate among the endocrine disorders in females between the ages of 18 and 44....
Thu Aug 29, 2019 14:47
Related ArticlesCoordination-Driven Self-Assembly of Triazole-Based Apoptosis-Inducible Metallomacrocycles. ACS Omega. 2019 Jun 30;4(6):10810-10817 Authors: Singh J, Park DW, Kim DH, Singh N, Kang SC, Chi KW Abstract Ru(II)-metallomacrocycles containing 4-pyridyl-1,2,3-triazole moiety were realized by coordination-driven self-assembly. All new compounds were characterized by electrospray ionisation mass spectrometry, elemental analysis, and 1H and 13C...
Thu Aug 29, 2019 14:47
Related ArticlesDehydrocorydaline inhibits cell proliferation, migration and invasion via suppressing MEK1/2-ERK1/2 cascade in melanoma. Onco Targets Ther. 2019;12:5163-5175 Authors: Hu H, Dong Z, Wang X, Bai L, Lei Q, Yang J, Li L, Li Q, Liu L, Zhang Y, Ji Y, Guo L, Liu Y, Cui H Abstract Purpose: Alkaloids are naturally occurring chemical compounds that are widely distributed in plants, and have pharmaceutical values and low toxicity. In recent years,...
Thu Aug 29, 2019 14:47
Related ArticlesMolecular pathways related to the control of proliferation and cell death in 786-O cells treated with plumbagin. Mol Biol Rep. 2019 Aug 27;: Authors: Mancilla IA, Coatti GC, Biazi BI, Zanetti TA, Baranoski A, Marques LA, Corveloni AC, Lepri SR, Mantovani MS Abstract Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed,...
Thu Aug 29, 2019 13:48
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου